Predicted Off-targets for siRNA "ucuggucguguuaaugacu" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

7 hits were found for UCUGGUCGUGUUAAUGACU (5 guide strand hits and 2 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_003794 SNX4 1532 1550 UgUGGUCGUGUUAAUGuag57 4 14 ac false   <90%   2567
NM_018833 TAP2 639 657 UCUGGUCGUGUgAuUGACa41 3 11   false   <90%   2540
NM_000544 TAP2 639 657 UCUGGUCGUGUgAuUGACa41 3 11   false   <90%   5679
NM_005546 ITK 3555 3573 cuUGGUCaUGUUAAUGACU24 3 11 bc false   <90%   4366
NM_005513 GTF2E1 2984 3002 cugGGUuGUGUUAAUGACU0 4 12 bc false   <90%   3033


Hits to Sense strand



AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
XR_018175 LOC646583 336 354 cagCAUUAACAaGACCAGA33 4 8   false   <90%   835
XR_017223 LOC646583 336 354 cagCAUUAACAaGACCAGA33 4 8   false   <90%   835


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1672
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_005934MLLT13
NM_015090NFASC3
NM_014388C1orf1073
NM_004171SLC1A23
NM_138413C10orf653
NM_001039709CBFA2T23
NM_001032999CBFA2T23
NM_005093CBFA2T23
NM_173598KSR23
NM_198560LHFPL43
NM_002375MAP43
NM_030884MAP43
NM_024086METT10D3
NM_004976KCNC13
NM_175736FMNL33
NM_198900FMNL33
NM_016448DTL2
NM_019885CYP26B12
NM_017848FAM120C2
NM_030627CPEB42
NM_006852TLK22
NM_0011127072
NM_145177DHRSX2
NM_007011ABHD22
NM_152924ABHD22
NM_015039NMNAT22
NM_170706NMNAT22
NM_032445MEGF112
NM_015299KIAA03232
NM_133493CD1092
XM_496436MIA32
XM_932541MIA32
XM_932548MIA32
XM_371369MIA32
XM_943876MIA32
XM_943869MIA32
XM_943873MIA32
NM_176871PDLIM22
NM_021079NMT12
NM_032193RNASEH2C2
NM_001037165FOXK12
NM_015995KLF132
NM_004840ARHGEF62
NM_0010937252
NM_152680TMEM1542
NM_017849TMEM1272
NM_017921NPLOC42
NM_006504PTPRE2
NM_130435PTPRE2
NM_031899GORASP12
NM_033656BRWD12
NM_019899ABCC12
NM_019862ABCC12
NM_019898ABCC12
NM_004996ABCC12
NM_019900ABCC12
NM_0010853752
NM_020981B3GALT12
NM_0010986272
NM_032643IRF52
NM_002200IRF52
NM_0010986312
NM_0010986292
NM_0010986282
NM_0010986302
NM_145166ZBTB472
NM_014747RIMS32
NM_001010980C1orf1302
NM_017637BNC22
NM_001001420SMAD52
NM_001001419SMAD52
NM_005903SMAD52
NM_021961TEAD12
NM_017902HIF1AN2
XM_942780SYNPO22
NM_001040285PAPD52
NM_001040284PAPD52
NM_0011031472
NM_0011031482
NM_0011031462
NM_015575TNRC152
NM_018449UBAP22
NM_003043SLC6A62
NM_030648SETD72
NM_001005505CACNA2D22
NM_006030CACNA2D22
NM_024345WDR322
NM_024577SH3TC22
NM_016079VPS242
NM_001005753VPS242
NM_001014809CRMP12
NM_001313CRMP12
NM_019074DLL42
NM_194286KIAA18532
NM_015077SARM12
NM_1827627A52
NM_004992MECP22
NM_015338ASXL12
NM_002351SH2D1A2
NM_173065IL28RA2
NM_006306SMC1A2
NM_021138TRAF22
NM_031904FKSG442
NM_016201AMOTL22
NM_014772KIAA04272
NM_001012478U2AF22
NM_007279U2AF22
NM_020438DOLPP12
NM_181789GLDN2
NM_021943ZFAND32
NM_015332NUDCD32
NM_022497MRPS252
NM_025000C2orf372
NM_001040709SYPL22
NM_212467CAPN32
NM_000723CACNB12
XM_001134172LOC7300342
XM_001133186LOC7313452
NM_201520SLC25A352
NM_153022C12orf592
NM_020133AGPAT42
NM_015059TLN22
XM_001125737LOC7302752
NM_001025108AFF32
NM_002285AFF32
NM_0152972
NM_148170CTSC2
XM_001131981LOC7321412
XM_001128551LOC7288162
NM_145313RASGEF1A2
NM_003724JRK2
NM_022061MRPL172
NM_003926MBD32
NM_002688SEPT52
NM_014042C11orf512
NM_001024843TNRC6B2
NM_015088TNRC6B2
NM_016340RAPGEF62
NM_017415KLHL32
NM_002241KCNJ102
NM_020746VISA2
NM_139278LGI32
NM_004386NCAN2
NM_177405CECR12
NM_017424CECR12
NM_005160ADRBK22
NM_012334MYO102
NM_014946SPAST2
NM_199436SPAST2
NM_030927TSPAN142
NM_133478SLC4A51
NM_178457C20orf1741
XM_049078KIAA12391
XM_940885KIAA12391
NM_016575NT5DC31
NM_015353KCTD21
NM_020412CHMP1B1
NM_000435NOTCH31
NM_021216ZNF711
NM_014279OLFM11
NM_002978SCNN1D1
NM_014849SV2A1
