Predicted Off-targets for siRNA "guccuaacuauaugcggca" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

1 hit was found for GUCCUAACUAUAUGCGGCA (1 guide strand hits and 0 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_152503 C20orf132 2796 2814 GUCCUAACUAUAUGuGcCc46 3 14 c false   <90%   3437



3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1145
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_030641APOL64
NM_017759FLJ203093
NM_015879ST8SIA33
NM_006045ATP9A3
XM_944029LOC6479793
NM_145259ACVR1C2
NM_0011110312
NM_0011110332
NM_0011110322
NM_052932TMEM1232
NM_032303HSDL22
NM_000084CLCN52
NM_016206VGLL32
NM_005715UST2
NM_006206PDGFRA2
NM_002336LRP62
NM_004262TMPRSS11D2
NM_006572GNA132
NM_001025300RAB122
NM_001018065NTRK22
NM_001018066NTRK22
NM_015185ARHGEF92
NM_006581FUT92
NM_002829PTPN32
NM_152376UBXD32
NM_194247HNRPA32
NM_018214LRRC12
NM_144664FAM76B2
NM_006469IVNS1ABP2
NM_015367BCL2L132
NM_002725PRELP2
NM_201348PRELP2
NM_016352CPA42
NM_0010996272
NM_006933SLC5A32
NM_133482RAD502
NM_005732RAD502
NM_018452C6orf352
NM_001077243GRIA42
NM_000829GRIA42
NM_153442GPR262
NM_005402RALA2
NM_020717SHROOM42
NM_145256LRRC252
NM_005840SPRY32
NM_0011097542
NM_002837PTPRB2
NM_032228MLSTD22
NM_015329KIAA08922
NM_024164TPSB22
NM_003294TPSAB12
NM_005898CAPRIN12
NM_003681PDXK2
NM_183376ARRDC42
NM_030648SETD72
NM_002657PLAGL22
XM_941807NHSL12
XM_496826NHSL12
NM_173833SCARA52
NM_001010846SHE2
NM_017681NUP62CL1
NM_019887DIABLO1
NM_138929DIABLO1
NM_138930DIABLO1
NM_015018DOPEY11
NM_018644B3GAT11
NM_054025B3GAT11
NM_000461THRB1
NM_003216TEF1
NM_024590ARSJ1
NM_207469DEFB321
NM_024674LIN281
NM_002451MTAP1
NM_0207331
NM_002703PPAT1
NM_025203C2orf441
NM_004538NAP1L31
NM_004789LHX21
NM_000629IFNAR11
NM_006148LASP11
NM_014232VAMP21
NM_012154EIF2C21
NM_004586RPS6KA31
NM_005204MAP3K81
NM_007249KLF121
XM_001133842LOC7294461
NM_001010923C6orf1901
NM_020144PAPOLB1
NM_002508NID11
NM_014335EID11
NM_005611RBL21
NM_0207001
NM_014711CP1101
NM_058179PSAT11
NM_021154PSAT11
NM_207391RGS9BP1
NM_203364CAPRIN11
NM_001743CALM21
XM_933931LOC6467741
NM_0011052071
NM_002290LAMA41
NM_0011052061
NM_001010891MTX31
NM_130759GIMAP11
XM_373600LOC3880021
XM_944015LOC3880021
NM_002634PHB1
NM_003787NOL41
NM_001001331ATP2B21
NM_001683ATP2B21
NM_152450FAM81A1
NM_003274TMEM11
XM_933646LOC6464841
XM_943429LOC6464841
NM_005962MXI11
NM_001008541MXI11
NM_130439MXI11
NM_002158FOXN21
NM_0011023961
NM_025073SIKE1
NM_001039840CHIC11
NM_003898SYNJ21
NM_022497MRPS251
NM_133477SYNPO21
