Predicted Off-targets for siRNA "gggagcauugacacaugugca" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

9 hits were found for GAGCAUUGACACAUGUGCA (2 guide strand hits and 7 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_002526 NT5E 2645 2663 GAGCAUUuACACAUGUuaA11 3 8 c false   <90%   3547
NM_152630 FAM46D 877 895 aAGCAaUGACACAUuUGCA9 3 8 c false   <90%   3027


Hits to Sense strand








AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_000328 RPGR 404 422 ccaACAUGUGUCAAaGCUC42 4 11 c false   <90%   3082
NM_001034853 RPGR 404 422 ccaACAUGUGUCAAaGCUC42 4 11 c false   <90%   4718
NM_018046 AGGF1 3490 3508 gGCACAgGUGUCAcUGCUC12 3 6 c false   <90%   4480
XM_940609 FLJ25076 3707 3725 cGCACAUGUGcCAAUaCUC10 3 9 c false   <90%   4305
XM_059689 FLJ25076 3821 3839 cGCACAUGUGcCAAUaCUC10 3 9 c false   <90%   4419
XM_045911 STXBP5L 3900 3918 UGCACAUGaGUuAAUGCUg1 3 8   false   <90%   5179
XM_938898 STXBP5L 3900 3918 UGCACAUGaGUuAAUGCUg1 3 8   false   <90%   5179


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1709
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_004992MECP24
NM_145176SLC2A123
NM_153456HS6ST33
NM_003966SEMA5A3
NM_173832ZFP413
NM_033656BRWD13
NM_0011016763
NM_024947PHC33
NM_016052RRP153
NM_020699GATAD2B3
NM_014423AFF43
NM_005596NFIB3
NM_018440PAG13
NM_153810C10orf463
NM_0011023963
NM_025073SIKE3
NM_006529GLRA32
NM_001042543GLRA32
NM_002398MEIS12
NM_014765TOMM202
NM_024770METTL82
NM_020313CIAPIN12
NM_001106ACVR2B2
NM_001010862SPIN32
NM_181654CPLX42
NM_030806C1orf212
NM_001455FOXO3A2
NM_201559FOXO3A2
NM_001024660KALRN2
NM_007064KALRN2
NM_030650KIAA17152
NM_014897ZNF6522
NM_005504BCAT12
NM_000230LEP2
NM_015565ZNF2942
NM_004171SLC1A22
NM_005546ITK2
NM_1735692
NM_014331SLC7A112
NM_000031ALAD2
NM_001003945ALAD2
NM_031912SYT152
NM_005595NFIA2
NM_052909KIAA19092
NM_002526NT5E2
NM_0010986142
NM_031292PUS7L2
NM_0010986152
NM_015000STK38L2
NM_001001685FLJ450792
NM_022826MARCH72
NM_006750SNTB22
NM_001032380RHOBTB12
NM_198225RHOBTB12
NM_014836RHOBTB12
NM_020453ATP10D2
NM_015365AMMECR12
NM_001025580AMMECR12
NM_014924KIAA08312
NM_021977SLC22A32
NM_152754SEMA3D2
NM_018970GPR852
NM_005741ZNF2632
NM_152263TPM32
NM_016308CMPK2
NM_003909CPNE32
NM_001040715LOC6533192
NM_014930ZNF5102
NM_025195TRIB12
NM_024512LRRC22
NM_005105RBM8A2
NM_152280SYT112
NM_001009993LOC1300742
NM_0330262
NM_014911AAK12
XM_001134215PDPR2
NM_145203CSNK1A1L2
NM_194285SPTY2D12
NM_020120UGCGL12
NM_001025777UGCGL12
NM_153645NUP502
NM_007172NUP502
NM_0011004252
NM_015314KIAA08952
NM_001005502CPM2
NM_198320CPM2
NM_001874CPM2
NM_021912GABRB32
NM_000814GABRB32
NM_138959VANGL12
NM_016269LEF12
NM_024769ASAM2
NM_0209102
NM_001005609EDA2
NM_001399EDA2
NM_003200TCF32
NM_021961TEAD12
NM_053282SH2D1B2
XM_001133830LOC7295192
XM_001134313LOC7322912
NM_012279ZNF3462
NM_003413ZIC32
NM_0010986382
XM_943454LOC6465882
XM_935989LOC6465882
XM_933738LOC6465882
NM_0010987212
NM_0010987222
NM_004485GNG42
NM_019063EML42
NM_005513GTF2E12
NM_0010400612
NM_001419ELAVL12
NM_024761MOBKL2B2
NM_000579CCR52
NM_0011001682
NM_0011055362
NM_020208SLC6A202
NM_022405SLC6A202
NM_032458PHF62
NM_001015877PHF62
NM_020774MIB12
NM_001040105MUC172
NM_001008408RBM332
NM_053043PRR82
NM_152624DCP22
NM_001009554MFAP3L2
NM_021647MFAP3L2
XM_001132925DUSP222
NM_016184CLEC4A2
NM_194450CLEC4A2
NM_194447CLEC4A2
NM_194448CLEC4A2
NM_198686RAB152
NM_001128AP1G12
NM_001030007AP1G12
NM_001497B4GALT12
NM_005226EDG32
NM_005086SSPN2
NM_030647JHDM1D2
NM_173475DCUN1D32
NM_001776ENTPD12
NM_0010981752
NM_019857CTPS22
NM_175859CTPS22
NM_001003793RBMS31
NM_001003792RBMS31
NM_032147USP441
NM_001042403USP441
NM_033254BOC1
NM_012334MYO101
NM_005759ABI21
XM_001126750ABI21
NM_020673RAB22A1
XM_170840LOC2562231
XM_932309LOC6446941
NM_014316CARHSP11
NM_001042476CARHSP11
XM_932949RGNEF1
NM_207318CXorf391
NM_007344TTF11