NM_016332SEPX11
NM_002864PZP1
NM_000902MME1
NM_007289MME1
NM_007288MME1
NM_007287MME1
NM_001639APCS1
NM_021130PPIA1
NM_152261C12orf231
NM_030962SBF21
NM_023016ANKRD571
NM_001013659ZNF7931
NM_198269HIPK11
NM_181358HIPK11
NM_198268HIPK11
NM_148174AZIN11
NM_015878AZIN11
NM_000875IGF1R1
NM_021949ATP2B31
NM_001001344ATP2B31
NM_018411HR1
NM_005144HR1
NM_001040280CD831
NM_004233CD831
NM_022470ZMAT31
NM_152240ZMAT31
NM_022351EFCBP11
NM_198353KCTD81
NM_000351STS1
NM_033296MRFAP11
NM_144767AKAP131
NM_006738AKAP131
NM_007200AKAP131
XM_944198LOC4002361
XM_378472LOC4002361
NM_001235SERPINH11
NM_022334ITGB1BP11
NM_004763ITGB1BP11
NM_0010985031
NM_001077418FLJ221671
NM_001077416FLJ221671
NM_001077419FLJ221671
NM_0010996461
NM_152908MATE21
NM_001031684SFRS71
NM_001005210LRRC551
NM_021977SLC22A31
NM_024535CORO71
NM_003722TP73L1
NM_182503DEADC11
NM_001031700C4orf181
NM_016613C4orf181
NM_018662DISC11
NM_001012957DISC11
NM_013402FADS11
NM_004114FGF131
NM_033642FGF131
NM_004559YBX11
NM_012310KIF4A1
NM_004078CSRP11
NM_015670SENP31
NM_004826ECEL11
NM_001039656MTL51
NM_001007156NTRK31
NM_032727INA1
NM_199421SOCS41
NM_080867SOCS41
NM_182970RIMS41
NM_000014A2M1
NM_014912CPEB31
XM_001125792LOC7278341
XM_926013LOC6423981
NM_002177IFNW11
NM_001003652SMAD21
NM_005901SMAD21
NM_001042601TTC141
NM_019604CRTAM1
NM_198551MIA31
NM_153273IHPK11
NM_001006115IHPK11
NM_000397CYBB1
NM_030885MAP41
NM_007049BTN2A11
NM_078476BTN2A11
NM_145341PDCD41
NM_014456PDCD41
NM_005938MLLT71
NM_003274TMEM11
NM_198849LOC2835141
NM_021194SLC30A11
NM_001018050POLR3H1
NM_138338POLR3H1
NM_001018052POLR3H1
NM_024742ARMC51
NM_153023SPATA131
NM_173509C1orf761
NM_002885RAP1GAP1
NM_173476CCDC781
NM_020447C15orf171
NM_0212411
NM_021996GBGT11
NM_012215MGEA51
NM_153341IBRDC31
NM_207330NPAL11
NM_018332DDX19A1
NM_005927MFAP31
NM_001003891PCQAP1
NM_015889PCQAP1
NM_024032C17orf531
NM_203350ZRANB21
NM_005455ZRANB21
NM_006340BAIAP21
NM_015055SWAP701
NM_001001894TTC31
NM_003316TTC31
NM_017757ZNF4071
NM_002077GOLGA11
NM_024887DHDDS1
NM_205861DHDDS1
NM_022153C10orf541
NM_020705TBC1D241
NM_021970MAP2K1IP11
NM_004863SPTLC21
NM_145230ATP6V0E21
NM_181351NCAM11
NM_000615NCAM11
NM_014707HDAC91
NM_134445CD99L21
NM_134446CD99L21
NM_031462CD99L21
NM_198484ZNF6211
NM_0010984141
NM_153347TMEM86A1
NM_020243TOMM221
NM_014240LIMD11
NM_005027PIK3R21
XM_925864LOC6423251
NM_025104DBF4B1
NM_194272RBPMS21
NM_001038707CDC42SE11
NM_020239CDC42SE11
NM_130807MOBKL2A1
NM_020750XPO51
NM_002248KCNN11
NM_014325CORO1C1
NM_014828TOX41
NM_014376CYFIP21
NM_001037332CYFIP21
NM_001037333CYFIP21
NM_183419RNF191
NM_015435RNF191
NM_006873STON11
NM_015288PHF151
NM_058180C21orf581
NM_006995BTN2A21
NM_181531BTN2A21
NM_015058KIAA05641
NM_002993CXCL61
NM_000046ARSB1
NM_007047BTN3A21
NM_001248ENTPD31
NM_005189CBX21
NM_004274AKAP61
NM_0010981991
NM_005279GPR11
NM_176825SULT1C21
NM_001056SULT1C21
NM_003417ZNF2641
NM_015477SIN3A1
NM_001008737LOC4010521
NM_0011055181
NM_017673C1orf261
NM_001080745DGKG1
NM_001346DGKG1
NM_001080744DGKG1
NM_133264WIPF21
NM_0010987871
NM_016526BET1L1
NM_033274ADAM191
NM_001077401ACVRL11
NM_000020ACVRL11
NM_024785FAM124B1
NM_014734KIAA02471
NM_015226KIAA03501
NM_017755NSUN21
NM_018330KIAA15981
NM_016466ANKRD391
NM_001455FOXO3A1
NM_201559FOXO3A1
NM_144579SFXN51
NM_019089HES21
NM_152753SCUBE31
NM_025090USP361
NM_181844BCL6B1
NM_0321731
NM_014048MKL21
NM_015912C8ORFK321
NM_016231NLK1
NM_000600IL61
NM_020859SHROOM31
NM_0011016671
NM_003501ACOX31
NM_024915GRHL21
NM_138992BACE21
NM_130848C5orf201
NM_024843CYBRD11
NM_004716PCSK71
XM_001128785LOC7311961
XM_938842LOC6533031
NM_148960CLDN191
NM_001031702SEMA5B1
NM_138328RHBDL31
NM_022152TMBIM11
NM_016733LIMK21
NM_005569LIMK21
NM_006113VAV31
NM_001079874VAV31