XM_942776SYNPO21
XM_936336SYNPO21
XM_293918LOC3456431
XM_938591LOC3456431
NM_004434EML11
NM_001008707EML11
NM_0011006211
NM_017941C17orf801
NM_033429CALML41
NM_001031733CALML41
NM_153364FAM71C1
NM_015411SUMF21
NM_001042470SUMF21
NM_001042468SUMF21
NM_001042469SUMF21
NM_003027SH3GL31
NM_018177N4BP21
NM_014893NLGN4Y1
NM_001032731OAS21
NM_030758OSBP21
NM_024843CYBRD11
NM_018157RIC8B1
NM_022459XPO41
NM_000189HK21
NM_019021C11orf711
NM_001008539SLC7A21
NM_003046SLC7A21
NM_001001874TPD52L31
NM_014826CDC42BPA1
NM_003607CDC42BPA1
NM_001040214TCBA11
NM_000733CD3E1
NM_024906SCD51
NM_015090NFASC1
XM_001134379LOC7323501
XM_001128421LOC7280691
NM_014646LPIN21
NM_021110COL14A11
NM_006773DDX181
XM_945519LOC6524491
NM_001040441ZBTB81
XM_001124597LOC7304111
NM_001004125TUSC11
NM_020346SLC17A61
NM_005335HCLS11
NM_001015508PURG1
NM_005105RBM8A1
NM_018385LSG11
NM_053023ZFP911
NM_001042404CEP1701
NM_014812CEP1701
NM_001042405CEP1701
NM_016523KLRF11
NM_016097IER3IP11
NM_012305AP2A21
NM_024313NOL121
NM_145280FAM119A1
NM_004293GDA1
XM_001126254LOC7305381
XM_001131842LOC7303581
XM_001131526LOC7298521
NM_001414EIF2B11
NM_016021UBE2J11
NM_018263ASXL21
NM_025146NAT131
XM_001127597FLJ328101
XM_001127587FLJ328101
XM_925815FLJ328101
XM_001127637FLJ328101
XM_001127623FLJ328101
NM_003752EIF3S81
NM_001037808EIF3S81
XM_001132506LOC7286891
XM_001132509LOC7286891
XM_001132505LOC7286891
NM_0010996611
NM_032932RAB11FIP41
NM_175080P2RX51
NM_002561P2RX51
NM_001001668ZNF4701
NM_014298QPRT1
NM_007326CYB5R31
NM_000398CYB5R31
NM_024910ZNF7671
NM_007250KLF81
NM_013281FLRT31
NM_198391FLRT31
NM_002334LRP41
XM_938665USP6NL1
NM_001080491USP6NL1
XM_927409USP6NL1
XM_943800USP6NL1
NM_001128AP1G11
NM_001030007AP1G11
NM_024701ASB131
NM_001083625ANKRD121
NM_015208ANKRD121
NM_000112SLC26A21
NM_018303EXOC21
NM_019891ERO1LB1
NM_174921C4orf341
NM_138444KCTD121
NM_002449MSX21
NM_033544RCCD11
NM_001017919RCCD11
NM_152622MIER31
NM_022474MPP51
NM_003057SLC22A11
NM_153187SLC22A11
NM_0330261
NM_0010394961
NM_198896RAB6A1
NM_002869RAB6A1
NM_001077637LOC1507861
NM_032144RAB6C1
NM_007363NONO1
NM_020315PDXP1
NM_033100PCDH211
NM_001040273TYSND11
NM_173555TYSND11
NM_138731MIPOL11
NM_001039523CHRNA11
NM_000079CHRNA11
NM_133264WIPF21
NM_000800FGF11
NM_033137FGF11
NM_033136FGF11
NM_000390CHM1
NM_052918SORCS11
NM_001013031SORCS11
NM_1449931
NM_000183HADHB1
NM_020890KIAA15241
NM_015375RIPK51
NM_199462RIPK51
NM_174911FAM84B1
NM_018279TMEM191
NM_0010839621
NM_003199TCF41
NM_032287LDOC1L1
NM_000554CRX1
XM_933539MGC30321
