Predicted Off-targets for siRNA "ggauccucaacucacucuu" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

13 hits were found for GGAUCCUCAACUCACUCUU (6 guide strand hits and 7 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_079422 MYL1 16 34 cagcCCUCAACUCACUCUU30 4 15 bc false   <90%   862
NM_182642 CTDSP1 110 128 GcAUCCUCcACUCACUCUU28 2 10 bc false   <90%   783
NM_021198 CTDSP1 446 464 GcAUCCUCcACUCACUCUU28 2 10 bc false   <90%   2655
NM_080669 SLC46A1 1319 1337 GcAUCuUCAACUCACUCUa20 3 12 bc false   <90%   6505
XM_941352 LOC255275 1515 1533 caAUCCcCAACUCACUCUc15 4 11 bc false   <90%   3042
XM_171855 LOC255275 1515 1533 caAUCCcCAACUCACUCUc15 4 11 bc false   <90%   3042


Hits to Sense strand








AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_015077 SARM1 6507 6525 uAGAGUGAGUUGAaGAUgC75 3 12 c false   <90%   6862
XM_001130643 LOC729568 445 463 AAGAGUGAGUUGAuGAaCg51 3 13 c false   <90%   720
XR_019433 LOC651669 478 496 AAGAGUGAGUUGAuGAaCg51 3 13 c false   <90%   812
XR_015550 LOC729450 888 906 AAGAGUGAGUUGAuGAaCg51 3 13 c false   <90%   1222
NM_001004478 OR10Z1 582 600 ccGAGUGAGcUGAGGAUCu-1 4 8 bc false   <90%   942
XM_001128780 LOC730991 1614 1632 ggcAGUGAGaUGAGGAUCC-15 4 9 bc false   <90%   2213
XM_001126745 LOC728061 1615 1633 ggcAGUGAGaUGAGGAUCC-15 4 9 bc false   <90%   2215


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1482
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_024103SLC25A238
NM_020844KIAA14563
NM_0010996773
NM_020526EPHA83
NM_020443NAV13
NM_014730KIAA01523
NM_032966BLR12
NM_001716BLR12
NM_001018065NTRK22
NM_001018066NTRK22
NM_005399PRKAB22
NM_175736FMNL32
NM_198900FMNL32
NM_012334MYO102
NM_0153512
NM_001042599ERBB42
NM_005235ERBB42
XM_934649C1orf342
XM_945958C1orf342
NM_181489ZNF4452
NM_001025109CD342
NM_001773CD342
NM_006375ENOX22
NM_182314ENOX22
NM_033631LUZP12
NM_001008493ENAH2
NM_018212ENAH2
NM_000167GK2
NM_203391GK2
NM_032800C1orf1982
NM_017633FAM46A2
NM_024958NRSN22
NM_006926SFTPA22
NM_0010986682
NM_002204ITGA32
NM_005501ITGA32
NM_0011013872
NM_001039479KIAA03172
NM_172101CD8B2
XM_944835LOC6486912
NM_012316KPNA62
NM_022377ICAM42
NM_006729DIAPH22
NM_0010998542
NM_0010246612
NM_001001685FLJ450792
NM_001039199C20orf1212
NM_024331C20orf1212
NM_014760TATDN22
NM_000695ALDH3B22
NM_001031615ALDH3B22
NM_032105PPP1R12B2
NM_002481PPP1R12B2
NM_001002860BTBD72
NM_014764DAZAP22
NM_002501NFIX2
NM_001039355SLC25A292
NM_001004354MGC615982
NM_000259MYO5A2
NM_017623CNNM32
NM_199078CNNM32
NM_031490LONP22
NM_000875IGF1R2
NM_022112P53AIP12
NM_002688SEPT52
NM_021116ADCY12
NM_006037HDAC42
NM_005957MTHFR2
NM_033419PERLD12
NM_024590ARSJ2
XM_001131395LOC7298102
XM_001126629LOC7306342
NM_198468C6orf1672
NM_025239PDCD1LG22
NM_138809CMBL2
NM_001008709PPP1CA2
NM_206873PPP1CA2
NM_002708PPP1CA2
NM_181654CPLX42
NM_014909VASH12
NM_006814PSMF12
NM_178578PSMF12
NM_020458TTC7A2
NM_005547IVL1
NM_0207211
NM_021912GABRB31
NM_000814GABRB31
NM_000498CYP11B21
NM_130847AMOTL11
XM_001131042LOC7318521
NM_138413C10orf651
XM_001134400LOC7302581
XM_001133989LOC7297701
XM_001132966LOC7311641
NM_001863COX6B11
NM_020766PCDH191
NM_0011052431
NM_032107L3MBTL1
NM_015478L3MBTL1
NM_152749ATXN7L41
NM_144964RG9MTD31
NM_0011099741
NM_133468BMPER1
NM_052811TRIM131
NM_213590TRIM131
NM_001007278TRIM131
NM_005798TRIM131
NM_016032ZDHHC91
NM_001008222ZDHHC91
NM_014321ORC6L1
NM_002069GNAI11
NM_021913AXL1
NM_001699AXL1