NM_020314MGC168241
NM_014550CARD101
NM_032047B3GNT51
NM_032943SYTL21
NM_206929SYTL21
NM_206930SYTL21
NM_206927SYTL21
NM_032379SYTL21
NM_206928SYTL21
NM_014830ZBTB391
NM_020857VPS181
NM_032145FBXO301
NM_001077706LFDH1
NM_016210C3orf181
NM_001012427FOXP41
NM_138457FOXP41
NM_001012426FOXP41
NM_015265SATB21
NM_020348CNNM11
NM_001029999MGC267181
NM_002446MAP3K101
NM_015084MRPS271
NM_001772CD331
NM_001082618CD331
NM_015578LSM14A1
NM_015508TIPARP1
NM_001080416MYBL11
NM_022064RNF1231
NM_001001995GPM6B1
NM_005587MEF2A1
NM_014464TINAG1
NM_005158ABL21
NM_007314ABL21
NM_0011001081
NM_145102ZKSCAN51
NM_014569ZKSCAN51
NM_212471PRKAR1A1
NM_212472PRKAR1A1
NM_002734PRKAR1A1
NM_001319CSNK1G21
NM_018509LRRC591
NM_030809FAM130A11
NM_014285EXOSC21
NM_004427PHC21
NM_198040PHC21
NM_014647KIAA04301
NM_000875IGF1R1
NM_014937INPP5F1
NM_015052HECW11
NM_181552CUTL11
NM_012257HBP11
NM_015891CDC401
NM_052932TMEM1231
NM_173598KSR21
NM_001554CYR611
NM_033132ZIC51
NM_006113VAV31
NM_001079874VAV31
NM_173647RNF1491
NM_0010982721
NM_002130HMGCS11
NM_148571MRPL271
NM_015257KIAA02861
NM_015358MORC31
NM_145259ACVR1C1
NM_0011110311
NM_0011110331
NM_0011110321
NM_015542UPF21
NM_080599UPF21
NM_018361AGPAT51
NM_017629EIF2C41
NM_130388ASB121
NM_020205OTUD7B1
XM_937430LOC6483771
XM_929253LOC6463161
NM_024917CXorf341
NM_173565LOC2229671
XM_001127690LOC7303031
NM_0010996971
NM_148964CTSE1
NM_001910CTSE1
XM_379623FLJ412001
XM_943473FLJ412001
NM_153332THEX11
NM_020922WNK31
NM_001002838WNK31
NM_001032394GPR1261
NM_020455GPR1261
NM_198569GPR1261
NM_001032395GPR1261
NM_001001394HCG31
NM_032553GPR1741
NM_001039395C9orf681
NM_018023YEATS21
NM_002402MEST1
NM_177524MEST1
NM_177525MEST1
NM_000950PRRG11
NM_012309SHANK21
NM_007368RASA31
NM_017523XAF11
NM_199139XAF11
NM_006037HDAC41
XM_166659OTUD11
XM_001134465OTUD11
XM_942776SYNPO21
XM_936336SYNPO21
XM_001131068LOC7296961
XM_001129643LOC7314351
NM_133477SYNPO21
NM_148170CTSC1
NM_173826C3orf231
NM_016265ZNF121
NM_006956ZNF121
NM_018092NETO21
NM_005329HAS31
NM_014321ORC6L1
NM_133493CD1091
NM_152437ZNF6641
NM_024900PHF171
NM_022735ACBD31
NM_005019PDE1A1
NM_006924SFRS11
NM_001078166SFRS11
NM_005099ADAMTS41
NM_004028AQP41
NM_001650AQP41
NM_153369KIAA19191
NM_002760PRKY1
NM_001005463EBF31
NM_012204GTF3C41
NM_020772NUFIP21
NM_001003698RREB11
NM_001003699RREB11
NM_002955RREB11
NM_032049AGTR11
NM_031850AGTR11
NM_004835AGTR11
NM_000685AGTR11
NM_009585AGTR11
NM_020761KIAA13031
NM_014747RIMS31
NM_015455CNOT61
NM_001018065NTRK21
NM_001018066NTRK21
NM_020113ACRV11
NM_020115ACRV11
NM_020108ACRV11
NM_020111ACRV11
NM_020107ACRV11
NM_020109ACRV11
NM_020069ACRV11
NM_020110ACRV11
NM_001612ACRV11
NM_007202AKAP101
NM_001127AP1B11
NM_145730AP1B11
XM_941733LOC6471151
XM_930136LOC6471151
NM_004731SLC16A71
NM_017975ZWILCH1
XM_929496LOC6465611
XM_937933LOC6465611
NM_014021SSX2IP1
NM_020676ABHD61
NM_198334GANAB1
NM_198335GANAB1
NM_001001709FLJ455371
NM_006054RTN31
NM_201429RTN31
NM_201428RTN31
NM_201430RTN31
NM_0175521
NM_005554KRT6A1
NM_173086KRT6C1
XM_380092LOC2859411
XM_379477LOC2859411
XM_938991LOC2859411
NM_001008539SLC7A21
NM_003046SLC7A21
NM_032679ZNF5771
NM_006557DMRT21
NM_181872DMRT21
NM_024561NARG1L1
NM_018317TBC1D191
NM_152594SPRED11
NM_080618CTCFL1
NM_017987RUFY21
NM_022739SMURF21
NM_198485FAM79B1
NM_000809GABRA41
NM_024019NEUROG21
NM_153714C10orf671
NM_006352ZNF2381
NM_205768ZNF2381
NM_002959SORT11
NM_144721THAP61
NM_0011024211
NM_0011024201
NM_006007ZFAND51
NM_033198PIGS1
NM_024989PGAP11
NM_001682ATP2B11
NM_001001323ATP2B11
NM_012329MMD1
NM_007146VEZF11
XM_001133802LOC7294641
NM_016520C9orf781
NM_152709STOX11
NM_203451LOC4001201
NM_002099GYPA1
NM_024645ZMAT41
NM_006298ZNF1921
NM_005095ZMYM41
NM_020546ADCY21
NM_016078FAM18B1
NM_133633SYN31
NM_003490SYN31
NM_001025079CD471
NM_001777CD471
NM_198793CD471
NM_173531ZNF1001
XM_938440LOC4006821
NM_001080975REPS21