NM_003757EIF3S21
NM_183237RNF71
NM_014245RNF71
NM_024627C22orf291
NM_0121941
NM_021007SCN2A1
NM_001040142SCN2A1
NM_001040143SCN2A1
NM_001008493ENAH1
NM_018212ENAH1
NM_003471KCNAB11
NM_172159KCNAB11
NM_172160KCNAB11
NM_015894STMN31
NM_001008390CGGBP11
NM_003663CGGBP11
NM_013397C6orf491
NM_005599NHLH21
NM_0011110611
NM_007147ZNF1751
NM_004157PRKAR2A1
NM_182612PDDC11
NM_207395ZNF324B1
NM_138959VANGL11
NM_015503SH2B11
NM_139265EHD41
NM_014675CROCC1
NM_004685MTMR61
NM_001018112FANCA1
NM_021925C2orf431
NM_138694PKHD11
NM_001038633RSPO11
NM_002857PEX191
NM_018425PI4KII1
NM_007176C14orf11
NM_006621AHCYL11
NM_152356ZNF4911
NM_015329KIAA08921
NM_001013842C8orf581
NM_198281GPRIN31
NM_005526HSF11
XM_001127807LOC6422551
XM_001126718LOC6422551
NM_182597FLJ395751
NM_0010994041
NM_198056SCN5A1
NM_0010994051
NM_000335SCN5A1
NM_000877IL1R11
NM_025222TMEM1131
NM_001039887C19orf551
NM_001031681CTNS1
NM_004937CTNS1
NM_032361THOC31
XM_001133439THOC31
NM_006774INMT1
NM_018346RSAD11
NM_014323PATZ11
NM_032052PATZ11
NM_032050PATZ11
NM_032807FBXO181
NM_178150FBXO181
NM_181489ZNF4451
NM_020312COQ91
NM_013372GREM11
NM_024554PGBD51
NM_005436CCDC61
NM_018199EXDL21
NM_020362C1orf1281
NM_172370DAOA1
NM_005795CALCRL1
NM_024620ZNF3291
NM_182485CPEB21
NM_182646CPEB21
NM_005570LMAN11
NM_006823PKIA1
NM_181839PKIA1
NM_001039395C9orf681
NM_001029864KIAA17551
NM_176823S100A7A1
NM_178128FADS61
NM_003485GPR681
NM_003179SYP1
NM_002112HDC1
NM_001106ACVR2B1
NM_006196PCBP11
NM_001012993C9orf1521
NM_012257HBP11
NM_138770CCDC74A1
NM_207310CCDC74B1
NM_001031617COX191
NM_014424HSPB71
NM_015168C19orf71
NM_001081455P2RY141
NM_014879P2RY141
NM_007006NUDT211
NM_005624CCL251
NM_198549FAM73A1
NM_000328RPGR1
NM_001029883FLJ349311
NM_002868RAB5B1
NM_001002860BTBD71
NM_032864PRPF38A1
NM_003856IL1RL11
NM_016472C14orf1291
NM_020405PLXDC11
XM_499348MGC573591
NM_152309PIK3AP11
NM_032383HPS31
NM_005910MAPT1
NM_016841MAPT1
NM_016834MAPT1
NM_016835MAPT1
NM_000929PLA2G51
NM_004321KIF1A1
NM_006467POLR3G1
NM_000202IDS1
NM_207444FLJ356951
NM_032822FLJ146681
NM_001001874TPD52L31
NM_001831CLU1
NM_203339CLU1
NM_020347LZTFL11
NM_018660ZNF3951
NM_006036PREPL1
NM_001042386PREPL1
NM_001042385PREPL1
NM_153229TMEM921
NM_021267LASS11
NM_002074GNB11
NM_032532FNDC11
NM_0148311
NM_003979GPRC5A1
NM_144994ANKRD231
NM_000719CACNA1C1
NM_018132CENPQ1
NM_152448C15orf431
NM_015046SETX1
NM_002829PTPN31
NM_002025AFF21
NM_000368TSC11
NM_032102SFRS2B1
NM_053046EGLN21
NM_080732EGLN21
XM_928077LOC6450151
NM_173084TRIM591
NM_021945C6orf851
XM_001133099LOC3398791
XM_291054LOC3398791
XM_930103LOC6449741
XM_941316LOC6495911
XM_001127597FLJ328101
XM_001127587FLJ328101
XM_925815FLJ328101
XM_001127637FLJ328101
XM_001127623FLJ328101
NM_0011003981
NM_015085GARNL41
NM_016298FBXO401
NM_015458MTMR91
NM_014859KIAA06721
NM_033267IRX21
NM_015330SPECC1L1
NM_004738VAPB1
NM_002639SERPINB51
NM_032547SCOC1
NM_021067GINS11
NM_001037293PALM21
NM_053016PALM21
NM_000439PCSK11
XM_942428DUSP271
NM_001080426DUSP271
NM_016076C1orf1211
NM_198066GNPNAT11
NM_015328KIAA08281
NM_001944DSG31
NM_016018PHF20L11
NM_016132MYEF21
NM_006635ZNF4601
NM_017709FAM46C1
NM_016500CXorf261
NM_017669FLJ201051
NM_182739NDUFB61
NM_002493NDUFB61
NM_014924KIAA08311
NM_014049ACAD91
NM_005188CBL1
XM_097977FAM59B1
XM_940578FAM59B1
NM_152388ALS2CR41
NM_001044385ALS2CR41
NM_016075VPS361
NM_024779PIP5K2C1
NM_0011055731
NM_019087ARL151
NM_020783SYT41
NM_173470TMEM321
NM_002581PAPPA1
XM_001133777LOC7295161
NM_001012276PRAMEF81
NM_020651PELI11
NM_001080830PRAMEF121
NM_006591POLD31
NM_138768MYEOV1
NM_133448TMEM132D1
NM_020144PAPOLB1
NM_001677ATP1B11
NM_017816LYAR1
NM_207361FREM21
NM_015553PIP3-E1
NM_001012415SOHLH11
NM_024013IFNA11
NM_177996EPB41L11
NM_012156EPB41L11