NM_015634KIAA12791
NM_031445AMMECR1L1
NM_001040661SLC29A41
NM_153247SLC29A41
NM_198597SEC24C1
NM_004922SEC24C1
NM_003826NAPG1
NM_021192HOXD111
NM_001080412ZBTB381
XM_001133510ZBTB381
NM_001005210LRRC551
NM_002206ITGA71
NM_005707PDCD71
NM_004078CSRP11
NM_207395ZNF324B1
NM_015719COL5A31
NM_014926SLITRK31
NM_003913PRPF4B1
NM_007256SLCO2B11
NM_0121941
NM_005578LPP1
NM_152765C8orf461
NM_013255MKLN11
NM_152291MUC71
NM_007231SLC6A141
NM_015995KLF131
NM_001080975REPS21
NM_004726REPS21
NM_172244SGCD1
NM_080872UNC5D1
XM_945000LOC6454341
XM_932897LOC6454341
NM_173474NTAN11
NM_015047KIAA00901
NM_001014380KATNAL11
NM_032116KATNAL11
NM_000338SLC12A11
NM_025027ZNF6061
NM_006402HBXIP1
NM_173483FLJ395011
NM_012388PLDN1
NM_001037339PDE4B1
NM_002600PDE4B1
NM_001037340PDE4B1
NM_001037341PDE4B1
NM_016413CPB21
NM_001872CPB21
NM_181809BMP8A1
NM_000979RPL181
XM_001126406LOC7279221
XM_001126391LOC7279221
XM_001126417LOC7279221
NM_001806CEBPG1
NM_130853PTPRS1
NM_002850PTPRS1
NM_130855PTPRS1
NM_130854PTPRS1
NM_138417KTI121
NM_138395MARS21
NM_020377CYSLTR21
NM_015385SORBS11
NM_001034954SORBS11
NM_001034957SORBS11
NM_001034955SORBS11
NM_001034956SORBS11
NM_006434SORBS11
NM_024991SORBS11
XM_932025LOC6441711
XM_944971LOC6441711
NM_001042697ZSWIM71
NM_001042698ZSWIM71
NM_004551NDUFS31
NM_178844NLRC31
NM_004958FRAP11
NM_199191BRE1
NM_199193BRE1
NM_004899BRE1
NM_199194BRE1
NM_199192BRE1
NM_025230WDR231
NM_181357WDR231
NM_032859ABHD131
NM_023935C20orf1161
NM_145266NUDCD21
NM_005596NFIB1
NM_006361HOXB131
NM_003485GPR681
NM_018590GALNACT-21
NM_012309SHANK21
NM_002928RGS161
NM_153427PITX21
NM_000325PITX21
NM_153426PITX21
NM_015346ZFYVE261
NM_017547FOXRED11
XM_939186GPSM11
NM_152222TNFRSF19L1
NM_032871TNFRSF19L1
NM_005149TBX191
NM_203451LOC4001201
NM_006774INMT1
NM_017811UBE2R21
NM_012224NEK11
NM_147192DMBX11
NM_172225DMBX11
NM_020381PDSS21
NM_024052C17orf391
NM_001002909GPATCH81
NM_021830PEO11
NM_001047605KIR3DX11
NM_030981RAB1B1
NM_024996GFM11
NM_170740ALDH5A11
NM_001080ALDH5A11
NM_020834HOMEZ1
NM_1522931
NM_138817SLC7A131
NM_052868IGSF81
NM_1942941
NM_005511MLANA1
NM_030817APOLD11
NM_152344LSM121
XM_940069PPP1R3E1
XM_927029PPP1R3E1
NM_182907PRDM11
NM_001198PRDM11
NM_001304CPD1
NM_022081HPS41
NM_152841HPS41
NM_006691XLKD11
NM_025125C10orf571
NM_015107PHF81
NM_030907C1orf891
NM_006581FUT91
NM_004736XPR11
NM_012384GMEB21
NM_001336CTSZ1
NM_002118HLA-DMB1
NM_178006STARD131
NM_178007STARD131
NM_052851STARD131
NM_003128SPTBN11
NM_001034845GALNT171
NM_000230LEP1
NM_001560IL13RA11
NM_002006FGF21
NM_033305VPS13A1
NM_001018037VPS13A1
NM_003156STIM11
NM_001419ELAVL11
NM_031471URP21
XM_001131186LOC7297461
NM_001080745DGKG1
NM_001346DGKG1
NM_001080744DGKG1
NM_015975TAF9B1
XM_001126120LOC7281981
NM_022473ZFP1061
NM_004624VIPR11
NM_138694PKHD11
NM_001944DSG31
NM_006380APPBP21
NM_003417ZNF2641
NM_012100DNPEP1
NM_020947KIAA16091
XM_001130546LOC7295421
NM_001007536AKR1CL11
NM_182705FAM101B1
NM_021013KRT341
NM_015155LARP51
NM_005316GTF2H11
NM_024699ZFAND11
NM_005231CTTN1
NM_138565CTTN1
NM_006885ATBF11
NM_004983KCNJ91
NM_001009616SPANXN51
NM_015056RRP1B1
NM_003227TFR21
NM_152429FGFBP31
NM_006133DAGLA1
NM_021809TGIF21
NM_080670SLC35A41
NM_152307C14orf1721
NM_0011107811
NM_001002034FAM109B1
NM_004308ARHGAP11
NM_001859SLC31A11
NM_006096NDRG11
NM_203404AMPD21
NM_139156AMPD21
NM_004037AMPD21
NM_014586HUNK1
NM_052848CCDC971
NM_015458MTMR91
XM_001126091LOC7304961
