VIRsiRNAdb

SpecificityServer - An siRNA design program for determining siRNA specificity
Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

70 hits were found for CGUUUCUCCUGGCUCAGUU (31 guide strand hits and 39 sense strand hits.)

Hits to Guide strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_198461

LONRF2

6287

6305

a

G

U

U

U

C

U

C

C

U

G

G

g

U

C

A

G

c

g

79

4

11

false

<90%

12516

NM_194315

UBE2J2

328

346

C

G

a

U

U

C

U

C

C

U

G

G

C

U

C

A

G

c

c

72

3

14

c

false

<90%

2315

NM_032545

CFC1

52

70

C

G

U

U

U

C

U

C

C

U

G

G

C

U

g

A

G

g

a

67

3

14

c

false

<90%

1009

NM_001079530

LOC653275

221

239

C

G

U

U

U

C

U

C

C

U

G

G

C

U

g

A

G

g

a

67

3

14

c

false

<90%

1182

XM_001129783

LOC729260

201

219

u

G

U

U

U

C

U

C

C

U

G

G

C

U

C

u

G

U

g

66

3

14

c

false

<90%

1461

NM_020734

FAM80B

5623

5641

C

u

U

U

U

C

U

C

C

U

G

G

C

U

C

A

c

U

U

65

2

14

ac

false

<90%

5845

NR_002723

GABPAP

45117

45135

a

G

U

U

U

C

U

C

C

U

G

c

C

U

C

A

G

c

c

56

4

10

false

<90%

194142

NR_002723

GABPAP

58071

58089

u

G

U

U

U

C

U

C

C

U

G

u

C

U

C

A

G

c

c

56

4

10

false

<90%

194142

NM_006933

SLC5A3

6094

6112

u

G

a

U

U

C

U

C

C

U

G

G

C

U

C

A

u

U

U

54

3

13

c

false

<90%

11400

NM_031433

MFRP

337

355

C

G

c

U

U

C

U

C

C

U

G

G

C

U

C

u

G

U

g

49

3

12

c

false

<90%

2519

NM_001001914

OR2G3

436

454

u

c

U

a

U

C

U

C

C

U

G

G

C

U

C

A

G

U

g

44

4

14

bc

false

<90%

930

NM_030984

TBXAS1

717

735

a

c

c

U

U

C

U

C

C

U

G

G

C

U

C

A

u

U

U

43

4

13

c

false

<90%

1783

NM_001061

TBXAS1

717

735

a

c

c

U

U

C

U

C

C

U

G

G

C

U

C

A

u

U

U

43

4

13

c

false

<90%

1946

NR_003366

ANKRD20B

38844

38862

C

G

a

U

U

C

U

C

C

U

G

a

C

U

C

A

G

U

c

41

3

8

false

<90%

96524

NM_178153

DCX

6157

6175

C

G

a

U

U

C

U

C

C

U

G

c

C

U

C

A

G

U

c

41

3

8

false

<90%

9054

NM_178152

DCX

6172

6190

C

G

a

U

U

C

U

C

C

U

G

c

C

U

C

A

G

U

c

41

3

8

false

<90%

9069

NM_178151

DCX

6225

6243

C

G

a

U

U

C

U

C

C

U

G

c

C

U

C

A

G

U

c

41

3

8

false

<90%

9122

NM_000555

DCX

6509

6527

C

G

a

U

U

C

U

C

C

U

G

c

C

U

C

A

G

U

c

41

3

8

false

<90%

9406

NM_025082

CENPT

139

157

C

a

a

U

U

C

U

C

C

U

G

c

C

U

C

A

G

U

U

35

3

8

false

<90%

2360

NM_022151

MOAP1

1768

1786

C

u

a

U

U

C

U

C

C

U

G

c

C

U

C

A

G

U

U

35

3

8

false

<90%

2435

XM_001133842

LOC729446

2560

2578

C

u

U

U

c

C

U

C

C

U

G

G

C

U

C

A

G

U

a

32

3

13

bc

false

<90%

7377

NM_175863

ARID1B

4760

4778

C

u

U

U

c

C

U

C

C

U

G

G

C

U

C

A

G

U

a

32

3

13

bc

false

<90%

8087

NM_020732

ARID1B

4799

4817

C

u

U

U

c

C

U

C

C

U

G

G

C

U

C

A

G

U

a

32

3

13

bc

false

<90%

8126

NM_017519

ARID1B

4919

4937

C

u

U

U

c

C

U

C

C

U

G

G

C

U

C

A

G

U

a

32

3

13

bc

false

<90%

8246

XM_939905

LOC646471

511

529

a

G

U

U

U

a

U

C

C

U

G

G

C

U

C

A

G

c

c

27

4

11

c

false

<90%

2761

XM_929392

LOC646471

516

534

a

G

U

U

U

a

U

C

C

U

G

G

C

U

C

A

G

c

c

27

4

11

c

false

<90%

2810

NM_000751

CHRND

852

870

C

G

g

U

g

C

U

C

C

U

G

G

C

U

C

A

G

U

c

23

3

13

bc

false

<90%

1741

XM_943292

LOC648365

162

180

u

G

U

U

U

C

U

C

C

a

G

G

C

U

C

A

G

a

c

7

4

8

c

false

<90%

816

XM_931594

LOC643514

162

180

u

G

U

U

U

C

U

C

C

a

G

G

C

U

C

A

G

a

c

7

4

8

c

false

<90%

816

NM_001005209

MGC99813

1817

1835

g

G

U

U

U

C

U

C

C

a

G

G

C

U

C

A

G

c

c

7

4

8

c

false

<90%

2239

NM_000252

MTM1

476

494

C

G

U

U

U

C

c

C

C

U

G

G

C

U

C

A

c

a

g

2

4

9

c

false

<90%

3411

Hits to Sense strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_152414

BHLHB5

2191

2209

u

u

C

U

G

A

G

C

C

A

G

G

A

G

A

A

A

a

a

78

4

15

ac

false

<90%

3388

NM_022090

LOC63920

2559

2577

A

A

u

U

G

A

G

C

C

A

G

G

A

G

A

A

A

a

G

77

2

14

c

false

<90%

2808

NM_212535

PRKCB1

1007

1025

u

A

C

U

G

A

G

C

C

A

G

G

A

G

g

A

A

g

G

70

3

13

c

false

<90%

2319

NM_002738

PRKCB1

1007

1025

u

A

C

U

G