NM_152906C22orf251
NM_1522931
NM_182935MOBP1
NM_001003828PARVB1
NM_013327PARVB1
NM_213566DFFA1
NM_001010891MTX31
NM_022899ACTR81
NM_000084CLCN51
NM_014677RIMS21
NM_0011001171
NM_0151771
NM_152914MGC338941
NM_014286FREQ1
NM_001172ARG21
NM_144972LDHAL6A1
NM_003385VSNL11
NM_025219DNAJC51
NM_014873LPGAT11
NM_032853MUM11
NM_003038SLC1A41
NM_025010KLHL181
NM_032287LDOC1L1
NM_012304FBXL71
NM_005840SPRY31
NM_032219MFSD71
NM_001310CREBL21
NM_015352POFUT11
NM_001447FAT21
XM_938194LOC1276021
XM_059166LOC1276021
NM_032377ELOF11
NM_198381ELF51
NM_001422ELF51
NM_021082SLC15A21
NM_007097CLTB1
NM_001834CLTB1
NM_001711BGN1
NM_001481GAS81
NM_004497FOXA31
NM_001754RUNX11
NM_001001890RUNX11
NM_0011055431
NM_015645C1QTNF51
NM_144682SLFN131
NM_005417SRC1
NM_198291SRC1
NM_021615CHST61
XM_946336LOC1464291
XM_370997LOC1464291
NM_001001561GGA11
NM_0011031701
NM_0011031691
NM_003657BCAS11
NM_005156ROD11
NM_025128MUS811
NM_006926SFTPA21
NM_0010986681
NM_021932RIC8A1
NM_031439SOX71
NM_002996CX3CL11
NM_002314LIMK11
NM_003966SEMA5A1
NM_012307EPB41L31
XM_001134308LOC7322751
NM_207348SLC25A341
NM_002442MSI11
NM_006788RALBP11
NM_022143LRRC41
NM_144679C17orf561
NM_015840ADAR1
NM_015841ADAR1
NM_001025107ADAR1
NM_001111ADAR1
NM_001010867C1orf691
NM_018191RCBTB11
NM_0011055291
NM_006095ATP8A11
NM_000721CACNA1E1
NM_003458BSN1
NM_183397PXMP41
NM_007238PXMP41
NM_005140CNGA21
NM_024523GCC11
NM_002334LRP41
NM_181672OGT1
NM_181673OGT1
NM_016485VTA11
NM_178818CMTM41
NM_181521CMTM41
NM_206595ESRRG1
NM_001438ESRRG1
NM_206594ESRRG1
NM_003049SLC10A11
NM_001031711ERGIC11
NM_002657PLAGL21
XM_001130184LOC7308431
XM_001130364LOC7284171
NM_024894NOL101
NM_001987ETV61
NM_052869TTYH21
NM_032646TTYH21
NM_144965TTC161
NM_145912NFAM11
NM_005601NKG71
NM_005440RND21
NM_024306FA2H1
NM_203316DPAGT11
NM_001382DPAGT11
NM_031444C22orf131
XM_001133059LOC7287721
XM_001133074LOC7287721
XM_001133066LOC7287721
NM_145041TMEM106A1
NM_014698TMEM63A1
NM_000815GABRD1
NM_145807LOC1261471
NM_032808LINGO11
NM_172367TUSC51
NM_194291TMEM651
NM_012079DGAT11
NM_006569CGREF11
NM_032414PROK11
NM_199423WWP21
NM_206866BACH11
NM_001186BACH11
NM_018401STK32B1
NM_018210FLJ107691
NM_0010986381
NM_138727ST7L1
NM_138728ST7L1
NM_017744ST7L1
XM_001130919LOC7296521
NM_014232VAMP21
NM_002747MAPK41
NM_004055CAPN51
NM_002309LIF1
NM_148911CHRFAM7A1
NM_139320CHRFAM7A1
NM_176787PIGN1
NM_012327PIGN1
NM_139319SLC17A81
NM_021202TP53INP21
NM_172169CAMK2G1
NM_001222CAMK2G1
NM_172173CAMK2G1
NM_172171CAMK2G1
NM_172170CAMK2G1
NM_020904PLEKHA41
NM_002417MKI671
NM_014850SRGAP31
NM_001033117SRGAP31
NM_014809KIAA03191
NM_138795ARL8A1
NM_001441FAAH1
NM_032803SLC7A31
NM_001048164SLC7A31
NM_002716PPP2R1B1
NM_002086GRB21
NM_203506GRB21
NM_0010996921
XM_926071LOC6425921
NM_001970EIF5A1
NM_001039697SNAPC31
NM_007286SYNPO1
NM_053064GNG21
XM_001128325LOC2834811
XM_001133584LOC2834811
NM_001024071GCH11
NM_001024024GCH11
NM_001024070GCH11
NM_000161GCH11
NM_138619GGA31
NM_014001GGA31
NM_015465GEMIN51
NM_174892CD300LB1
NM_178584SEPT101
NM_144710SEPT101
NM_024837ATP8B41
NM_018028SAMD4B1
NM_005935AFF11
XM_934649C1orf341
XM_945958C1orf341
NM_004852ONECUT21
NM_133367PAQR81
NM_022465IKZF41
NM_024787RNF1221
NM_005430WNT11
NM_0010992941
XM_936510KIAA16441
NM_021163RBAK1
NM_001029939ZFAT11
NM_002698POU2F21
NM_014965TRAK11
NM_206833CTXN11
NM_058192RPUSD11
NM_031231APBA2BP1
NM_031232APBA2BP1
NM_005402RALA1
NM_015545PTCD11
NM_033386MICALL11
NM_015381FAM19A51
NM_001082967FAM19A51
NM_001035534FAM129B1
NM_022833FAM129B1
NM_024771NAT111
NM_022336EDAR1
NM_004878PTGES1
NM_001939DRP21
NM_172020POM1211
XM_001128149LOC7303161
XM_001129924LOC7293161
NM_0010994151
NM_138578BCL2L11
NM_001191BCL2L11
NM_015040PIP5K31
NM_002567PEBP11
NM_199296THSD31