NM_030927TSPAN141
NM_025268TMEM1211
XM_001128242LOC7287041
XM_001128273LOC7287191
NM_001042432CLN31
NM_000086CLN31
NM_017857SSH31
NM_024837ATP8B41
NM_015079TBC1D2B1
NM_0011016761
NM_020814MARCH41
NM_004556NFKBIE1
NM_198491FAM92B1
NM_006184NUCB11
NM_152420C9orf411
NM_004091E2F21
NM_006939SOS21
NM_006206PDGFRA1
NM_198392TCF211
NM_004852ONECUT21
NM_001219CALU1
NM_003099SNX11
NM_152826SNX11
NM_148955SNX11
NM_000530MPZ1
XM_001134002C17orf411
NM_153615Rgr1
NM_001042383CEP631
NM_001042400CEP631
NM_025180CEP631
NM_015044GGA21
XM_928029RNF1871
XM_001129309RNF1871
XM_001132901LOC7302001
XM_001133006LOC7323681
NM_018344SLC29A31
NM_002599PDE2A1
NM_024624SMC61
NM_052918SORCS11
NM_001013031SORCS11
NM_003121SPIB1
NM_001875CPS11
NM_138300PYGO21
NM_0330261
NM_015726WDR42A1
NM_006191PA2G41
NM_005877SF3A11
NM_001005409SF3A11
XM_001125753MUC3B1
NM_032810ATAD11
NM_001018000KIAA10261
NM_001017999KIAA10261
NM_001018001KIAA10261
NM_015209KIAA10261
NM_000272NPHP11
NM_002375MAP41
NM_030884MAP41
NM_004554NFATC41
NM_020917ZFP141
XM_929032LOC6460711
XM_001125928LOC2838041
XM_001126277LOC6489131
NM_182578THEM51
NM_133367PAQR81
NM_144997FLCN1
NM_138700TRIM401
NM_015227POFUT21
NM_133634POFUT21
NM_133635POFUT21
NM_001012710KRTAP5-101
NM_002996CX3CL11
NM_0207091
NM_173578C11orf721
NM_199246CCNG11
NM_004060CCNG11
NM_001719BMP71
NM_030576LIMD21
NM_172213CD8B1
NM_172102CD8B1
NM_005789PSME31
NM_176863PSME31
NM_017850C1orf1091
NM_207333ZNF3201
NM_173547TRIM651
NM_020698TMCC31
NM_175861TMTC11
NM_001044387ZNF5571
NM_024341ZNF5571
NM_001044388ZNF5571
NM_022755IPPK1
NM_015645C1QTNF51
NM_001079843CASZ11
NM_133334WHSC11
NM_207111TRIAD31
NM_207116TRIAD31
NM_178129P2RY81
NM_001013615C1orf1901
NM_001695ATP6V1C11
NM_001042633SNX211
NM_033421SNX211
NM_001042632SNX211
NM_152897SNX211
NM_001188BAK11
NM_001024960ARPC41
NM_005718ARPC41
NM_001024959ARPC41
NM_001759CCND21
NM_0011052471
NM_024742ARMC51
NM_005779LHFPL21
NM_015559SETBP11
NM_001012508SPRN1
XM_001126273LOC7277731
XM_941026ING51
NM_032329ING51
NM_171982TRIM351
NM_017765PQLC21
NM_001040126PQLC21
NM_001040125PQLC21
NM_001407CELSR31
NM_025194ITPKC1
NM_207390FLJ459101
NM_183238ZNF6051
NM_005431XRCC21
NM_005551KLK21
NM_001002231KLK21
NM_014734KIAA02471
XM_001126066LOC7304971
NM_181521CMTM41
NM_012137DDAH11
NM_005940MMP111
NM_030767AKNA1
NM_001003760KLHL311
NM_001010866RP13-15M17.21
NM_176816CCDC1251
NM_018178GOLPH3L1
NM_020964KIAA16321
NM_000342SLC4A11
NM_016219MAN1B11
NM_001004325KRTAP5-21
NM_030918SNX271
NM_031450C11orf681
NM_138287DTX3L1
NM_018234STEAP31
NM_001008410STEAP31
NM_182915STEAP31
NM_000219KCNE11
NM_000074CD40LG1
NM_004124GMFB1
NM_152793C7orf411
NM_203454APOBEC41
NM_006334OLFM11
NM_152860SP71
NM_130809PRRC11
NM_033397KIAA17541
NM_001080453INTS11
XM_935548INTS11
XM_942544INTS11
NM_181877ZSCAN21
NM_001080457LRRC4B1
XM_936789LRRC4B1
NM_003311PHLDA21
NM_198183UBE2L61
NM_004223UBE2L61
XM_929902LOC6469381
XM_937239LOC6481891
XM_001130722LOC7317691
XM_001127289LOC7283531
NM_003264TLR21
NM_017668NDE11
NM_018106ZDHHC41
NM_007189ABCF21
NM_173477USH1G1
NM_001009922RCHY11
NM_001008925RCHY11
NM_015436RCHY11
XM_001133221LOC7302411
NM_181502SPINLW11
NM_020398SPINLW11
NM_032039ITFG31
NM_032295SLC37A31
NM_207113SLC37A31
NM_002862PYGB1
NM_0011008291
NM_198482SH2D61
NM_001005786DAZ21
NM_020420DAZ41
NM_001005375DAZ41
NM_004081DAZ11
NM_020364DAZ31
NM_020363DAZ21
NM_001005785DAZ21
XM_001126098LOC6530751
NM_013994DDR11
