Predicted Off-targets for siRNA "ggauguaauggaagugcua" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

26 hits were found for GGAUGUAAUGGAAGUGCUA (19 guide strand hits and 7 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_183376 ARRDC4 1650 1668 GaAUGUAAUGGAAGUcCUg57 3 13 c false   <90%   4071
NM_023037 FRY 6214 6232 uuAUGUAAUGGAAGcGCUc56 4 12 c false   <90%   10718
NM_080921 PTPRC 1093 1111 caAcGUAAUGGAAGUGCUg44 4 14 bc false   <90%   4847
NM_080922 PTPRC 1432 1450 caAcGUAAUGGAAGUGCUg44 4 14 bc false   <90%   5186
NM_002838 PTPRC 1576 1594 caAcGUAAUGGAAGUGCUg44 4 14 bc false   <90%   5330
NM_001042355 CYLD 1598 1616 GucUGUAAUGGAAGaGCUA44 3 11 c false   <90%   8584
NM_001042412 CYLD 1622 1640 GucUGUAAUGGAAGaGCUA44 3 11 c false   <90%   8608
NM_015247 CYLD 1744 1762 GucUGUAAUGGAAGaGCUA44 3 11 c false   <90%   8730
XR_018354 LOC646792 715 733 GugaGUAAUGGAAGUGCUu27 4 14 bc false   <90%   879
XR_017300 LOC646792 715 733 GugaGUAAUGGAAGUGCUu27 4 14 bc false   <90%   879
NM_021729 VPS11 1026 1044 GGAUGUAgUGGAuGUGCUu22 3 7   false   <90%   3279
NM_006048 UBE4B 1298 1316 GauUuUAAUGGAAGUGCUA17 3 14 bc false   <90%   5512
NM_014733 ZFYVE16 3924 3942 uGAUGUAAUGaAAGUaCUA10 3 9 c false   <90%   6280
NM_019012 PLEKHA5 2304 2322 GGAUGUcAUGGAAGgGCUg4 3 7 c false   <90%   4253
NM_006955 ZNF33B 5227 5245 cauUGUAcUGGAAGUGCUA4 4 11 bc false   <90%   5958
NM_006974 ZNF33A 5385 5403 cauUGUAcUGGAAGUGCUA4 4 11 bc false   <90%   6127
NM_006954 ZNF33A 5388 5406 cauUGUAcUGGAAGUGCUA4 4 11 bc false   <90%   6130
NM_015350 LRRC8B 1881 1899 aacUGaAAUGGAAGUGCUA3 4 13 bc false   <90%   3588
NM_014682 ST18 2866 2884 GGAUGUgAUGGAAGUGgcc2 4 9 c false   <90%   6183


Hits to Sense strand








AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_019109 ALG1 1039 1057 aAGCACUUCCAgcACAUCC53 3 10   false   <90%   2149
NM_022162 NOD2 2256 2274 aAGCACUUCCAcUcCAUCC44 3 10   false   <90%   4485
NM_183374 CYP26C1 1337 1355 agcCgCUUCCAUUACAUCC15 4 14 bc false   <90%   1569
NM_032129 PLEKHN1 194 212 aAGCuCUUCCAcUACAUCC12 3 7   false   <90%   2418
NM_015540 RPAP1 4472 4490 gAGCcCUaCCAUUACAUCC-15 3 11 bc false   <90%   4698
NM_003041 SLC5A2 1372 1390 cAGCuCUUCgAUUACAUCC-36 3 9 bc false   <90%   2271
NM_022167 XYLT2 886 904 cAGCACUUCuuUUACAUCC-46 3 8 c false   <90%   3567


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1351
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_198150ARSK3
NM_017650PPP1R9A3
NM_152622MIER33
NM_006420ARFGEF22
NM_000217KCNA12
NM_006850IL242
NM_181339IL242
NM_006135CAPZA12
XM_941644LOC3998812
NM_018362LIN7C2
XM_939083TTC282
XM_929318TTC282
NM_001969EIF52
NM_183004EIF52
NM_001083603PTCH12
NM_001083607PTCH12
NM_001083602PTCH12
NM_001083605PTCH12
NM_001083606PTCH12
NM_001083604PTCH12
NM_000264PTCH12
NM_198461LONRF22
NM_006714SMPDL3A2
NM_004136IREB22
NM_017658KLHL282
NM_031866FZD82
NM_017637BNC22
NM_130811SNAP252
NM_003081SNAP252
NM_025010KLHL182
NM_005520HNRPH12
NM_033429CALML42
NM_001031733CALML42
NM_007050PTPRT2
NM_133170PTPRT2
NM_018999KIAA11282
NM_007049BTN2A12
NM_078476BTN2A12
NM_021181SLAMF72
NM_005935AFF12
NM_006282STK42
NM_001083112GPD22
NM_000408GPD22
NM_181435C1QTNF32
NM_030945C1QTNF32
NM_005898CAPRIN12
NM_012193FZD42
NM_058170OLFM32
