Predicted Off-targets for siRNA "aggcaagcuguccuucuuuga" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

23 hits were found for GCAAGCUGUCCUUCUUUGA (10 guide strand hits and 13 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_001379 DNMT1 1388 1406 agAAGCUGUCCaUCUUUGA52 3 9   false   <90%   5434
NM_002661 PLCG2 1654 1672 cCAAGCUGUCCUUCagUGA47 3 13 c false   <90%   4263
NR_003133 LOC400759 15135 15153 caAAGCUGUCCgUCUUUGc47 4 9   false   <90%   16075
NM_001005281 OR6B1 191 209 cCAAcCUGUCCUUCUUgGA23 3 11 c false   <90%   936
NM_001004463 OR10G7 185 203 cCAAcCUGUCCUUCaUUGA21 3 9 c false   <90%   936
NM_001001953 OR10G9 185 203 cCAAcCUGUCCUUCaUUGA21 3 9 c false   <90%   936
NM_001004462 OR10G4 185 203 cCAAcCUGUCCUUCaUUGA21 3 9 c false   <90%   936
NM_130445 COL18A1 1440 1458 aCAAGCUGaCCUUCaUUGA13 3 7 c false   <90%   5398
NM_030582 COL18A1 1952 1970 aCAAGCUGaCCUUCaUUGA13 3 7 c false   <90%   5910
NM_002182 IL1RAP 1510 1528 aCAAGCUGUgCaUCUUUGA-18 3 8   false   <90%   4726


Hits to Sense strand














AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_053028 MYLK 797 815 UCAAAGAAGGACAGaUgGg46 3 14 c false   <90%   7492
NM_053026 MYLK 797 815 UCAAAGAAGGACAGaUgGg46 3 14 c false   <90%   7645
NM_053027 MYLK 797 815 UCAAAGAAGGACAGaUgGg46 3 14 c false   <90%   7699
NM_053025 MYLK 797 815 UCAAAGAAGGACAGaUgGg46 3 14 c false   <90%   7852
NM_015381 FAM19A5 259 277 UCAAAGAAGGuCAGCUgGC15 2 10 c false   <90%   2652
NM_173598 KSR2 6412 6430 cggAAGAAGGcCAGCUUGC5 4 8 c false   <90%   16655
NM_006269 RP1 2206 2224 aucAAGAuGGACAGCUUGC4 4 11 bc false   <90%   7100
NM_024704 C20orf23 3013 3031 aaAAAGAAGaACAGCUUGC3 3 9 bc false   <90%   5274
NM_080830 CST11 167 185 UaugcGAAGGACAGCUUGC-19 4 14 bc false   <90%   448
NM_130794 CST11 167 185 UaugcGAAGGACAGCUUGC-19 4 14 bc false   <90%   553
XM_944654 LOC648716 1573 1591 aCAAAGAAaGgCAGCUUGC-23 3 8 c false   <90%   2230
XM_935966 LOC641798 1573 1591 aCAAAGAAaGgCAGCUUGC-23 3 8 c false   <90%   2230
XM_935369 LOC646329 1573 1591 aCAAAGAAaGgCAGCUUGC-23 3 8 c false   <90%   2230


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1587
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_007220CA5B3
NM_016544RBJ3
NM_203329CD593
NM_203331CD593
NM_203330CD593
NM_000611CD593
NM_024817THSD42
NM_001013659ZNF7932
NM_032303HSDL22
NM_001012393OPCML2
NM_002545OPCML2
NM_002429MMP192
NM_052966FAM129A2
NM_005670EPM2A2
NM_152673MUC202