NM_013993DDR11
NM_001954DDR11
NM_004613TGM21
NM_005937MLLT61
NM_015329KIAA08921
NM_006465ARID3B1
NM_015278SASH11
NM_001013690LOC4017201
NM_021046KRTAP5-81
NM_015092SMG11
NM_0010997331
NM_001117ADCYAP11
NM_183425RBM381
NM_017495RBM381
NM_176072P2RY21
NM_002564P2RY21
NM_176071P2RY21
XM_932931LOC6454851
XM_944437LOC6454851
NM_004323BAG11
NM_006393NEBL1
NM_024738C12orf491
NM_002030FPRL21
NM_003983SLC7A61
NM_001076785SLC7A61
NM_182898CREB51
NM_004904CREB51
NM_001011666CREB51
NM_182899CREB51
NM_0011003891
NM_014096SLC43A31
NM_199329SLC43A31
NM_017611SLC43A31
NM_015557CHD51
NM_018294CWF19L11
NM_001080519BAHCC11
XM_001134463BAHCC11
NM_206925CA121
NM_001218CA121
NM_001002762DNAJB121
NM_017626DNAJB121
NM_024979MCF2L1
NM_0011127321
NM_014080DUOX21
NM_020433JPH21
NM_014935PLEKHA61
NM_152743C7orf271
NM_033386MICALL11
NM_173653SLC9A91
NM_014850SRGAP31
NM_001033117SRGAP31
NM_004612TGFBR11
NM_0011111131
NM_005339HIP21
NM_0011111121
NM_203458NOTCH2NL1
NM_001008390CGGBP11
NM_003663CGGBP11
NM_024607PPP1R3B1
NM_058246DNAJB61
NM_153188TNPO11
NM_002270TNPO11
NM_018982YIPF11
NM_0010981991
NM_005279GPR11
NM_001014442PCOTH1
NM_023007JMJD41
NM_016376ANKFY11
NM_014363SACS1
XM_945588FLJ303751
XM_498945FLJ303751
NM_016577RAB6B1
XM_001131300LOC1491571
XM_001132625LOC1491571
NM_020960GPR1071
NM_004187JARID1C1
NM_017705PAQR51
NM_0011045541
NM_024097C1orf501
NM_182511CBLN21
NM_006863LILRA11
NM_080820DTD11
NM_003825SNAP231
NM_130798SNAP231
NM_001029861NANOS21
NM_016087WNT161
NM_057168WNT161
NM_001042552TATDN31
NM_001042553TATDN31
NM_003200TCF31
XM_209227LOC6534641
NM_023934FUNDC21
NM_002350LYN1
NM_0011110971
XM_943323LOC6467191
XM_933842LOC6467191
NM_017650PPP1R9A1
NM_178500PHOSPHO11
NM_080876DUSP191
XM_001131408LOC7303501
XM_001127666LOC7308961
NM_153450MED191
NM_001044392MUC11
NM_001044390MUC11
NM_001044393MUC11
NM_001044391MUC11
NM_001018017MUC11
NM_001018016MUC11
NM_002456MUC11
NM_005188CBL1
NM_001013439FXR11
NM_001013438FXR11
NM_005087FXR11
NM_173602DIP2B1
NM_152470RNF1651
NM_015291DNAJC161
NM_020704FAM40B1
XM_943193LOC4000271
XM_931434LOC4000271
NM_014454SESN11
NM_014925R3HDM21
NM_181553CMTM31
NM_001048251CMTM31
NM_181554CMTM31
NM_144601CMTM31
NM_000226KRT91
NM_017684VPS13C1
NM_020821VPS13C1
NM_017849TMEM1271
NM_003098SNTA11
NM_0010976201
XM_001131851LOC6490951
XM_001132597LOC6442351
NM_015894STMN31
NM_145279MOBKL2C1
NM_201403MOBKL2C1
NM_005630SLCO2A11
NM_001003940BMF1
NM_001003943BMF1
NM_001003942BMF1
NM_033503BMF1
NM_033100PCDH211
NM_033048CPXCR11
NM_005329HAS31
NM_031282FCRL41
NM_015259ICOSLG1
NM_001032394GPR1261
NM_020455GPR1261
NM_198569GPR1261
NM_001032395GPR1261
NM_199342CCDC231
NM_003393WNT8B1
NM_006444SMC21
NM_001042550SMC21
NM_001042551SMC21
NM_014361CNTN51
NM_175566CNTN51
NM_024677NSUN71
NM_007325GRIA31
NM_000828GRIA31
NM_178349LCE1B1
NM_007050PTPRT1
NM_133170PTPRT1
NM_016395PTPLAD11
XM_001133298LOC7324021
NM_002872RAC21
NM_004265FADS21
NM_018593SLC16A101
NM_006319CDIPT1
NM_020137GRIPAP11
NM_016458C8orf30A1
XM_001126758LOC7280711
XM_943073LOC6478691
XM_927767LOC6535051
XM_928338LOC6535981
XM_927706LOC6445911
NM_019089HES21
NM_003811TNFSF91
NM_203290POLR1C1
NM_001029858SLC35F11
NM_030967KRTAP1-11
XM_001128870LOC7289461
NM_000721CACNA1E1
NM_178428LCE2A1
NM_144575CAPN131
NM_032563LCE3D1
NM_004385VCAN1
NM_0010994041
NM_198056SCN5A1
NM_0010994051
NM_000335SCN5A1
XM_001129732FLJ226591
XM_001133602LOC3884361
NM_002355M6PR1