NM_004726REPS21
NM_003036SKI1
NM_022100MRPS141
XM_001127437LOC7308391
NM_001009931HRNR1
NM_000921PDE3A1
NM_198468C6orf1671
NM_007347AP4E11
NM_198279CXorf231
NM_152622MIER31
NM_080760DACH11
NM_080759DACH11
NM_004392DACH11
NM_004685MTMR61
NM_031457MS4A8B1
NM_031953SNX251
NM_025054VCPIP11
NM_004898CLOCK1
NM_172071RC3H11
NM_205852CLEC12B1
NM_207411XKR51
NM_017418DEC11
NM_152305KTELC11
NM_012320LYPLA31
NM_006868RAB311
NM_001040665STEAP21
NM_152999STEAP21
NM_015554GLCE1
NM_005551KLK21
NM_001002231KLK21
NM_017852NLRP21
NM_015173TBC1D11
NM_144693ZNF5581
NM_198490RAB431
NM_018466ALG131
NM_194286KIAA18531
XM_001125875LOC7278181
NM_014686KIAA03551
NM_213594RFX41
NM_032491RFX41
NM_0207221
NM_015332NUDCD31
NM_000354SERPINA71
NM_003804RIPK11
NM_199454PRDM161
NM_022114PRDM161
NM_003119SPG71
NM_014286FREQ1
NM_153252BRWD31
NM_002565P2RY41
NM_024666FLJ115061
NM_033505SELI1
NM_001008494ISX1
NM_014817KIAA06441
NM_001033551TOM1L21
NM_001082968TOM1L21
NM_000800FGF11
NM_033137FGF11
NM_033136FGF11
NM_139201GIT21
NM_080742B3GAT21
NM_139125MASP11
NM_001987ETV61
NM_030571NDFIP11
NM_000128F111
NM_004462FDFT11
NM_018424EPB41L4B1
NM_025194ITPKC1
NM_001259CDK61
XM_943731LOC6494811
XM_932234LOC6445411
NM_138804LOC1309511
NM_016218POLK1
NM_001080463DYNC2H11
XM_931085DYNC2H11
XM_937807DYNC2H11
NM_152484ZNF5691
NM_138638CFL21
NM_021914CFL21
NM_001009909LUZP21
NM_015072TTLL51
NM_014211GABRP1
NM_016376ANKFY11
NM_000276OCRL1
NM_001587OCRL1
NM_173801PLAC1L1
NM_032786ZC3H101
NM_175569XG1
NM_024943TMEM1561
NM_032538TTBK11
NM_173536GABRG11
NM_016162ING41
NM_006482DYRK21
NM_003583DYRK21
NM_006885ATBF11
NM_183413FBXO441
NM_033182FBXO441
NM_001014765FBXO441
NM_183412FBXO441
NM_032153ZIC41
NM_174937TCERG1L1
NM_031431COG31
NM_207373C10orf991
NM_018184ARL8B1
NM_052880PIK3IP11
XM_927661LOC6445381
XM_939025LOC6445381
NM_0010992941
XM_936510KIAA16441
NM_024627C22orf291
XM_928075LOC6432871
XM_932585LOC6432871
XM_941283LOC6432871
XM_945078LOC6432871
NM_0010992851
NM_002823PTMA1
NM_004735LRRFIP11
NM_006636MTHFD21
NM_001040409MTHFD21
NM_014956CEP1641
XM_001129290STARD91
XM_001129482STARD91
NM_0010992701
NM_152735ZBTB91
NM_022474MPP51
NM_0148311
XM_001132359LOC7300911
XM_001132046LOC7321641
NM_016412IGF2AS1
NM_020373TMEM16B1
NM_054110GALNTL21
NM_181724TMEM1191
NM_032846RAB2B1
NM_052907TMEM132B1
NM_013363PCOLCE21
NM_198445FLJ459091
XM_001133778LOC7317101
NM_005140CNGA21
NM_006947SRP721
NM_021138TRAF21
NM_015641TES1
NM_152829TES1
NM_006965ZNF241
NM_024815NUDT181
NM_024565CCNJL1
NM_001918DBT1
NM_0151771
NM_000411HLCS1
NM_025191EDEM31
NM_182679GPATCH41
NM_015590GPATCH41
NM_001080415SR1401
XM_940802SR1401
NM_019044CCDC931
NM_013322SNX101
NM_013449BAZ2A1
NM_016544RBJ1
NM_001081491NXF11
NM_018302C4orf191
NM_0011046291
NM_000944PPP3CA1
NM_053042KIAA17291
XM_001129295LOC7287311
NM_178169RASSF31
NM_182507KRT801
NM_001081492KRT801
NM_001008860NIPA21
NM_001008894NIPA21
NM_001008892NIPA21
NM_030922NIPA21
NM_203327SLC23A21
NM_005116SLC23A21
NM_001029839C3orf231
NM_001029840C3orf231
XM_928866LOC6458951
XM_938922LOC6458951
NM_003286TOP11
NM_006237POU4F11
NM_178830C19orf471
NM_015150RFTN11
NM_018176LGI21
NM_024701ASB131
NM_003108SOX111
NM_001754RUNX11
NM_001001890RUNX11
NM_005336HDLBP1
NM_203346HDLBP1
NM_0251851
NM_0010988011
NM_152352C18orf191
NM_207459FLJ357671
NM_018045BSDC11
NM_182503DEADC11
NM_024408NOTCH21
XM_001133349NOTCH21
NM_153034ZNF4881
NM_017437CPSF21
NM_001024847TGFBR21
NM_003242TGFBR21
NM_0010996661
NM_139032MAPK71
NM_002749MAPK71
NM_139033MAPK71
NM_139034MAPK71
NM_203341SEP151
NM_004447EPS81
NM_173167UNC45B1
NM_001033576UNC45B1
NM_001663ARF61
NM_002218ITIH41
NM_004612TGFBR11
NM_015299KIAA03231
NM_032572RNASE71
NM_014872ZBTB51
NM_015957APIP1
NM_181435C1QTNF31
NM_030945C1QTNF31
NM_001558IL10RA1
NM_001040107HVCN11
NM_032369HVCN11
XM_927284DKFZP781G01191
XM_936878DKFZP781G01191