A

G

C

C

A

G

G

A

G

g

A

A

g

G

70

3

13

c

false

<90%

3411

NM_024577

SH3TC2

990

1008

u

u

a

U

G

A

G

C

C

A

G

G

A

G

A

A

A

a

G

64

4

14

c

false

<90%

26588

NM_002446

MAP3K10

1619

1637

A

g

C

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

c

60

3

14

ac

false

<90%

3428

NM_031439

SOX7

1029

1047

A

A

C

U

G

A

G

C

C

A

G

G

u

G

g

A

A

C

u

59

3

12

false

<90%

3219

XR_018058

LOC222103

568

586

c

u

C

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

c

58

4

14

ac

false

<90%

1520

XR_018801

LOC222103

568

586

c

u

C

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

c

58

4

14

ac

false

<90%

1520

XR_017450

LOC441218

568

586

c

u

C

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

c

58

4

14

ac

false

<90%

1520

XR_017231

LOC390601

536

554

c

u

C

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

u

58

4

14

ac

false

<90%

1526

XR_019144

LOC390601

536

554

c

u

C

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

u

58

4

14

ac

false

<90%

1526

NM_006849

PDIA2

1181

1199

u

c

C

U

G

A

G

C

C

A

G

G

A

G

A

u

A

C

c

55

4

13

c

false

<90%

1726

XM_937409

ZNF516

1890

1908

u

g

g

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

G

43

4

13

c

false

<90%

8815

XM_496278

ZNF516

1890

1908

u

g

g

U

G

A

G

C

C

A

G

G

A

G

A

A

g

C

G

43

4

13

c

false

<90%

8822

NR_002801

DKFZp686A1627

1099

1117

c

A

C

U

G

A

G

C

C

A

a

G

A

G

A

A

A

a

G

34

3

9

c

false

<90%

4614

NM_001024647

RAB3IP

6393

6411

g

g

C

U

G

A

G

u

C

A

G

G

A

G

A

A

A

C

G

24

3

11

bc

false

<90%

8839

NM_175624

RAB3IP

6801

6819

g

g

C

U

G

A

G

u

C

A

G

G

A

G

A

A

A

C

G

24

3

11

bc

false

<90%

9247

NM_022456

RAB3IP

6901

6919

g

g

C

U

G

A

G

u

C

A

G

G

A

G

A

A

A

C

G

24

3

11

bc

false

<90%

9347

NM_175625

RAB3IP

7090

7108

g

g

C

U

G

A

G

u

C

A

G

G

A

G

A

A

A

C

G

24

3

11

bc

false

<90%

9536

NM_175623

RAB3IP

7190

7208

g

g

C

U

G

A

G

u

C

A

G

G

A

G

A

A

A

C

G

24

3

11

bc

false

<90%

9636

NM_052990

IFT122

1216

1234

u

c

C

U

G

u

G

C

C

A

G

G

A

G

A

A

A

C

G

23

3

13

bc

false

<90%

3717

NM_018262

IFT122

1372

1390

u

c

C

U

G

u

G

C

C

A

G

G

A

G

A

A

A

C

G

23

3

13

bc

false

<90%

3837

NM_052989

IFT122

1549

1567

u

c

C

U

G

u

G

C

C

A

G

G

A

G

A

A

A

C

G

23

3

13

bc

false

<90%

4029

NM_052985

IFT122

1702

1720

u

c

C

U

G

u

G

C

C

A

G

G

A

G

A

A

A

C

G

23

3

13

bc

false

<90%

4182

NM_002562

P2RX7

3035

3053

g

g

C

U

G

A

G

a

C

A

G

G

A

G

A

A

A

C

a

19

4

10

bc

false

<90%

3155

NM_178140

PDZD2

909

927

c

u

C

U

G

A

a

C

C

A

G

G

A

G

A

A

A

C

a

15

4

11

bc

false

<90%

11659

NM_052931

SLAMF6

2594

2612

g

A

C

U

G

A

G

g

C

A

G

G

A

G

A

A

u

C

G

12

3

8

c

false

<90%

2776

XM_930505

LOC645676

3004

3022

g

A

C

U

G

A

G

g

C

A

G

G

A

G

A

A

u

C

G

12

3

8

c

false

<90%

3116

XM_941520

LOC645676

3004

3022

g

A

C

U

G

A

G

g

C

A

G

G

A

G

A

A

u

C

G

12

3

8

c

false

<90%

3116

NM_001037293

PALM2

4377

4395

g

A

C

U

G

A

G

g

C

A

G

G

A

G

A

A

u

C

G

12

3

8

c

false

<90%

9261

NM_053016

PALM2

4479

4497

g

A

C

U

G

A

G

g

C

A

G

G

A

G

A

A

u

C

G

12

3

8

c

false

<90%

9363

XR_017704

LOC401131

2868

2886

A

A

C

U

G

A

G

g

C

A

G

G

A

G

A

A

u

u

G

11

3

8

c

false

<90%

6056

NM_012310

KIF4A

2032

2050

A

A

C

U

G

A

a

C

C

A

G

G

A

G

A

u

A

C

G

7

2

8

c

false

<90%

4447

NM_001083625

ANKRD12

4196

4214

A

A

C

U

G

u

G

C

C

A

G

G

A

G

A

u

A

C

u

5

3

9

c

false

<90%

10459

NM_015208

ANKRD12

4265

4283

A

A

C

U

G

u

G

C

C

A

G

G

A

G

A

u

A

C

u

5

3

9

c

false

<90%

10528

NM_004599

SREBF2

1324

1342

A

A

C

U

G

c

G

C

C

A

G

G

A

G

A

A

c

a

u

5

4

10

c

false

<90%

4325

NM_005906

MAK

1311

1329

A

A

C

a

G

A

G

u

C

A

G

G

A

G

A

A

A

C

c

-3

3

10

bc

false

<90%

3830

NM_203451

LOC400120

1141

1159

A

A

C

U

G

A

G

C

C

u

G

c

A

G

A

A

A

C

u

-21

3

9

false

<90%

2887

---

3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 970
View matched accessions