XM_375443LOC2841001
NM_176787PIGN1
NM_012327PIGN1
NM_007195POLI1
NM_032104PPP1R12B1
NM_032103PPP1R12B1
NM_018940PCDHB71
NM_018667SMPD31
NM_002025AFF21
NM_207429FLJ458031
NM_001831CLU1
NM_203339CLU1
NM_000266NDP1
XM_001131068LOC7296961
XM_001129643LOC7314351
NM_017656ZNF5621
NM_152289ZNF5611
NM_025010KLHL181
NM_001004342TRIM671
NM_012264C22orf51
NM_207514FLJ201861
NM_015630EPC21
NM_032506KIAA18411
NM_016592GNAS1
NM_001077490GNAS1
NM_145173DIRAS11
NM_198460GBP61
NM_015691WWC31
NM_144667FLJ328941
NM_001077352RBM231
NM_018107RBM231
NM_001077351RBM231
NM_004287GOSR21
NM_001029883FLJ349311
NM_020676ABHD61
NM_006640SEPT91
XM_290799ARHGAP231
NM_153487MDGA11
NM_178126LOC1624271
NM_003145SSR21
XM_001128341SSR21
NM_020643C11orf161
NM_001496GFRA31
NM_014655SLC25A441
NM_152367C1orf1611
NM_175039ST6GALNAC41
NM_175040ST6GALNAC41
NM_018715RCC21
NM_000499CYP1A11
NM_014911AAK11
NM_173495PTCHD11
NM_002842PTPRH1
NM_001013635LOC3878561
XM_001128921LOC3878561
NM_133448TMEM132D1
NM_005245FAT1
NM_001748CAPN21
NM_001077663URG41
NM_017920URG41
NM_001077664URG41
NM_001003674C18orf11
NM_181483C18orf11
NM_181481C18orf11
NM_001003675C18orf11
NM_004338C18orf11
NM_181482C18orf11
NM_003034ST8SIA11
NM_020784KIAA13441
XM_001128649LOC7288901
XM_001125920LOC7278561
XM_376814MGC130051
NM_032664FUT101
NM_004584RAD9A1
NM_005978S100A21
NM_015082FSTL41
NM_001043SLC6A21
NM_018207TRIM621
NM_001003891PCQAP1
NM_015889PCQAP1
NM_014225PPP2R1A1
NM_003670BHLHB21
NM_000334SCN4A1
NM_153636CPNE71
NM_014427CPNE71
NM_014826CDC42BPA1
NM_003607CDC42BPA1
NM_002632PGF1
NM_018202TMEM571
NM_033508GCK1
NM_033507GCK1
NM_000162GCK1
NM_003108SOX111
NM_015090NFASC1
NM_001004302ZNF7831
NM_018655LENEP1
NM_006496GNAI31
NM_015247CYLD1
NM_001042412CYLD1
NM_001042355CYLD1
NM_152309PIK3AP11
NM_013402FADS11
XM_001131577FLJ366441
XM_001126095FLJ366441
NM_006995BTN2A21
NM_181531BTN2A21
NM_017670OTUB11
NM_020530OSM1
NM_014871USP521
NM_006371CRTAP1
NM_001264CDSN1
NM_080429AQP101
NM_153812PHF131
NM_152253CHKB1
NM_198490RAB431
NM_001045478LOC6449971
NM_0011055631
NM_019052CCHCR11
NM_0011055641
NM_022482GZF11
NM_020428SLC44A21
NM_024900PHF171
NM_000674ADORA11
NM_001048230ADORA11
NM_014726TBKBP11
NM_021931DHX351
NM_025015HSPA12A1
NM_000361THBD1
NM_005419STAT21
NM_007030TPPP1
NM_002278KRT321
NM_004100EYA41
NM_172105EYA41
NM_172103EYA41
NM_016263FZR11
NM_000834GRIN2B1
NM_024701ASB131
NM_014949KIAA09071
NM_198153TREML41
NM_001014797KCNMA11
NM_020824ARHGAP211
NM_130468CHST141
XM_001130204LOC7303971
XM_001131359LOC7304061
XM_001130923LOC7296531
XM_001131323LOC7319341
NM_015517MIZF1
NM_198971MIZF1
NM_022897RANBP171
NM_052831C6orf1921
NM_000707AVPR1B1
NM_001018050POLR3H1
NM_138338POLR3H1
NM_001018052POLR3H1
NM_177964LOC1305761
NM_005189CBX21
NM_207577MAP61
NM_178448C9orf1401
NM_015103PLXND11
NM_004209SYNGR31
NM_004573PLCB21
NM_003363USP41
NM_199443USP41
NM_017803DUS2L1
NM_002468MYD881
NM_021976RXRB1
NM_014891PDAP11
NM_173598KSR21
NM_152568NKX6-31
NM_213596FOXN41
NM_004809STOML11
NM_015174KIAA10861
NM_020447C15orf171
NM_012164FBXW21
NM_053045MGC143271
NM_001008529MXRA71
NM_198530MXRA71
NM_153712TTL1
NM_006676USP201
NM_0011103031
NM_001008563USP201
NM_178120DLX11
NM_001038493DLX11
NM_004285H6PD1
NM_023033METTL11
NM_005371METTL11
XM_932529LOC6449491
XM_943887LOC6449491
NM_015053PPFIA41
NM_015471NSL11
NM_001042549NSL11
NM_032514MAP1LC3A1
NM_181509MAP1LC3A1
NM_031890CECR61
NM_005417SRC1
NM_198291SRC1