NM_001001436LOC3882721
NM_014702KIAA04081
XM_001129888KATNAL21
NM_003042SLC6A11
NM_000724CACNB21
NM_201596CACNB21
NM_201571CACNB21
NM_201593CACNB21
NM_201590CACNB21
NM_201572CACNB21
NM_201597CACNB21
NM_201570CACNB21
NM_198337INSIG11
NM_005542INSIG11
NM_198336INSIG11
NM_0153721
NM_006408AGR21
NM_000674ADORA11
NM_001048230ADORA11
NM_020773TBC1D141
NM_001629ALOX5AP1
NM_004200SYT71
XM_943686SYT71
NM_017990PDPR1
NM_024795TM4SF201
XM_001129849LOC7282491
NM_0152581
NM_183065TMEM1071
NM_032354TMEM1071
NM_003179SYP1
NM_001018108SERF21
NM_0133181
NM_001796CDH81
NM_033100PCDH211
NM_001008537KIAA20221
NM_198935SS18L11
NM_007078LDB31
NM_001080114LDB31
NM_198484ZNF6211
NM_0010984141
NM_001004106GRK61
NM_002082GRK61
NM_020742NLGN4X1
NM_181332NLGN4X1
NM_014893NLGN4Y1
NM_022845CBFB1
NM_001755CBFB1
NM_012316KPNA61
NM_002357MXD11
NM_001010903DKFZp779B15401
NM_001004301ZNF8131
NM_015090NFASC1
NM_001152SLC25A51
NM_015394ZNF101
NM_207333ZNF3201
XM_001132109LOC7300201
NM_001969EIF51
NM_183004EIF51
NM_000351STS1
NM_152682RWDD4A1
NM_007249KLF121
NM_001039547GK51
NM_138621BCL2L111
NM_006538BCL2L111
NM_052904KLHL321
NM_005638SYBL11
NM_138285NUP351
NM_152756RICTOR1
NM_182767SLC6A151
NM_004772C5orf131
NM_012234RYBP1
NM_033544RCCD11
NM_001017919RCCD11
XM_001132703FLJ410471
XM_001133280FLJ410471
NM_024593EFCAB11
NM_0151881
NM_032873STS-11
NM_052918SORCS11
NM_001013031SORCS11
NM_006353HMGN41
NM_145017C11orf661
NM_003890FCGBP1
XM_001131379FCGBP1
NM_000081LYST1
NM_0010937721
NM_000222KIT1
NM_172388NFATC11
NM_006162NFATC11
NM_172389NFATC11
NM_172387NFATC11
NM_001079685KIAA11911
NM_020444KIAA11911
NM_001079684KIAA11911
NM_021629GNB41
NM_014153ZC3H7A1
NM_138417KTI121
XM_927712LOC4401041
NM_022755IPPK1
NM_138723BCL2L141
NM_030766BCL2L141
NM_138722BCL2L141
XM_375443LOC2841001
NM_014952BAHD11
NM_007011ABHD21
NM_152924ABHD21
NM_002062GLP1R1
NM_020125SLAMF81
NM_004586RPS6KA31
NM_198399ARPP-211
NM_001025069ARPP-211
NM_001025068ARPP-211
NM_015991C1QA1
NM_032013NDRG31
NM_022477NDRG31
NM_016151TAOK21
NM_004293GDA1
NM_007175ERLIN21
NM_0010996451
NM_018362LIN7C1
NM_001037293PALM21
NM_053016PALM21
NM_002799PSMB71
NM_014618DBC11
NM_0024581
NM_018135MRPS18A1
NM_003496TRRAP1
NM_003503CDC71
NM_016019LUC7L21
NM_004119FLT31
NM_012214MGAT4A1
NM_005227EFNA41
NM_172239REXO1L11
NM_020132AGPAT31
NM_001037553AGPAT31
NM_006108SPON11
NM_145284FAM122B1
NM_173831ZNF7071
NM_0011005981
NM_0011005991
NM_015050KIAA00821
NM_005283XCR11
NM_001024644XCR11
NM_016598ZDHHC31
NM_178554KY1
NM_013358PADI11
NM_006464TGOLN21
NM_015155LARP51
NM_021905GABBR11
NM_001004341FLJ164781
NM_0011102201
NM_0011102211
NM_006783GJB61
NM_0011102191
NM_0010129941
NM_018073TRIM681
NM_016577RAB6B1
NM_001039591USP9X1
NM_001039590USP9X1
NM_198920C6orf1571
NM_005271GLUD11
XM_942780SYNPO21
NM_015144ZCCHC141
NM_152371C1orf931
NM_005688ABCC51
NM_004311ARL31
NM_005161AGTRL11
NM_018698NXT21
NM_013255MKLN11
NM_017994C7orf421
NM_0011031471
NM_0011031481
NM_0011031461
NM_015575TNRC151
NM_001003940BMF1
NM_001003943BMF1
NM_001003942BMF1
NM_033503BMF1
XM_373926LOC3888141
XM_944616LOC3888141
NM_020981B3GALT11
NM_004275TRFP1
NM_020795NLGN21
NM_213589RAPH11
NM_133367PAQR81
NM_144723ZMAT21
NM_020927KIAA15761
NM_1736011
NM_0010996501
NM_203459CAMSAP1L11
NM_018717MAML31
NM_017556FBLIM11
NM_001024216FBLIM11
NM_007114TMF11
NM_017676ZH2C21
XM_940069PPP1R3E1
XM_927029PPP1R3E1
NM_005822DSCR1L11
NM_0216231
NM_152916EMR21
NM_152918EMR21
NM_152917EMR21
NM_152920EMR21
NM_152921EMR21
NM_013447EMR21
NM_152919EMR21
NM_134325SLC26A91
NM_052934SLC26A91
NM_004985KRAS1
NM_033360KRAS1
NM_000319PEX51
NM_032107L3MBTL1
NM_015478L3MBTL1
NM_175709CBX71
NM_003101SOAT11
NM_031372HNRPDL1
NM_005828WDR681
NM_003044SLC6A121
NM_006056NMUR11
NM_0011046471
NM_018155SLC25A361
NM_0142471
NM_152464C17orf321
NM_004349RUNX1T11
NM_175634RUNX1T11
NM_175635RUNX1T11
NM_175636RUNX1T11