NM_182509THSD31
NM_199265THSD31
NM_021116ADCY11
NM_018992KCTD51
NM_001451FOXF11
NM_173089CAPN31
NM_173090CAPN31
NM_173088CAPN31
NM_212465CAPN31
NM_212464CAPN31
NM_000070CAPN31
NM_024344CAPN31
NM_173087CAPN31
NM_006943SOX121
NM_016488PPHLN11
NM_001804CDX11
NM_203497COMMD61
NM_203495COMMD61
NM_003015SFRP51
NM_000578SLC11A11
NM_004624VIPR11
NM_0011101991
NM_0010984151
NM_016596HDAC7A1
NM_0010984161
NM_015401HDAC7A1
NM_005672PSCA1
NM_000436OXCT11
NM_145321OSBPL31
NM_145320OSBPL31
NM_145322OSBPL31
NM_015550OSBPL31
NM_152376UBXD31
NM_002638PI31
NM_001690ATP6V1A1
NM_030812ACTL81
NM_000551VHL1
NM_198156VHL1
NM_001760CCND31
NM_0010994321
NM_017679BCAS31
NM_006177NRL1
NM_015443KIAA12671
NM_001029871RSPO41
NM_001040007RSPO41
NM_021201MS4A71
NM_206938MS4A71
NM_206940MS4A71
NM_206939MS4A71
NM_003430ZNF911
NM_013385PSCD41
NM_021248CDH221
NM_015633FGFR1OP21
NM_014956CEP1641
NM_0010987901
NM_021242MID1IP11
NM_0010987911
NM_203374ZNF7841
NM_212533ABCA21
NM_001606ABCA21
NM_001080437SNED11
XM_940984SNED11
NM_207511C9orf1391
NM_004393DAG11
NM_015345DAAM21
NM_012081ELL21
NM_004426PHC11
NM_052906LRRC621
NM_033309MGC46551
NM_001009993LOC1300741
XM_936706KLHL171
NM_198317KLHL171
NM_145659IL271
NM_003461ZYX1
NM_001010972ZYX1
NM_001039213CEACAM161
NM_003021SGTA1
NM_194255SLC19A11
NM_001040202PAQR31
NM_001083926ASRGL11
NM_025080ASRGL11
NM_144997FLCN1
NM_015531DKFZP586P01231
NM_018189DPPA41
XM_939505LOC2855561
NM_007043KRR11
NM_0245621
NM_144963FAM91A11
NM_017893SEMA4G1
NM_002662PLD11
NM_022340ZFYVE201
NM_012087GTF3C51
NM_016540GPR831
NM_0155661
NM_002832PTPN71
NM_080588PTPN71
NM_015577RAI141
NM_012106ARL2BP1
XM_936101LOC6420311
NM_173491LSM111
NM_015253WSCD11
NM_207380FLJ433391
NM_004230EDG51
NM_018444PPM2C1
NM_014725STARD81
NM_002308LGALS91
NM_009587LGALS91
NM_001040078LOC6543461
NM_198086JUB1
NM_032876JUB1
NM_022745ATPAF11
NM_001042546ATPAF11
NM_004187JARID1C1
XM_940903ZC3H51
NM_001080419UNK1
NM_017837PIGV1
NM_003779B4GALT31
NM_000525KCNJ111
NM_004635MAPKAPK31
NM_007212RNF21
NM_007175ERLIN21
NM_198149TMEM581
NM_003612SEMA7A1
NM_199175C21orf1231
NM_0152411
XM_001128811LOC7312101
NM_017719SNRK1
NM_0011005941
NM_001083621ZBTB401
NM_014870ZBTB401
XM_943193LOC4000271
XM_931434LOC4000271
NM_001080395AATK1
NM_004391CYP8B11
NM_013989DIO21
NM_001007023DIO21
NM_000793DIO21
NM_004529MLLT31
NM_198494ZNF6421
NM_032169ACAD111
NM_015094HIC21
NM_031461CRISPLD11
NM_000868HTR2C1
NM_012164FBXW21
NM_024782NHEJ11
NM_004087DLG11
NM_0010984241
XM_934166LOC6534411
NM_015344LEPROTL11
NM_018361AGPAT51
NM_030964SPRY41
NM_152624DCP21
NM_004348RUNX21
NM_001015051RUNX21
NM_001024630RUNX21
NM_005715UST1
NM_001011703FAM125B1
NM_003087SNCG1
XM_039733KIAA09531
XM_940464KIAA09531
NM_024953C12orf301
NM_030953TIGD61
NM_005926MFAP11
NM_018622PARL1
NM_001037639PARL1
NM_181335ARHGAP81
NM_181334LOC5531581
NM_001017526ARHGAP81
NM_001003698RREB11
NM_001003699RREB11
NM_002955RREB11
NM_031433MFRP1
NM_006048UBE4B1
NM_0011055621
NM_005076CNTN21
NM_017759FLJ203091
NM_175921LOC2856361
NM_003918GYG21
NM_001079855GYG21
NM_181809BMP8A1
NM_002990CCL221
NM_0011024061
NM_025144ALPK11
NM_177968PPM1B1
NM_002357MXD11
NM_015430DKFZP586H21231
NM_001001991DKFZP586H21231
NM_004741NOLC11
NM_001904CTNNB11
NM_0010982091
NM_001080497MEGF91
XM_936860MEGF91
NM_004923MTL51
NM_014506TOR1B1
NM_014056HIGD1A1
NM_0010996681
NM_0010996691
NM_002148HOXD101
NM_002274KRT131
NM_014646LPIN21
NM_172229KREMEN21
NM_024507KREMEN21
XM_001129642TXNRD31
XM_001130163TXNRD31
NM_002997SDC11
NM_001006946SDC11
NM_207362MGC423671
NM_014381MLH31
NM_001040108MLH31
NM_021954GJA31
NM_146388MRPL41
NM_001017395TMCC11
NM_015008TMCC11
NM_001039350DPP61
NM_001936DPP61
NM_130797DPP61
NM_004277SLC25A271
NM_145044ZNF5011