XM_944529MGC30321
NM_052909KIAA19091
NM_133444ZNF5261
NM_001497B4GALT11
NM_030936RNF321
NM_014661FAM53B1
NM_024948C10orf971
NM_080870DPCR11
NM_138423CASC41
NM_177974CASC41
NM_022767ISG20L11
NM_052876BTBD14B1
NM_003409ZFP1611
NM_145309LRRC511
NM_019009TOLLIP1
NM_001012418LOC3401561
NM_138715MSR11
NM_138716MSR11
NM_0010999521
NM_002222ITPR11
NM_005026PIK3CD1
NM_0011024211
NM_0011024201
NM_006007ZFAND51
NM_152550SH3RF21
NM_003506FZD61
NM_173853KRTCAP31
NM_032316NICN11
NM_0178921
NM_006408AGR21
NM_001004306MGC876311
XM_943193LOC4000271
XM_931434LOC4000271
NM_024989PGAP11
XM_001133211LOC7290031
XM_001133556LOC7291351
NM_001496GFRA31
NM_021815SLC5A71
NM_001388DRG21
NM_152735ZBTB91
NM_018048FLJ102921
NM_001079526IKZF21
NM_016260IKZF21
NM_031844HNRPU1
NM_004501HNRPU1
NM_001969EIF51
NM_183004EIF51
NM_080632UPF3B1
NM_023010UPF3B1
NM_199452ZNF3651
NM_199451ZNF3651
NM_000351STS1
NM_024761MOBKL2B1
NM_173649FLJ401721
NM_015455CNOT61
NM_153450MED191
NM_006811SERINC31
NM_005188CBL1
NM_001659ARF31
NM_000436OXCT11
NM_001002026CLDN181
NM_016369CLDN181
NM_005160ADRBK21
NM_002445MSR11
XM_944246LOC6486951
XM_931860LOC6429541
NM_006837COPS51
NM_004665VNN21
NM_078488VNN21
NM_138445GPR1461
NM_203488ACYP11
NM_201624USP331
NM_015017USP331
NM_020751COG61
NM_018085IPO91
NM_183356ASNS1
NM_133436ASNS1
NM_004852ONECUT21
NM_207418FAM72A1
XM_001133364LOC7295331
XM_001133363LOC7295331
XM_001133365LOC7295331
NM_0011009101
NM_016128COPG1
NM_199421SOCS41
NM_080867SOCS41
NM_001673ASNS1
NM_0010996661
NM_0010996261
NM_019557FAM54B1
NM_0010996251
NM_0011008291
NM_176823S100A7A1
NM_004999MYO61
NM_000754COMT1
NM_007310COMT1
NM_152289ZNF5611
NM_017656ZNF5621
NM_173602DIP2B1
NM_182916TRNT11
NM_020718USP311
NM_020200PRTFDC11
NM_020341PAK71
NM_177990PAK71
NM_145011ZNF251
NM_144694ZNF5701
NM_182503DEADC11
XM_929433LOC6440061
XM_939111LOC6500201
NM_002938RNF41
NM_001751CARS1
NM_139273CARS1
NM_001014438CARS1
NM_001014437CARS1
NM_004106FCER1G1
NM_018078LARP21
NM_144607CYB5D11
NM_015713RRM2B1
NM_178498SLC5A121
NM_005100AKAP121
NM_144497AKAP121
XM_939100MYO5B1
NM_001080467MYO5B1
NM_015313ARHGEF121
NM_018658KCNJ161
NM_170742KCNJ161
NM_170741KCNJ161
NM_014141CNTNAP21
NM_012413QPCT1
NM_000926PGR1
NM_032457PCDH71
NM_203403C9orf1501
NM_194292SASS61
NM_203437AFTPH1
NM_001002243AFTPH1
NM_017657AFTPH1
NM_018121C10orf61
NM_001009909LUZP21
NM_0209111
NM_014830ZBTB391
NM_033055HIAT11
NM_152636METT5D11
NM_033210ZNF5021
NM_198847FAM111A1
NM_022074FAM111A1
NM_032153ZIC41
NM_198381ELF51
NM_001422ELF51