NM_007249KLF122
NM_152418WDR21C2
NM_005160ADRBK22
NM_022162NOD22
NM_001077394DPH52
NM_001077395DPH52
NM_015958DPH52
NM_005551KLK22
NM_001002231KLK22
NM_001338CXADR2
XM_935722LOC6467622
XM_938418LOC6467622
NM_033274ADAM192
NM_001001995GPM6B2
NM_014553TFCP2L12
XM_001132013ANKH2
NM_017944USP472
NM_017628KIAA15462
NM_173544FAM129C2
NM_002336LRP62
NM_006052DSCR32
NM_001040653ZXDC2
NM_001001420SMAD52
NM_001001419SMAD52
NM_005903SMAD52
NM_014874MFN22
NM_1735692
NM_006854KDELR22
NM_0011006032
NM_015338ASXL12
NM_032873STS-12
NM_021129PPA12
NM_016021UBE2J12
NM_024511C4orf152
NM_153332THEX12
NM_017759FLJ203092
NM_004536NAIP1
NM_022892NAIP1
XM_001127632LOC7285191
NM_004237TRIP131
NM_001040171HTR41
NM_002146HOXB31
NM_153453VGLL21
NM_182645VGLL21
NM_0010996931
NM_002604PDE7A1
NM_006903PPA21
NM_176866PPA21
NM_176869PPA21
NM_176867PPA21
NM_001034191PPA21
XM_378742FLJ459941
XM_943185FLJ459941
NM_014488RAB301
NM_145280FAM119A1
NM_015200SCC-1121
NM_0011003991
NM_002062GLP1R1
NM_004822NTN11
NM_033285TP53INP11
NM_018367PHCA1
NM_020639RIPK41
NM_000337SGCD1
NM_006775QKI1
NM_015938NMD31
NM_003034ST8SIA11
NM_207467FLJ355301
XM_001131702LOC1527421
XM_001128848LOC1527421
NM_006750SNTB21
NM_0010808261
NM_173536GABRG11
NM_001039762FLJ455571
NM_016484PDZD111
NM_201252AFAR31
NM_001009922RCHY11
NM_001008925RCHY11
NM_015436RCHY11
NM_022912REEP11
NM_018640LMO31
NM_001001395LMO31
NM_176081TRDMT11
NM_004412TRDMT11
NM_176083TRDMT11
NM_017748CCDC491
NM_0010853991
NM_001001936AFAP1L21
NM_032550AFAP1L21
NM_001008493ENAH1
NM_018212ENAH1
NM_002203ITGA21
XM_001130507LOC7317081
XM_001127823LOC7285731
NM_001042517DIAPH31
NM_018373SYNJ2BP1
NM_014817KIAA06441
NM_017922PRPF391
NM_000376VDR1
NM_001017535VDR1
NM_000112SLC26A21
NM_004774PPARBP1
NM_001128AP1G11
NM_001030007AP1G11
NM_002858ABCD31
NM_019009TOLLIP1
NM_016643ZNF7711
XM_939663KIAA15531
NM_001080450KIAA15531
NM_001083589E2F51
NM_001083588E2F51
NM_001951E2F51
NM_004850ROCK21
NM_181727SPATA121
NM_012399PITPNB1
XM_936926SERF1A1
XM_001130874LOC7284921
NM_133464ZNF4831
NM_018325C9orf721
NM_139167SGCZ1
NM_006544EXOC51
NM_001080541MGA1
XM_932727MGA1
XM_939296MGA1
XM_944092MGA1
NM_006988ADAMTS11
NM_018082POLR3B1
NM_022497MRPS251
NM_020299AKR1B101
NM_004282BAG21
NM_0010897041
NM_015646RAP1B1
NM_001010942RAP1B1
XM_001127950LOC7305661
XM_001133333LOC7291721
NM_017776ZNF6731
NM_0011024021
NM_021213PCTP1
NM_019857CTPS21
NM_175859CTPS21
NM_000084CLCN51
NM_021240DMRT31
NM_015277NEDD4L1
NM_020826SYT131
NM_002264KPNA11
NM_018058CRTAC11
NM_005347HSPA51
NM_000242MBL21
NM_015847MBD11
NM_015844MBD11
NM_002384MBD11
NM_015846MBD11
XM_001126151LOC7278581
XM_001130844LOC7287641
NM_000919PAM1
NM_138766PAM1
NM_138821PAM1
NM_138822PAM1
NM_001042599ERBB41
NM_005235ERBB41
NM_001080485ZNF2751
NM_212555C11orf381
NM_198174GRHL31
NM_021180GRHL31
NM_198173GRHL31
NM_000061BTK1
NM_024923NUP2101
NM_148170CTSC1
NM_033272KCNH71
NM_0148561
NM_0010987211
NM_0010987221
NM_004485GNG41
NM_016520C9orf781
NM_003820TNFRSF141
NM_004685MTMR61
NM_032509RBM131
NM_001039840CHIC11
NM_0122741
NM_021077NMB1
NM_001560IL13RA11
NM_014021SSX2IP1
NM_144690ZNF5821
NM_024993LRRTM41
NM_014577BRD11
NM_004730ETF11
XM_001127102LOC6478591
XM_001130815LOC6478591
NM_016620ZNF6441
NM_201269ZNF6441