NM_004730ETF11
NM_133334WHSC11
NM_001037165FOXK11
NM_005750C4orf61
NM_005647TBL1X1
NM_145286STOML31
XM_001133760ZNF5191
NM_000750CHRNB41
NM_022963FGFR41
NM_213647FGFR41
NM_002011FGFR41
NM_0208831
NM_207034EDN31
NM_000114EDN31
NM_207032EDN31
NM_207033EDN31
NM_012244SLC7A81
NM_182728SLC7A81
NM_001261CDK91
NM_001292CLK31
NM_001081472SPATA11
NM_001003407ABLIM11
NM_001003408ABLIM11
NM_002313ABLIM11
NM_006720ABLIM11
NM_152301MRFAP1L11
NM_000161GCH11
NM_181523PIK3R11
NM_181504PIK3R11
NM_181524PIK3R11
NM_018003UACA1
NM_001008224UACA1
XM_931376SETD51
XM_944260SETD51
XM_931478SETD51
XM_944280SETD51
XM_931417SETD51
XM_944276SETD51
XM_939712SETD51
NM_001080517SETD51
NM_000163GHR1
NM_012288TRAM21
NM_016217HECA1
NM_052906LRRC621
NM_014732KIAA05131
NM_032683FKSG241
NM_001002265MARCH81
NM_145021MARCH81
NM_001002266MARCH81
NM_152462AMAC11
NM_145865ANKS4B1
NM_006850IL241
NM_181339IL241
NM_016403HSPC1481
NM_001018111PODXL1
NM_005397PODXL1
NM_003215TEC1
NM_021117CRY21
NM_133374ZNF6181
NM_007054KIF3A1
NM_016018PHF20L11
NM_153756FNDC51
NM_032439PHYHIPL1
NM_020161DKFZp547H0251
NM_000840GRM31
NM_018401STK32B1
NM_178815ARL5B1
NM_006047RBM121
NM_152838RBM121
NM_024636STEAP41
NM_020462ERGIC11
NM_017729EPS8L11
NM_133180EPS8L11
NM_001204BMPR21
NM_032199ARID5B1
NM_001546ID41
NM_014873LPGAT11
NM_022763FNDC3B1
NM_021813BACH21
NM_205855UNQ19401
NM_005159ACTC11
NM_002709PPP1CB1
NM_206876PPP1CB1
XM_001130343LOC7294671
XM_001133035LOC7323731
NM_001356DDX3X1
NM_021116ADCY11
NM_004455EXTL11
NM_006071PKDREJ1
NM_024963FBXL181
NM_021072HCN11
NM_032300TCHP1
XM_936538FAT31
NM_0010087811
XM_926199FAT31
NM_020449THOC21
NM_001081550THOC21
NM_173793LOC1289771
NM_016507CRKRS1
NM_0150831
NM_003296CRISP21
NM_000089COL1A21
NM_015076CDC2L61
NM_005156ROD11
NM_182562FLJ397431
NM_175733SYT91
NM_031243HNRPA2B11
NM_002137HNRPA2B11
NM_020782KLHDC51
NM_001010000ARHGAP281
NM_004096EIF4EBP21
NM_020886USP281
NM_0333901
NM_031366COL4A31
NM_000091COL4A31
NM_031365COL4A31
NM_031362COL4A31
NM_033199UCN21
NM_033121ANKRD13A1
NM_201253CRB11
XM_001134277LOC2213621
NM_003288TPD52L21
NM_199359TPD52L21
NM_199362TPD52L21
NM_199360TPD52L21
NM_199363TPD52L21
NM_199361TPD52L21
NM_001011718XKR71
NM_152547BTNL91
NM_016495TBC1D71
NM_001458FLNC1
NM_024896KIAA18151
NM_014421DKK21
NM_0011031671
NM_012138AATF1
NM_176806MOCS21
NM_004531MOCS21
NM_006345SLC30A91
NM_024060AHNAK1
NM_199129Kua1
NM_019593KIAA14341
NM_020872CNTN31
NM_207647FSD1L1
NM_003392WNT5A1
NM_0056401
NM_020207C9orf1021
NM_017770ELOVL21
NM_015192PLCB11
NM_182734PLCB11
NM_004923MTL51
NM_015336ZDHHC171
NM_004975KCNB11
NM_002851PTPRZ11
NM_207429FLJ458031
NM_138287DTX3L1
NM_018683ZNF3131
NM_003838FPGT1
NM_0011127361
NM_015224C3orf631
NM_181308WDR201
NM_144574WDR201
NM_181302WDR201
NM_145290GPR1251
XM_001131071GPR1251
NM_015230CENTD11
NM_139182CENTD11
NM_000890KCNJ51
NM_181889UBE2D31
NM_181888UBE2D31
NM_181887UBE2D31
NM_181893UBE2D31
NM_181892UBE2D31
NM_003340UBE2D31
NM_181886UBE2D31
NM_181890UBE2D31
NM_181891UBE2D31
NM_003847PEX11A1
NM_004132HABP21
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_018222PARVA1
NM_015235CSTF2T1
NM_004162RAB5A1
NM_016025METTL91
NM_001077180METTL91
NM_001800CDKN2D1
NM_079421CDKN2D1
NM_153346CXorf201
NM_001039569AP1S31
NM_024871MAP6D11
NM_003483HMGA21
NM_183238ZNF6051
NM_032361THOC31
NM_002351SH2D1A1
NM_032680EFCAB4B1
NM_032303HSDL21
NM_001982ERBB31
NM_003861WDR221
NM_018590GALNACT-21
NM_002078GOLGA41
NM_024866ADM21
NM_207645LOC3999471
NM_004282BAG21
NM_032019HDAC101
NM_014933SEC31A1
NM_016211SEC31A1
NM_001077207SEC31A1
NM_001077208SEC31A1
NM_001077206SEC31A1
NM_004621TRPC61
NM_016530RAB8B1
XM_001131899LOC2839041
NM_0010992721
NM_152733BTBD91
NM_0528931
NM_001017408GOPC1
NM_020399GOPC1
NM_006485FBLN11
NM_015035ZHX31
NM_152734C6orf891
NM_194071CREB3L21
NM_015935KIAA08591
NM_014955KIAA08591
NM_001007239KIAA08591
NM_006903PPA21