3 prime seed match details

Accession	Gene name	Hits to this gene
NM_001042383	CEP63	3
NM_001042400	CEP63	3
NM_025180	CEP63	3
NM_021155	CD209	3
NM_005202	COL8A2	2
NM_175610	TJP1	2
NM_003257	TJP1	2
NM_020718	USP31	2
NM_020805	KLHL14	2
NM_015064	ERC1	2
NM_178039	ERC1	2
NM_178040	ERC1	2
NM_178038	ERC1	2
NM_178037	ERC1	2
NM_133374	ZNF618	2
NM_005969	NAP1L4	2
NM_015200	SCC-112	2
NM_001100399		2
NM_001008408	RBM33	2
NM_053043	PRR8	2
NM_001039938	INTS6	2
NM_014743	KIAA0232	2
NM_001100590		2
NM_001083591	CUGBP2	2
NM_001025077	CUGBP2	2
NM_006561	CUGBP2	2
NM_001025076	CUGBP2	2
NM_000393	COL5A2	2
NM_022048	CSNK1G1	2
NM_174937	TCERG1L	2
NM_002886	RAP2B	2
NM_001085377		2
NM_002387	MCC	2
NM_013433	TNPO2	2
NM_007144	PCGF2	2
NM_030806	C1orf21	2
NM_012121	CDC42EP4	2
NM_004339	PTTG1IP	2
NM_001319	CSNK1G2	2
NM_018921	PCDHGA9	2
NM_018923	PCDHGB2	2
NM_018929	PCDHGC5	2
NM_002588	PCDHGC3	2
NM_018917	PCDHGA4	2
NM_018918	PCDHGA5	2
NM_032088	PCDHGA8	2
NM_018915	PCDHGA2	2
NM_018922	PCDHGB1	2
NM_003736	PCDHGB4	2
NM_018927	PCDHGB7	2
NM_018924	PCDHGB3	2
NM_018914	PCDHGA11	2
NM_018920	PCDHGA7	2
NM_018913	PCDHGA10	2
NM_018916	PCDHGA3	2
NM_018926	PCDHGB6	2
NM_003735	PCDHGA12	2
NM_032403	PCDHGC3	2
NM_032092	PCDHGA11	2
NM_018912	PCDHGA1	2
NM_018919	PCDHGA6	2
NM_018925	PCDHGB5	2
NM_018928	PCDHGC4	2
XM_001125753	MUC3B	2
NM_170774	RASSF2	2
NM_014737	RASSF2	2
NM_030629	CMIP	2
NM_198390	CMIP	2
NM_016206	VGLL3	2
NM_173832	ZFP41	2
XM_941807	NHSL1	2
XM_496826	NHSL1	2
NM_001079514	UBN1	2
NM_016936	UBN1	2
NM_138793	CANT1	2
NM_024757	EHMT1	2
NM_000318	PXMP3	1
NM_001079867	PXMP3	1
NM_183230	IKZF3	1
NM_183229	IKZF3	1
NM_183231	IKZF3	1
NM_183228	IKZF3	1
NM_183232	IKZF3	1
NM_012481	IKZF3	1
NM_144571	CNOT6L	1
NM_020773	TBC1D14	1
NM_000437	PAFAH2	1
NM_031452	FAM103A1	1
NM_002235	KCNA6	1
NM_032153	ZIC4	1
XM_929034	LOC646074	1
NM_015980	HMP19	1
NM_018974	UNC93A	1
NM_014751	MTSS1	1
NM_024963	FBXL18	1
NM_022097	LOC63928	1
XM_371369	MIA3	1
XM_943876	MIA3	1
XM_943869	MIA3	1
XM_943873	MIA3	1
XM_496436	MIA3	1
XM_932541	MIA3	1
XM_932548	MIA3	1
NM_198551	MIA3	1
NM_004748	CCPG1	1
NM_020739	CCPG1	1
NM_004420	DUSP8	1
NM_152435	AMDHD1	1
NM_017676	ZH2C2	1
NM_199077	CNNM2	1
NM_080862	SPSB4	1
NM_001032731	OAS2	1
NM_003101	SOAT1	1
NM_015286	DMN	1
NM_145728	DMN	1
NM_001008397	LOC493869	1
NM_005000	NDUFA5	1
NM_001007546	FLJ46838	1
NM_138349	TP53I13	1
NM_001010870	TDRD6	1
NM_025134	CHD9	1
NM_024086	METT10D	1
NM_001010000	ARHGAP28	1
NM_145278	C1orf150	1
NM_004985	KRAS	1
NM_033360	KRAS	1
NM_015644	TTLL3	1
NM_001025930	TTLL3	1
NM_174911	FAM84B	1
NM_001083592	ROR1	1
NM_018411	HR	1
NM_005144	HR	1
NM_003932	ST13	1
NM_018157	RIC8B	1
NM_080737	SYTL4	1
NM_001286	CLCN6	1
NM_133625	SYN2	1
NM_020845	PITPNM2	1
NM_138959	VANGL1	1
NM_207306		1
NM_015035	ZHX3	1
NM_000849	GSTM3	1
NM_002604	PDE7A	1
NM_017556	FBLIM1	1
NM_001024216	FBLIM1	1
NM_001030288	SPN	1
NM_003123	SPN	1
NM_018706	DHTKD1	1
NM_032374	C14orf153	1
NM_018509	LRRC59	1
NM_006091	CORO2B	1
NM_006085	BPNT1	1
NM_152653	UBE2E2	1
NM_001099403		1
NM_020226	PRDM8	1
NM_004522	KIF5C	1
NM_171982	TRIM35	1
NM_015204		1
NM_144997	FLCN	1
NM_014647	KIAA0430	1
NM_021072	HCN1	1
NM_052917	GALNT13	1
NM_015168	C19orf7	1
NM_002999	SDC4	1
NM_021202	TP53INP2	1
NM_003948	CDKL2	1
NM_004624	VIPR1	1
NM_004610	TCP10	1