NM_004254SLC22A81
NM_001008408RBM331
NM_053043PRR81
NM_133443GPT21
NM_007259VPS451
NM_001125ADPRH1
NM_181523PIK3R11
NM_181504PIK3R11
NM_181524PIK3R11
NM_198353KCTD81
NM_021813BACH21
NM_001012339DNAJA51
NM_194283DNAJA51
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_152680TMEM1541
NM_016298FBXO401
NM_006287TFPI1
NM_014285EXOSC21
NM_007054KIF3A1
NM_004612TGFBR11
NM_032446MEGF101
NM_173464L3MBTL41
NM_017641KIF21A1
XM_937200RPTN1
XM_371312RPTN1
NM_212471PRKAR1A1
NM_212472PRKAR1A1
NM_002734PRKAR1A1
NM_182499TDRD101
NM_0010984751
NM_005941MMP161
NM_147180PPP3R21
NM_004058CAPS1
NM_080590CAPS1
NM_014924KIAA08311
NM_003706PLA2G4C1
NM_133639RHOV1
NM_030819GFOD21
NM_004393DAG11
NM_015015JMJD2B1
NM_016106SCFD11
NM_182835SCFD11
NM_001039569AP1S31
NM_052880PIK3IP11
NM_014106ZNF7701
NM_0245241
NM_017861PIGX1
NM_006618JARID1B1
NM_015221DNMBP1
NM_006624ZMYND111
NM_015271TRIM21
NM_022346NCAPG1
NM_001621AHR1
NM_144570HN1L1
NM_213654ARMC81
NM_014154ARMC81
NM_000651CR11
NM_000573CR11
NM_006918SC5DL1
NM_001024956SC5DL1
NM_004707ATG121
NM_001241CCNT21
NM_058241CCNT21
NM_002745MAPK11
NM_152731C6orf651
NM_000839GRM21
NM_020393PGLYRP41
NM_001030055ARHGAP51
NM_001173ARHGAP51
NM_020177FEM1C1
NM_004687MTMR41
NM_001045556SLA1
NM_006748SLA1
NM_001045557SLA1
NM_152362TNFAIP8L11
NM_001042574CRTC31
NM_022769CRTC31
NM_003768PEA151
NM_006539CACNG31
NM_012218ILF31
NM_004308ARHGAP11
NM_004745DLGAP21
NM_005831CALCOCO21
XM_001127102LOC6478591
XM_001130815LOC6478591
NM_002405MFNG1
NM_201628FLJ438061
NM_001669ARSD1
NM_198581ZC3H61
NM_173598KSR21
NM_004339PTTG1IP1
NM_000210ITGA61
NM_001079818ITGA61
NM_152623CDC20B1
NM_0155621
NM_016154RAB4B1
NM_001001706FLJ421771
NM_000727CACNG11
NM_0011127361
NM_015224C3orf631
NM_006861RAB351
XM_001131577FLJ366441
XM_001126095FLJ366441
NM_004042ARSF1
NM_000912OPRK11
XM_001126926LOC7279341
XM_001133457LOC7317721
NM_152588TMTC21
NM_017952PTCD31
XM_001134344FLJ374531
XM_001133818LOC7296141
NM_012443SPAG61
NM_172242SPAG61
NM_004101F2RL21
NM_000624SERPINA51
NM_015247CYLD1
NM_001042412CYLD1
NM_001042355CYLD1
NM_145321OSBPL31
NM_145320OSBPL31
NM_145322OSBPL31
NM_015550OSBPL31
NM_013381TRHDE1
NM_145802SEPT61
NM_145800SEPT61
NM_016823CRK1
NM_005206CRK1
NM_024993LRRTM41
NM_001010984C1orf1241
NM_014803ZNF5181
NM_004438EPHA41
NM_030621DICER11
NM_177438DICER11
NM_003060SLC22A51
NM_001008537KIAA20221
NM_001006641SLC25A251
NM_001006642SLC25A251
NM_052901SLC25A251
NM_001006643SLC25A251
NM_020802KIAA13771
NM_001830CLCN41
NM_152355ZNF4411
NM_005027PIK3R21