NM_006092NOD11
NM_000383AIRE1
XM_498841LOC4407481
NM_173511ALS2CR131
NM_144599NIPA11
NM_003045SLC7A11
NM_006861RAB351
NM_006763BTG21
NM_033083EAF11
NM_153712TTL1
XM_001130539LOC7295351
XM_001129879LOC7314991
NM_058190C21orf701
XM_001131264LOC7297741
NM_133443GPT21
NM_134433RFX21
NM_000635RFX21
NM_024663NPEPL11
NM_033130SIGLEC101
NM_152363ANKRD411
NM_004756NUMBL1
NM_006037HDAC41
NM_033315RASL10B1
NM_013286RBM15B1
NM_019607C8orf441
NM_003885CDK5R11
NM_017919STX171
NM_1736011
NM_0010996501
NM_017563IL17RD1
NM_001080973IL17RD1
NM_001338CXADR1
NM_181706DPH41
NM_147198WFDC91
NM_001008738FNIP11
NM_133372FNIP11
NM_198152UTS2D1
NM_003438ZNF1371
NM_015419MXRA51
NM_005817M6PRBP11
NM_001095ACCN21
NM_020039ACCN21
NM_000990RPL27A1
NM_001955EDN11
NM_004827ABCG21
NM_015161ARL6IP11
NM_139235NOL61
NM_022917NOL61
NM_207459FLJ357671
NM_025191EDEM31
NM_000864HTR1D1
NM_152735ZBTB91
NM_012207HNRPH31
NM_021644HNRPH31
NM_000148FUT11
NM_003982SLC7A71
NM_012193FZD41
NM_022130GOLPH31
NM_001081002C14orf166B1
NM_173829P18SRP1
NM_021190PTBP21
NM_000860HPGD1
NM_001969EIF51
NM_183004EIF51
NM_0010808241
NM_005238ETS11
NM_032228MLSTD21
XM_496826NHSL11
XM_941807NHSL11
NM_138738FCRL21
NM_030764FCRL21
NM_001024647RAB3IP1
NM_022456RAB3IP1
NM_175624RAB3IP1
NM_175625RAB3IP1
NM_175623RAB3IP1
NM_024676C1orf1131
NM_182649PCNA1
NM_002592PCNA1
NM_198389PDPN1
NM_006474PDPN1
NM_001006624PDPN1
NM_001006625PDPN1
NM_032199ARID5B1
NM_000813GABRB21
NM_021911GABRB21
NM_014810CEP3501
NM_002547OPHN11
NM_020873LRRN11
NM_000129F13A11
NM_005593MYF51
NM_001431EPB41L21
NM_0011025591
XM_001130187LOC7290121
XM_001131195LOC7315891
NM_0011005951
NM_182620FAM33A1
NM_018246CCDC251
NM_004701CCNB21
NM_032105PPP1R12B1
NM_002481PPP1R12B1
NM_0010986241
NM_033290MID11
NM_000381MID11
NM_014464TINAG1
NM_003189TAL11
XM_936868C10orf1361
XM_926383C10orf1361
NM_173602DIP2B1
NM_138288C14orf1471
NM_015691WWC31
NM_021148ZNF2731
NM_020951ZNF5291
NM_005477HCN41
NM_0010122411
XM_001126700LOC7281471
XM_001126645LOC7306381
NM_014033METTL7A1
NM_130446KLHL61
NM_004399DDX111
NM_030653DDX111
NM_152438DDX111
NM_0142471
NM_000292PHKA21
XM_378661C17orf511
XM_944416C17orf511
NM_005822DSCR1L11
NM_017551GRID11
NM_015431TRIM581
NM_152742GPC21
NM_014096SLC43A31
NM_199329SLC43A31
NM_017611SLC43A31
NM_004728DDX211
NM_145008YPEL41
NM_015393DKFZP564O08231
NM_014571HEYL1
NM_025154UNC84A1
NM_170776GPR971
NM_033257DGCR6L1
NM_005675DGCR61
NM_001007231ARHGAP251
NM_014882ARHGAP251
NM_017575SMG61
NM_183230IKZF31
NM_183229IKZF31
NM_183231IKZF31
NM_183228IKZF31
NM_183232IKZF31
NM_012481IKZF31
NM_001012418LOC3401561
NM_144582TEX2611
XM_933701LOC6441651
NM_021574BCR1
NM_004327BCR1
XM_001129467LOC7284681
NM_005512LRRC321
NM_024933ANKRD531
NM_015251ASCIZ1
NM_001044369C18orf511
NM_144613COX6B21
NM_006634VAMP51
NM_006268DPF21
NM_207405FLJ464811
NM_001012515FECH1
NM_000140FECH1
NM_003342UBE2G11
NM_017594DIRAS21
NM_018389SLC35C11
NM_017908ZNF4461
NM_015554GLCE1
NM_001010984C1orf1241
NM_018228C14orf1151
NM_014830ZBTB391
NM_006464TGOLN21
NM_0010986721
NM_002079GOT11
NM_020804PACSIN11
NM_178129P2RY81
NM_053005HCCA21
NM_138572TBN1
NM_001780CD631
NM_001040034CD631
NM_0010986121
NM_001079843CASZ11
NM_000278PAX21
NM_003989PAX21
NM_003990PAX21
NM_003987PAX21
NM_003988PAX21
NM_213600PLA2G4F1
NM_170731BDNF1
NM_001709BDNF1
NM_170732BDNF1
NM_170733BDNF1
NM_170734BDNF1
NM_170735BDNF1
NM_018179ATF7IP1
NM_000831GRIK31
NM_017742ZCCHC21
NM_017681NUP62CL1
NM_005814GPA331
NM_005472KCNE31
NM_033387FAM78A1
NM_002167ID31
NM_019854PRMT81
NM_022462HIF3A1
NM_152794HIF3A1
NM_152795HIF3A1
NM_003212TDGF11
NM_182515ZNF7141
NM_002196INSM11
NM_018312SAPS31
NM_005885MARCH61
NM_003322TULP11
NM_006482DYRK21
NM_003583DYRK21
NM_152271LONRF11
NM_013265C11orf21
