VIRsiRNAdb

SpecificityServer - An siRNA design program for determining siRNA specificity
Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

21 hits were found for GCUAAGGUGCUUGAGCUGC (11 guide strand hits and 10 sense strand hits.)

Hits to Guide strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_006313

USP15

2765

2783

c

u

a

A

A

G

G

U

G

C

U

U

c

A

G

C

U

G

C

56

4

9

false

<90%

4611

NM_014225

PPP2R1A

693

711

G

C

c

A

A

G

G

U

G

C

U

g

G

A

G

C

U

G

g

41

3

8

false

<90%

2357

NM_015250

BICD2

403

421

c

g

g

A

A

G

G

U

G

C

U

a

G

A

G

C

U

G

C

33

4

8

false

<90%

4625

NM_001003800

BICD2

403

421

c

g

g

A

A

G

G

U

G

C

U

a

G

A

G

C

U

G

C

33

4

8

false

<90%

6433

NM_003304

TRPC1

3406

3424

a

C

U

A

A

G

G

U

u

C

U

U

G

A

G

C

U

u

a

30

4

8

c

false

<90%

4077

NM_031883

PCDHAC2

610

628

a

g

U

A

A

a

G

U

G

C

U

U

G

A

G

C

U

G

g

18

4

12

bc

false

<90%

2655

NM_018899

PCDHAC2

850

868

a

g

U

A

A

a

G

U

G

C

U

U

G

A

G

C

U

G

g

18

4

12

bc

false

<90%

5684

NM_080730

HOM-TES-103

299

317

G

C

c

A

A

G

G

U

G

C

a

U

G

A

G

C

U

G

g

14

3

7

c

false

<90%

2671

NM_001039670

HOM-TES-103

299

317

G

C

c

A

A

G

G

U

G

C

a

U

G

A

G

C

U

G

g

14

3

7

c

false

<90%

2683

NM_032689

ZNF607

395

413

c

C

U

A

g

G

G

U

G

C

U

g

G

A

G

C

U

G

C

12

3

7

false

<90%

4352

NM_021946

BCORL1

3124

3142

c

C

U

A

A

G

a

U

G

C

c

U

G

A

G

C

U

G

C

-29

3

8

c

false

<90%

6740

Hits to Sense strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_020749

MTUS1

539

557

G

C

A

G

C

U

C

A

A

G

C

A

g

C

U

U

c

u

u

58

4

12

false

<90%

3738

NM_001001931

MTUS1

819

837

G

C

A

G

C

U

C

A

A

G

C

A

g

C

U

U

c

u

u

58

4

12

false

<90%

4018

NM_001001925

MTUS1

3030

3048

G

C

A

G

C

U

C

A

A

G

C

A

g

C

U

U

c

u

u

58

4

12

false

<90%

6229

NM_001001924

MTUS1

3192

3210

G

C

A

G

C

U

C

A

A

G

C

A

g

C

U

U

c

u

u

58

4

12

false

<90%

6391

NM_203288

RP9

144

162

G

C

A

G

C

U

C

A

A

G

C

A

C

C

U

g

g

a

g

42

4

15

c

false

<90%

1184

NM_024079

ALG8

358

376

c

C

A

G

C

U

C

A

A

G

g

A

C

C

U

U

A

c

u

29

4

9

c

false

<90%

1668

NM_001007027

ALG8

358

376

c

C

A

G

C

U

C

A

A

G

g

A

C

C

U

U

A

c

u

29

4

9

c

false

<90%

1743

NM_052876

BTBD14B

3577

3595

a

a

A

G

C

a

C

A

A

G

C

A

C

C

U

U

A

G

u

18

4

12

bc

false

<90%

4556

NM_014948

UBOX5

1528

1546

a

C

A

G

C

U

C

c

A

G

C

A

C

C

U

U

g

G

C

12

3

8

c

false

<90%

4346

NM_032829

C12orf34

378

396

c

C

A

G

C

a

C

A

A

G

C

A

C

C

U

c

A

G

C

8

3

9

c

false

<90%

2731

---

3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1141
View matched accessions