NM_032186ZNF6441
NM_020776KIAA13281
NM_198595AFAP11
NM_021638AFAP11
NM_018388MBNL31
NM_133486MBNL31
XM_934407LOC6471311
XM_945302LOC6522251
NM_002655PLAG11
NM_030817APOLD11
NM_021809TGIF21
XM_934619LOC2845771
XM_945015LOC2845771
NM_138400NOM11
NM_001083592ROR11
NM_001080439HSF51
XM_939614HSF51
NM_019605SERTAD41
NM_020676ABHD61
NM_004393DAG11
NM_005923MAP3K51
NM_017768LRRC401
NM_138991BACE21
NM_138992BACE21
NM_012105BACE21
NM_0010992891
NM_0010985001
NM_019590KIAA12171
NM_0010985011
NM_003559PIP5K2B1
NM_172177MRPL421
NM_172178MRPL421
NM_014050MRPL421
NM_152718VWCE1
NM_001965EGR41
NM_000809GABRA41
NM_006626ZBTB61
NM_000189HK21
XM_001132090LOC7300151
NM_001037954DIXDC11
NM_033425DIXDC11
NM_014751MTSS11
NM_012305AP2A21
NM_031483ITCH1
NM_012269HYAL41
NM_000733CD3E1
NM_006016CD1641
NM_019850NGEF1
NM_021251CAPN101
NM_023083CAPN101
NM_023085CAPN101
NM_199126ZNF585A1
NM_152655ZNF585A1
NM_030934C1orf251
NM_016076C1orf1211
XM_930224LOC6471901
XM_941815LOC6471901
NM_019001XRN11
NM_001042604XRN11
NM_017915C12orf481
NM_031444C22orf131
NM_020119ZC3HAV11
NM_014820TOMM70A1
NM_001040177AKR1CL21
NM_020424LYRM11
NM_014700RAB11FIP31
NM_018191RCBTB11
NM_198836ACACA1
NM_198837ACACA1
NM_198834ACACA1
NM_198838ACACA1
NM_198839ACACA1
NM_020375C12orf51
NM_004854CHST101
NM_182609ZNF6771
NM_001010984C1orf1241
NM_004557NOTCH41
NM_021163RBAK1
NM_004863SPTLC21
NM_198261RSRC21
NM_198262RSRC21
NM_023012RSRC21
NM_014037SLC6A161
XM_930748LOC6423611
XM_498491LOC4399941
NM_019894TMPRSS41
NM_0010839471
NM_032510PARD6G1
NM_203374ZNF7841
NM_016829OGG11
NM_016826OGG11
NM_016827OGG11
NM_016828OGG11
NM_016821OGG11
NM_033339CASP71
NM_001227CASP71
NM_033340CASP71
NM_033338CASP71
NM_024707GEMIN71
NM_001007270GEMIN71
NM_001007269GEMIN71
NM_001030060SAMD51
NM_024769ASAM1
NM_1522931
NM_004227PSCD31
NM_014945ABLIM31
NM_178831GATS1
NM_018717MAML31
NM_001009993LOC1300741
NM_006099PIAS31
NM_173484KLF171
NM_182679GPATCH41
NM_015590GPATCH41
NM_004956ETV11
NM_003339UBE2D21
NM_181838UBE2D21
NM_015570AUTS21
NM_015367BCL2L131
NM_020474GALNT11
NM_014906PPM1E1
NM_014899RHOBTB31
NM_020943KIAA16041
XM_001127597FLJ328101
XM_001127587FLJ328101
XM_925815FLJ328101
XM_001127637FLJ328101
XM_001127623FLJ328101
NM_032664FUT101
NM_001017369SC4MOL1
NM_006745SC4MOL1
XM_001134281LOC7301391
XM_001134203LOC7322631
NM_182848CLDN101
NM_006984CLDN101
NM_138768MYEOV1
NM_199421SOCS41
NM_080867SOCS41
NM_153685C12orf531
NM_015084MRPS271
NM_001005609EDA1
NM_001399EDA1
NM_014897ZNF6521
NM_022757CCDC141
NM_144770RBM111
NM_001523HAS11
NM_005788PRMT31
NM_182562FLJ397431
NM_0010983981
NM_004371COPA1
NM_003262TLOC11
NM_001013659ZNF7931
XM_001131640LOC7320281
XM_941403LOC6447901
XM_927887LOC6447901
XM_937120LOC6480681
XM_373027LOC3916561
NM_001030009RPS15A1
NM_001019RPS15A1
NM_020128MDM11
NM_016195MPHOSPH11
NM_001014797KCNMA11
NM_022753S100PBP1
NM_194293CMYA11
NM_006661PDE10A1
NM_018196TMLHE1
NM_002497NEK21
NM_182485CPEB21
NM_182646CPEB21
NM_014408TRAPPC31
NM_005832KCNMB21
NM_181361KCNMB21
NM_004921CLCA31
NM_152395NUDT161
NM_017745BCOR1
NM_024611NARG21
NM_001018089NARG21
NM_021813BACH21
NM_014953DIS31
NM_032811TBRG11
NM_173667FLJ375431
NM_000602SERPINE11
NM_153188TNPO11
NM_002270TNPO11
NM_001025252TPD521
NM_001025253TPD521