NM_001008784CD200R21
NM_020246SLC12A91
NM_001045556SLA1
NM_006748SLA1
NM_001045557SLA1
NM_002180IGHMBP21
XM_001129321LOC4005531
XM_001132183LOC4005531
NM_004230EDG51
NM_005474HDAC51
NM_001015053HDAC51
NM_001083909GPR1231
NM_001039675UNC45A1
NM_018671UNC45A1
NM_052926PNMA51
NM_0011031511
NM_0011031501
XM_373690LOC3882821
XM_001133719LOC3882821
NM_198186ASTN21
NM_198187ASTN21
NM_014010ASTN21
NM_014742TM9SF41
NM_005479FRAT11
NM_031918KLF161
NM_033092TRIM51
NM_013305ST8SIA51
NM_001412EIF1AX1
NM_014437SLC39A11
NM_0010937251
NM_153838GPR1151
NM_016821OGG11
NM_016828OGG11
NM_016829OGG11
NM_016826OGG11
NM_016827OGG11
NM_015481ZNF3851
NM_014646LPIN21
NM_139199BRD81
NM_012308FBXL111
NM_002469MYF61
NM_012435SHC21
NM_147188FBXO221
NM_139075TPCN21
NM_001012720RGR1
NM_002921RGR1
NM_001012722RGR1
NM_022826MARCH71
NM_020980AQP91
XM_941807NHSL11
XM_496826NHSL11
NM_003955SOCS31
NM_148170CTSC1
NM_000555DCX1
NM_178152DCX1
NM_178153DCX1
NM_178151DCX1
NM_001039904FLJ448381
NM_003155STC11
NM_017457PSCD21
NM_004228PSCD21
NM_024700SNIP11
XM_001127312LOC7283601
XM_001129734LOC7314601
NM_006428MRPL281
NM_003596TPST11
NM_000807GABRA21
NM_181535KRT281
NM_005002NDUFA91
NM_0010853541
XM_001127087FLJ439501
NM_015002FBXO211
NM_033624FBXO211
NM_020405PLXDC11
NM_001300KLF61
NM_173536GABRG11
NM_213589RAPH11
NM_175066DDX511
XM_001127975FAM66C1
NM_001017440CALN11
NM_031468CALN11
NM_001033930UBA521
NM_003333UBA521
NM_000918P4HB1
NM_207122EXT21
NM_000401EXT21
NM_0011096601
NM_0011096591
NM_173650DNAJC5G1
NM_031949TTLL21
NM_005052RAC31
NM_004210NEURL1
NM_018553C17orf851
XM_001133830LOC7295191
XM_001134313LOC7322911
NM_000510FSHB1
NM_001018080FSHB1
NM_020993BCL7A1
NM_001024808BCL7A1
NM_014256B3GNT31
NM_175932PSMD131
NM_002817PSMD131
NM_006888CALM11
NM_207362MGC423671
NM_018899PCDHAC21
NM_018900PCDHA11
NM_018902PCDHA111
NM_031849PCDHA61
NM_018905PCDHA21
NM_018904PCDHA131
NM_031860PCDHA101
NM_018907PCDHA41
NM_018909PCDHA61
NM_018910PCDHA71
NM_018911PCDHA81
NM_018906PCDHA31
NM_018903PCDHA121
NM_018898PCDHAC11
NM_031857PCDHA91
NM_031411PCDHA11
NM_018908PCDHA51
NM_018901PCDHA101
NM_031281FCRL51
NM_004564PET112L1
NM_002310LIFR1
NM_001277CHKA1
NM_212469CHKA1
NM_182509THSD31
NM_004394DAP1
NM_178128FADS61
NM_133493CD1091
NM_019616F71
NM_000131F71
NM_0011001641
NM_0011001661
NM_014721PHACTR21
NM_0011001651
NM_001001662ZNF7821
NM_032415CARD111
NM_130438DYRK1A1
NM_101395DYRK1A1
NM_130436DYRK1A1
NM_001396DYRK1A1
NM_130437DYRK1A1
NM_015284KIAA04671
NM_001010867C1orf691
NM_017714TASP11
NM_016131RAB101
NM_003299HSP90B11
NM_183061SLC9A101
NM_019044CCDC931
NM_014930ZNF5101
NM_005375MYB1
NM_014694ADAMTSL21
XM_495908DDX121
NM_004399DDX111
NM_030653DDX111
NM_153028ZNF75A1
XM_376795FLJ458721
XM_940037FLJ458721
NM_177402SYT21
NM_024652LRRK11
NM_207295MBNL11
NM_207293MBNL11
NM_207297MBNL11
NM_207296MBNL11
NM_207294MBNL11
NM_021038MBNL11
NM_207292MBNL11
NM_022495C14orf1351
NM_001007024GOSR11
NM_001007025GOSR11
NM_004871GOSR11
NM_001033047NPNT1
NM_001011513PDLIM51
NM_006457PDLIM51
NM_005984SLC25A11
NM_203329CD591
NM_203331CD591
NM_203330CD591
NM_000611CD591
NM_005867DSCR41
NM_001037954DIXDC11
NM_033425DIXDC11
NM_015469NIPSNAP3A1
NM_152622MIER31
NM_006373VAT11
NM_030796ECOP1
XM_001129280LOC7290861
XM_938287LOC6539301
NM_001008408RBM331
NM_053043PRR81
NM_015641TES1
NM_152829TES1
NM_001039966GPR301
NM_001505GPR301
NM_0010982011
NM_003947KALRN1
NM_012454TIAM21
NM_001010927TIAM21