3 prime seed match details

Accession	Gene name	Hits to this gene
NM_003281	TNNI1	3
NM_207012	AP3M1	2
NM_012095	AP3M1	2
NM_012164	FBXW2	2
NM_022465	IKZF4	2
NM_006731	FCMD	2
NM_001079802	FCMD	2
NM_004845	PCYT1B	2
NM_001104590		2
NM_001104589		2
NM_001104587		2
NM_152270	SLFN11	2
NM_001104588		2
NM_005338	HIP1	2
NM_152754	SEMA3D	2
NM_198459	DENND2C	2
NM_022121	PERP	2
XM_940069	PPP1R3E	2
XM_927029	PPP1R3E	2
NM_024709	C1orf115	2
NM_032287	LDOC1L	2
NM_014703	VPRBP	2
NM_020448	NPAL3	2
NM_012279	ZNF346	2
NM_006621	AHCYL1	2
NM_172364	CACNA2D4	2
NM_005158	ABL2	2
NM_007314	ABL2	2
NM_001100108		2
NM_005329	HAS3	2
NM_145912	NFAM1	2
NM_001024843	TNRC6B	2
NM_015088	TNRC6B	2
NM_032268	ZNRF1	2
NM_144667	FLJ32894	2
NM_022497	MRPS25	2
NM_017919	STX17	2
NM_021913	AXL	2
NM_001699	AXL	2
NM_020718	USP31	2
NM_006301	MAP3K12	2
NM_004756	NUMBL	2
NM_005779	LHFPL2	2
NM_033121	ANKRD13A	2
NM_001043318	C14orf43	2
NM_194278	C14orf43	2
NM_153045	C9orf91	1
NM_017582	UBE2Q1	1
NM_032547	SCOC	1
NM_152349	KRT222P	1
NM_014864	FAM20B	1
NM_145733	SEPT3	1
NM_019106	SEPT3	1
NM_001042599	ERBB4	1
NM_005235	ERBB4	1
XM_943029	LOC389043	1
XM_374012	LOC389043	1
NM_020447	C15orf17	1
NM_177549	PRNT	1
NM_174891	C14orf79	1
NM_173497	HECTD2	1
NM_032571	EMR3	1
NM_022353	OSGEPL1	1
NM_173582	PGM2L1	1
NM_003918	GYG2	1
NM_001079855	GYG2	1
NM_017596	KIF21B	1
NM_002829	PTPN3	1
NM_001012515	FECH	1
NM_000140	FECH	1
NM_024077	SECISBP2	1
NM_001003407	ABLIM1	1
NM_001003408	ABLIM1	1
NM_002313	ABLIM1	1
NM_006720	ABLIM1	1
NM_178498	SLC5A12	1
XM_291671	RBM20	1
XM_939337	RBM20	1
NM_031954	KCTD10	1
NM_015156	RCOR1	1
NM_015132	SNX13	1
NM_003954	MAP3K14	1
NM_015313	ARHGEF12	1
NM_001083620	GRIA2	1
NM_000826	GRIA2	1
NM_001083619	GRIA2	1
NM_005590	MRE11A	1
NM_005591	MRE11A	1
NM_182970	RIMS4	1
NM_015348		1
NM_014987		1
NM_001859	SLC31A1	1
NM_022454	SOX17	1
NM_174917	LOC197322	1
NM_016204	GDF2	1
NM_178550	C1orf110	1
NM_020855		1
NM_000129	F13A1	1
NM_152860	SP7	1
NM_016083	CNR1	1
NM_033181	CNR1	1
NM_002761	PRM1	1
NM_152495	CNIH3	1
NM_001104647		1
NM_018155	SLC25A36	1
NM_024624	SMC6	1
NM_001039770	FLJ45032	1
NM_014752	SPCS2	1
NM_019035	PCDH18	1
NM_018638	ETNK1	1
NM_153321	PMP22	1
NM_000304	PMP22	1
NM_153322	PMP22	1
NM_001102396		1
NM_025073	SIKE	1
NM_014809	KIAA0319	1
NM_000961	PTGIS	1
XM_378312	LOC283143	1
XM_943773	LOC283143	1
NM_000544	TAP2	1
NM_003363	USP4	1
NM_199443	USP4	1
NM_003156	STIM1	1
NM_012064	MIP	1
NM_015993	PLLP	1
NM_182522	FAM19A4	1
NM_001005527	FAM19A4	1
XM_926071	LOC642592	1
NM_001099692		1
NM_001543	NDST1	1
NM_002035	FVT1	1
NM_001174	ARHGAP6	1
NM_014286	FREQ	1
NM_003942	RPS6KA4	1
NM_001006944	RPS6KA4	1
NM_006996	SLC19A2	1
NM_007011	ABHD2	1
NM_152924	ABHD2	1
NM_033129	SCRT2	1
NM_020127	TUFT1	1
NM_144682	SLFN13	1
NM_017586	C9orf7	1
NM_004087	DLG1	1
NM_001098424		1
NM_198461	LONRF2	1
NM_020700		1
NM_003982	SLC7A7	1
NM_006875	PIM2	1
NM_001042520	MGC13057	1
NM_001042521	MGC13057	1
NM_001042519	MGC13057	1
NM_032321	MGC13057	1
NM_016575	NT5DC3	1
NM_024523	GCC1	1
NM_001013659	ZNF793	1
NM_005497	GJA7	1
NM_001080383	GJA7	1
NM_001005176	SP140	1
NM_012175	FBXO3	1
XM_930224	LOC647190	1
XM_941815	LOC647190	1
NM_015257	KIAA0286	1
NM_012302	LPHN2	1
NM_016261	TUBD1	1
NM_001005747	CACNB4	1
NM_000726	CACNB4	1
NM_001005746	CACNB4	1