NM_058238WNT7B1
NM_025182KIAA15391
NM_001013620ALG10B1
NM_015855WIT11
NM_016023OTUD6B1
NM_0148311
NM_003212TDGF11
NM_014051TMEM14A1
NM_012464TLL11
NM_0209101
NM_018141MRPS101
NM_018265C1orf1061
NM_018979WNK11
NM_002646PIK3C2B1
NM_173355UPP21
NM_032788ZNF5141
NM_001018075NR3C11
NM_001018077NR3C11
NM_001018076NR3C11
NM_001018074NR3C11
NM_001024094NR3C11
NM_000176NR3C11
NM_0314131
NM_005434MALL1
NM_022337RAB381
NM_0010988141
NM_170665ATP2A21
NM_203349SHC41
NM_002030FPRL21
NM_004514FOXK21
XM_001134363FOXK21
XM_001134364FOXK21
NM_004385VCAN1
NM_014945ABLIM31
NM_015533DAK1
NM_032783CBR41
NM_017846TRSPAP11
NM_017637BNC21
NM_173645FLJ373571
XM_001134463BAHCC11
NM_001080519BAHCC11
NM_004290RNF141
NM_183400RNF141
NM_183398RNF141
NM_183401RNF141
NM_183399RNF141
NM_033090GREB11
NM_018364RSBN11
NM_014943ZHX21
NM_020753CASKIN21
NM_019894TMPRSS41
NM_0010839471
NM_022496ACTR61
NM_133330WHSC11
NM_001042424WHSC11
NM_133331WHSC11
NM_133335WHSC11
NM_018351FGD61
NM_016173HEMK11
NM_016938EFEMP21
NM_014000VCL1
NM_003373VCL1
NM_005238ETS11
NM_022757CCDC141
NM_016258YTHDF21
NM_003489NRIP11
NM_170774RASSF21
NM_014737RASSF21
NM_024095ASB81
NM_000322PRPH21
NM_012323MAFF1
NM_152878MAFF1
NM_003030SHOX21
NM_006884SHOX21
NM_0010987211
NM_0010987221
NM_004485GNG41
NM_145865ANKS4B1
XM_001130189LOC7315981
XM_001129850LOC7292911
NM_001079911DMP11
NM_004407DMP11
NM_016297PCYOX11
XM_001126978LOC7307311
NM_001381DOK11
NM_183394CADPS1
NM_003716CADPS1
NM_183393CADPS1
NM_022041GAN1
NM_020349ANKRD21
NM_014292CBX61
XM_001131480ALOX151
NM_024345WDR321
NM_013446MKRN11
NM_020731AHRR1
XM_925959LOC6424461
XM_936370LOC6422191
XM_061890TRIM641
NM_031949TTLL21
NM_001991EZH11
NM_006080SEMA3A1
NM_014246CELSR11
NM_152624DCP21
NM_004741NOLC11
NM_016544RBJ1
NM_018700TRIM361
NM_198148CPXM21
NM_016396CTDSPL21
NM_003129SQLE1
XM_001129595LOC7291841
XM_001128760LOC7311861
NM_198399ARPP-211
NM_001025069ARPP-211
NM_001025068ARPP-211
NM_001259CDK61
NM_005900SMAD11
NM_001003688SMAD11
NM_153620HOXA11
NM_005522HOXA11
NM_138774C19orf221
NM_017791C14orf581
NM_152310ELOVL31
NM_174934SCN4B1
NM_024577SH3TC21
NM_022152TMBIM11
NM_031892SH3KBP11
NM_012223MYO1B1
NM_012400PLA2G2D1
NM_153456HS6ST31
NM_002463MX21
NM_018346RSAD11
NM_001004303C1orf1681
NM_144590ANKRD221
NM_014494TNRC6A1
NM_014877HELZ1
NM_017982SUSD41
NM_003426ZNF741
NM_001002800SMC41
NM_005496SMC41
NM_000185SERPIND11
NM_134424RAD521
NM_001005337PKP11
NM_000299PKP11
NM_198951TGM21
NM_004711SYNGR11
NM_024693ECHDC31
NM_014239EIF2B21
NM_0011008731