NM_004808	NMT2	1
NM_015939	CGI-09	1
NM_004200	SYT7	1
XM_943686	SYT7	1
NM_018026	PACS1	1
NM_198700	CUGBP1	1
NM_006560	CUGBP1	1
NM_001025596	CUGBP1	1
NM_139279	MCFD2	1
NM_001652	AQP6	1
NM_020133	AGPAT4	1
NM_006371	CRTAP	1
NM_203302	MGC70863	1
NM_203477	MGC70863	1
NM_138723	BCL2L14	1
NM_030766	BCL2L14	1
NM_138722	BCL2L14	1
NM_001025603	RFX5	1
NM_000449	RFX5	1
NM_178509	STXBP4	1
NM_181706	DPH4	1
NM_001364	DLG2	1
NM_007249	KLF12	1
NM_001039884	FLJ44894	1
NM_144991	C21orf29	1
NM_001080410	FBXO41	1
XM_001133261	FBXO41	1
NM_001012514	ITM2C	1
NM_030926	ITM2C	1
NM_001012516	ITM2C	1
NM_006951	TAF5	1
NM_004734	DCLK1	1
NM_001042682	RERE	1
NM_012102	RERE	1
NM_001042681	RERE	1
NM_014901	RNF44	1
NM_004136	IREB2	1
NM_134268	CYGB	1
NM_000975	RPL11	1
NM_001010851	ZNF766	1
NM_014667	VGLL4	1
NM_001017995	SH3PXD2B	1
NM_173598	KSR2	1
NM_001007232	INCA	1
XM_001133772	LOC731724	1
NM_173481	C19orf21	1
NM_153487	MDGA1	1
NM_015267	CUTL2	1
NM_139246	C9orf97	1
NM_152418	WDR21C	1
NM_018403	DCP1A	1
NM_174901	FAM9C	1
NM_205849	FAM9B	1
NM_174951	FAM9A	1
NM_021943	ZFAND3	1
NM_172169	CAMK2G	1
NM_001222	CAMK2G	1
NM_172173	CAMK2G	1
NM_172171	CAMK2G	1
NM_172170	CAMK2G	1
NM_001037165	FOXK1	1
NM_015526	CLIP3	1
NM_080836	STK35	1
NM_001109754		1
NM_002837	PTPRB	1
NM_018847	KLHL9	1
NM_006493	CLN5	1
NM_001128	AP1G1	1
NM_001030007	AP1G1	1
NM_173065	IL28RA	1
NM_173064	IL28RA	1
NM_170743	IL28RA	1
NM_006527	SLBP	1
NM_017991	FLJ10081	1
NM_015330	SPECC1L	1
NM_022066	UBE2O	1
NM_198271	LMOD3	1
NM_005257	GATA6	1
NM_005561	LAMP1	1
NM_001001557	GDF6	1
NM_005158	ABL2	1
NM_007314	ABL2	1
NM_001100108		1
NM_153034	ZNF488	1
NM_173214	NFAT5	1
NM_006599	NFAT5	1
NM_138714	NFAT5	1
NM_001113178		1
NM_138713	NFAT5	1
NM_152544	C4orf23	1
NM_012213	MLYCD	1
NM_015156	RCOR1	1
NM_012215	MGEA5	1
NM_015299	KIAA0323	1
NM_006231	POLE	1
NM_080605	B3GALT6	1
NM_012406	PRDM4	1
NM_004438	EPHA4	1
NM_001077350	C16orf35	1
NM_001039476	C16orf35	1
NM_001099455		1
NM_018340	FLJ11151	1
NM_003476	CSRP3	1
NM_024295	DERL1	1
NM_012067	AKR7A3	1
NM_002399	MEIS2	1
NM_172316	MEIS2	1
NM_170674	MEIS2	1
NM_170677	MEIS2	1
NM_172315	MEIS2	1
NM_001039570	KREMEN1	1
NM_001039571	KREMEN1	1
NM_002460	IRF4	1
NM_024811	FLJ12529	1
NM_002687	PNN	1
NM_013238	DNAJC15	1
NM_000283	PDE6B	1
NM_005440	RND2	1
NM_152754	SEMA3D	1
NM_002577	PAK2	1
NM_001742	CALCR	1
NM_030580	ZNF34	1
NM_020840		1
NM_000555	DCX	1
NM_178152	DCX	1
NM_178153	DCX	1
NM_178151	DCX	1
NM_138348	FAM105B	1
NM_014867	KBTBD11	1
NM_014705	DOCK4	1
NM_001800	CDKN2D	1
NM_079421	CDKN2D	1
XM_001133785	LOC729645	1
XM_001132530	LOC731156	1
NM_032508	TMEM185A	1
NM_004928	C21orf2	1
NM_001004333	MGC71993	1
NM_078467	CDKN1A	1
NM_000389	CDKN1A	1
NM_000817	GAD1	1
NM_024830	AYTL2	1
NM_198696	KRTAP10-3	1
NM_021809	TGIF2	1
NM_003292	TPR	1
NM_148957	TNFRSF19	1
NM_000390	CHM	1
NM_020432	PHTF2	1
NM_001012958	DISC1	1
NM_001013650	LOC389151	1
NM_153256	C10orf47	1
NM_032294	CAMKK1	1
NM_172206	CAMKK1	1
NM_001100122		1
NM_014963	SBNO2	1
NM_001048198	SNHG3-RCC1	1
NM_001048197	SNHG3-RCC1	1
NM_001048195	RCC1	1
NM_001269	RCC1	1
NM_001048194	RCC1	1
NM_001048199	SNHG3-RCC1	1
XM_001126310	LOC730551	1
XM_001130092	LOC729377	1
NM_000405	GM2A	1
NM_015071	ARHGAP26	1
NM_020911		1
NM_004321	KIF1A	1
NM_022756	C1orf149	1
NM_014468	VENTX	1
NM_021025	TLX3	1
