Predicted Off-targets for siRNA "ccuaugaagaccuaagagu" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

10 hits were found for CCUAUGAAGACCUAAGAGU (10 guide strand hits and 0 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_018330 KIAA1598 354 372 aaUAUGAAGACCUuAGAGc62 4 11 c false   <90%   3415
NM_004978 KCNC4 2200 2218 gCUuUGAAGACCUAAGAGg56 3 14 bc false   <90%   3713
NM_015158 ANKRD15 2392 2410 gCUgUGAAGACCaAAGAGU50 3 8   false   <90%   5083
NM_153186 ANKRD15 2572 2590 gCUgUGAAGACCaAAGAGU50 3 8   false   <90%   5263
NM_004774 PPARBP 4312 4330 uCUAaGAAGACCUcAGAGU27 3 8 c false   <90%   5809
XR_017390 LOC645339 600 618 CCUAUGAAGACCUAcccuU23 4 14 c false   <90%   769
XR_019228 LOC650068 600 618 CCUAUGAAGACCUAcccuU23 4 14 c false   <90%   769
NM_003430 ZNF91 1961 1979 CCUAaGAAGACaUAAGAGg9 3 6   false   <90%   5403
NM_181720 ARHGAP30 2181 2199 CCUAUGAuGACCUAAGucc6 4 8 c false   <90%   3888
NM_001025598 ARHGAP30 2181 2199 CCUAUGAuGACCUAAGucc6 4 8 c false   <90%   4425



3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1193
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_001012753ZNF7637
NM_1523576
NM_152605ZNF7816
NM_001017440CALN13
NM_031468CALN13
NM_003617RGS53
NM_033505SELI3
NM_015251ASCIZ3
NM_152262ZNF4393
NM_024577SH3TC23
NM_173598KSR23
NM_015272KIAA10052
NM_0010996522
NM_054030MRGPRX22
NM_020297ABCC92
NM_138459NUS12
XM_001129792LOC7291482
NM_183075CYP2U12
NM_020917ZFP142
NM_020782KLHDC52
NM_003034ST8SIA12
NM_148957TNFRSF192
NM_001026213CYP11B12
NM_000497CYP11B12
NM_016239MYO15A2
NM_021202TP53INP22
NM_198480ZNF6152
NM_006197PCM12
NM_024798SNX222
NM_203371LOC3877582
NM_005140CNGA22
NM_003861WDR222
NM_018290PGM22
XM_001130526LOC7286362
XM_001130555LOC7286362
XM_001130543LOC7286362
XM_001130536LOC7286362
XM_925864LOC6423252
XM_001129399LOC6423462
XM_928707LOC6423462
XM_925879LOC6423462
NM_153620HOXA12
NM_005522HOXA12
NM_144973MGC240392
NM_016040TMED52
NM_001033087C20orf1332
NM_080676C20orf1332
NM_152455ZSCAN292
NM_176081TRDMT12
NM_004412TRDMT12
NM_176083TRDMT12
NM_0325302
NM_004079CTSS2
NM_144566ZNF7002
NM_025146NAT132
NM_023068SIGLEC12
NM_201263WARS22
NM_007249KLF122
NM_180991SLCO4C12
NM_012479YWHAG2
NM_004438EPHA42
NM_0011004172
NM_175748C14orf1302
NM_017637BNC22
NM_152253CHKB2
NM_152866MS4A12
NM_021950MS4A12
NM_006775QKI2
NM_004080DGKB2
NM_005504BCAT12
NM_020935USP372
NM_000809GABRA42
NM_001025079CD472
NM_001777CD472
NM_198793CD472
NM_004843IL27RA2
NM_138717PPT22
NM_005155PPT22
NM_207406CCDC42
NM_004852ONECUT22
NM_014911AAK12
NM_003412ZIC12
NM_007361NID21
NM_058172ANTXR21
NM_005665EVI51
NM_001033910TRAF51
NM_145759TRAF51
NM_004619TRAF51
NM_0010937791
NM_030583MATN21
NM_002380MATN21
NM_006633IQGAP21
NM_000411HLCS1
NM_014773KIAA01411