NM_005079TPD521
NM_001017978LOC2034131
NM_001010883FAM102B1
NM_001029858SLC35F11
NM_000245MET1
NM_024835ZNF4031
NM_184234RBM391
NM_004902RBM391
NM_001037164ARL4A1
NM_005738ARL4A1
NM_212460ARL4A1
XM_929878LOC6469151
NM_020482FHL51
NM_004186SEMA3F1
NM_0010129671
NM_138775ALKBH81
NM_153689FLJ389731
NM_172239REXO1L11
NM_144498OSBPL21
NM_014835OSBPL21
NM_014411NAG81
NM_031418TMEM16C1
NM_0011098781
NM_016954TBX221
NM_0011098791
NM_001002258ATP5G31
NM_001689ATP5G31
NM_000885ITGA41
NM_018489ASH1L1
NM_177968PPM1B1
NM_182608ANKRD331
NM_004509SP1101
NM_080424SP1101
NM_032124HDHD21
NM_032291SGIP11
NM_005400PRKCE1
NM_015313ARHGEF121
NM_006226PLCL11
NM_022736MFSD11
NM_022154SLC39A81
NM_021079NMT11
NM_005604POU3F21
NM_021800DNAJC121
NM_018584CAMK2N11
NM_007370RFC51
NM_181578RFC51
NM_003471KCNAB11
NM_172159KCNAB11
NM_172160KCNAB11
NM_145804ABTB21
NM_001649SHROOM21
NM_001024647RAB3IP1
NM_022456RAB3IP1
NM_175624RAB3IP1
NM_175625RAB3IP1
NM_175623RAB3IP1
NM_139179DAGLB1
NM_003253TIAM11
NM_201266NRP21
NM_003872NRP21
NM_201279NRP21
NM_152636METT5D11
NM_032117MND11
NM_004513IL161
NM_172217IL161
NM_144994ANKRD231
NM_020374C12orf41
NM_0245621
NM_016185HN11
NM_001002032HN11
NM_001002033HN11
NM_181836TMED71
NM_006047RBM121
NM_152838RBM121
NM_206595ESRRG1
NM_001438ESRRG1
NM_206594ESRRG1
NM_014850SRGAP31
NM_001033117SRGAP31
NM_001080494C1orf341
XM_934658C1orf341
XM_945965C1orf341
XM_942427C1orf341
XM_930328C1orf341
XM_945959C1orf341
NM_025188TRIM451
NM_001014342FLG21
NM_194314ZBTB411
NM_014517UBP11
XM_001132925DUSP221
NM_015471NSL11
NM_001042549NSL11
NM_001079514UBN11
NM_016936UBN11
NM_003099SNX11
NM_152826SNX11
NM_148955SNX11
NM_153051MTMR31
NM_021090MTMR31
NM_153050MTMR31
NM_001042669ARHGAP241
NM_001025616ARHGAP241
NM_031305ARHGAP241
NM_002698POU2F21
NM_001006620MAPKAP11
NM_001006619MAPKAP11
NM_001006621MAPKAP11
NM_024117MAPKAP11
NM_001006617MAPKAP11
NM_152546SRFBP11
NM_020123TM9SF31
NM_007057ZWINT1
NM_032997ZWINT1
NM_001005413ZWINT1
NM_022898BCL11B1
NM_138576BCL11B1
NM_145256LRRC251
NM_015456COBRA11
XM_001133009COBRA11
NM_002160TNC1
NM_020808SIPA1L21
NM_153035C1orf831
NM_173808NEGR11
NM_005147DNAJA31
NM_001003940BMF1
NM_001003943BMF1
NM_001003942BMF1
NM_033503BMF1
NM_015001SPEN1
NM_153260LRRC571
NM_012259HEY21
NM_199129Kua1
XM_929714LOC6467621
NM_004925AQP31
NM_006635ZNF4601
NM_144716CCDC121
NM_213598ZNF5431
NM_000399EGR21
NM_175063LOC2843611
NM_002067GNA111
NM_020774MIB11
NM_002607PDGFA1
NM_033023PDGFA1
NM_014167CCDC591
NM_024565CCNJL1
NM_033058TRIM551
NM_184085TRIM551
NM_184086TRIM551
NM_184087TRIM551
NM_033055HIAT11
NM_001017388TLR101
NM_030956TLR101
NM_024675PALB21
NM_007315STAT11
NM_032822FLJ146681
NM_0151231
NM_004133HNF4G1
NM_006827TMED101
NM_0204591
NM_004004GJB21
NM_014797ZBTB241
NM_006060IKZF11
NM_013372GREM11
NM_001148ANK21
NM_020977ANK21
NM_000212ITGB31
NM_006004UQCRH1
NM_0010895911
XM_001129527KLF111
NM_003597KLF111
NM_145166ZBTB471
NM_016823CRK1
NM_005206CRK1
NM_194457UBE2J21
NM_194315UBE2J21
NM_058167UBE2J21
NM_194458UBE2J21
NM_003264TLR21
NM_014106ZNF7701
NM_018208ETNK21
NM_021964ZNF1481
NM_006654FRS21
NM_001042555FRS21
NM_020433JPH21
XM_001130518LOC7284851
XM_001133894LOC7319641
NM_006393NEBL1
NM_017705PAQR51
NM_0011045541
NM_016252BIRC61
NM_145115ZNF4981