NM_017972C14orf1181
NM_017926C14orf1181
NM_001008390CGGBP11
NM_003663CGGBP11
NM_019903ADD31
NM_016824ADD31
NM_001121ADD31
NM_031490LONP21
XM_001129857PDDC11
NM_182612PDDC11
NM_015101GLT25D21
NM_018243SEPT111
NM_003724JRK1
NM_014309RBM91
NM_001082576RBM91
NM_001082577RBM91
NM_001031695RBM91
NM_001082578RBM91
NM_001082579RBM91
NM_005910MAPT1
NM_016841MAPT1
NM_016834MAPT1
NM_016835MAPT1
NM_015259ICOSLG1
NM_017415KLHL31
NM_002534OAS11
NM_033141MAP3K91
NM_013230CD241
NM_001217CA111
NM_032189ATP11A1
NM_015205ATP11A1
NM_002416CXCL91
NM_207006FAM83A1
NM_181714C6orf1521
NM_013411AK21
NM_005779LHFPL21
XM_001134350LOC7301811
XM_001133934LOC7318241
NM_144968RIBC11
NM_000870HTR41
NM_001040172HTR41
NM_001040173HTR41
NM_006763BTG21
NM_001970EIF5A1
NM_031275TEX121
NM_014631SH3PXD2A1
NM_014798PLEKHM11
XM_001128220PLEKHM11
NM_144684ZNF4801
NM_020853KIAA14671
NM_015299KIAA03231
NM_198484ZNF6211
NM_0010984141
NM_002079GOT11
NM_001852COL9A21
NM_004448ERBB21
NM_001005862ERBB21
NM_025074FRAS11
NM_177948ARMCX31
NM_177947ARMCX31
NM_016607ARMCX31
NM_006516SLC2A11
NM_198057TSC22D31
NM_001015881TSC22D31
NM_004089TSC22D31
NM_004079CTSS1
NM_015959TXNDC141
NM_032452JPH41
NM_005883APC21
NM_182898CREB51
NM_004904CREB51
NM_001011666CREB51
NM_182899CREB51
XM_928464LOC1465171
NM_178427ARNT1
NM_178426ARNT1
NM_001668ARNT1
NM_030806C1orf211
NM_001065TNFRSF1A1
NM_001039547GK51
NM_013402FADS11
NM_016076C1orf1211
NM_002023FMOD1
NM_007021C10orf101
NM_002204ITGA31
NM_005501ITGA31
NM_002644PIGR1
NM_153810C10orf461
NM_002119HLA-DOA1
NM_020128MDM11
NM_001955EDN11
NM_153823GSG11
NM_031289GSG11
NM_001080555GSG11
NM_001080554GSG11
NM_0010986381
NM_005915MCM61
NM_134431SLCO1A21
XM_941142FTO1
NM_001080432FTO1
NM_016513ICK1
NM_014920ICK1
XM_001130700LOC7295801
XM_001126751LOC7306721
NM_022898BCL11B1
NM_138576BCL11B1
NM_004572PKP21
NM_001005242PKP21
NM_003708RDH161
NM_144775SMCR81
XM_373030LOC2855561
XM_939505LOC2855561
NM_003193TBCE1
NM_001079515TBCE1
NM_014911AAK11
NM_0010985271
NM_006605RFPL21
NM_021026RFPL11
NM_004863SPTLC21
NM_198841FAM120AOS1
NM_003929RAB7L11
XM_001126406LOC7279221
NM_025224ZBTB461
NM_033133CNP1
NM_002638PI31
NM_019855CABP51
NM_001467SLC37A41
NM_032266C2orf161
NM_130785TPTE21
NM_199254TPTE21
NM_004663RAB11A1
NM_0151771
NM_015257KIAA02861
NM_018717MAML31
NM_032373PCGF51
NM_145176SLC2A121
NM_020918GPAM1
NM_000104CYP1B11
NM_001690ATP6V1A1
NM_000723CACNB11
NM_194329RNF381
NM_194328RNF381
NM_194330RNF381
NM_022781RNF381
NM_194332RNF381
NM_017665ZCCHC101
NM_018951HOXA101
NM_153715HOXA101