NM_020473PIGA1
NM_002641PIGA1
NM_001076682NCAM11
NM_016626RKHD21
NM_001040875GDAP11
NM_018972GDAP11
NM_0010853771
NM_002387MCC1
NM_001042404CEP1701
NM_014812CEP1701
NM_001042405CEP1701
NM_004590CCL161
NM_017993ENOX11
NM_173672PPIL61
NM_0011112981
NM_002210ITGAV1
NM_022828YTHDC21
NM_000074CD40LG1
NM_181776SLC36A21
NM_002745MAPK11
NM_024611NARG21
NM_001018089NARG21
NM_014443IL17B1
XM_929714LOC6467621
XM_938418LOC6467621
XM_935722LOC6467621
NM_013256ZNF1801
NM_023929ZBTB101
NM_0011055391
NM_015317PUM21
NM_152414BHLHB51
NM_213654ARMC81
NM_014154ARMC81
NM_001802CDR21
XM_930931ZDHHC11B1
XM_928660LOC6536531
XM_939725LOC6541271
NM_015338ASXL11
NM_133367PAQR81
NM_018353C14orf1061
NM_001029863C6orf1201
NM_0333901
NM_080760DACH11
NM_080759DACH11
NM_004392DACH11
NM_144657CXorf431
NM_199421SOCS41
NM_080867SOCS41
XM_001128716STX51
NM_003164STX51
NM_006359SLC9A61
NM_001042537SLC9A61
NM_005931MICB1
NM_000247MICA1
NM_032044REG41
NM_004295TRAF41
NM_0207331
NM_020657ZNF3041
XM_940438LOC6541741
NM_001040455SIDT21
NM_173822FAM126B1
NM_000912OPRK11
NM_017964SLC30A61
NM_002711PPP1R3A1
XM_378914KIAA04921
XM_944290KIAA04921
NM_198216SNRPB1
NM_003091SNRPB1
NM_033437PDE5A1
NM_001083PDE5A1
NM_033430PDE5A1
NM_152367C1orf1611
NM_014388C1orf1071
NM_004844SH3BP51
NM_001018009SH3BP51
NM_001083625ANKRD121
NM_015208ANKRD121
NM_003093SNRPC1
NM_030966KRTAP1-31
XM_001128885LOC7289511
NM_014924KIAA08311
NM_005578LPP1
NM_021815SLC5A71
NM_032788ZNF5141
NM_0011132391
NM_022740HIPK21
NM_203395IYD1
NM_182508C13orf301
NM_005324H3F3B1
NM_003644GAS71
NM_201432GAS71
NM_201433GAS71
NM_018452C6orf351
NM_0011110391
NM_152736ZNF1871
NM_001023560ZNF1871
XM_496826NHSL11
XM_941807NHSL11
NM_005667RNF1031
NM_024818UBE1DC11
NM_198329UBE1DC11
NM_005096ZMYM31
NM_201599ZMYM31
NM_001080497MEGF91
XM_936860MEGF91
NM_012164FBXW21
NM_001017924LRRC221
NM_005909MAP1B1
XM_939547ZNF6971
NM_001080470ZNF6971
NM_006598SLC12A71
NM_015042ZNF6091
NM_018299UBE2W1
NM_001001481UBE2W1
NM_015137KIAA01431
NM_015071ARHGAP261
XM_945019LOC6434411
XM_933124LOC6434411
NM_005630SLCO2A11
NM_012193FZD41
NM_152519FLJ238611
NM_182757IBRDC21
NM_020826SYT131
NM_001040159SPOCK31
NM_016950SPOCK31
XM_001127175LOC7283201
NM_007158CSDE11
NM_001007553CSDE11
NM_020648TWSG11
NM_006814PSMF11
NM_178578PSMF11
NM_001530HIF1A1
NM_181054HIF1A1
NM_005417SRC1
NM_198291SRC1
NM_0010988051
NM_001012419ANKRD20A31
NM_001012421ANKRD20A21
NM_032250ANKRD20A11
NM_001029884PLEKHG11
NM_001024660KALRN1
NM_007064KALRN1
NM_080283ABCA91
NM_015477SIN3A1
NM_020150SAR1A1
NM_020796SEMA6A1
NM_012419RGS171
NM_016287HP1BP31
NM_080539COLQ1
NM_080538COLQ1
NM_080544COLQ1
NM_005677COLQ1
NM_080541COLQ1
NM_018015CXorf571
NM_005160ADRBK21
NM_030805LMAN2L1
NM_014257CLEC4M1