NM_006691XLKD11
XM_938688LOC6496181
NM_004513IL161
NM_172217IL161
NM_015375RIPK51
NM_199462RIPK51
NM_004059CCBL11
NM_057178RFFL1
NM_001017368RFFL1
NM_000533PLP11
NM_199478PLP11
NM_033631LUZP11
NM_001079846CREBBP1
NM_004380CREBBP1
NM_001458FLNC1
NM_031464RPS6KL11
NM_012072CD931
NM_033551LARP11
NM_015315LARP11
NM_144777SCEL1
NM_003843SCEL1
NM_001013622FAM53A1
NM_000742CHRNA21
NM_000115EDNRB1
NM_032436C13orf81
NM_015064ERC11
NM_178039ERC11
NM_178040ERC11
NM_178038ERC11
NM_178037ERC11
NM_001081686G6PC21
NM_021176G6PC21
NM_002479MYOG1
NM_006413RPP301
NM_002076GNS1
NM_000428LTBP21
NM_001759CCND21
NM_001008709PPP1CA1
NM_206873PPP1CA1
NM_002708PPP1CA1
NM_152673MUC201
NM_0010985161
NM_000599IGFBP51
NM_007218RNF1391
NM_181710ZNRF41
XM_001126375LOC7279221
XM_001126361LOC7279221
XM_001126406LOC7279221
XM_001126391LOC7279221
XM_001126417LOC7279221
NM_006625FUSIP11
NM_020630RET1
NM_018293ZNF6541
XM_001126706ZNF6541
NM_024689CXorf361
NM_014615KIAA01821
NM_004795KL1
NM_176816CCDC1251
NM_199169TMEPAI1
NM_199170TMEPAI1
NM_199171TMEPAI1
NM_020182TMEPAI1
NM_003575ZNF2821
NM_001042552TATDN31
NM_001042553TATDN31
NM_001047SRD5A11
NM_022080NAPB1
XM_001132119LOC2574071
XM_001129456LOC2574071
NM_005985SNAI11
NM_001003674C18orf11
NM_181483C18orf11
NM_181481C18orf11
NM_001003675C18orf11
NM_004338C18orf11
NM_181482C18orf11
XM_938665USP6NL1
NM_001080491USP6NL1
XM_927409USP6NL1
XM_943800USP6NL1
NM_015049TRAK21
NM_0010136621
NM_007166PICALM1
NM_001008660PICALM1
NM_0010988131
NM_0151461
NM_0010988121
NM_020773TBC1D141
NM_024917CXorf341
NM_001034852SMOC11
NM_022137SMOC11
NM_001077484SLC38A11
NM_030674SLC38A11
NM_003904ZNF2591
NM_014502PRPF191
NM_003644GAS71
NM_201432GAS71
NM_201433GAS71
NM_145273CD300LG1
NM_004921CLCA31
XM_940362LOC6459841
XM_928946LOC6459841
NM_152910DGKH1
NM_178009DGKH1
NM_001004304ZNF7401
NM_014906PPM1E1
NM_052864TIFA1
NM_001037164ARL4A1
NM_005738ARL4A1
NM_212460ARL4A1
XM_001133630LOC6506521
XM_001133005LOC6448601
NM_001029875RGS7BP1
NM_007220CA5B1
NM_033259CAMK2N21
NM_024071ZFYVE211
NM_024816RABEP21
NM_133266SHANK21
NM_001005473PLCXD31
NM_014938MLXIP1
NM_001006641SLC25A251
NM_001006642SLC25A251
NM_052901SLC25A251
NM_001006643SLC25A251
XM_001129328LOC7284181
XM_001126768LOC7279831
XM_929034LOC6460741
NM_019008SMCR7L1
NM_001077196PDE11A1
NM_001077197PDE11A1
NM_016953PDE11A1
XM_942072CPN21
NM_001080513CPN21
NM_207577MAP61
NM_015197PACS21
NM_0011009131
NM_015686TMEM281
NM_080668CDCA51
NM_005957MTHFR1
NM_003861WDR221
NM_0011004171
NM_175748C14orf1301
NM_003943GENX-34141
NM_018710TMEM55A1
NM_013260SAP30BP1
NM_017723C9orf1671
NM_0010853771
NM_002387MCC1
NM_001003937TSPYL61
NM_002340LSS1
NM_203405KRTAP26-11
NM_030805LMAN2L1
NM_000567CRP1
NM_017991FLJ100811
NM_025236RNF391
NM_170769RNF391
NM_003748ALDH4A11
NM_004475FLOT21
NM_032294CAMKK11
NM_172206CAMKK11
NM_000911OPRD11
NM_000960PTGIR1
NM_004924ACTN41
NM_005543INSL31
NM_031890CECR61
NM_001012958DISC11
NM_000785CYP27B11
NM_199229RPE1
NM_006916RPE1
NM_020796SEMA6A1
NM_177972TUB1
NM_003320TUB1
XM_001134215PDPR1
NM_017990PDPR1
NM_014155ZBTB441
NM_078474TM2D31
NM_025141TM2D31
NM_175862CD861
NM_006889CD861
NM_020845PITPNM21
NM_002149HPCAL11
NM_134421HPCAL11
NM_177457LYNX11
NM_177477LYNX11
NM_177476LYNX11
NM_178013PRIMA11
NM_002015FOXO1A1
NM_173477USH1G1
NM_003146SSRP11
NM_014773KIAA01411
NM_003347UBE2L31
NM_198157UBE2L31
NM_016173HEMK11
XM_001133760ZNF5191
NM_021135RPS6KA21
NM_001006932RPS6KA21
NM_005011NRF11
NM_001040110NRF11
NM_017712PGPEP11
NM_014945ABLIM31
NM_002751MAPK111
NM_004067CHN21
NM_001039936CHN21
NM_0011008291
NM_001031698PRPF40B1
NM_012272PRPF40B1
NM_001012508SPRN1
NM_001039355SLC25A291
NM_145055C18orf251
NM_001008239C18orf251
NM_000950PRRG11
NM_145298APOBEC3F1