NM_0010985162
NM_015879ST8SIA32
NM_153686LCORL2
NM_0010992942
XM_936510KIAA16442
NM_022166XYLT12
XM_001125986LOC2838242
NM_014877HELZ2
NM_000542SFTPB2
NM_001776ENTPD12
NM_0010981752
NM_139279MCFD22
NM_145053UBQLNL2
NM_014772KIAA04272
NM_0010987872
NM_016526BET1L2
NM_017699SIDT12
NM_130830LRRC152
NM_000868HTR2C2
NM_014396VPS412
NM_080631VPS412
NM_014869IQSEC12
NM_019034RHOF2
NM_182515ZNF7142
NM_144578C14orf322
NM_020705TBC1D242
NM_005895GOLGA32
NM_0207212
NM_001003652SMAD22
NM_005901SMAD22
NM_003382VIPR22
NM_006774INMT2
NM_021064HIST1H2AG2
NM_182644EPHA32
NM_001080435WHDC12
XM_939866WHDC12
NM_152263TPM32
NM_003387WIPF12
NM_001077269WIPF12
NM_032189ATP11A2
NM_015205ATP11A2
NM_015090NFASC2
NM_032521PARD6B2
NM_004928C21orf22
NM_183413FBXO442
NM_033182FBXO442
NM_001014765FBXO442
NM_183412FBXO442
NM_031448C19orf122
NM_001031726C19orf122
NM_001570IRAK22
NM_198098AQP12
XM_929714LOC6467622
XM_935722LOC6467622
XM_938418LOC6467622
NM_006268DPF22
NM_003644GAS72
NM_201432GAS72
NM_201433GAS72
NM_0011031472
NM_0011031482
NM_0011031462
NM_015575TNRC152
NM_022758C6orf1062
NM_024294C6orf1062
NM_018688BIN32
NM_002957RXRA2
NM_022048CSNK1G12
NM_004227PSCD32
NM_021007SCN2A2
NM_001040142SCN2A2
NM_001040143SCN2A2
XM_001132013ANKH2
NM_054027ANKH2
NM_003161RPS6KB12
NM_012174FBXW82
NM_153348FBXW82
NM_198868TBC1D9B2
NM_015043TBC1D9B2
NM_003681PDXK2
NM_014661FAM53B2
NM_015042ZNF6092
NM_178169RASSF32
NM_004571PKNOX12
NM_0011001642
NM_0011001662
NM_014721PHACTR22
NM_0011001652
NM_000809GABRA42
NM_203447DOCK81
NM_002134HMOX21
NM_005725TSPAN21
NM_052918SORCS11
NM_001013031SORCS11
XM_001130839NR1D21
NM_152665TCTEX1D11
NM_018000MREG1
NM_015012TMEM41B1
NM_152380TBX151
NM_004171SLC1A21
NM_001001702FLJ333601
NM_004522KIF5C1
NM_172097CATSPER21
NM_016453NCKIPSD1
NM_184231NCKIPSD1
NM_012081ELL21
NM_024636STEAP41
XM_941142FTO1
NM_001080432FTO1
XM_941380UNC13C1
NM_001080534UNC13C1
NM_022336EDAR1
NM_014904RAB11FIP21
NM_198849LOC2835141
NM_004098EMX21
NM_024096XTP3TPA1
NM_006489NOVA11
NM_002515NOVA11
XM_939750USP321
NM_032582USP321
NM_019069WDR5B1
NM_012338TSPAN121
NM_019607C8orf441
NM_004087DLG11
NM_0010984241
NM_005962MXI11
NM_001008541MXI11
NM_130439MXI11
NM_016376ANKFY11
NM_145698ACBD51
NM_001042473ACBD51
NM_004453ETFDH1
NM_007174CIT1
NM_023107FGFR11
NM_023108FGFR11
NM_000139MS4A21
NM_032433ZNF3331
NM_016023OTUD6B1
NM_145011ZNF251
NM_015225KIAA03671
NM_018211RAVER21
NM_020813ZNF4711
NM_017694FLJ201601
NM_001012729DUXA1