NM_214679CLEC4M1
NM_214678CLEC4M1
NM_214676CLEC4M1
NM_214677CLEC4M1
NM_016575NT5DC31
NM_020914RNF2131
NM_024612DHX401
XM_942276DHX401
NM_018361AGPAT51
NM_003048SLC9A21
NM_173670RGMB1
NM_024947PHC31
NM_032013NDRG31
NM_022477NDRG31
NM_005069SIM21
NM_001001669FLJ416031
XM_931553LOC6434491
XM_945026LOC6434491
NM_024843CYBRD11
NM_013279C11orf91
NM_006446SLCO1B11
NM_002467MYC1
NM_006778TRIM101
NM_052828TRIM101
NM_002025AFF21
XM_001133397LOC7293351
XM_001133821LOC7318541
NM_017662TRPM61
NM_001626AKT21
NM_133443GPT21
NM_198057TSC22D31
NM_001015881TSC22D31
NM_004089TSC22D31
NM_018157RIC8B1
NM_019044CCDC931
NM_017420SIX41
NM_178011LRRTM31
NM_004597SNRPD21
NM_177542SNRPD21
NM_0334031
NM_024885TAF7L1
NM_021637TMEM351
NM_014790JAKMIP21
NM_016617UFM11
NM_013322SNX101
NM_024834C10orf1191
NM_002787PSMA21
NM_134325SLC26A91
NM_052934SLC26A91
NM_133448TMEM132D1
XM_001126406LOC7279221
XM_001126391LOC7279221
XM_001126417LOC7279221
NM_054016FUSIP11
NM_003784SERPINB71
NM_001040147SERPINB71
NM_002358MAD2L11
NM_001008493ENAH1
NM_018212ENAH1
NM_015336ZDHHC171
NM_198836ACACA1
NM_198837ACACA1
NM_198834ACACA1
NM_198838ACACA1
NM_198839ACACA1
XM_373030LOC2855561
XM_939505LOC2855561
NM_001025233CLLU11
NM_020452ATP8B21
NM_000651CR11
NM_000573CR11
NM_015908ARS21
NM_182800ARS21
NM_001012642GRAMD21
NM_001204BMPR21
NM_020772NUFIP21
NM_005226EDG31
XM_938104LOC6450181
XM_930178LOC6450181
XM_001130184LOC7308431
XM_001130364LOC7284171
XM_379273FLJ141861
XM_001128891LOC7309531
NM_004571PKNOX11
NM_0011031471
NM_0011031481
NM_0011031461
NM_015575TNRC151
NM_018439IMPACT1
NM_175921LOC2856361
NM_004444EPHB41
NM_006922SCN3A1
NM_001081677SCN3A1
NM_001081676SCN3A1
NM_001035247UFD1L1
NM_005659UFD1L1
NM_032642WNT5B1
NM_030775WNT5B1
NM_006283TACC11
NM_144974CCDC1221
NM_001079526IKZF21
NM_016260IKZF21
NM_205846PRELID21
NM_138492PRELID21
NM_182960PRELID21
NM_203329CD591
NM_203331CD591
NM_203330CD591
NM_000611CD591
NM_001941DSC31
NM_024423DSC31
NM_020705TBC1D241
NM_139277KLK71
NM_005046KLK71
NM_005211CSF1R1
NM_032228MLSTD21
NM_001037165FOXK11
NM_030631SLC25A211
NM_004586RPS6KA31
NM_001201BMP31
NM_133370YTHDC11
NM_001031732YTHDC11
NM_013402FADS11
NM_000277PAH1
NM_000840GRM31
NM_001017364C4BPB1
NM_000716C4BPB1
NM_001017365C4BPB1
NM_001017367C4BPB1
NM_001017366C4BPB1
NM_015520MAGI11
NM_001033057MAGI11
NM_024080TRPM81
NM_016018PHF20L11
NM_006331EMG11
NM_1522831
NM_003626PPFIA11
NM_183416KIF1B1
NM_032679ZNF5771
NM_033160ZNF6581
NM_001032297ZNF658B1
NM_007357COG21
NM_152484ZNF5691
NM_003451ZNF1771
NM_001003407ABLIM11
NM_001003408ABLIM11
NM_002313ABLIM11
NM_006720ABLIM11
NM_015035ZHX31
NM_032804C10orf221
NM_024086METT10D1
NM_015450POT11
NM_001042594POT11
NM_004796NRXN31
NM_0011052501
NM_138970NRXN31
NM_003489NRIP11