NM_031287	SF3B5	1
NM_000963	PTGS2	1
NM_144726	RNF145	1
NM_004747	DLG5	1
NM_145644	MRPL35	1
NM_016622	MRPL35	1
NM_175736	FMNL3	1
NM_198900	FMNL3	1
NM_017908	ZNF446	1
NM_005898	CAPRIN1	1
NM_152995	NFXL1	1
XM_001125711	LOC730453	1
NM_052847	GNG7	1
XM_940069	PPP1R3E	1
XM_927029	PPP1R3E	1
NM_001360	DHCR7	1
NM_000029	AGT	1
NM_007030	TPPP	1
NM_001085460		1
NM_001085469		1
NM_001085465		1
NM_001085466		1
NM_001085462		1
NM_001085461		1
NM_001085458		1
NM_001085468		1
NM_001085463		1
NM_001085467		1
NM_001331	CTNND1	1
NM_001085459		1
NM_001085464		1
NM_032121	DKFZp564K142	1
XM_001128660	LOC728866	1
NM_025248	SNIP	1
NM_001013649	LOC388969	1
NM_194457	UBE2J2	1
NM_194315	UBE2J2	1
NM_058167	UBE2J2	1
NM_194458	UBE2J2	1
NM_003216	TEF	1
NM_001831	CLU	1
NM_203339	CLU	1
NM_020639	RIPK4	1
NM_001002027	ATP5G1	1
NM_005175	ATP5G1	1
NM_018306	TMEM40	1
NM_032682	FOXP1	1
NM_005517	HMGN2	1
NM_031488	L3MBTL2	1
NM_014850	SRGAP3	1
NM_001033117	SRGAP3	1
NM_018196	TMLHE	1
NM_019887	DIABLO	1
NM_138929	DIABLO	1
NM_138930	DIABLO	1
NM_004982	KCNJ8	1
NM_002763	PROX1	1
NM_012101	TRIM29	1
NM_007203	PALM2-AKAP2	1
NM_147150	PALM2-AKAP2	1
NM_001004065	AKAP2	1
NM_139057	ADAMTS17	1
XM_938853	LOC285484	1
XM_376303	LOC285484	1
NM_014987		1
XM_940375	KBTBD9	1
XM_001134449	KBTBD9	1
NM_201397	GPX1	1
NM_032023	RASSF4	1
NM_001109938		1
NM_145029	C6orf136	1
NM_001037331	LOC284274	1
NM_019855	CABP5	1
NM_015056	RRP1B	1
NM_006195	PBX3	1
NM_015937	PIGT	1
NM_025090	USP36	1
NM_001361	DHODH	1
NM_003848	SUCLG2	1
NM_020400	GPR92	1
NM_176081	TRDMT1	1
NM_004412	TRDMT1	1
NM_176083	TRDMT1	1
NM_001018100	Gcom1	1
NM_152451	Gcom1	1
NM_004319	ASTN1	1
NM_145858	CRYZL1	1
NM_198479	TPRX1	1
NM_004125	LOC552891	1
NM_001017998	GNG10	1
NM_016207	CPSF3	1
NM_032329	ING5	1
XM_941026	ING5	1
XM_001126273	LOC727773	1
NM_001098638		1
NM_015553	PIP3-E	1
NM_020401	NUP107	1
NM_001077619	LOC137886	1
NM_023928	AACS	1
NM_005618	DLL1	1
NM_018040	GPATCH2	1
NM_017817	RAB20	1
NM_004391	CYP8B1	1
NM_012325	MAPRE1	1
NM_014864	FAM20B	1
NM_203307	ZNF321	1
NM_017431	PRKAG3	1
NM_006037	HDAC4	1
NM_001010854	TTC7B	1
NM_002090	CXCL3	1
NM_175571	GIMAP8	1
NM_178841	RNF166	1
NM_001033910	TRAF5	1
NM_145759	TRAF5	1
NM_004619	TRAF5	1
NM_017931	FLJ20699	1
NM_030796	ECOP	1
XM_938287	LOC653930	1
NM_194247	HNRPA3	1
NM_014061	MAGEH1	1
NM_130466	UBE3B	1
NM_183415	UBE3B	1
NM_018144	SEC61A2	1
NM_003633	ENC1	1
NM_020466	LYRM2	1
NM_018156	VPS13D	1
NM_015378	VPS13D	1
NM_001012511	GOSR2	1
NM_015471	NSL1	1
NM_001042549	NSL1	1
NM_015245	ANKS1A	1
NM_001440	EXTL3	1
NM_001033081	MYCL1	1
NM_001033082	MYCL1	1
NM_001083962		1
NM_003199	TCF4	1
NM_152429	FGFBP3	1
NM_018593	SLC16A10	1
NM_181489	ZNF445	1
NM_005750	C4orf6	1
XM_001131007	LOC729678	1
XM_001127177	LOC730780	1
NM_022445	TPK1	1
NM_001042482	TPK1	1
NM_015257	KIAA0286	1
NM_013399	C16orf5	1
NM_032840	SPRYD3	1
XM_001134250	LOC732053	1
XM_001126849	LOC727900	1
NM_009588	LTB	1
NM_133334	WHSC1	1
NM_198389	PDPN	1
NM_006474	PDPN	1
NM_001006624	PDPN	1
NM_001006625	PDPN	1
NM_025195	TRIB1	1
NM_024817	THSD4	1
NM_014484	MOCS3	1
NM_032940	POLR2C	1
NM_001008662	CCBL2	1
NM_001008661	CCBL2	1
NM_018318	CCDC91	1
XM_037557	KIAA0984	1
XM_939476	KIAA0984	1
NM_144727	CRYGN	1
NM_012388	PLDN	1
NM_152335	C15orf27	1
NM_015557	CHD5	1
NM_001004325	KRTAP5-2	1