NM_000609CXCL121
NM_002636PHF11
NM_024165PHF11
NM_001077440BCLAF11
NM_001077441BCLAF11
NM_014739BCLAF11
NM_145263SPATA181
NM_024092TMEM1091
NM_001025300RAB121
NM_032620GTPBP31
NM_001012965KLK61
NM_002774KLK61
NM_001012964KLK61
NM_198396CACNA1G1
NM_002582PARN1
NM_0011127361
NM_015224C3orf631
NM_000956PTGER21
NM_080629COL11A11
NM_001854COL11A11
NM_080630COL11A11
NM_001003652SMAD21
NM_005901SMAD21
XM_496034LOC6537171
NM_016138COQ71
NM_001007088ZNF1821
NM_006962ZNF1821
NM_017610RNF1111
NM_017583TRIM441
NM_017856GEMIN81
NM_001042479GEMIN81
NM_001042480GEMIN81
NM_020122KCMF11
NM_152628MGC397151
NM_020200PRTFDC11
NM_005789PSME31
NM_176863PSME31
NM_207356C1orf1741
NM_018479ECHDC11
NM_0010020301
NM_0011055441
NM_0011055451
NM_052966FAM129A1
NM_005161AGTRL11
NM_030786SYNC11
NM_006380APPBP21
NM_015194MYO1D1
NM_031845MAP21
NM_031847MAP21
NM_001039538MAP21
NM_002374MAP21
NM_032193RNASEH2C1
NM_001033677CABP11
NM_031205CABP11
NM_004276CABP11
NM_005704PTPRU1
NM_133177PTPRU1
NM_133178PTPRU1
XM_938194LOC1276021
XM_059166LOC1276021
NM_152900MAGI31
NM_001008697TFIP111
NM_012143TFIP111
NM_006489NOVA11
NM_002515NOVA11
NM_021238FAM60A1
NM_012249RHOQ1
NM_018993RIN21
NM_003783B3GALT21
NM_004397DDX61
NM_015215CAMTA11
NM_004094EIF2S11
NM_002438MRC11
NM_001009567MRC1L11
NM_000950PRRG11
NM_004586RPS6KA31
NM_004697PRPF41
NM_177999ASB61
NM_017873ASB61
NM_013313YPEL11
NM_000232SGCB1
NM_173591C12orf641
NM_152624DCP21
NM_138815DPPA21
NM_003791MBTPS11
XM_001133421LOC7317741
XM_001132470LOC7290701
NM_006397RNASEH2A1
XM_001126144LOC7305101
XM_942958LOC6422361
XM_943005LOC6422361
NM_002009FGF71
NM_001040450FAM63B1
NM_001040453FAM63B1
NM_006421ARFGEF11
NM_022897RANBP171
NM_003617RGS51
NM_006580CLDN161
NM_001995ACSL11
NM_024099C11orf481
NM_003966SEMA5A1
XM_001127568LOC7284991
XM_001127665LOC7285261
XM_001130826LOC7284521
XM_001127715LOC7285401
XM_001127825LOC7285751
XM_001130837LOC6433671
XM_932646LOC3400891
NM_024641MANEA1
NM_014292CBX61
NM_000859HMGCR1
NM_006133DAGLA1
NM_004804CIAO11
NM_015044GGA21
XM_938689KIAA16711
XM_371461KIAA16711
NM_170774RASSF21
NM_014737RASSF21
NM_002486NCBP11
NM_053023ZFP911
NM_003392WNT5A1
NM_001001874TPD52L31
NM_001039547GK51
NM_001031748C12orf401
NM_024704C20orf231
NM_153240NPHP31
NM_006614CHL11
NM_024947PHC31
NM_001013717LOC4411081
NM_014612FAM120A1
NM_207381TNFAIP8L31
NM_144726RNF1451
NM_020974SCUBE21
NM_0010988321
NM_032837FAM104A1
NM_000916OXTR1
XM_936719LOC6476621
NM_0010122411
NM_080591PTGS11
NM_000962PTGS11
NM_015270ADCY61
NM_020983ADCY61
NM_002111HD1
NM_004185WNT2B1
NM_024494WNT2B1
NM_201624USP331
NM_015017USP331
NM_006241PPP1R21
NM_0011127411
NM_175709CBX71
NM_007264ADMR1
NM_139015SPPL31
NM_020207C9orf1021
NM_015155LARP51
NM_001012763GNRHR1
NM_000406GNRHR1
NM_138981MAPK101
NM_138982MAPK101
NM_138980MAPK101
NM_002753MAPK101
NM_177452TRAPPC6B1
NM_001079537TRAPPC6B1
NM_015090NFASC1
NM_173794FUNDC11
NM_014727MLL41
NM_017700FLJ201841
NM_003787NOL41
NM_032900ARHGAP191
XM_001127763LOC7308201
XM_001127798LOC7283811
NM_0010994551
NM_018340FLJ111511
XM_941142FTO1
NM_001080432FTO1
NM_002594PCSK21
NM_000430PAFAH1B11
NM_153262SYT141
NM_020228PRDM101
NM_199438PRDM101
NM_199437PRDM101
NM_199439PRDM101
NM_019903ADD31
NM_016824ADD31
NM_001121ADD31