NM_001044722CSNK1G31
NM_001031812CSNK1G31
NM_001044723CSNK1G31
NM_004384CSNK1G31
NM_006890CEACAM71
NM_017776ZNF6731
NM_018400SCN3B1
NM_001040151SCN3B1
NM_005156ROD11
NM_003189TAL11
NM_0010096101
NM_198152UTS2D1
NM_152277UBTD21
NM_0011045901
NM_0011045891
NM_0011045871
NM_152270SLFN111
NM_0011045881
NM_006631ZNF2661
NM_198058ZNF2661
NM_001080493HSZFP361
XM_936858HSZFP361
NM_198535ZNF6991
NM_170606MLL31
NM_003437ZNF1361
XM_001126650ZNF1361
XM_946265FHAD11
XM_934889FHAD11
NM_017694FLJ201601
XM_001130627LOC7295591
NM_000130F51
NM_001106ACVR2B1
NM_012106ARL2BP1
NM_014079KLF151
NM_022832USP461
NM_0010975991
NM_025246TMEM221
NM_0010976001
NM_014480ZNF5441
NM_021047ZNF2531
NM_001008494ISX1
NM_021627SENP21
NM_018121C10orf61
NM_138635H2AFV1
NM_003873NRP11
NM_015836WARS21
NM_175736FMNL31
NM_198900FMNL31
NM_004854CHST101
NM_001081573GAB31
NM_080612GAB31
XM_001131395LOC7298101
XM_001126629LOC7306341
NM_0011016761
NM_006241PPP1R21
NM_001039396MPEG11
NM_002843PTPRJ1
XM_001130068LOC7293691
NM_025190KIAA16411
NM_014048MKL21
NM_199169TMEPAI1
NM_199170TMEPAI1
NM_199171TMEPAI1
NM_020182TMEPAI1
NM_023943TMEM1081
NM_0011045861
NM_024744ALS2CR81
NM_002182IL1RAP1
NM_152665TCTEX1D11
NM_153688ZFP11
NM_198153TREML41
NM_033631LUZP11
NM_017952PTCD31
NM_172037RDH101
NM_0178921
NM_016132MYEF21
NM_006827TMED101
NM_001033723ZNF7041
NM_021648TSPYL41
NM_030641APOL61
NM_016644PRR161
NM_0010839621
NM_003199TCF41
NM_014744TBC1D51
NM_145005C9orf721
NM_014614PSME41
NM_198181LOC4402951
XM_929030LOC1615271
XM_933066LOC6436961
NM_006038SPATA21
XM_940430LOC6488521
NM_024817THSD41
NM_006329FBLN51
NM_198506FLJ446911
NM_004100EYA41
NM_172105EYA41
NM_172103EYA41
NM_000621HTR2A1
NM_017754C6orf1071
NM_005076CNTN21
NM_006029PNMA11
XM_941644LOC3998811
XM_929980LOC6470001
XM_941325LOC6520251
NM_001009899KIAA20181
NM_014309RBM91
NM_001082576RBM91
NM_001082577RBM91
NM_001031695RBM91
NM_001082578RBM91
NM_001082579RBM91
NM_152527SLC16A141
NM_177948ARMCX31
NM_177947ARMCX31
NM_016607ARMCX31
XM_001131068LOC7296961
XM_001129643LOC7314351
NM_153051MTMR31
NM_021090MTMR31
NM_153050MTMR31
NM_024298LENG41
NM_003161RPS6KB11
NM_030791SGPP11
NM_144571CNOT6L1
NM_025132WDR191
NM_001012965KLK61
NM_002774KLK61
NM_001012964KLK61
NM_030625CXXC61
XM_001131550LOC7298601
NM_181643C1orf881
NM_153029N4BP11
XM_934649C1orf341
XM_945958C1orf341
NM_033170B3GALT51
NM_033173B3GALT51
NM_033171B3GALT51
NM_006057B3GALT51
NM_033172B3GALT51
XM_001129796LOC6455131
NM_012069ATP1B41
NM_001080530LOC920171
NM_012474UCK21
NM_004540NCAM21
NM_014616ATP11B1
NM_012125CHRM51
NM_207577MAP61
NM_005540INPP5B1
NM_017957EPN31
NM_138727ST7L1
NM_138728ST7L1
NM_017744ST7L1
NM_017410HOXC131
NM_183425RBM381
NM_152787MAP3K7IP31
NM_000240MAOA1