NM_006873STON11
NM_004522KIF5C1
NM_016057COPZ11
NM_139132NUP981
NM_016320NUP981
NM_001040273TYSND11
NM_173555TYSND11
NM_014679CEP571
NM_001546ID41
NM_006420ARFGEF21
NM_005546ITK1
NM_152544C4orf231
NM_000025ADRB31
NM_152424FAM123B1
NM_017798YTHDF11
NM_024596MCPH11
NM_001381DOK11
NM_182935MOBP1
NM_016612SLC25A371
NM_002581PAPPA1
NM_015330SPECC1L1
NM_025205MED281
NM_052932TMEM1231
NM_002736PRKAR2B1
NM_017902HIF1AN1
NM_138450ARL111
NM_080654CCDC341
NM_002023FMOD1
NM_003566EEA11
NM_032051PATZ11
NM_005872BCAS21
NM_014763MRPL191
NM_130440PTPRF1
NM_002840PTPRF1
NM_030627CPEB41
NM_001010898SLC6A171
NM_018085IPO91
NM_014829DDX461
NM_006056NMUR11
NM_002698POU2F21
NM_004948DSC11
NM_024421DSC11
NM_005063SCD1
NM_007011ABHD21
NM_152924ABHD21
NM_1735951
NM_032109OTP1
NM_012197RABGAP11
NM_194452RNF1211
NM_194453RNF1211
NM_018320RNF1211
NM_005839SRRM11
NM_022367SEMA4A1
NM_052931SLAMF61
NM_003724JRK1
NM_001077527JRK1
NM_182507KRT801
NM_001081492KRT801
NM_177999ASB61
NM_017873ASB61
NM_052917GALNT131
NM_001017926ZHX11
NM_007222ZHX11
NM_003137SRPK11
NM_145727LPAL21
NM_024492LPAL21
NM_001010974BCAS41
NM_198799BCAS41
NM_017843BCAS41
NM_020957PCDHB161
NM_020778ALPK31
NM_182811PLCG11
NM_002660PLCG11
NM_013396USP251
NM_003685KHSRP1
NM_032638GATA21
XM_001128324LOC7280461
NM_015214DDHD21
NM_007188ABCB81
NM_020309SLC17A71
NM_153273IHPK11
NM_001006115IHPK11
XM_001128868LOC7312231
NM_001043318C14orf431
NM_194278C14orf431
NM_006898HOXD31
NM_024885TAF7L1
NM_020859SHROOM31
NM_032353VPS251
NM_000373UMPS1
NM_005967NAB21
XM_930431LOC6451951
XM_942574LOC6451951
XM_001129423LOC7291371
XM_001126090LOC7281461
XM_001129476LOC2864341
NM_0146431
NM_152686DNAJC181
NM_0207001
NM_003044SLC6A121
NM_001879MASP11
NM_021965PGM51
NM_0209101
XM_939770LOC6506831
XM_926711LOC6433821
NM_015140TTLL121
NM_002193INHBB1
NM_145165CHURC11
NM_014948UBOX51
NM_199415UBOX51
NM_003439ZKSCAN11
NM_023068SIGLEC11
NM_015621CCDC691
NM_032421CLIP21
NM_003388CLIP21
NM_001039585PTGFR1
NM_000959PTGFR1
NM_005981TSPAN311
NM_016065MRPS161
NM_005868BET11
NM_005392PHF21
NM_003571BFSP21
NM_017912HERC61
NM_030810TXNDC51
NM_022085TXNDC51
NM_024792FAM57A1
NM_153705KDELC21
NM_024754PTCD21
NM_198274SMYD11
NM_133330WHSC11
NM_001042424WHSC11
NM_133331WHSC11
NM_133335WHSC11
NM_006526ZNF2171
NM_001080541MGA1
XM_932727MGA1
XM_939296MGA1
XM_944092MGA1
XM_370707LOC3878901
XM_941692LOC3878901
NM_024745SHCBP11
NM_030962SBF21
NM_198843SFTPB1
NM_013446MKRN11
XM_001129047LOC7290061
XM_001130833LOC7317951
NM_016436PHF201
NM_207034EDN31
NM_000114EDN31
NM_207032EDN31
NM_207033EDN31
NM_213560PKN11
NM_002741PKN11
NM_145024CES71
NM_013252CLEC5A1
NM_022134GAL3ST21
NM_178010SOX51
NM_006940SOX51
NM_152989SOX51
NM_015075IQSEC21
NM_0011111251
NM_183337RGS111
NM_003834RGS111
NM_022746MOSC11
NM_012232PTRF1
NM_203412UBL4B1
NM_006272S100B1
NM_014862ARNT21
NM_000922PDE3B1
NM_021072HCN11
NM_001106ACVR2B1
NM_130783TSPAN181
NM_032153ZIC41
NM_017755NSUN21
NM_032168WDR751
NM_173499SPATA81
NM_001093ACACB1
NM_004723ARHGEF21
NM_198568GJB71
NM_145284FAM122B1
NM_018075TMEM16K1
XM_496115LOC4403381
XM_940659LOC4403381
NM_019106SEPT31
NM_173638NBPF151
NM_0011026631
NM_015383NBPF141
NM_183372NBPF111
XM_001128986LOC7289801
NM_032264NBPF31
NM_144671FAM109A1
NM_005229ELK11
NM_002901RCN11
NM_080591PTGS11
NM_000962PTGS11
NM_001939DRP21
NM_017861PIGX1
NM_014765TOMM201
NM_017740ZDHHC71
NM_001400EDG11
NM_004921CLCA31
NM_057178RFFL1