XM_378876	LOC149351	1
XM_943142	LOC149351	1
NM_032534	KRBA1	1
NM_020717	SHROOM4	1
NM_020921	NIN	1
NM_031284	ADPGK	1
NM_006269	RP1	1
NM_006926	SFTPA2	1
NM_001098668		1
NM_177977	HAP1	1
NM_003949	HAP1	1
NM_001079870	HAP1	1
NM_001079871	HAP1	1
NM_032173		1
NM_004748	CCPG1	1
NM_020739	CCPG1	1
NM_205846	PRELID2	1
NM_138492	PRELID2	1
NM_182960	PRELID2	1
NM_206809	MOG	1
NM_001008228	MOG	1
NM_206812	MOG	1
NM_207170	SYF2	1
NM_015484	SYF2	1
NM_016142	HSD17B12	1
NM_014840	NUAK1	1
NM_002187	IL12B	1
NM_013443	ST6GALNAC6	1
NM_001001389	CD44	1
NM_001001390	CD44	1
NM_001001391	CD44	1
NM_001001392	CD44	1
NM_000610	CD44	1
NM_018700	TRIM36	1
NM_012244	SLC7A8	1
NM_182728	SLC7A8	1
NM_001009984		1
NM_199459	C10orf71	1
XM_936719	LOC647662	1
NM_175080	P2RX5	1
NM_002561	P2RX5	1
NM_006920	SCN1A	1
NM_133482	RAD50	1
NM_005732	RAD50	1
NM_014743	KIAA0232	1
NM_001100590		1
NM_002880	RAF1	1
NM_031866	FZD8	1
NM_002898	RBMS2	1
NM_018469	TEX2	1
XM_039733	KIAA0953	1
XM_940464	KIAA0953	1
NM_012121	CDC42EP4	1
NM_015566		1
NM_001949	E2F3	1
NM_019064	SDK2	1
NM_004012	DMD	1
NM_004016	DMD	1
NM_004009	DMD	1
NM_004017	DMD	1
NM_000109	DMD	1
NM_004011	DMD	1
NM_004015	DMD	1
NM_004023	DMD	1
NM_004022	DMD	1
NM_004020	DMD	1
NM_004021	DMD	1
NM_004007	DMD	1
NM_004006	DMD	1
NM_004013	DMD	1
NM_004014	DMD	1
NM_004018	DMD	1
NM_004010	DMD	1
NM_002355	M6PR	1
NM_001002860	BTBD7	1
NM_032458	PHF6	1
NM_001015877	PHF6	1
NM_014952	BAHD1	1
NM_005124	NUP153	1
NM_152722	HEPACAM	1
NM_004119	FLT3	1
NM_001009899	KIAA2018	1
NM_006593	TBR1	1
NM_020960	GPR107	1
NM_198582	KLHL30	1
NM_133471		1
NM_015488	PNKD	1
NM_022572	PNKD	1
XM_932810	LOC645323	1
XM_943660	LOC645323	1
NM_000872	HTR7	1
NM_019859	HTR7	1
NM_019860	HTR7	1
NM_018210	FLJ10769	1
NM_177996	EPB41L1	1
NM_012156	EPB41L1	1
NM_000641	IL11	1
NM_001034852	SMOC1	1
NM_022137	SMOC1	1
NM_152677	ZSCAN4	1
NM_198836	ACACA	1
NM_198837	ACACA	1
NM_198834	ACACA	1
NM_198838	ACACA	1
NM_198839	ACACA	1
XM_373553	LOC387895	1
XM_945559	LOC387895	1
NM_001018050	POLR3H	1
NM_138338	POLR3H	1
NM_001018052	POLR3H	1
NM_173540	FUT11	1
NM_007137	ZNF81	1
NM_207446	LOC400451	1
NM_181656	C17orf58	1
NM_023078	PYCRL	1
NM_032865	TNS4	1
NM_024909	C6orf134	1
NM_004710	SYNGR2	1
XM_937698	LOC648629	1
NM_004925	AQP3	1
NM_173587	RCOR2	1
NM_000210	ITGA6	1
NM_001079818	ITGA6	1
NM_014663	JMJD2A	1
NM_005895	GOLGA3	1
NM_021200	PLEKHB1	1
XM_001129630	CCS	1
NM_001098531		1
NM_006105	RAPGEF3	1
NM_001098532		1
NM_005374	MPP2	1
NM_015717	CD207	1
NM_018121	C10orf6	1
NM_173641	EPHA10	1
NM_005910	MAPT	1
NM_016841	MAPT	1
NM_016834	MAPT	1
NM_016835	MAPT	1
NM_014584	ERO1L	1
NM_006040	HS3ST4	1
XM_001132212	HS3ST4	1
NM_001008693	CST9	1
NM_016339	RAPGEFL1	1
NM_017488	ADD2	1
NM_017483	ADD2	1
NM_001617	ADD2	1
NM_033012	TNFSF11	1
NM_003701	TNFSF11	1
NM_003629	PIK3R3	1
NM_030593	SIRT2	1
NM_012237	SIRT2	1
NM_012153	EHF	1
NM_152942	TNFRSF8	1
NM_001243	TNFRSF8	1
NM_005442	EOMES	1
NM_004469	FIGF	1
NM_018134	IQCC	1
NM_175862	CD86	1
NM_006889	CD86	1
NM_001039580	MAP9	1
NM_024674	LIN28	1
NM_014358	CLEC4E	1
NM_152375	KLHDC7A	1
NM_006540	NCOA2	1
NM_000397	CYBB	1
NM_020377	CYSLTR2	1
NM_006047	RBM12	1
NM_152838	RBM12	1
NM_003742	ABCB11	1
NM_000327	ROM1	1
NM_016257	HPCAL4	1
NM_013411	AK2	1
NM_020834	HOMEZ	1
NM_000629	IFNAR1	1