NM_001004342TRIM671
NM_001080391SP1001
NM_014316CARHSP11
NM_001042476CARHSP11
NM_144599NIPA11
NM_000849GSTM31
NM_001077657C3orf431
NM_001025603RFX51
NM_000449RFX51
NM_001182ALDH7A11
NM_006628ARPP-191
NM_017980LIMS21
NM_020731AHRR1
NM_033100PCDH211
NM_015695BRPF31
NM_199425VSX11
NM_198698KRTAP12-41
NM_001007024GOSR11
NM_001007025GOSR11
NM_004871GOSR11
NM_005984SLC25A11
NM_022077MANBAL1
NM_001003897MANBAL1
NM_003988PAX21
NM_006274CCL191
NM_014411NAG81
NM_198460GBP61
NM_025058TRIM461
NM_016426GTSE11
NM_139158ALS2CR71
NM_145278C1orf1501
NM_001006656ZNF4731
NM_015428ZNF4731
NM_016606REEP21
NM_017747ANKHD11
NM_152670C2orf511
NM_001013693LDLRAD21
NM_080650ATPBD41
NM_0010986221
NM_0207211
NM_001094ACCN11
NM_183377ACCN11
NM_014742TM9SF41
NM_173526C14orf541
NM_175872ZNF7921
NM_138715MSR11
NM_138716MSR11
NM_000991RPL281
NM_022351EFCBP11
NM_003431ZNF1241
XM_937200RPTN1
NM_181836TMED71
NM_002998SDC21
NM_031426C9orf581
NM_173483FLJ395011
XM_001130012LOC7315471
XM_001129569LOC7291771
NM_002627PFKP1
XM_001132281LOC7287161
XM_001128614LOC7288451
NM_001005473PLCXD31
NM_006941SOX101
XM_001128489LOC7285771
NM_033655CNTNAP31
NM_006074TRIM221
NM_003298NR2C21
NM_000087CNGA11
NM_006682FGL21
NM_015686TMEM281
NM_198154TMEM951
NM_003428ZNF841
NM_025236RNF391
NM_170769RNF391
NM_030660ATXN31
NM_004993ATXN31
NM_004319ASTN11
NM_001001851ITIH51
XM_001132703FLJ410471
XM_001133280FLJ410471
NM_203372ACSL31
NM_004457ACSL31
NM_177403RAB7B1
NM_001360DHCR71
NM_022474MPP51
NM_022152TMBIM11
NM_000744CHRNA41
NM_014939KIAA10121
NM_0209111
NM_001012339DNAJA51
NM_194283DNAJA51
NM_006751SSFA21
NM_003245TGM31
NM_032429LZTS21
NM_020830WDFY11
NM_019894TMPRSS41
NM_0010839471
NM_000545TCF11
NM_006838METAP21
NM_004755RPS6KA51
NM_006380APPBP21
NM_133647SLC12A61
NM_001042495SLC12A61
NM_001042494SLC12A61
NM_001042497SLC12A61
NM_005135SLC12A61
NM_001042496SLC12A61
NM_015431TRIM581
NM_001494GDI21
NM_033542SYS11
NM_018252C1orf751
NM_004114FGF131
NM_024665TBL1XR11
NM_078474TM2D31
NM_025141TM2D31
NM_030806C1orf211
NM_002710PPP1CC1
NM_015265SATB21
NM_032849C13orf331
NM_022465IKZF41
NM_015631C10orf611
NM_018403DCP1A1
NM_0212431
NM_004279PMPCB1
NM_001040424PRDM151
NM_0011016691
NM_003866INPP4B1
NM_181342FKBP71
NM_004491GRLF11
NM_016173HEMK11
NM_033389SSH21
NM_182616C15orf381
NM_020148SPIRE11
NM_001044393MUC11
NM_016272TOB21
NM_015291DNAJC161
XM_001133837LOC7320991
XM_001133987LOC7296811
NM_0010986381
NM_021994ZNF277P1
NM_001031746C10orf721
NM_033211C5orf301
NM_1827627A51
NM_000798DRD51
NM_030962SBF21
NM_178129P2RY81
NM_006180NTRK21
NM_001018064NTRK21
NM_006624ZMYND111
NM_144582TEX2611
NM_003152STAT5A1
NM_001503GPLD11
NM_198715PTGER31
NM_006583RRH1
NM_207009FAM45A1
NM_003930SKAP21
NM_024689CXorf361
NM_199450ZNF3651