NM_001280	CIRBP	1
NM_005920	MEF2D	1
NM_153825	SLA/LP	1
NM_000937	POLR2A	1
NM_020309	SLC17A7	1
NM_002398	MEIS1	1
NM_004054	C3AR1	1
NM_018940	PCDHB7	1
NM_001206	KLF9	1
NM_014521	SH3BP4	1
NM_002645	PIK3C2A	1
NM_004937	CTNS	1
NM_020348	CNNM1	1
NM_201553	FGL1	1
NM_004467	FGL1	1
NM_201552	FGL1	1
NM_147203	FGL1	1
NM_016376	ANKFY1	1
NM_016538	SIRT7	1
XM_001132247	C1orf108	1
NM_024595	C1orf108	1
NM_001012302	TMEM16J	1
NM_018023	YEATS2	1
NM_201595	GTF2A1	1
NM_015859	GTF2A1	1
NM_014588	VSX1	1
NM_175078	KRT77	1
NM_207111	TRIAD3	1
NM_207116	TRIAD3	1
NM_015888	HOOK1	1
XM_939111	LOC650020	1
NM_002938	RNF4	1
NM_004302	ACVR1B	1
NM_053282	SH2D1B	1
NM_018225	SMU1	1
XM_379840	LOC402509	1
XM_935781	LOC402509	1
NM_001040661	SLC29A4	1
NM_153247	SLC29A4	1
NM_024043	DBNDD1	1
NM_001042610	DBNDD1	1
NM_001974	EMR1	1
NM_033310	KCNK4	1
NM_001113239		1
NM_022740	HIPK2	1
NM_152263	TPM3	1
NM_145102	ZKSCAN5	1
NM_014569	ZKSCAN5	1
XM_001134375	GPR109B	1
NM_006018	GPR109B	1
NM_015161	ARL6IP1	1
NM_024917	CXorf34	1
NM_001008783	SLC35D3	1
NM_002957	RXRA	1
NM_002779	PSD	1
NM_000148	FUT1	1
NM_032866	CGNL1	1
NM_024813	C1orf82	1
NM_023016	ANKRD57	1
NM_032515	BOK	1
NM_014611	MDN1	1
NM_006620	HBS1L	1
XM_942952	FLJ46284	1
XM_499123	FLJ46284	1
NM_017681	NUP62CL	1
NM_016257	HPCAL4	1
NM_018201	TBC1D13	1
NM_018669	WDR4	1
NM_033505	SELI	1
NM_022755	IPPK	1
NM_003045	SLC7A1	1
NM_000181	GUSB	1
NM_012393	PFAS	1
NM_001111319		1
NM_003659	AGPS	1
NM_007084	SOX21	1
NM_001100829		1
NM_001806	CEBPG	1
NM_001099272		1
NM_152733	BTBD9	1
NM_052893		1
NM_006096	NDRG1	1
NM_001098787		1
NM_016526	BET1L	1
NM_000747	CHRNB1	1
NM_003593	FOXN1	1
NM_030651	PRRT1	1
NM_024649	BBS1	1
XM_001131384	LOC646522	1
XM_933676	LOC646522	1
NM_006354	TADA3L	1
NM_005640		1
NM_030636	KIAA1706	1
NM_198406	PAQR6	1
NM_024897	PAQR6	1
NM_002997	SDC1	1
NM_001006946	SDC1	1
NM_001010984	C1orf124	1
NM_007189	ABCF2	1
NM_003644	GAS7	1
NM_201432	GAS7	1
NM_201433	GAS7	1
NM_001043318	C14orf43	1
NM_194278	C14orf43	1
NM_001040653	ZXDC	1
NM_005026	PIK3CD	1
NM_033315	RASL10B	1
NM_006888	CALM1	1
NM_003185	TAF4	1
NM_003298	NR2C2	1
NM_018051	WDR60	1
NM_005883	APC2	1
NM_001099694		1
NM_213654	ARMC8	1
NM_014154	ARMC8	1
NM_020205	OTUD7B	1
NM_014572	LATS2	1
NM_018361	AGPAT5	1
NM_001093772		1
NM_000222	KIT	1
NM_017454	STAU1	1
NM_004602	STAU1	1
NM_017452	STAU1	1
NM_001037328	STAU1	1
NM_017453	STAU1	1
NM_018182	C17orf63	1
NM_001077498	C17orf63	1
NM_000599	IGFBP5	1
NM_022459	XPO4	1
NM_032171		1
NM_001098802		1
NM_001082480	ZNF623	1
NM_014789	ZNF623	1
NM_015522	DYNC2LI1	1
NM_024989	PGAP1	1
NM_002845	PTPRM	1
NM_001105244		1
NM_004209	SYNGR3	1
XM_001128149	LOC730316	1
XM_001129924	LOC729316	1
NM_172020	POM121	1
NM_001008701	LPHN1	1
NM_014921	LPHN1	1
NM_024782	NHEJ1	1
NM_212555	C11orf38	1
NM_003021	SGTA	1
NM_033446	FAM125B	1
NM_198403	MMD2	1
NM_001100600		1
NM_020208	SLC6A20	1
NM_022405	SLC6A20	1
NM_001002233	RAB11FIP1	1
NM_025151	RAB11FIP1	1
NM_001002814	RAB11FIP1	1
NM_020648	TWSG1	1
NM_001029955	WDR21B	1
XM_936719	LOC647662	1
NM_004566	PFKFB3	1
NM_022151	MOAP1	1
XM_496575	FLJ14082	1
XM_936846	FLJ14082	1
NM_013994	DDR1	1
NM_013993	DDR1	1
NM_001954	DDR1	1
NM_005934	MLLT1	1
NM_025209	EPC1	1
NM_001093725		1
NM_207397	CD164L2	1
NM_020910		1
NM_004402	DFFB	1
NM_153693	HOXC6	1
NM_004503	HOXC6	1