NM_018004	TMEM45A	1
NM_178314	FLJ39378	1
NM_001518	GTF2I	1
NM_032999	GTF2I	1
NM_033000	GTF2I	1
NM_033001	GTF2I	1
XM_001133646	LOC732437	1
NM_144718	CCDC52	1
NM_019116	UBFD1	1
NM_020190	OLFML3	1
NM_020883		1
NM_016820	OGG1	1
NM_002542	OGG1	1
NM_016819	OGG1	1
NM_032801	JAM3	1
NM_015471	NSL1	1
NM_001042549	NSL1	1
NM_004745	DLGAP2	1
NM_001010980	C1orf130	1
NM_016170	TLX2	1
XM_938207	LOC649125	1
NM_005722	ACTR2	1
NM_001005386	ACTR2	1
NM_018373	SYNJ2BP	1
NM_015247	CYLD	1
NM_001042412	CYLD	1
NM_001042355	CYLD	1
NM_183381	RNF13	1
NM_183384	RNF13	1
NM_007282	RNF13	1
NM_183383	RNF13	1
NM_001018103	GRINL1A	1
NM_000529	MC2R	1
NM_001003712	OSBPL8	1
NM_020841	OSBPL8	1
NM_001080410	FBXO41	1
XM_001133261	FBXO41	1
NM_000875	IGF1R	1
NM_001112663		1
NM_006629	ZNF271	1
NM_006601	PTGES3	1
XM_496721	LOC441050	1
XM_939520	LOC441050	1
NM_006620	HBS1L	1
NM_001802	CDR2	1
NM_030571	NDFIP1	1
NM_182493	MLCK	1
NM_001099220		1
NM_001080437	SNED1	1
XM_940984	SNED1	1
NM_002919	RFX3	1
NM_152758	YTHDF3	1
NM_001077350	C16orf35	1
NM_001039476	C16orf35	1
NM_006813	PNRC1	1
NM_033133	CNP	1
NM_004296	RGS6	1
NM_033468	ZNF257	1
NM_024707	GEMIN7	1
NM_001007270	GEMIN7	1
NM_001007269	GEMIN7	1
XM_939083	TTC28	1
XM_929318	TTC28	1
XM_943589	LOC647946	1
NM_015176	FBXO28	1
XM_001127362	KIAA0574	1
NM_013372	GREM1	1
NM_080415	SEPT4	1
NM_001032380	RHOBTB1	1
NM_198225	RHOBTB1	1
NM_014836	RHOBTB1	1
NM_020956	PRX	1
NM_133458	ZFP90	1
NM_178815	ARL5B	1
NM_001018036	TSHR	1
NM_025201	PLEKHQ1	1
NM_198486	RPL7L1	1
NM_002985	CCL5	1
NM_032374	C14orf153	1
NM_006197	PCM1	1
NM_007295	BRCA1	1
NM_007302	BRCA1	1
NM_007304	BRCA1	1
NM_007297	BRCA1	1
NM_007296	BRCA1	1
NM_007300	BRCA1	1
NM_007305	BRCA1	1
NM_007294	BRCA1	1
NM_007299	BRCA1	1
NM_007303	BRCA1	1
NM_007298	BRCA1	1
NM_006502	POLH	1
NM_001034841	LOC162073	1
NM_021030	ZNF14	1
NM_013313	YPEL1	1
NM_194451	LIAS	1
NM_006859	LIAS	1
NM_020917	ZFP14	1
NM_001104586		1
NM_024744	ALS2CR8	1
NM_000415	IAPP	1
NM_001033578	SGK3	1
NM_013257	SGK3	1
NM_170709	SGK3	1
NM_018068	PIWIL2	1
NM_001030010	ALDH3B1	1
NM_000694	ALDH3B1	1
NM_170710	WDR17	1
NM_181265	WDR17	1
XM_001130036	LOC730815	1
XM_001132008	LOC728769	1
NM_207320	OTUD6A	1
NM_001204	BMPR2	1
NM_000441	SLC26A4	1
NM_198445	FLJ45909	1
NM_152304	RAB42	1
NM_000379	XDH	1
XM_379623	FLJ41200	1
XM_943473	FLJ41200	1
NM_033481	FBXO9	1
NM_033480	FBXO9	1
NM_012347	FBXO9	1
NM_001099	ACPP	1
NM_133647	SLC12A6	1
NM_001042495	SLC12A6	1
NM_001042494	SLC12A6	1
NM_001042497	SLC12A6	1
NM_005135	SLC12A6	1
NM_001042496	SLC12A6	1
NM_024855	ACTR5	1
NM_020139	BDH2	1
NM_153689	FLJ38973	1
NM_000791	DHFR	1
NM_019001	XRN1	1
NM_001042604	XRN1	1
NM_033109	PNPT1	1
NM_009589	ARSD	1
NM_018420	SLC22A15	1
NM_016087	WNT16	1
NM_057168	WNT16	1
NM_001903	CTNNA1	1
NM_032294	CAMKK1	1
NM_172206	CAMKK1	1
NM_014911	AAK1	1
NM_006622	PLK2	1
NM_003617	RGS5	1
NM_016351	ADAM22	1
NM_021723	ADAM22	1
NM_021722	ADAM22	1
NM_012465	TLL2	1
NM_005128	DOPEY2	1
NM_016045	SLMO2	1
NM_020870	SH3RF1	1
NM_006544	EXOC5	1
NM_030578	MGC4093	1
NM_033240	PML	1
NM_033247	PML	1
NM_033239	PML	1
NM_033250	PML	1
NM_033244	PML	1
XM_930750	LOC642366	1
XM_943652	LOC642366	1
NM_001102470		1
NM_004741	NOLC1	1
NM_020962	NOPE	1
XM_001133285	TMEM151	1
NM_001030060	SAMD5	1
NM_014035	SNX24	1
NM_147196	TMIE	1