NM_176866PPA21
NM_176869PPA21
NM_176867PPA21
NM_001034191PPA21
XM_001128917LOC7312401
XM_001126538LOC7281031
NM_183236RAB27A1
NM_004580RAB27A1
NM_183234RAB27A1
NM_183235RAB27A1
NM_002563P2RY11
NM_175876EXOC81
NM_002628PFN21
NM_053024PFN21
NM_001002860BTBD71
NM_001011513PDLIM51
NM_006457PDLIM51
NM_207322NLF11
NM_022897RANBP171
NM_001364DLG21
NM_004852ONECUT21
NM_173649FLJ401721
NM_000834GRIN2B1
NM_017686GDAP21
NM_019026TMCO11
NM_013302EEF2K1
NM_152991EED1
NM_003797EED1
NM_001077196PDE11A1
NM_001077197PDE11A1
NM_016953PDE11A1
NM_001039577CCNL21
NM_001009552PPP2CB1
NM_004156PPP2CB1
NM_018099MLSTD11
NM_004426PHC11
XM_934166LOC6534411
XM_945184LOC6534411
NM_004286GTPBP11
NM_005990STK101
NM_006393NEBL1
NM_014982PCNX1
NM_015631C10orf611
NM_014743KIAA02321
NM_0011005901
NM_153274BEST41
NM_001044370MPPED11
NM_032505KBTBD81
NM_021964ZNF1481
NM_000318PXMP31
NM_001079867PXMP31
NM_020698TMCC31
NM_080743SRrp351
NM_021183RAP2C1
NM_138450ARL111
NM_032817ITIH51
NM_030569ITIH51
NM_001781CD691
NM_0011055531
NM_0011055541
NM_018300ZNF831
NM_0011055501
NM_0011055511
NM_0011055521
NM_0011055491
NM_017848FAM120C1
NM_000436OXCT11
NM_025189ZNF4301
NM_152446C14orf1451
XM_001132013ANKH1
XM_930496LOC6457521
XM_370876LOC6536431
NM_018652GOLGA1
XM_496076LOC6536411
NM_001038640GOLGA61
NM_198181LOC4402951
XM_001130526LOC7286361
XM_001130555LOC7286361
XM_001130543LOC7286361
XM_001130536LOC7286361
XM_001129399LOC6423461
XM_928707LOC6423461
XM_925879LOC6423461
XM_933066LOC6436961
XM_925864LOC6423251
XM_929030LOC1615271
NM_005509DMXL11
NM_004869VPS4B1
NM_003338UBE2D11
NM_001024855ZNF1971
NM_005722ACTR21
NM_001005386ACTR21
NM_020385REXO41
NM_001029864KIAA17551
NM_0010988191
NM_0010988181
NM_000923PDE4C1
NM_145173DIRAS11
NM_173806C16orf651
NM_0208551
NM_023923PHACTR41
NM_001048183PHACTR41
NM_133181EPS8L31
NM_024526EPS8L31
NM_139053EPS8L31
NM_152660FAM76A1
NM_001531MR11
NM_024577SH3TC21
NM_1449931
NM_183380DST1
NM_015548DST1
NM_152745NXPH11
XM_001128799MAP3K21
NM_017738C9orf391
XM_936273ZSWIM61
XM_035299ZSWIM61
NM_014795ZEB21
NM_152835PDIK1L1
NM_152614MGC351541
NM_003269NR2E11
NM_001081686G6PC21
NM_203282ZNF2541
NM_005669REEP51
NM_054030MRGPRX21
NM_001001331ATP2B21
NM_001683ATP2B21
NM_006496GNAI31
XM_376795FLJ458721
XM_940037FLJ458721
NM_005238ETS11
NM_014797ZBTB241
NM_006109PRMT51
NM_001039619PRMT51
NM_033267IRX21
NM_134424RAD521
NM_000908NPR31
NM_198581ZC3H61
NM_176894P2RY131
NM_023914P2RY131
NM_001303COX101
NM_006622PLK21
NM_007275TUSC21
NM_014586HUNK1
NM_052917GALNT131
XM_001127175LOC7283201
NM_015263DMXL21
NM_001626AKT21
NM_203406LOC1533641
NM_025152NUBPL1
NM_024012HTR5A1
NM_152793C7orf411
NM_000208INSR1
NM_001079817INSR1
NM_001017995SH3PXD2B1
NM_181351NCAM11
NM_000615NCAM11
NM_203305FAM102A1
NM_001035254FAM102A1
NM_015635GAPVD11
NM_003339UBE2D21
NM_181838UBE2D21
NM_003161RPS6KB11
NM_005986SOX11
NM_018718TSGA141
NM_018697LANCL21
XM_001133927LOC7295071
XM_001133906LOC7317301
NM_002847PTPRN21
NM_130843PTPRN21
NM_130842PTPRN21
NM_0154731
NM_0152951
NM_004553NDUFS61
NM_152636METT5D11
NM_153764KCNJ11
NM_153766KCNJ11
NM_000220KCNJ11
NM_153765KCNJ11
NM_153767KCNJ11
NM_014840NUAK11
NM_001310CREBL21
NM_003620PPM1D1
NM_016275SELT1
NM_032346PDCD2L1
XM_001133026LOC7313861
XM_001133204LOC7291201
NM_020946DENND1A1
NM_006033LIPG1
NM_003128SPTBN11
NM_0011004271
NM_021159RAP1GDS11
NM_0011004281
NM_0011004291
NM_0011004261
NM_0011004301
NM_0011055731
NM_003478CUL51
NM_020826SYT131
NM_001160APAF11
NM_181868APAF11
NM_181869APAF11
NM_013229APAF11
NM_181861APAF11
NM_203390RBM12B1
NM_1779662'-PDE1
NM_031890CECR61
NM_152686DNAJC181
NM_182898CREB51
NM_004904CREB51
NM_001011666CREB51
NM_182899CREB51
NM_015892GALNAC4S-6ST1
NM_152320ZNF6411
NM_000103CYP19A11
NM_031226CYP19A11
NM_000272NPHP11
NM_019604CRTAM1
NM_181787DPY19L41
NM_052916RNF1571
NM_002664PLEK1
NM_000813GABRB21
NM_021911GABRB21