XM_943454LOC6465881
XM_933738LOC6465881
XM_935989LOC6465881
NM_005442EOMES1
NM_001130AES1
NM_198970AES1
NM_198969AES1
XM_943640FLJ322551
NM_022893BCL11A1
NM_022129PBLD1
NM_207497FLJ437521
NM_006572GNA131
NM_013347RPA41
NM_006252PRKAA21
XM_001133377LOC7324151
NM_000212ITGB31
NM_016132MYEF21
NM_005840SPRY31
NM_178566ZDHHC211
NM_003948CDKL21
NM_000245MET1
NM_024702ZNF7501
NM_024770METTL81
NM_023068SIGLEC11
NM_031911C1QTNF71
NM_001353AKR1C11
NM_024764C14orf1611
NM_052862RCSD11
NM_018407LAPTM4B1
NM_004391CYP8B11
NM_001077693ECSM21
NM_080671KCNE41
NM_004170SLC1A11
NM_001039479KIAA03171
NM_213607CCDC1031
NM_022776OSBPL111
NM_139177SLC39A111
NM_001387DPYSL31
NM_015294TRIM371
NM_003724JRK1
NM_007255B4GALT71
NM_015374UNC84B1
NM_005964MYH101
NM_016598ZDHHC31
NM_005495SLC17A41
NM_014438IL1F81
NM_015564LRRTM21
NM_0010992781
NM_152288TMEM142C1
NM_020124IFNK1
NM_052880PIK3IP11
NM_006814PSMF11
NM_178578PSMF11
XM_036729USP411
XM_001128849LOC7312181
XM_001126434LOC7280511
NM_031244SIRT51
NM_194252TTLL111
NM_016169SUFU1
NM_001826CKS1B1
NM_003696OR6A21
NM_004237TRIP131
NM_020150SAR1A1
NM_000623BDKRB21
NM_001981EPS151
NM_032484GHDC1
NM_032765TRIM521
NM_025054VCPIP11
NM_033035TSLP1
NM_138551TSLP1
XM_001133837LOC7320991
XM_001133987LOC7296811
XM_001132516LOC7290491
NM_0011045581
NM_024930ELOVL71
NM_016076C1orf1211
NM_014310RASD21
NM_001029883FLJ349311
NM_001040107HVCN11
NM_032369HVCN11
NM_175078KRT771
NM_002677PMP21
NM_001040202PAQR31
NM_138450ARL111
NM_002632PGF1
NM_015101GLT25D21
NM_018222PARVA1
NM_014840NUAK11
NM_057178RFFL1
NM_001017368RFFL1
NM_152503C20orf1321
NM_001752CAT1
NM_139316AMPH1
NM_001635AMPH1
NM_015058KIAA05641
NM_138635H2AFV1
NM_030934C1orf251
NM_0010985001
NM_019590KIAA12171
NM_0010985011
NM_000333ATXN71
NM_183238ZNF6051
NM_014787DNAJC61
NM_012091ADAT11
NM_014299BRD41
NM_032980DTNA1
NM_001390DTNA1
NM_032975DTNA1
NM_015155LARP51
NM_015888HOOK11
NM_001077484SLC38A11
NM_030674SLC38A11
NM_152666PLD51
NM_003134SRP141
NM_003319TTN1
NM_133437TTN1
NM_133378TTN1
NM_133432TTN1
NM_018584CAMK2N11
NM_001043229LOC7510711
NM_032431SYVN11
NM_172230SYVN11
XM_930713LOC6423401
XM_943538LOC6423401
NM_002847PTPRN21
NM_130843PTPRN21
NM_130842PTPRN21
NM_003713PPAP2B1
NM_177414PPAP2B1
NM_153447NLRP51
NM_003412ZIC11
NM_182916TRNT11
XM_001128449LOC7281971
NM_198264C1orf21
NM_006589C1orf21
NM_020778ALPK31
NM_006158NEFL1
NM_020699GATAD2B1
NM_032440LCOR1
NM_057749CCNE21
NM_207015NAALADL21