XM_943034	LOC643085	1
XM_931304	LOC643085	1
NM_052840	BRUNOL6	1
NM_006690	MMP24	1
NM_033439	IL33	1
NM_005149	TBX19	1
NM_006913	RNF5	1
NM_016518	PIPOX	1
NM_012134	LMOD1	1
NM_003559	PIP5K2B	1
NM_031958	KRTAP3-1	1
NM_004100	EYA4	1
NM_172105	EYA4	1
NM_172103	EYA4	1
NM_005915	MCM6	1
NM_001002926	TWISTNB	1
NM_173080	SPRR4	1
NM_016548	GOLPH2	1
NM_177937	GOLPH2	1
NM_004613	TGM2	1
NM_002531	NTSR1	1
NM_002084	GPX3	1
XM_001132013	ANKH	1
NM_031910	C1QTNF6	1
NM_182486	C1QTNF6	1
XM_933796	SLC45A4	1
XM_944850	SLC45A4	1
NM_001080431	SLC45A4	1
NM_001077691	ALG9	1
NM_001077692	ALG9	1
NM_024740	ALG9	1
NM_001077690	ALG9	1
NM_152988	SPPL2B	1
NM_001077238	SPPL2B	1
NM_006306	SMC1A	1
NM_133266	SHANK2	1
NM_020910		1
NM_174940	TMEM80	1
NM_001042463	TMEM80	1
NM_001042573	FLJ21865	1
NM_033446	FAM125B	1
NM_018319	TDP1	1
NM_001008744	TDP1	1
NM_015533	DAK	1
NM_031937	TBC1D10A	1
NM_003885	CDK5R1	1
XM_378661	C17orf51	1
XM_944416	C17orf51	1
NM_001098504		1
NM_030881	DDX17	1
NM_001098505		1
NM_006386	DDX17	1
NM_139283	PPTC7	1
NM_001040455	SIDT2	1
NM_001130	AES	1
NM_198970	AES	1
NM_198969	AES	1
NM_031444	C22orf13	1
NM_001102445		1
NM_005613	RGS4	1
NM_001113239		1
NM_022740	HIPK2	1
NM_031891	CDH20	1
NM_014393	STAU2	1
NM_018921	PCDHGA9	1
NM_018923	PCDHGB2	1
NM_018929	PCDHGC5	1
NM_002588	PCDHGC3	1
NM_018917	PCDHGA4	1
NM_018918	PCDHGA5	1
NM_032088	PCDHGA8	1
NM_018915	PCDHGA2	1
NM_018922	PCDHGB1	1
NM_003736	PCDHGB4	1
NM_018927	PCDHGB7	1
NM_018924	PCDHGB3	1
NM_018914	PCDHGA11	1
NM_018920	PCDHGA7	1
NM_018913	PCDHGA10	1
NM_018916	PCDHGA3	1
NM_018926	PCDHGB6	1
NM_003735	PCDHGA12	1
NM_032403	PCDHGC3	1
NM_032092	PCDHGA11	1
NM_018912	PCDHGA1	1
NM_018919	PCDHGA6	1
NM_018925	PCDHGB5	1
NM_018928	PCDHGC4	1
NM_003221	TFAP2B	1
NM_001098801		1
NM_152352	C18orf19	1
NM_005461	MAFB	1
NM_006771	KRT38	1
NM_173075	APBB2	1
NM_148912	ABHD11	1
NM_019008	SMCR7L	1
NM_033025	SYDE1	1
XM_370758	LOC387978	1
XM_940323	LOC387978	1
NM_014682	ST18	1
NM_138333	FAM122A	1
NM_020873	LRRN1	1
NM_022658	HOXC8	1
NM_015071	ARHGAP26	1
XM_209554	LOC285299	1
XM_936463	LOC285299	1
XM_936539	FLJ20518	1
XM_941245	LOC651959	1
NM_139265	EHD4	1
NM_032503	MCHR2	1
NM_001040179	MCHR2	1
NM_013435	RAX	1
NM_004059	CCBL1	1
NM_001003722	GLE1L	1
NM_024063	SPATA5L1	1
NM_015124	DIP	1
NM_014374	REPIN1	1
NM_001099696		1
NM_013400	REPIN1	1
NM_001099695		1
NM_001188	BAK1	1
NM_000252	MTM1	1
NM_000697	ALOX12	1
NM_005817	M6PRBP1	1
NM_020405	PLXDC1	1
NM_013318		1
NM_031469	SH3BGRL2	1
NM_080819	GPR78	1
NM_014817	KIAA0644	1
NM_194279	ISCA2	1
NM_174976	ZDHHC22	1
NM_005877	SF3A1	1
NM_001005409	SF3A1	1
NM_001725	BPI	1
NM_206914	FAM119B	1
NM_015433	FAM119B	1
NM_152372	MYOM3	1
NM_000296	PKD1	1
NM_001009944	PKD1	1
NM_152745	NXPH1	1
NM_001099784		1
NM_022060	ABHD4	1
NM_014819	PJA2	1
NM_005202	COL8A2	1
NM_020458	TTC7A	1
NM_178175	LHFPL1	1
XM_001129441	LOC645166	1
XM_946374	LSP1	1
NM_015111	N4BP3	1
NM_178520	TMEM105	1
NM_020940	KIAA1600	1
NM_001039709	CBFA2T2	1
NM_001032999	CBFA2T2	1
NM_005093	CBFA2T2	1
NM_013380	ZNF228	1
NM_001083335	ZNF228	1
NM_015264	C22orf9	1
NM_001009880	C22orf9	1
NM_007232	HRH3	1
NM_018132	CENPQ	1
NM_014423	AFF4	1
NM_170723	CDY1	1
NM_001003894	CDY1B	1
NM_012309	SHANK2	1
NM_001099691		1
NM_003236	TGFA	1
NM_001099626		1
NM_019557	FAM54B	1
NM_001099627		1