NM_012325MAPRE11
NM_175852TXLNA1
NM_177402SYT21
NM_013252CLEC5A1
NM_198401ANKRD461
NM_024090ELOVL61
NM_020147THAP101
NM_013345GPR1321
NM_024959SLC24A61
NM_017741C4orf301
NM_177951PPM1A1
NM_005392PHF21
NM_182916TRNT11
XM_001128336LOC7281521
XM_001133734LOC7317421
NM_032569N-PAC1
NM_005814GPA331
NM_138467TYW31
NM_014034ASF1A1
NM_021783EDA2R1
NM_001033047NPNT1
NM_005909MAP1B1
NM_014145C20orf301
NM_001009923C20orf301
NM_001009924C20orf301
NM_001009925C20orf301
NM_021137TNFAIP11
NM_001077199SFRS121
NM_139168SFRS121
NM_172318KCNG11
NM_025179PLXNA21
NM_003012SFRP11
NM_015216HISPPD11
NM_004768SFRS111
NM_024594PANK31
NM_021572ENPP51
NM_175064WBSCR191
XM_499348MGC573591
XM_001127525LOC7303071
XM_496899LOC4412581
XM_929470LOC6439091
XM_001127430LOC7303041
NM_001003712OSBPL81
NM_020841OSBPL81
NM_022832USP461
NM_018153ANTXR11
NM_030648SETD71
NM_031935HMCN11
NM_014612FAM120A1
NM_003452ZNF1891
NM_197977ZNF1891
NM_006549CAMKK21
NM_153499CAMKK21
NM_153500CAMKK21
NM_172216CAMKK21
NM_172226CAMKK21
NM_182686KIAA0319L1
NM_020832ZNF6871
NM_012290TLK11
NM_015071ARHGAP261
NM_000170GLDC1
NM_001042467MLPH1
NM_024101MLPH1
NM_032436C13orf81
NM_198150ARSK1
NM_015046SETX1
NM_025146NAT131
NM_024607PPP1R3B1
NM_015288PHF151
NM_016059PPIL11
NM_002841PTPRG1
NM_021949ATP2B31
NM_001001344ATP2B31
NM_207406CCDC41
NM_015025MYT1L1
NM_012192FXC11
NM_020804PACSIN11
NM_025222TMEM1131
NM_015621CCDC691
NM_014351SULT4A11
NM_001012755MCART61
NM_003034ST8SIA11
XM_001130364LOC7284171
XM_001130184LOC7308431
XM_379273FLJ141861
NM_012388PLDN1
NM_004277SLC25A271
NM_002833PTPN91
XM_001128975PTPN91
NM_173632ZNF7761
NM_153035C1orf831
NM_006803AP3M21
NM_001939DRP21
NM_052966FAM129A1
NM_018122DARS21
NM_020335VANGL21
XM_939750USP321
NM_032582USP321
NM_004505USP61
NM_006282STK41
NM_000914OPRM11
NM_014961RUFY31
NM_001328CTBP11
NM_001012614CTBP11
NM_000623BDKRB21
NM_201628FLJ438061
NM_013290PSMC3IP1
NM_016556PSMC3IP1
NM_024628SLC12A81
NM_152380TBX151
NM_021133RNASEL1
NM_004247EFTUD21
NM_178832C10orf831
NM_0010988311
NM_001018116LOC3472731
NM_004948DSC11
NM_024421DSC11
NM_006361HOXB131
NM_020689SLC24A31
XM_001130036LOC7308151
XM_001132008LOC7287691
NM_017594DIRAS21
NM_182970RIMS41
NM_002427MMP131
NM_0212411
NM_207168ENSA1
NM_005270GLI21
NM_0011013871
NM_033223GABRG31
NM_016282AK31
NM_003112SP41
NM_001017964LOC1502231
NM_001033554SPECC11
NM_152904SPECC11
NM_153487MDGA11
NM_024713C15orf291
NM_020982CLDN91
NM_153347TMEM86A1
NM_001009555SH3D191
NM_001004303C1orf1681
NM_181553CMTM31
NM_001048251CMTM31
NM_181554CMTM31
NM_144601CMTM31
NM_006734HIVEP21
NM_001040152PEG101
NM_015068PEG101
NM_032123KIRREL21
NM_199180KIRREL21
NM_199179KIRREL21
NM_0011006211
NM_017941C17orf801
XM_928167LOC6451371
XM_001126877LOC7280471
XM_001126928LOC7280471
XM_001126912LOC7280471
XM_926998LOC6436991
XM_001126904LOC7280471
XM_001127034LOC7280801
XM_001127051LOC7280801
XM_001127002LOC7280801
XM_001127022LOC7280801
XM_001126392LOC7279091
XM_001126407LOC7279091
XM_001126378LOC7279091
NM_001023567GOLGA8B1
NM_181077GOLGA8A1
NM_001012423GOLGA8E1
NM_001012452FLJ326791
NM_001012420GOLGA8G1
NM_0011127341
NM_000282PCCA1
NM_001014283DCUN1D21
NM_006479RAD51AP11
NM_001649SHROOM21
NM_138700TRIM401
NM_020133AGPAT41
NM_173654C3orf641
NM_152309PIK3AP11
NM_006706TCERG11
NM_001040006TCERG11
NM_032487ARPM11
NM_139245PPM1L1
NM_000448RAG11
XM_001134327LOC7323241
XM_001134208LOC7299751
NM_014303PES11
NM_001026213CYP11B11
NM_000497CYP11B11
NM_018170P15RS1
NM_001012958DISC11
NM_017488ADD21
NM_017483ADD21
NM_001617ADD21
NM_153026PRICKLE11
NM_017425SPA171
NM_022444SLC13A11
NM_138473SP11
NM_015948SLC35B31
XM_001129173LOC7313141
NM_001037582SCD51
NM_138704NDNL21
NM_024312GNPTAB1
NM_032933C18orf451
NM_018230NUP1331
NM_015141GPD1L1
NM_003298NR2C21
NM_000259MYO5A1
NM_014607UBXD21
NM_001029955WDR21B1
NM_001867COX7C1
NM_0207801
NM_053064GNG21
NM_016297PCYOX11