XM_945000LOC6454341
XM_932897LOC6454341
NM_016480PAIP21
NM_001033112PAIP21
NM_004090DUSP31
NM_020960GPR1071
NM_014747RIMS31
NM_001010940C9orf1351
XM_938097DKFZP686C22811
XM_927469DKFZP686C22811
NM_001011537FYTTD11
NM_032288FYTTD11
NM_0209081
NM_005078TLE31
NM_0011051921
NM_001001502SNCB1
NM_003085SNCB1
NM_004064CDKN1B1
NM_015472WWTR11
NM_005318H1F01
NM_018085IPO91
NM_018687LOC559081
NM_020393PGLYRP41
XM_930349LOC6472861
XM_941201LOC6472861
NM_006246PPP2R5E1
XM_001130776LOC7296071
XM_001127132LOC7307671
NM_052978TRIM91
NM_022803UCP31
NM_003304TRPC11
NM_020429SMURF11
NM_181349SMURF11
NM_145175FAM84A1
NM_022566MESDC11
NM_018941CLN81
NM_017712PGPEP11
NM_0208461
NM_003576STK241
NM_001032296STK241
NM_006802SF3A31
NM_033661WDR41
NM_006924SFRS11
NM_001078166SFRS11
NM_014978SORCS31
NM_003146SSRP11
NM_033170B3GALT51
NM_033173B3GALT51
NM_033171B3GALT51
NM_006057B3GALT51
NM_033172B3GALT51
NM_005262GFER1
XM_942780SYNPO21
NM_014881DCLRE1A1
NM_024094DCC11
NM_0011046471
NM_018155SLC25A361
NM_032727INA1
NM_213589RAPH11
NM_024077SECISBP21
NM_152476ZNF5601
NM_0011112831
NM_207380FLJ433391
NM_152308C16orf751
NM_033083EAF11
XM_379636C9orf1221
XM_940165C9orf1221
NM_022080NAPB1
NM_021188ZNF4101
NM_0010988191
NM_0010988181
NM_000923PDE4C1
NM_181342FKBP71
NM_033027AXUD11
XM_001128616LOC4010211
NM_018012KIF26B1
NM_001024227ARF11
NM_001658ARF11
NM_001024228ARF11
NM_001024226ARF11
NM_015901NUDT131
NM_024798SNX221
NM_145762GFRA41
NM_022139GFRA41
NM_173854SLC41A11
NM_032642WNT5B1
NM_030775WNT5B1
NM_001012420GOLGA8G1
NM_001012423GOLGA8E1
NM_080668CDCA51
NM_003948CDKL21
NM_213600PLA2G4F1
NM_018032LUC7L1
NM_001080950MYO1C1
NM_033375MYO1C1
NM_001080779MYO1C1
NM_001006615WDR311
NM_145241WDR311
NM_001012361WDR311
NM_002340LSS1
NM_001945HBEGF1
XM_932353LOC6532031
NM_001001684FLJ458311
NM_203282ZNF2541
NM_152625ZNF3661
NM_207303ATRNL11
NM_033195LDHAL6B1
NM_000318PXMP31
NM_001079867PXMP31
NM_021629GNB41
NM_012064MIP1
NM_213566DFFA1
NM_033426KIAA17371
NM_025138C13orf231
NM_170719C13orf231
NM_144683DHRS131
NM_004232SOCS61
NM_021645UTP14C1
NM_003342UBE2G11
NM_013989DIO21
NM_001007023DIO21
NM_000793DIO21
NM_144984C10orf721
NM_203329CD591
NM_203331CD591
NM_203330CD591
NM_000611CD591
NM_001002800SMC41
NM_005496SMC41
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_018266TMEM39A1
NM_206853QKI1
NM_206854QKI1
NM_206855QKI1
NM_182944NIN1
NM_020853KIAA14671
NM_000454SOD11
NM_018170P15RS1
NM_004274AKAP61
NM_001032282KLF101
NM_005655KLF101
NM_004569PIGH1
NM_001040285PAPD51
NM_001040284PAPD51
NM_145206VTI1A1
NM_016048ISOC11
NM_020689SLC24A31
NM_014630ZNF5921
NM_013296GPSM21
NM_004807HS6ST11
NM_001012761RGMB1
NM_012405ICMT1
NM_002092GRSF11
NM_0010984771
NM_001031804MAF1
NM_015971MRPS71
NM_012081ELL21
NM_022151MOAP11
NM_000378WT11
NM_024424WT11
NM_024425WT11
NM_024426WT11
NM_031844HNRPU1
NM_004501HNRPU1
NM_006868RAB311
NM_145279MOBKL2C1
NM_201403MOBKL2C1
NM_020750XPO51
NM_020210SEMA4B1
NM_198925SEMA4B1
NM_001031727MGC32071
NM_032285MGC32071
NM_006718PLAGL11
NM_002656PLAGL11
NM_001080951PLAGL11
NM_001080954PLAGL11
NM_001080953PLAGL11
NM_001080956PLAGL11
NM_001080955PLAGL11
NM_001080952PLAGL11
NM_144633KCNH81
XM_932931LOC6454851
XM_944437LOC6454851
NM_145012CCNY1
NM_181698CCNY1
NM_153713LIX1L1