NM_001099625		1
NM_018697	LANCL2	1
NM_007144	PCGF2	1
XM_377073	LOC376475	1
NM_080475	SERPINB11	1
NM_016075	VPS36	1
NM_173557	RNF152	1
NM_025027	ZNF606	1
NM_001005365	POTE8	1
NM_001002920	POTE8	1
NM_080876	DUSP19	1
NM_152695	ZNF449	1
NM_080671	KCNE4	1
NM_005909	MAP1B	1
NM_015147	CEP68	1
NM_001040285	PAPD5	1
NM_001040284	PAPD5	1
NM_001037494	DYNLL1	1
NM_001037495	DYNLL1	1
NM_003746	DYNLL1	1
NM_018263	ASXL2	1
NM_006822	RAB40B	1
NM_001101676		1
NM_004432	ELAVL2	1
NM_001412	EIF1AX	1
NM_017592	IXL	1
NM_018684	KIAA1166	1
NM_015093	MAP3K7IP2	1
NM_015652	C10orf12	1
NM_207009	FAM45A	1
NM_006212	PFKFB2	1
NM_014023	WDR37	1
NM_206891	DIP2A	1
NM_020813	ZNF471	1
NM_001002800	SMC4	1
NM_005496	SMC4	1
NM_014964	EPN2	1
NM_001102664		1
NM_148921	EPN2	1
NM_178013	PRIMA1	1
NM_001024647	RAB3IP	1
NM_022456	RAB3IP	1
NM_175624	RAB3IP	1
NM_175625	RAB3IP	1
NM_175623	RAB3IP	1
NM_003088	FSCN1	1
NM_144683	DHRS13	1
NM_004055	CAPN5	1
NM_016089	ZNF589	1
NM_000486	AQP2	1
NM_001005463	EBF3	1
NM_021922	FANCE	1
NM_032111	MRPL14	1
NM_014353	RAB26	1
NM_012068	ATF5	1
NM_018689	KIAA1199	1
NM_002256	KISS1	1
NM_020925	CACHD1	1
NM_033102	SLC45A3	1
NM_032153	ZIC4	1
NM_170606	MLL3	1
NM_152835	PDIK1L	1
NM_133496	SLC30A7	1
NM_032214	SLA2	1
NM_175077	SLA2	1
NM_001018046	YSK4	1
NM_025052	YSK4	1
NM_014338	PISD	1
NM_147148	GSTM4	1
NM_005801	EIF1	1
NM_024922	CES3	1
NM_020807	ZNF319	1
NM_002730	PRKACA	1
NM_207518	PRKACA	1
XM_001124630	LOC730418	1
NM_145207	SPATA5	1
NM_207411	XKR5	1
NM_006187	OAS3	1
XM_941808	LOC399888	1
XM_374880	LOC399888	1
NM_080669	SLC46A1	1
NM_032859	ABHD13	1
NM_000681	ADRA2A	1
NM_001885	CRYAB	1
XM_001127482	LOC728445	1
NM_006572	GNA13	1
XM_001129280	LOC729086	1
XM_938287	LOC653930	1
NM_030796	ECOP	1
NM_005802	TOPORS	1
NM_198719	PTGER3	1
NM_181785	SLC46A3	1
NM_015657	ABCA12	1
NM_173076	ABCA12	1
NM_006486	FBLN1	1
XM_001130020	KIAA1147	1
XM_001130081	KIAA1147	1
NM_001080392	KIAA1147	1
NM_018662	DISC1	1
NM_001012957	DISC1	1
NM_000890	KCNJ5	1
NM_031890	CECR6	1
NM_153254	TTLL10	1
NM_000719	CACNA1C	1
NM_007286	SYNPO	1
NM_018275	C7orf43	1
NM_015299	KIAA0323	1
NM_015023	WDTC1	1
NM_022164	TINAGL1	1
NM_182579	C1orf157	1
NM_001031717	CRELD1	1
NM_006546	IGF2BP1	1
NM_152429	FGFBP3	1
NM_001099666		1
NM_020384	CLDN2	1
NM_031426	C9orf58	1
NM_004571	PKNOX1	1
NM_152424	FAM123B	1
NM_000525	KCNJ11	1
NM_012265	RHBDD3	1
NM_033656	BRWD1	1
NM_052880	PIK3IP1	1
NM_006464	TGOLN2	1
NM_001099278		1
NM_015374	UNC84B	1
NM_002264	KPNA1	1
NM_022845	CBFB	1
NM_001755	CBFB	1
NM_032817	ITIH5	1
NM_030569	ITIH5	1
NM_003528	HIST2H2BE	1
NM_004427	PHC2	1
NM_198040	PHC2	1
NM_052897	MBD6	1
NM_001077196	PDE11A	1
NM_001077197	PDE11A	1
NM_016953	PDE11A	1
NM_030788	TM7SF4	1
NM_022143	LRRC4	1
NM_012326	MAPRE3	1
NM_001103176		1
NM_001099413		1
NM_001099412		1
NM_006766	MYST3	1
NM_001039112	FER1L6	1
NM_007049	BTN2A1	1
NM_078476	BTN2A1	1
NM_005639	SYT1	1
NM_004273	CHST3	1
NM_182501	MTERFD2	1
NM_153367	C10orf56	1
NM_004051	BDH1	1
NM_203315	BDH1	1
NM_203314	BDH1	1
NM_003119	SPG7	1
NM_017436	A4GALT	1
NM_007347	AP4E1	1
NM_130809	PRRC1	1
NM_030806	C1orf21	1
XM_001126137	LOC284952	1
XM_001129340	LOC284952	1
NM_000674	ADORA1	1
NM_001048230	ADORA1	1
NM_178840	C1orf64	1
NM_032873	STS-1	1
NM_004127	GPS1	1
NM_212492	GPS1	1
NM_005746	PBEF1	1