NM_025134CHD91
NM_025040ZNF6141
NM_006857RY11
NM_001527HDAC21
NM_000071CBS1
NM_002665PLGLB21
NM_001032392PLGLB11
NM_018280C22orf261
NM_030647JHDM1D1
NM_001040429PCDH171
NM_0010992941
XM_936510KIAA16441
NM_002332LRP11
NM_1526341
XM_938127ZNF6291
NM_001080417ZNF6291
NM_014959CARD81
NM_006080SEMA3A1
NM_016243CYB5R11
NM_002402MEST1
NM_177524MEST1
NM_177525MEST1
NM_152219GJC11
NM_018261EXOC11
NM_178237EXOC11
NM_001024924EXOC11
NM_007127VIL11
NM_004346CASP31
NM_032991CASP31
NM_006193PAX41
NM_012259HEY21
NM_130799MEN11
NM_130801MEN11
NM_000244MEN11
NM_130803MEN11
NM_130800MEN11
NM_130804MEN11
NM_130802MEN11
NM_006951TAF51
XM_001133616LOC7318801
XM_001128662LOC7281921
NM_004171SLC1A21
NM_016541GNG131
NM_182501MTERFD21
NM_032783CBR41
NM_003012SFRP11
NM_002508NID11
NM_0011001641
NM_0011001661
NM_014721PHACTR21
NM_0011001651
NM_005170ASCL21
NM_139279MCFD21
NM_020791TAOK11
NM_001003940BMF1
NM_001003943BMF1
NM_001003942BMF1
NM_033503BMF1
NM_024319C1orf351
NM_018085IPO91
NM_017944USP471
XM_942780SYNPO21
NM_006255PRKCH1
NM_024887DHDDS1
NM_205861DHDDS1
NM_012288TRAM21
NM_024884L2HGDH1
NM_144498OSBPL21
NM_014835OSBPL21
NM_000031ALAD1
NM_001003945ALAD1
NM_014977ACIN11
NM_025136OPA31
NM_005558LAD11
XM_001132383LOC7322531
NM_004296RGS61
NM_001040665STEAP21
NM_152999STEAP21
NM_004742MAGI11
NM_198935SS18L11
NM_017736THUMPD11
NM_018313PBRM11
NM_181042PBRM11
NM_018165PBRM11
NM_181742ORC4L1
NM_002552ORC4L1
NM_181741ORC4L1
NM_138440VASN1
NM_012400PLA2G2D1
NM_022733SMAP1L1
XM_944898LOC6517381
NM_212467CAPN31
NM_207428C11orf551
NM_032415CARD111
NM_022144TNMD1
NM_152247CPT1B1
NM_016321RHCG1
NM_001035235SRA11
NM_018196TMLHE1
NM_012320LYPLA31
XM_001134463BAHCC11
NM_001080519BAHCC11
NM_033064ATCAY1
NM_000135FANCA1
NM_004455EXTL11
NM_017588WDR51
NM_052821WDR51
NM_005902SMAD31
XM_940667SDC31
NM_183241C9orf1421
NM_000320QDPR1
NM_001034833NOLA21
NM_000878IL2RB1
NM_133493CD1091
NM_000129F13A11
NM_001008657TCOF11
NM_015020PHLPPL1
NM_005603ATP8B11
NM_016055MRPL481
NM_032632PAPOLA1
NM_020144PAPOLB1
NM_032826SLC35B41
NM_183397PXMP41
NM_007238PXMP41
NM_024758AGMAT1
NM_024811FLJ125291
NM_000544TAP21
NM_017848FAM120C1
NM_001010000ARHGAP281
NM_005862STAG11
NM_015091KIAA04231
NM_001012958DISC11
XM_001131702LOC1527421
XM_001128848LOC1527421
NM_014554SENP11
NM_002148HOXD101
NM_144693ZNF5581
NM_024770METTL81
NM_005962MXI11
NM_001008541MXI11
NM_130439MXI11
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_006210PEG31
NM_014594ZNF354C1
NM_002577PAK21
NM_001010903DKFZp779B15401
NM_032276RHBDD11
NM_015381FAM19A51
NM_001082967FAM19A51
NM_001033518WIPI21
NM_001033519WIPI21
NM_015610WIPI21
NM_001033520WIPI21
NM_016003WIPI21
NM_001007536AKR1CL11
NM_032341DDI21
NM_003281TNNI11
NM_025235TNKS21