NM_001017368RFFL1
NM_014381MLH31
NM_001040108MLH31
NM_139076CCDC981
XM_934514LOC6447141
XM_945782LOC6447141
NM_005202COL8A21
NM_000240MAOA1
NM_012443SPAG61
NM_172242SPAG61
NM_006749SLC20A21
NM_030806C1orf211
NM_025152NUBPL1
NM_001001581PDE9A1
NM_001001582PDE9A1
NM_001001573PDE9A1
NM_001001580PDE9A1
NM_002606PDE9A1
NM_001001576PDE9A1
NM_001001574PDE9A1
NM_001001569PDE9A1
NM_001001578PDE9A1
NM_001001577PDE9A1
NM_001001568PDE9A1
NM_001001572PDE9A1
NM_001001579PDE9A1
NM_001001571PDE9A1
NM_001001567PDE9A1
NM_001001585PDE9A1
NM_001001575PDE9A1
NM_001001584PDE9A1
NM_001001583PDE9A1
NM_001001570PDE9A1
NM_0010986381
NM_198515C10orf961
XM_001129914LOC7293121
XM_001129492LOC7313991
NM_147173NUDT21
NM_147172NUDT21
NM_001161NUDT21
NM_007175ERLIN21
XM_001130949LOC1583761
XM_001129749LOC1583761
NM_014757MAML11
XM_001126853MAML11
NM_007047BTN3A21
NM_016407C20orf431
NM_177996EPB41L11
NM_012156EPB41L11
NM_015530GORASP21
NM_0529271
NM_007203PALM2-AKAP21
NM_147150PALM2-AKAP21
NM_001004065AKAP21
NM_001040152PEG101
NM_015068PEG101
NM_201520SLC25A351
NM_198484ZNF6211
NM_0010984141
NM_001385DPYS1
NM_181706DPH41
NM_001077196PDE11A1
NM_001077197PDE11A1
NM_016953PDE11A1
NM_001031749LYPD51
NM_182573LYPD51
NM_001001712LCN101
NM_006890CEACAM71
NM_004090DUSP31
NM_016614TTRAP1
NM_014817KIAA06441
NM_017945SLC35A51
NM_006823PKIA1
NM_181839PKIA1
NM_005312RAPGEF11
NM_198679RAPGEF11
NM_014782ARMCX21
NM_177949ARMCX21
NM_001001524TM6SF21
NM_203382AMACR1
NM_020772NUFIP21
XM_001125832LOC7277641
NM_001033515LOC3898331
XM_001127121LOC7282981
NM_003298NR2C21
NM_003768PEA151
NM_004051BDH11
NM_203315BDH11
NM_203314BDH11
NM_014308PIK3R51
NM_013955NOX11
NM_007052NOX11
NM_138444KCTD121
NM_020208SLC6A201
NM_022405SLC6A201
NM_001012511GOSR21
NM_145739OSBPL61
NM_032523OSBPL61
NM_024948C10orf971
NM_032782HAVCR21
NM_001039029LRTM21
NM_152263TPM31
NM_001025202LOC4425821
NM_001013739LOC4425781
NM_001039132ICAM41
NM_001544ICAM41
NM_001082534CA101
NM_020178CA101
NM_001082533CA101
NM_003507FZD71
NM_206853QKI1
NM_206854QKI1
NM_206855QKI1
NM_006546IGF2BP11
XM_001130020KIAA11471
XM_001130081KIAA11471
NM_001080392KIAA11471
NM_0011112831
NM_000618IGF11
NM_0011112841
NM_002230JUP1
XM_001132018FLJ401251
NM_001080401FLJ401251
XM_001128282LOC7281381
NM_138346KIAA20131
NM_015267CUTL21
NM_016138COQ71
NM_003748ALDH4A11
NM_007007CPSF61
NM_016544RBJ1
NM_024408NOTCH21
XM_001133349NOTCH21
XM_001132247C1orf1081
NM_001609ACADSB1
NM_024081PRRG41
NM_006650CPLX21
NM_001008220CPLX21
NM_014431KIAA12741
NM_003898SYNJ21
NM_015670SENP31
NM_018342TMEM1441
NM_198529EFCAB51
NM_033020TRIM331
NM_015906TRIM331
NM_002119HLA-DOA1
NM_016073HDGFRP31
NM_012244SLC7A81
NM_182728SLC7A81
NM_133496SLC30A71
NM_0011096621
NM_002608PDGFB1
NM_033016PDGFB1
NM_015326SRGAP21
NM_139164STARD41
NM_001003652SMAD21
NM_005901SMAD21
NM_014819PJA21
NM_001031853INSC1
NM_001042536INSC1
NM_015465GEMIN51
NM_025218ULBP11
XM_001128449LOC7281971
NM_080725SRXN11
NM_016932SIX21
NM_005065SEL1L1
NM_003198TCEB31
NM_019899ABCC11
NM_019862ABCC11
NM_019898ABCC11
NM_004996ABCC11
NM_019900ABCC11
NM_0152831
NM_003681PDXK1
NM_016090RBM71
NM_198968DZIP11
NM_014934DZIP11
NM_014945ABLIM31
NM_080282ABCA101
NM_001406EFNB31
NM_178505TMEM261
NM_001080485ZNF2751
NM_003784SERPINB71
NM_001040147SERPINB71
NM_032246RKHD31
NM_020665TMEM271
NM_001025266LOC2853821
NM_001018115FANCD21
NM_017693BIVM1

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317