NM_001083625ANKRD121
NM_015208ANKRD121
NM_001009909LUZP21
NM_152774MGC420901
NM_001037339PDE4B1
NM_002600PDE4B1
NM_001037340PDE4B1
NM_001037341PDE4B1
NM_198584CA131
NM_024664PPCS1
NM_001077447PPCS1
NM_001754RUNX11
NM_001001890RUNX11
NM_000368TSC11
NM_031203HNRPM1
NM_005968HNRPM1
NM_016605FAM53C1
XM_001132378PTP4A21
XM_001132367PTP4A21
XM_001132372PTP4A21
XM_001132369PTP4A21
XM_001132357PTP4A21
NM_201280MUTED1
NM_203403C9orf1501
NM_0321101
NM_001032380RHOBTB11
NM_198225RHOBTB11
NM_014836RHOBTB11
NM_002332LRP11
NM_145918CTSL11
NM_001912CTSL11
NM_014028OSTM11
NM_001039649ZMYM51
NM_000437PAFAH21
NM_032574LOC846611
NM_017952PTCD31
NM_020870SH3RF11
NM_002221ITPKB1
NM_017651AHI11
NM_000551VHL1
NM_198156VHL1
NM_004972JAK21
NM_005795CALCRL1
NM_020652ZNF286A1
NM_017641KIF21A1
NM_014333CADM11
NM_0010985171
XM_943355LOC3889231
XM_373973LOC3889231
NM_001310CREBL21
NM_173665C5orf361
NM_004852ONECUT21
NM_004734DCLK11
NM_139279MCFD21
NM_005831CALCOCO21
XM_001131507LOC7298501
XM_001127610LOC7308811
NM_004364CEBPA1
NM_152667NANP1
NM_021814ELOVL51
NM_201253CRB11
NM_018228C14orf1151
NM_153268PLCXD21
NM_203372ACSL31
NM_004457ACSL31
NM_005684GPR521
NM_018387STRBP1
NM_000807GABRA21
NM_139012MAPK141
NM_139014MAPK141
NM_001315MAPK141
NM_152374FLJ389841
XM_001126406LOC7279221
XM_001126391LOC7279221
XM_001126417LOC7279221
NM_054016FUSIP11
NM_133334WHSC11
NM_001029884PLEKHG11
NM_003672CDC14A1
XM_940314NLF21
NM_001030055ARHGAP51
NM_001173ARHGAP51
NM_015272KIAA10051
NM_001167BIRC41
NM_153427PITX21
NM_000325PITX21
NM_153426PITX21
NM_001029996MGC336571
NM_032352BRMS1L1
NM_006587CORIN1
NM_016308CMPK1
NM_145284FAM122B1
NM_016467ORMDL11
NM_145735ARHGEF71
NM_182641BPTF1
NM_004459BPTF1
NM_012416RANBP61
NM_174934SCN4B1
NM_014319LEMD31
NM_006273CCL71
NM_181783TMTC31
NM_001080534UNC13C1
XM_941380UNC13C1
NM_016281TAOK31
NM_001010891MTX31
NM_001079673FNDC3A1
NM_014923FNDC3A1
NM_198513PHF20L11
NM_001621AHR1
NM_002247KCNMA11
NM_015726WDR42A1
NM_181523PIK3R11
NM_181504PIK3R11
NM_181524PIK3R11
NM_020731AHRR1
NM_152571C9orf1631
NM_012129CLDN121
NM_194318B3GALTL1
NM_006734HIVEP21
NM_194439RNF2121
NM_145650MUC151
NM_152678FAM116A1
XM_001132771FAM116A1
NM_002055GFAP1
NM_024577SH3TC21
NM_080616C20orf1121
NM_001001586ATP1A11
NM_145693LPIN11
NM_001005502CPM1
NM_198320CPM1
NM_001874CPM1
NM_0152071
NM_013443ST6GALNAC61
NM_006922SCN3A1
NM_001081677SCN3A1
NM_001081676SCN3A1
NM_003189TAL11
NM_003971SPAG91
NM_0333901
NM_013256ZNF1801
NM_002877RAD51L11
NM_014830ZBTB391
NM_144632TMEM1821
NM_004588SCN2B1
NM_032807FBXO181
NM_178150FBXO181
NM_004067CHN21
NM_001039936CHN21
NM_181655C17orf581
NM_181656C17orf581
NM_173687C8orf311
NM_001009555SH3D191
NM_152695ZNF4491
XM_001128311LOC7314491
XM_001129750LOC7289991
NM_153711FAM26E1
NM_001001396ATP2B41
NM_001684ATP2B41
NM_004349RUNX1T11
NM_175634RUNX1T11
NM_175635RUNX1T11
NM_175636RUNX1T11
NM_020714ZNF4901
NM_005536IMPA11
NM_000689ALDH1A11
XM_001133760ZNF5191
NM_003139SRPR1
NM_017855ODAM1
NM_030583MATN21
NM_002380MATN21
NM_002487NDN1
NM_0011001621
NM_0011001611
NM_015024XPO71
NM_022726ELOVL41
NM_007047BTN3A21
NM_002187IL12B1
NM_005879TRAIP1
NM_024619FN3KRP1
NM_015030FRYL1
NM_030964SPRY41
NM_001039618CREBZF1
NM_024325ZNF3431
NM_021141XRCC51
NM_172128CAMK2D1