XM_001132080LOC7310071
NM_203464AK3L11
NM_013410AK3L11
NM_001005353AK3L11
XM_928632LOC6456191
NM_006033LIPG1
NM_022780RMND5A1
NM_001011720XKR91
NM_002547OPHN11
NM_001011552SLC9A41
NM_004464FGF51
NM_033143FGF51
NM_016206VGLL31
NM_004232SOCS61
NM_002247KCNMA11
NM_001402EEF1A11
NM_017438SETD41
NM_057175NARG11
NM_025205MED281
NM_0152761
NM_021148ZNF2731
NM_152916EMR21
NM_152918EMR21
NM_152917EMR21
NM_152920EMR21
NM_152921EMR21
NM_013447EMR21
NM_152919EMR21
NM_025189ZNF4301
NM_152355ZNF4411
NM_020980AQP91
NM_001033578SGK31
NM_013257SGK31
NM_170709SGK31
NM_005934MLLT11
NM_000831GRIK31
NM_144585SLC22A121
NM_153378SLC22A121
NM_020734FAM80B1
NM_199188LARP41
NM_052879LARP41
NM_199190LARP41
NM_138396MARCH91
NM_004744LRAT1
NM_003714STC21
NM_001012756ZNF2601
NM_003387WIPF11
NM_001077269WIPF11
NM_005034POLR2K1
NM_007114TMF11
NM_0011006071
NM_016186SERPINA101
NM_006252PRKAA21
NM_020962NOPE1
NM_014961RUFY31
NM_005121THRAP11
NM_022817PER21
NM_016584IL23A1
NM_020919ALS21
NM_172177MRPL421
NM_172178MRPL421
NM_014050MRPL421
NM_015713RRM2B1
NM_007038ADAMTS51
NM_001033930UBA521
NM_003333UBA521
NM_022097LOC639281
NM_012072CD931
NM_080685PTPN131
NM_080683PTPN131
NM_006264PTPN131
NM_080684PTPN131
NM_018933PCDHB131
NM_032446MEGF101
NM_0010976361
NM_0010976341
NM_0010976351
NM_001490GCNT11
NM_0010976331
NM_032246RKHD31
NM_032828ZNF5871
NM_152475ZNF4171
NM_014848SV2B1
NM_013444UBQLN21
NM_023016ANKRD571
NM_001010923C6orf1901
NM_001077394DPH51
NM_001077395DPH51
NM_015958DPH51
NM_001077244GRIA41
NM_0011128121
NM_001037325CCDC461
NM_145036CCDC461
NM_014331SLC7A111
NM_018283NUDT151
NM_207585IFNAR21
NM_001753CAV11
NM_014315KLHDC21
NM_001039935ANKRD551
NM_024669ANKRD551
NM_003920TIMELESS1
NM_0011056591
NM_001040102TMEM101
NM_033207TMEM101
NM_001040103TMEM101
NM_001080412ZBTB381
XM_001133510ZBTB381
NM_004973JARID21
NM_004557NOTCH41
NM_021067GINS11
NM_0011013961
NM_001066TNFRSF1B1
NM_178457C20orf1741
NM_001077203SENP71
NM_020654SENP71
NM_014405CACNG41
NM_004801NRXN11
NM_138735NRXN11
NM_198887NUP431
NM_022787NMNAT11
NM_015285WDR71
NM_052834WDR71
NM_005066SFPQ1
NM_006564CXCR61
XM_001129552LOC7291731
NM_006591POLD31
NM_212479ZMYND111
NM_145309LRRC511
NM_153045C9orf911
NM_003262TLOC11
NM_022166XYLT11
XM_001125986LOC2838241
NM_0121941
NM_004494HDGF1
NM_0010992871
NM_014872ZBTB51
NM_014741KIAA06521
NM_000217KCNA11
NM_006152LRMP1
NM_001018058TFEC1
NM_012252TFEC1
NM_001010908C1QL31
NM_017671C20orf421
NM_001009992ZNF6481
NM_018640LMO31
NM_001001395LMO31
NM_014646LPIN21
NM_139014MAPK141
NM_005935AFF11
NM_014181HSPC1591
NM_015578LSM14A1
NM_014043CHMP2B1
NM_007231SLC6A141
XM_936869LOC1238761
NM_0011004271
NM_021159RAP1GDS11
NM_0011004281
NM_0011004291
NM_0011004261
NM_0011004301
NM_014783ARHGAP11A1