NM_182894	CHX10	1
NM_012072	CD93	1
NM_002105	H2AFX	1
NM_016233	PADI3	1
NM_012170	FBXO22	1
NM_002334	LRP4	1
XM_938127	ZNF629	1
NM_001080417	ZNF629	1
NM_017924	C14orf119	1
NM_012458	TIMM13	1
NM_000084	CLCN5	1
NM_001381	DOK1	1
NM_001011718	XKR7	1
NM_001031694	SCMH1	1
NM_012236	SCMH1	1
NM_004782	SNAP29	1
NM_198389	PDPN	1
NM_006474	PDPN	1
NM_001006624	PDPN	1
NM_001006625	PDPN	1
NM_000192	TBX5	1
NM_080717	TBX5	1
NM_181486	TBX5	1
NM_173598	KSR2	1
NM_015687	FILIP1	1
NM_014767	SPOCK2	1
NM_001944	DSG3	1
NM_001101346		1
NM_032554	GPR81	1
NM_001040659	TTC23	1
NM_001040656	TTC23	1
NM_001040658	TTC23	1
NM_022905	TTC23	1
NM_001040657	TTC23	1
NM_001040655	TTC23	1
NM_001040660	TTC23	1
NM_001024660	KALRN	1
NM_007064	KALRN	1
NM_002428	MMP15	1
NM_003564	TAGLN2	1
NM_001001561	GGA1	1
NM_005759	ABI2	1
XM_001126750	ABI2	1
NM_001045478	LOC644997	1
NM_001015887	IGSF11	1
NM_152538	IGSF11	1
NM_012250	RRAS2	1
NM_001102669		1
NM_001012339	DNAJA5	1
NM_194283	DNAJA5	1
NM_003575	ZNF282	1
NM_020999	NEUROG3	1
NM_005440	RND2	1
NM_144641	PPM1M	1
NM_183240	TMEM37	1
NM_152903	KBTBD6	1
NM_207417	FLJ46082	1
NM_018306	TMEM40	1
NM_007047	BTN3A2	1
NM_005270	GLI2	1
NM_138554	TLR4	1
NM_203350	ZRANB2	1
NM_005455	ZRANB2	1
NM_020911		1
NM_001105079		1
NM_015266	SLC9A8	1
NM_020705	TBC1D24	1
NM_007182	RASSF1	1
NM_170714	RASSF1	1
NM_170712	RASSF1	1
NM_170713	RASSF1	1
NM_138348	FAM105B	1
NM_002417	MKI67	1
NM_001083591	CUGBP2	1
NM_001025077	CUGBP2	1
NM_006561	CUGBP2	1
NM_001025076	CUGBP2	1
XM_001128452	LOC728777	1
XM_001128728	LOC731178	1
NM_207360		1
NM_199050	C21orf25	1
NM_015500	C21orf25	1
XM_032945	C21orf25	1
NM_001496	GFRA3	1
NM_181501	ITGA1	1
NM_001010883	FAM102B	1
NM_006888	CALM1	1
NM_015042	ZNF609	1
NM_012288	TRAM2	1
NM_003590	CUL3	1
NM_016327	UPB1	1
NM_020713	ZNF512B	1
NM_001017396	ZNF2	1
NM_021088	ZNF2	1
NM_175911	OR2L13	1
NM_003557	PIP5K1A	1
NM_001011513	PDLIM5	1
NM_006457	PDLIM5	1
NM_013262	MYLIP	1
NM_004293	GDA	1
NM_007073	BVES	1
NM_147147	BVES	1
NM_001003652	SMAD2	1
NM_005901	SMAD2	1
NM_001614	ACTG1	1
NM_030938	TMEM49	1
NM_017769	KIAA1333	1
NM_004071	CLK1	1
NM_022463	NXN	1
NM_017637	BNC2	1
NM_022906		1
NM_134431	SLCO1A2	1
NM_005195	CEBPD	1
NM_004230	EDG5	1
NM_017552		1
NM_018941	CLN8	1
NM_198529	EFCAB5	1
NM_001008487	SLC41A3	1
NM_017836	SLC41A3	1
NM_014046	MRPS18B	1
NM_001167	BIRC4	1
NM_020831	MKL1	1
NM_017991	FLJ10081	1
NM_001034	RRM2	1
NM_133646	ZAK	1
NM_015187	KIAA0746	1
NM_152404	UGT3A1	1
NM_138400	NOM1	1
NM_206963	RARRES1	1
NM_030784	GPR63	1
NM_024512	LRRC2	1
NM_020766	PCDH19	1
NM_001105243		1
NM_018193	KIAA1794	1
NM_002357	MXD1	1
NM_005369	MCF2	1
NM_001099855		1
NM_018945	PDE7B	1
NM_002211	ITGB1	1
NM_032317	WBSCR18	1
NM_080725	SRXN1	1
NM_000337	SGCD	1
NM_004857	AKAP5	1
NM_001659	ARF3	1
NM_058169	LOH12CR1	1
NM_014761	KIAA0174	1
NM_138969	RDHE2	1
NM_001040445	ASB1	1
NM_001031679	MSRB3	1
NM_198080	MSRB3	1
NM_005665	EVI5	1
NM_173569		1
NM_031945	TSPAN10	1
NM_144967	FLJ30058	1
NM_003909	CPNE3	1
NM_182744	NBL1	1
NM_005380	NBL1	1
NM_016173	HEMK1	1
NM_012455	PSD4	1
NM_001039840	CHIC1	1
NM_005795	CALCRL	1
NM_001004341	FLJ16478	1
NM_144982	CCDC131	1
NM_001100421		1
NM_001100420		1
NM_017447	C21orf91	1
NM_015644	TTLL3	1
NM_000429	MAT1A	1
NM_006617	NES	1
NM_152660	FAM76A	1
NM_014007	ZBTB43	1