NM_172127CAMK2D1
NM_145052UPRT1
NM_017813IMPAD11
NM_016356DCDC21
NM_031314HNRPC1
NM_001077443HNRPC1
NM_001077442HNRPC1
NM_004500HNRPC1
NM_000141FGFR21
NM_022970FGFR21
NM_052932TMEM1231
NM_014112TRPS11
NM_019027FLJ202731
NM_0010986341
NM_001077401ACVRL11
NM_000020ACVRL11
NM_024646ZYG11B1
NM_030643APOL41
NM_145660APOL41
NM_007011ABHD21
NM_152924ABHD21
XM_942240LOC6505571
NM_001080140CT47.71
NM_001080139CT47.81
NM_001080141CT47.61
NM_001080142CT47.51
NM_001080143CT47.41
NM_001080146CT47.11
NM_001080145CT47.21
NM_001080138CT47.91
NM_001080137CT47.101
NM_001080144CT47.31
NM_173571CT47.111
NM_0010996451
NM_052918SORCS11
NM_001013031SORCS11
NM_032809FAM73B1
NM_004537NAP1L11
NM_139207NAP1L11
NM_001146ANGPT11
NM_152264SLC39A131
NM_003693SCARF11
NM_145351SCARF11
NM_145350SCARF11
NM_145349SCARF11
NM_145352SCARF11
NM_021912GABRB31
NM_000814GABRB31
NM_000256MYBPC31
NM_022648TNS11
NM_015197PACS21
NM_0011009131
NM_017545HAO11
NM_000115EDNRB1
NM_182522FAM19A41
NM_001005527FAM19A41
NM_024620ZNF3291
NM_003488AKAP11
NM_012345NUFIP11
NM_016623FAM49B1
XM_001132495SLC26A111
NM_173626SLC26A111
XM_937397ANKRD311
XM_927671ANKRD311
NM_032342C9orf1251
NM_198392TCF211
NM_0010096101
NM_198552FAM89A1
NM_198859PRICKLE21
NM_198503KCNT21
XM_001125986LOC2838241
NM_022166XYLT11
NM_016353ZDHHC21
NM_014915ANKRD261
NM_022048CSNK1G11
NM_000259MYO5A1
NM_0146951
NM_019844SLCO1B31
NM_007006NUDT211
NM_024692CLIP41
NM_005596NFIB1
NM_178584SEPT101
NM_144710SEPT101
NM_001201BMP31
NM_020728FAM62B1
NM_022824FBXL171
NM_024017HOXB91
NM_024855ACTR51
NM_052965C1orf191
NM_144575CAPN131
NM_001037171ACOT91
NM_001033583ACOT91
NM_203376TMEM811
NM_181701QSOX21
NM_018293ZNF6541
XM_001126706ZNF6541
NM_000929PLA2G51
NM_0011096621
NM_024948C10orf971
NM_016075VPS361
NM_020935USP371
NM_017655GIPC21
NM_001040152PEG101
NM_014264PLK41
NM_199423WWP21
NM_018639WSB21
NM_002508NID11
NM_020353PLSCR41
NM_152221CSNK1E1
NM_001894CSNK1E1
NM_001004342TRIM671
NM_001014380KATNAL11
NM_032116KATNAL11
NM_000237LPL1
NM_001007525NWD11
NM_014379KCNV11
NM_0011045441
NM_0011045451
NM_017938FAM70A1
NM_032333C10orf581
XM_945770LOC1458371
XM_370871LOC1458371
NM_080876DUSP191
NM_002709PPP1CB1
NM_206876PPP1CB1
NM_003705SLC25A121
NM_022041GAN1
NM_018975TERF2IP1
NM_173509C1orf761
NM_0208271
NM_003588CUL4B1
NM_001079872CUL4B1
NM_005239ETS21
NM_052950WDFY21
NM_001042751STAG21
NM_001042750STAG21
NM_001042749STAG21
NM_006603STAG21
NM_021167GATAD11
NM_024640YRDC1
NM_144644SPATA41
NM_012164FBXW21
NM_173654C3orf641
NM_001079512LOC7807761
NM_203307ZNF3211
NM_001025369VEGFA1
NM_001033756VEGFA1
NM_001025370VEGFA1
NM_001025368VEGFA1
NM_001025366VEGFA1
NM_001025367VEGFA1
NM_003376VEGFA1
NM_006996SLC19A21
NM_001776ENTPD11
NM_0010981751
NM_002234KCNA51
NM_016083CNR11
NM_033181CNR11
NM_016929CLIC51
NM_014071NCOA61
NM_015975TAF9B1
XM_001126120LOC7281981
NM_005748YAF21
NM_016087WNT161
NM_057168WNT161
NM_022112P53AIP11
NM_019021C11orf711
NM_023112OTUB21
NM_032801JAM31
NM_030806C1orf211
XM_001126223LOC7305151
XM_001127751LOC7284931
NM_001024649CANX1
NM_001746CANX1
NM_199286DPPA31
NM_001004317LIN28B1
NM_025076UXS11
NM_003193TBCE1
NM_001079515TBCE1
NM_032573CCDC621
NM_016206VGLL31
NM_001013657LOC3906371

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317