NM_030568C6orf1481
NM_007057ZWINT1
NM_032997ZWINT1
NM_001005413ZWINT1
NM_020375C12orf51
NM_002609PDGFRB1
NM_001012761RGMB1
NM_017902HIF1AN1
XM_001130949LOC1583761
XM_001129749LOC1583761
NM_0011004211
NM_0011004201
NM_017447C21orf911
NM_001080415SR1401
XM_940802SR1401
NM_003744NUMB1
NM_001005745NUMB1
NM_001005744NUMB1
NM_001005743NUMB1
NM_020386HRASLS1
NM_133264WIPF21
XM_929331LOC6464051
XM_940374LOC6512391
NM_006620HBS1L1
NM_021049MAGEA51
NM_001077497PRR31
NM_025263PRR31
NM_000428LTBP21
NM_005562LAMC21
NM_0245241
NM_001037131CENTG21
NM_014914CENTG21
NM_024709C1orf1151
XM_371369MIA31
XM_943876MIA31
XM_943869MIA31
XM_943873MIA31
XM_496436MIA31
XM_932541MIA31
XM_932548MIA31
NM_198551MIA31
NM_005554KRT6A1
NM_021132PPP3CB1
NM_021940SMAP11
NM_001044305SMAP11
NM_019088PAF11
NM_138348FAM105B1
NM_001526HCRTR21
NM_0209231
XM_943399LOC6432811
XM_931461LOC6432811
NM_021814ELOVL51
NM_018899PCDHAC21
NM_018900PCDHA11
NM_018902PCDHA111
NM_031849PCDHA61
NM_018905PCDHA21
NM_018904PCDHA131
NM_031860PCDHA101
NM_018907PCDHA41
NM_018909PCDHA61
NM_018910PCDHA71
NM_018911PCDHA81
NM_018906PCDHA31
NM_018903PCDHA121
NM_018898PCDHAC11
NM_031857PCDHA91
NM_031411PCDHA11
NM_018908PCDHA51
NM_018901PCDHA101
XM_941142FTO1
NM_001080432FTO1
NM_014600EHD31
NM_004857AKAP51
XM_929573LOC6537681
NM_013250ZNF2151
NM_002664PLEK1
NM_206963RARRES11
XM_934271LOC3882371
NM_001018122LOC4403501
XM_001132780LOC7287341
XM_001132813LOC7287411
NM_003240LEFTY21
NM_002490NDUFA61
NM_024516C16orf531
NM_001039362ATP6V1C21
NM_144583ATP6V1C21
NM_001010845LOC1238761
NM_018132CENPQ1
NM_182515ZNF7141
NM_018141MRPS101
NM_001004317LIN28B1
NM_024627C22orf291
NM_145863ASB31
NM_016115ASB31
XM_001133595LOC7293241
XM_001133813LOC7317571
NM_001042508LOC6534831
NM_001002811PDE4DIP1
NM_001002812PDE4DIP1
XM_001126165LOC7279271
NM_0011102131
NM_005042PRH21
NM_144649TMEM711
NM_000243MEFV1
NM_015557CHD51
NM_001037535SCML11
NM_001037540SCML11
NM_006746SCML11
NM_001037536SCML11
NM_021964ZNF1481
NM_018129PNPO1
NM_032439PHYHIPL1
NM_016605FAM53C1
NM_003274TMEM11
NM_152739HOXA91
NM_175856CHSY-21
NM_005826HNRPR1
NM_0011023981
NM_0011023971
NM_0011023991
NM_002033FUT41
NM_031244SIRT51
NM_175910ZNF4931
NM_001076678ZNF4931
NM_213598ZNF5431
XM_001126816LOC7306921
XM_001130552LOC7295431
NM_001177ARL11
NM_006915RP21
NM_001029874REP151
NM_018441PECR1
NM_032731TXNL51
NM_005870SAP181
NM_001497B4GALT11
NM_024738C12orf491
NM_018375SLC39A91
NM_153256C10orf471
NM_001001561GGA11
XM_291671RBM201
XM_939337RBM201
NM_001031711ERGIC11
NM_0529271
NM_0208461
NM_198844ZPBP21
NM_199321ZPBP21
NM_178161PTF1A1
NM_015567SLITRK51
XM_001134369LOC7301071
NM_004483GCSH1
XM_945736LOC6540851
NM_013371IL191

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317