NM_030634	ZNF436	1
NM_001077195	ZNF436	1
NM_181336	LEMD2	1
XM_932721	LOC653264	1
XM_931343	LOC653135	1
NM_000332	ATXN1	1
NM_032900	ARHGAP19	1
NM_015025	MYT1L	1
NM_080552	SLC32A1	1
NM_018145	FAM82C	1
NM_078483	SLC36A1	1
NM_032932	RAB11FIP4	1
NM_017550	MIER2	1
NM_001017405	MAEA	1
NM_005882	MAEA	1
NM_020761	KIAA1303	1
NM_145303	LOC202459	1
NM_016138	COQ7	1
NM_003786	ABCC3	1
NM_170750	PSMD10	1
NM_002814	PSMD10	1
NM_001008	RPS4Y1	1
NM_020764	CASKIN1	1
NM_025146	NAT13	1
NM_014112	TRPS1	1
NM_145733	SEPT3	1
NM_019106	SEPT3	1
NM_005476	GNE	1
NM_016319	COPS7A	1
NM_018645	HES6	1
NM_001006620	MAPKAP1	1
NM_001006619	MAPKAP1	1
NM_001006621	MAPKAP1	1
NM_024117	MAPKAP1	1
NM_001006617	MAPKAP1	1
NM_152597	FSIP1	1
NM_007146	VEZF1	1
NM_018194	HHAT	1
NM_173470	TMEM32	1
NM_012081	ELL2	1
NM_016617	UFM1	1
NM_005036	PPARA	1
NM_001001928	PPARA	1
NM_173468	MOBKL1A	1
NM_007058	CAPN11	1
NM_003468	FZD5	1
NM_002064	GLRX	1
XM_944898	LOC651738	1
NM_015991	C1QA	1
NM_002872	RAC2	1
NM_000097	CPOX	1
XM_001134396	LOC730254	1
NM_014149	HSPC049	1
NM_001731	BTG1	1
NM_134433	RFX2	1
NM_000635	RFX2	1
XM_001130815	LOC647859	1
XM_001127102	LOC647859	1
NM_002015	FOXO1A	1
NM_014141	CNTNAP2	1
NM_014839	LPPR4	1
NM_024524		1
NM_020122	KCMF1	1
XM_001133393	KCMF1	1
NM_001024455	RGAG4	1
NM_004349	RUNX1T1	1
NM_175634	RUNX1T1	1
NM_175635	RUNX1T1	1
NM_175636	RUNX1T1	1
XM_001128808	LOC730771	1
XM_001133407	LOC729407	1
NM_020967	NCOA5	1
NM_001098270		1
NM_002409	MGAT3	1
NM_173568	UMODL1	1
NM_001004416	UMODL1	1
NM_001001412	FAM26C	1
NM_025250	TTYH3	1
NM_178275	DKFZp434B1231	1
NM_182515	ZNF714	1
NM_000864	HTR1D	1
NM_004628	XPC	1
NM_017671	C20orf42	1
NM_001105205		1
NM_001105204		1
NM_001105203		1
NM_014328	RUSC1	1
NM_004822	NTN1	1
NM_004964	HDAC1	1
NM_012199	EIF2C1	1
NM_000322	PRPH2	1
NM_018045	BSDC1	1
NM_001025109	CD34	1
NM_001773	CD34	1
NM_001025266	LOC285382	1
NM_014562	OTX1	1
NM_003531	HIST1H3C	1
NM_020700		1
NM_014979	SV2C	1
NM_006237	POU4F1	1
NM_000876	IGF2R	1
NM_144613	COX6B2	1
NM_174892	CD300LB	1
NM_138367		1
NM_031479	INHBE	1
XM_001132013	ANKH	1
NM_012425	RSU1	1
NM_152724	RSU1	1
XM_001129825	LOC728817	1
XM_001129242	LOC731171	1
NM_005997	VPS72	1
NM_014646	LPIN2	1
NM_000208	INSR	1
NM_001079817	INSR	1
NM_013279	C11orf9	1
NM_033026		1
XM_927936	LOC644841	1
XM_935685	LOC641933	1
XM_938176	LOC644841	1
NM_005314	GRPR	1
NM_014268	MAPRE2	1
XM_372194	C1orf170	1
XM_936696	C1orf170	1
NM_018440	PAG1	1
NM_031910	C1QTNF6	1
NM_182486	C1QTNF6	1
NM_173551	ANKS6	1
NM_002699	POU3F1	1
NM_203395	IYD	1
NM_000391	TPP1	1
NM_015444	TMEM158	1
NM_014606	HERC3	1
NM_003391	WNT2	1
NM_178498	SLC5A12	1
NM_173647	RNF149	1
NM_002006	FGF2	1
NM_001100398		1
NM_015085	GARNL4	1
NM_002738	PRKCB1	1
NM_033107	GTPBP10	1
NM_001042717	GTPBP10	1
NM_014279	OLFM1	1
XM_001132315	LOC732226	1
NM_003742	ABCB11	1
NM_014989	RIMS1	1
NM_015305	ANGEL1	1
NM_005329	HAS3	1
NM_138357	CCDC109A	1
NM_005563	STMN1	1
NM_203401	STMN1	1
NM_203399	STMN1	1
NM_203316	DPAGT1	1
NM_001382	DPAGT1	1
NM_016332	SEPX1	1
NM_025015	HSPA12A	1
NM_015892	GALNAC4S-6ST	1
NM_001012761	RGMB	1
XM_944900	LOC643770	1
XM_931792	LOC643770	1
NM_025027	ZNF606	1
NM_004273	CHST3	1
NM_144636	CHCHD4	1
NM_001098502		1
NM_178540	C1QTNF9	1
NM_001002860	BTBD7	1
NM_033551	LARP1	1
NM_015315	LARP1	1
NM_001080485	ZNF275	1