NM_145074HTRA21
NM_013247HTRA21
NM_021916ZNF701
NM_194434VAPA1
NM_003574VAPA1
NM_078470COX151
NM_004376COX151
NM_004560ROR21
NM_018018SLC38A41
NM_032932RAB11FIP41
NM_144570HN1L1
NM_148957TNFRSF191
NM_018644B3GAT11
NM_054025B3GAT11
NM_213589RAPH11
NM_0011111131
NM_005339HIP21
NM_0011111121
NM_005336HDLBP1
NM_203346HDLBP1
NM_139276STAT31
NM_003150STAT31
NM_213662STAT31
NM_001040146CTF81
NM_001039690CTF81
NM_001040144CTF81
NM_080625C20orf1601
NM_173073SLC35C21
NM_173179SLC35C21
NM_015945SLC35C21
NM_004148NINJ11
XM_495908DDX121
NM_001748CAPN21
NM_0010992711
NM_152408C5orf371
NM_022166XYLT11
XM_001125986LOC2838241
NM_018463ITFG21
NM_021033RAP2A1
NM_001128AP1G11
NM_001030007AP1G11
NM_001076778FAM107A1
NM_007177FAM107A1
NM_003787NOL41
NM_005857ZMPSTE241
NM_012316KPNA61
NM_032826SLC35B41
NM_0178921
NM_017671C20orf421
NM_0330261
NM_006952UPK1B1
NM_199138FAM123A1
NM_152704FAM123A1
NM_014947FOXJ31
NM_001031679MSRB31
NM_198080MSRB31
NM_000865HTR1E1
NM_198449EMB1
NM_003356UCP31
NM_022106C20orf1771
NM_183337RGS111
NM_003834RGS111
NM_024944CHODL1
NM_017996DET11
NM_033505SELI1
NM_005994TBX21
NM_001008215MGC521101
NM_001014435CA71
NM_005182CA71
NM_016169SUFU1
NM_001008693CST91
NM_014413EIF2AK11
NM_181458PAX31
NM_181461PAX31
NM_015557CHD51
NM_005416SPRR31
NM_0010975891
NM_015321CRTC11
NM_0010984821
NM_007067MYST21
NM_018201TBC1D131
NM_181846ZSCAN221
NM_000276OCRL1
NM_001587OCRL1
NM_001005845ADAM91
NM_001025109CD341
NM_001773CD341
NM_015347RIMBP21
XM_934514LOC6447141
XM_945782LOC6447141
XM_001132091LOC7312081
XM_001125918LOC7278721
NM_013309SLC30A41
NM_017924C14orf1191
XM_942121LOC6458431
XM_930419LOC6458431
XM_001132080LOC7310071
XM_928632LOC6456191
NM_203464AK3L11
NM_013410AK3L11
NM_001005353AK3L11
NM_006343MERTK1
NM_001081491NXF11
NM_144991C21orf291
NM_001241CCNT21
NM_058241CCNT21
NM_018639WSB21
NM_152275TTC30A1
NM_001286CLCN61
XM_933796SLC45A41
NM_001002909GPATCH81
NM_006999POLS1
NM_020980AQP91
NM_003901SGPL11
NM_001080975REPS21
NM_004726REPS21
NM_004622TSN1
NM_018013SOBP1
NM_004296RGS61
NM_152499CCDC241
NM_022755IPPK1
NM_006191PA2G41
NM_032272MAF11
NM_012218ILF31
NM_001003694BRPF11
NM_004634BRPF11
NM_001011668CHCHD71
NM_024300CHCHD71
NM_001011671CHCHD71
NM_001011667CHCHD71
NM_001011670CHCHD71
NM_001011669CHCHD71
NM_173627FLJ352201
NM_001002762DNAJB121
NM_017626DNAJB121
XM_938519DKFZP434I07141
XM_929673DKFZP434I07141
NM_012250RRAS21
NM_0011026691
NM_182493MLCK1
NM_173656ZNF6191
NM_000321RB11
NM_020310MNT1
NM_198581ZC3H61
NM_015261NCAPD31
NM_015932POMP1
NM_032567SPZ11
NM_004660DDX3Y1
NM_001009899KIAA20181
NM_182764ELMO21
NM_133171ELMO21
NM_012338TSPAN121
NM_007038ADAMTS51
NM_147156SGMS11
NM_001966EHHADH1
NM_032449CC2D1B1
NM_018184ARL8B1
NM_024817THSD41
NM_021936PAPPA21
NM_031905ARMC101
XM_371655LOC3891371
NM_002381MATN31
NM_138809CMBL1
NM_014309RBM91
NM_001082576RBM91
NM_001082577RBM91
NM_001031695RBM91
NM_001082578RBM91
NM_001082579RBM91
NM_020179C11orf751
NM_033481FBXO91
NM_033480FBXO91
NM_012347FBXO91
NM_147187TNFRSF10B1
NM_003842TNFRSF10B1
NM_152280SYT111
NM_001080485ZNF2751
NM_014730KIAA01521
XM_941380UNC13C1
NM_001080534UNC13C1
NM_001004342TRIM671
NM_016239MYO15A1
NM_003681PDXK1
NM_022893BCL11A1
NM_006918SC5DL1
NM_001024956SC5DL1
NM_004808NMT21
NM_052905FMNL21
NM_001148ANK21
NM_020977ANK21
NM_018409LRP2BP1
NM_023076C16orf281
NM_015529MOXD11
NM_014613UBXD81
NM_003027SH3GL31
NM_014630ZNF5921
NM_032352BRMS1L1
NM_016021UBE2J11
NM_003200TCF31
NM_005270GLI21
NM_020792AADACL11
NM_001007229SPOP1
NM_001007230SPOP1
NM_001007226SPOP1
NM_003563SPOP1
NM_001007228SPOP1
NM_001007227SPOP1
NM_019096GTPBP21
NM_005759ABI21
XM_001126750ABI21
NM_004326BCL91
NM_000407GP1BB1

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317