NM_016563RASL121
NM_182966NEDD91
NM_001025356TMEM16F1
NM_022776OSBPL111
XM_931945LOC6439621
XM_943665LOC6439621
NM_019591ZNF261
NM_001005733C21orf341
NM_001005734C21orf341
NM_001005732C21orf341
NM_000909NPY1R1
NM_001079878CNGA31
NM_001298CNGA31
NM_182700SP81
NM_198956SP81
NM_024884L2HGDH1
NM_006544EXOC51
NM_018640LMO31
NM_001001395LMO31
NM_004504HRB1
NM_000340SLC2A21
XM_001126688LOC7306521
XM_001127390LOC7283971
NM_004846EIF4E21
NM_022841RFXDC21
NM_005742PDIA61
NM_005497GJA71
NM_001080383GJA71
NM_001005473PLCXD31
NM_006322TUBGCP31
NM_006176NRGN1
NM_181597UPP11
NM_003364UPP11
NM_014798PLEKHM11
XM_001128220PLEKHM11
NM_001010874SRD5A2L21
NM_024745SHCBP11
NM_014323PATZ11
NM_032052PATZ11
NM_032050PATZ11
NM_002154HSPA41
NM_006893LGTN1
NM_004488GP51
NM_003799RNMT1
NM_020954KIAA16181
NM_001010922C1orf1781
NM_021705NFYA1
NM_002505NFYA1
NM_020242KIF151
NM_018157RIC8B1
NM_198549FAM73A1
NM_198076FAM36A1
NM_006727CDH101
NM_030971SFXN31
NM_005134PPP4R11
NM_001042388PPP4R11
NM_003400XPO11
XM_938268TBX181
NM_001080508TBX181
NM_016542MST41
NM_001042452MST41
NM_001042453MST41
NM_006031PCNT1
NM_004941DHX81
NM_017705PAQR51
NM_0011045541
XM_001125898LOC7277621
NM_198128RNF1381
NM_016271RNF1381
NM_016028SUV420H11
NM_032781PTPN51
NM_001039970PTPN51
NM_006906PTPN51
NM_053056CCND11
NM_001503GPLD11
XM_001130382LOC7308551
XM_001134429MUC5AC1
NM_181507HPS51
NM_007216HPS51
NM_181508HPS51
NM_173808NEGR11
NM_198491FAM92B1
NM_002613PDPK11
NM_031268PDPK11
NM_173829P18SRP1
NM_012193FZD41
XM_001132901LOC7302001
XM_001133006LOC7323681
NM_153717EVC1
NM_144977DENND1B1
NM_152578FMR1NB1
NM_003477PDHX1
NM_080415SEPT41
NM_012233RAB3GAP11
NM_052931SLAMF61
NM_152424FAM123B1
NM_001017396ZNF21
NM_021088ZNF21
NM_002451MTAP1
NM_005036PPARA1
NM_001001928PPARA1
NM_014521SH3BP41
NM_002806PSMC61
NM_003411ZFY1
NM_003410ZFX1
NM_032682FOXP11
NM_152431PIWIL41
NM_001005339RGS101
NM_002925RGS101
NM_022899ACTR81
NM_207002BCL2L111
NM_021825CCDC90B1
NM_012158FBXL31
NM_182831TNT1
NM_003885CDK5R11
NM_012162FBXL61
NM_024555FBXL61
NM_173694ATP11C1
NM_001010986ATP11C1
NM_020456C13orf11
NM_015026MON21
NM_147129ALS2CL1
NM_182775ALS2CL1
NM_022160DMRTA11
NM_016169SUFU1
NM_207015NAALADL21
NM_000824GLRB1
NM_152869RGN1
NM_004683RGN1
NM_001677ATP1B11
NM_004094EIF2S11
NM_001012393OPCML1
NM_002545OPCML1
NM_182485CPEB21
NM_182646CPEB21
NM_001040285PAPD51
NM_001040284PAPD51
NM_014820TOMM70A1
NM_012431SEMA3E1
NM_032977CASP101
NM_001230CASP101
NM_018373SYNJ2BP1
NM_015449C1orf431
NM_0010986161
NM_138740C1orf431
NM_001271CHD21
NM_014071NCOA61
XM_001125792LOC7278341
XM_926013LOC6423981
NM_133264WIPF21
NM_153711FAM26E1
NM_006489NOVA11
NM_002515NOVA11
XM_937761LOC2840671
XM_208990LOC2840671
NM_005502ABCA11
NM_017931FLJ206991
NM_017762MTMR101
NM_033117RBM181
NM_002740PRKCI1
NM_001039770FLJ450321
NM_014710GPRASP11
NM_0010994101
NM_0010994111
NM_032778MINA1
NM_153182MINA1
NM_001042533MINA1
NM_001009571CADPS21
NM_017954CADPS21
NM_138803LOC1309401
NM_206943LTBP11
NM_000627LTBP11
NM_021979HSPA21
XM_001130627LOC7295591
NM_018200HMG20A1
NM_033313CDC14A1
NM_198715PTGER31
NM_005407SALL21
NM_000663ABAT1
NM_020686ABAT1
NM_006310NPEPPS1
NM_018243SEPT111
NM_002069GNAI11
NM_012164FBXW21
NM_003677DENR1
NM_022893BCL11A1
XM_939663KIAA15531
NM_001080450KIAA15531
NM_030660ATXN31
NM_004993ATXN31
NM_014504RABGEF11
XM_001126195LOC7279421
NM_015564LRRTM21
NM_006070TFG1
NM_001007565TFG1
NM_006315PCGF31
NM_004866SCAMP11
NM_003971SPAG91
NM_001004334GPR1791
NM_145813AIFM11
NM_145812AIFM11
NM_004208AIFM11
NM_213651SLC25A241
NM_013386SLC25A241
NM_006548IGF2BP21
NM_001007225IGF2BP21
NM_005333HCCS1
NM_024915GRHL21
NM_019069WDR5B1
NM_004764PIWIL11
NM_014636RALGPS11
NM_015277NEDD4L1
NM_198506FLJ446911

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
Motif found in sense strand

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317