NM_002903RCVRN1
NM_005199CHRNG1
NM_004842AKAP71
NM_138633AKAP71
NM_016377AKAP71
NM_032236USP481
NM_001076682NCAM11
NM_019072SGTB1
NM_006734HIVEP21
NM_015368PANX11
NM_198468C6orf1671
NM_080868ASB171
NM_014061MAGEH11
NM_001512GSTA41
NM_014007ZBTB431
XM_932212LOC6444891
XM_945584LOC6524981
NM_144717IL20RB1
NM_022557GH21
NM_000515GH11
NM_022560GH11
NM_022562GH11
NM_022561GH11
NM_022559GH11
NM_022556GH21
NM_002059GH21
NM_022641CSH11
NM_020991CSH21
NM_001317CSH11
NM_022645CSH21
NM_022640CSH11
NM_022644CSH21
NM_014349APOL31
NM_145642APOL31
NM_145640APOL31
NM_145639APOL31
NM_030644APOL31
NM_145641APOL31
NM_030643APOL41
NM_145660APOL41
NM_015251ASCIZ1
NM_198887NUP431
NM_020337ANKRD501
NM_018518MCM101
NM_182751MCM101
NM_032818C9orf1001
NM_198990NAPE-PLD1
NM_006691XLKD11
NM_198124CSMD31
NM_198123CSMD31
NM_052900CSMD31
NM_003692TMEFF11
NM_003082SNAPC11
NM_139175RNF1331
NM_024832RIN31
XM_001133280FLJ410471
XM_001132703FLJ410471
NM_014331SLC7A111
NM_031911C1QTNF71
NM_032869NUDCD11
NM_015235CSTF2T1
NM_001044387ZNF5571
NM_024341ZNF5571
NM_001044388ZNF5571
NM_018227UBE1L21
NM_004985KRAS1
NM_033360KRAS1
NM_005113GOLGA51
NM_016250NDRG21
NM_201538NDRG21
NM_201537NDRG21
NM_201536NDRG21
NM_201535NDRG21
NM_201540NDRG21
NM_201539NDRG21
NM_201541NDRG21
NM_015975TAF9B1
XM_001126120LOC7281981
NM_015264C22orf91
NM_001009880C22orf91
NM_138636TLR81
NM_020714ZNF4901
NM_002039GAB11
NM_207123GAB11
NM_172344KCNG31
NM_133329KCNG31
NM_0011016761
NM_001395DUSP91
NM_147175HS6ST21
NM_001077188HS6ST21
XM_943028LOC6477951
NM_020443NAV11
NM_005399PRKAB21
NM_004598SPOCK11
NM_021156TXNDC131
NM_000198HSD3B21
NM_000862HSD3B11
NM_153263ZNF5491
NM_201526ISLR1
NM_005545ISLR1
NM_001025356TMEM16F1
XM_929878LOC6469151
NM_138797ANKRD541
NM_023074ZNF6491
NM_152388ALS2CR41
NM_001044385ALS2CR41
XM_001125986LOC2838241
NM_022166XYLT11
NM_139018CD300LF1
NM_014233UBTF1
NM_001076683UBTF1
NM_001076684UBTF1
NM_019600KIAA13701
NM_032449CC2D1B1
NM_183078RNF81
NM_003958RNF81
NM_002977SCN9A1
NM_005446P2RXL11
NM_194285SPTY2D11
XM_934166LOC6534411
NM_004426PHC11
NM_152722HEPACAM1
NM_024627C22orf291
NM_021643TRIB21
NM_030613ZFP21
NM_003157NEK41
NM_024295DERL11
NM_004654USP9Y1
NM_017848FAM120C1
NM_001482GATM1
NM_003588CUL4B1
NM_001079872CUL4B1
NM_198846SIGLEC61
NM_198845SIGLEC61
NM_001245SIGLEC61
NM_000831GRIK31
NM_007107SSR31
NM_014756CKAP51
NM_001008938CKAP51
NM_003836DLK11
NM_015954DERA1
NM_032359C3orf261
NM_001018008TPM11
NM_020766PCDH191
NM_0011052431
NM_001077440BCLAF11
NM_001077441BCLAF11