NM_023110	FGFR1	1
NM_023106	FGFR1	1
NM_015850	FGFR1	1
NM_023111	FGFR1	1
NM_023105	FGFR1	1
NM_152417	TMEM68	1
NM_005877	SF3A1	1
NM_001005409	SF3A1	1
NM_018841	GNG12	1
NM_145159	JAG2	1
NM_002226	JAG2	1
NM_005191	CD80	1
NM_052869	TTYH2	1
NM_032646	TTYH2	1
NM_031409	CCR6	1
NM_004367	CCR6	1
NM_004251	RAB9A	1
XM_001126406	LOC727922	1
XM_001126391	LOC727922	1
XM_001126417	LOC727922	1
NM_054016	FUSIP1	1
NM_145321	OSBPL3	1
NM_145320	OSBPL3	1
NM_145322	OSBPL3	1
NM_015550	OSBPL3	1
NM_001003407	ABLIM1	1
NM_001003408	ABLIM1	1
NM_002313	ABLIM1	1
NM_006720	ABLIM1	1
NM_002945	RPA1	1
NM_199168	CXCL12	1
NM_001017923	C14orf28	1
XM_942121	LOC645843	1
XM_930419	LOC645843	1
NM_001039547	GK5	1
NM_016433	GLTP	1
NM_014469	HNRNPG-T	1
NM_001961	EEF2	1
NM_032272	MAF1	1
NM_014212	HOXC11	1
XM_932212	LOC644489	1
XM_945584	LOC652498	1
NM_022574	PERQ1	1
NM_004571	PKNOX1	1
NM_005461	MAFB	1
NM_001177	ARL1	1
NM_024533	CHST5	1
NM_021615	CHST6	1
NM_145663	DBF4B	1
XM_001128868	LOC731223	1
NM_005197	CHES1	1
NM_001085471		1
NM_001004346	MTHFD2L	1
NM_001018000	KIAA1026	1
NM_001017999	KIAA1026	1
NM_001018001	KIAA1026	1
NM_015209	KIAA1026	1
NM_001010888	ZC3H12B	1
NM_005159	ACTC1	1
NM_182398	RPS6KA5	1
NM_031418	TMEM16C	1
NM_001024457	RGPD1	1
NM_032493	AP1M1	1
NM_001619	ADRBK1	1
NM_000112	SLC26A2	1
NM_020868	DPP10	1
NM_001004360	DPP10	1
NM_020240	CDC42SE2	1
NM_001038702	CDC42SE2	1
NM_005668	ST8SIA4	1
NM_002260	KLRC2	1
NM_199169	TMEPAI	1
NM_199170	TMEPAI	1
NM_199171	TMEPAI	1
NM_020182	TMEPAI	1
NM_199004	ARRB2	1
NM_004313	ARRB2	1
NM_025107	MYCT1	1
NM_000027	AGA	1
NM_018439	IMPACT	1
NM_032510	PARD6G	1
NM_194442	LBR	1
NM_002296	LBR	1
NM_018313	PBRM1	1
NM_181042	PBRM1	1
NM_018165	PBRM1	1
NM_004128	GTF2F2	1
NM_014423	AFF4	1
NM_020771	HACE1	1
NM_004722	AP4M1	1
NM_153347	TMEM86A	1
NM_021146	ANGPTL7	1
NM_016621	PHF21A	1
NM_001101802		1
NM_198571	FLJ39237	1
NM_001003793	RBMS3	1
NM_001003792	RBMS3	1
NM_005370	RAB8A	1
NM_153689	FLJ38973	1
NM_001033521	CSTF1	1
NM_001033522	CSTF1	1
NM_001324	CSTF1	1
NM_152531	C3orf21	1
NM_004981	KCNJ4	1
NM_152868	KCNJ4	1
NM_006067	COX4NB	1
NM_152545	RASGEF1B	1
NM_021102	SPINT2	1
NM_021257	NGB	1
NM_000682	ADRA2B	1
NM_001012418	LOC340156	1
NM_032138	KBTBD7	1
NM_004183	BEST1	1
NM_001430	EPAS1	1
NM_032453		1
NM_006581	FUT9	1
NM_001042646	TRAK1	1
NM_000280	PAX6	1
NM_001604	PAX6	1
NM_015073	SIPA1L3	1
XM_926338	LOC642956	1
XM_938166	LOC642956	1
NM_001012515	FECH	1
NM_000140	FECH	1

---

Immunostimulatory motif search results

UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).

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Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

Parameter	Spec. Score cut-off	Colour	Comment
Hit to same gene		Colour	Hits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit	≥80	Colour	Hits are very likely to cause an off-target effect
Medium scoring hit	<80¸≥40	Colour	Hits with a small chance of causing an off target effect.
Low scoring hit		Colour	Hits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-off	Colour
Match	Colour
Wobble base pairs (G-U)	Colour
Critical bases (none)	Colour
0.6 bits	Colour
0.4 bits	Colour
0.2 bits	Colour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer

For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317