NM_144676	TMED6	1
NM_014347	ZNF324	1
NM_152916	EMR2	1
NM_152918	EMR2	1
NM_152917	EMR2	1
NM_152920	EMR2	1
NM_152921	EMR2	1
NM_013447	EMR2	1
NM_152919	EMR2	1
NM_002747	MAPK4	1
NM_002560	P2RX4	1
NM_001018090	Gcom1	1
NM_001018102	GRINL1A	1
NM_015532	GRINL1A	1
NM_001018091	Gcom1	1
XM_943391	LOC339970	1
XM_291095	LOC339970	1
NM_002395	ME1	1
NM_182705	FAM101B	1
XM_001126665	FAM101B	1
XM_937862	LOC644962	1
NM_014655	SLC25A44	1
NM_181877	ZSCAN2	1
NM_007271	STK38	1
NM_139056	ADAMTS16	1
NM_182920	ADAMTS9	1
NM_012166	FBXO10	1
NM_024577	SH3TC2	1
NM_138417	KTI12	1
NM_020795	NLGN2	1
XM_941807	NHSL1	1
XM_496826	NHSL1	1
NM_002092	GRSF1	1
NM_001098477		1
NM_001039803	CCRK	1
NM_178432	CCRK	1
NM_012119	CCRK	1
NM_017803	DUS2L	1
NM_004774	PPARBP	1
NM_031435	THAP2	1
NM_021116	ADCY1	1
NM_017621	ALKBH4	1
NM_001001479	SLC35E4	1
NM_001669	ARSD	1
XM_209227	LOC653464	1
NM_001109689		1
NM_021061	ZNF250	1
NM_014722		1
NM_017708	FAM83E	1
NM_001011655	TMEM44	1
NM_138399	TMEM44	1
NM_001098498		1
NM_001098497		1
NM_001039948	RUTBC2	1
NM_133454	RUTBC2	1
NM_052928	SMYD4	1
NM_001013624	LOC201181	1
NM_004798	KIF3B	1
NM_001736	C5AR1	1
NM_033130	SIGLEC10	1
NM_006245	PPP2R5D	1
NM_180976	PPP2R5D	1
NM_180977	PPP2R5D	1
NM_001535	PRMT2	1
NM_206962	PRMT2	1
NM_018660	ZNF395	1
NM_020117	LARS	1
NM_014268	MAPRE2	1
NM_001712	CEACAM1	1
NM_001024912	CEACAM1	1
NM_012331	MSRA	1
NM_152744	SDK1	1
NM_031215	CABLES2	1
NM_004727	SLC24A1	1
XM_945019	LOC643441	1
XM_933124	LOC643441	1
NM_033407	DOCK7	1
NM_016301	ATPBD1C	1
NM_016124	RHD	1
NM_005095	ZMYM4	1
NM_001024596	ZNF772	1
NM_017886		1
NM_014763	MRPL19	1
NM_020345	NKIRAS1	1
NM_212461	PRKAG1	1
NM_002733	PRKAG1	1
NM_025152	NUBPL	1
NM_032012	C9orf5	1
NM_001099734		1
NM_006933	SLC5A3	1
NM_152623	CDC20B	1
NM_182832	PLAC4	1
NM_001427	EN2	1
NM_198281	GPRIN3	1
NM_007057	ZWINT	1
NM_032997	ZWINT	1
NM_001005413	ZWINT	1
NM_015245	ANKS1A	1
NM_003708	RDH16	1
NM_030640	DUSP16	1
NM_015051	TXNDC4	1
NM_020242	KIF15	1
NM_004004	GJB2	1
NM_001277	CHKA	1
NM_212469	CHKA	1
NM_019096	GTPBP2	1
NM_003913	PRPF4B	1
NM_145251	STYX	1
XM_001125680	LOC730432	1
XM_001125705	LOC730432	1
NM_003099	SNX1	1
NM_152826	SNX1	1
NM_148955	SNX1	1
NM_001013655	LOC389834	1
NM_020382	SETD8	1
NM_006549	CAMKK2	1
NM_153499	CAMKK2	1
NM_153500	CAMKK2	1
NM_172216	CAMKK2	1
NM_172226	CAMKK2	1
NM_001077700	MIER1	1
NM_001077701	MIER1	1
NM_020948	MIER1	1

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Immunostimulatory motif search results

UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).

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Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

Parameter	Spec. Score cut-off	Colour	Comment
Hit to same gene		Colour	Hits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit	≥80	Colour	Hits are very likely to cause an off-target effect
Medium scoring hit	<80¸≥40	Colour	Hits with a small chance of causing an off target effect.
Low scoring hit		Colour	Hits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-off	Colour
Match	Colour
Wobble base pairs (G-U)	Colour
Critical bases (none)	Colour
0.6 bits	Colour
0.4 bits	Colour
0.2 bits	Colour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer

For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317