NM_014739BCLAF11
NM_030755TXNDC11
XM_001127232LOC7279711
NM_021961TEAD11
NM_014347ZNF3241
XM_001126216LOC7279481
NM_001012417MS4A131
NM_0011009091
NM_001031692LRRC171
NM_005824LRRC171
NM_012447STAG31
NM_017915C12orf481
NM_020321ACCN31
NM_004769ACCN31
NM_006089SCML21
NM_000313PROS11
NM_194284CLDN231
NM_152271LONRF11
NM_194314ZBTB411
NM_003439ZKSCAN11
NM_014862ARNT21
NM_006815TMED21
XM_001127710LOC7286531
NM_005158ABL21
NM_007314ABL21
NM_0011001081
XM_944835LOC6486911
NM_003217TEGT1
NM_0010985761
NM_030766BCL2L141
NM_015540RPAP11
NM_007011ABHD21
NM_152924ABHD21
NM_000214JAG11
NM_198968DZIP11
NM_014934DZIP11
NM_0010099841
NM_002063GLRA21
NM_012164FBXW21
NM_003762VAMP41
NM_138619GGA31
NM_014001GGA31
NM_017628KIAA15461
NM_006696BRD81
NM_183359BRD81
NM_145044ZNF5011
NM_006036PREPL1
NM_001042386PREPL1
NM_001042385PREPL1
NM_001002912C1orf1731
NM_005819STX61
NM_018400SCN3B1
NM_001040151SCN3B1
NM_006769LMO41
NM_018057SLC6A151
NM_003659AGPS1
NM_000314PTEN1
NM_0195891
NM_004857AKAP51
NM_012198GCA1
NM_012153EHF1
NM_130799MEN11
NM_130801MEN11
NM_000244MEN11
NM_130803MEN11
NM_130800MEN11
NM_130804MEN11
NM_130802MEN11
NM_012288TRAM21
NM_198941SERINC31
NM_001040647RCP91
NM_001040648RCP91
NM_014478RCP91
NM_001682ATP2B11
NM_001001323ATP2B11
NM_005562LAMC21
XM_001131019LOC7318461
XM_001131201LOC7297511
NM_178826TMEM16D1
NM_002731PRKACB1
NM_182948PRKACB1
NM_016577RAB6B1
NM_017596KIF21B1
NM_032182KIAA01571
NM_194434VAPA1
NM_003574VAPA1
NM_006635ZNF4601
NM_004938DAPK11
NM_145025C6orf1991
NM_145257C1orf961
NM_018429BDP11
NM_024884L2HGDH1
NM_007345ZNF2361
NM_006789APOBEC21
NM_002940ABCE11
NM_001040876ABCE11
NM_006559KHDRBS11
NM_147202C9orf251
NM_022461AZI21
XM_931945LOC6439621
XM_943665LOC6439621
NM_019618IL1F91
NM_018489ASH1L1
NM_001042751STAG21
NM_001042750STAG21
NM_001042749STAG21
NM_006603STAG21
NM_003478CUL51
NM_173496MPP71
NM_001543NDST11
NM_198074OR2C31
NM_001046SLC12A21
NM_0010853841
NM_181472CMTM71
NM_138410CMTM71
NM_018182C17orf631
NM_001077498C17orf631
NM_000686AGTR21
NM_000990RPL27A1
NM_020933ZNF3171
NM_001003652SMAD21
NM_005901SMAD21
NM_014240LIMD11
NM_001012659ARGFX1
NM_006654FRS21
NM_001042555FRS21
NM_006731FCMD1
NM_001079802FCMD1
NM_006683FAM12A1
NM_174940TMEM801
NM_001042463TMEM801
NM_173627FLJ352201
NM_152785GCET21
NM_001008756GCET21
NM_024969FAM130A21
NM_080723NRSN11
NM_138278BNIPL1
NM_006197PCM11
XM_001132109LOC7300201
NM_153254TTLL101
NM_0148561
NM_0010994141
NM_012206HAVCR11
NM_017413APLN1

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317