NM_020403PCDH91
NM_203487PCDH91
NM_006122MAN2A21
NM_005786TSHZ11
NM_020947KIAA16091
XM_001126898LOC7282211
NM_033666ITGB11
NM_032961PCDH101
NM_001006657WDR351
NM_020779WDR351
NM_002227JAK11
XM_001125855MBOAT41
XM_940502MBOAT41
NM_019072SGTB1
NM_002271RANBP51
NM_014005PCDHA91
NM_080797DIDO11
NM_183075CYP2U11
XM_001127284CXorf311
XM_001127244CXorf311
NM_015316PPP1R13B1
NM_000147FUCA11
NM_003355UCP21
NM_178498SLC5A121
NM_002025AFF21
NM_017750RETSAT1
XM_001127274SMYD21
NM_002262KLRD11
NM_007334KLRD11
NM_014810CEP3501
NM_032368LZIC1
NM_001649SHROOM21
NM_005898CAPRIN11
NM_018246CCDC251
NM_001005337PKP11
NM_000299PKP11
NM_006097MYL91
NM_181526MYL91
NM_015340LARS21
NM_152267RNF1851
NM_002189IL15RA1
NM_172200IL15RA1
NM_023007JMJD41
NM_014744TBC1D51
NM_015092SMG11
NM_001029874REP151
NM_001012418LOC3401561
XM_932026LOC6441731
XM_942992LOC6441731
NM_139057ADAMTS171
NM_005215DCC1
NM_002942ROBO21
NM_000240MAOA1
NM_003128SPTBN11
XM_001130020KIAA11471
XM_001130081KIAA11471
NM_001080392KIAA11471
NM_001042601TTC141
NM_018367PHCA1
NM_001013655LOC3898341
NM_024784ZBTB31
XM_001131501FLJ902311
NM_001080407GLB1L31
NM_030813CLPB1
NM_003162STRN1
NM_017515SLC35F21
NM_017728TMEM1041
NM_024971TRPM31
NM_001007471TRPM31
NM_206947TRPM31
NM_206946TRPM31
NM_206944TRPM31
NM_206945TRPM31
NM_020952TRPM31
NM_001040197AGTRAP1
NM_001040195AGTRAP1
NM_001040194AGTRAP1
NM_020350AGTRAP1
NM_001040196AGTRAP1
NM_138370LOC914611
XM_001129019SAPS21
NM_014678SAPS21
NM_0011055411
NM_005382NEFM1
NM_032572RNASE71
NM_001094ACCN11
NM_183377ACCN11
NM_003407ZFP361
NM_004748CCPG11
NM_020739CCPG11
NM_003799RNMT1
NM_018988GFOD11
NM_014723SNPH1
NM_012193FZD41
NM_014580SLC2A81
NM_017988SCYL21
NM_017758ALKBH51
NM_003253TIAM11
NM_001003811TEX111
NM_031276TEX111
NM_182612PDDC11
NM_001081573GAB31
NM_080612GAB31
NM_194452RNF1211
NM_194453RNF1211
NM_018320RNF1211
XM_001126151LOC7278581
XM_001130844LOC7287641
NM_138923TAF11
NM_004606TAF11
NM_0010997331
NM_001117ADCYAP11
NM_032982CASP21
NM_032983CASP21
XM_932931LOC6454851
XM_944437LOC6454851
NM_032869NUDCD11
NM_205848SYT61
NM_014999RAB211
NM_006425SLU71
NM_001009899KIAA20181
NM_0150381
NM_006918SC5DL1
NM_001024956SC5DL1
NM_017563IL17RD1
NM_001080973IL17RD1
NM_178135HSD17B131
NM_001040441ZBTB81
XM_001124597LOC7304111
NM_152654DAND51
NM_001010922C1orf1781
NM_004857AKAP51
NM_020682AS3MT1
NM_017853TXNL4B1
NM_207404ZNF6621
NM_153255MCM91
NM_0010854001
XM_001134215PDPR1
NM_017990PDPR1
NM_014783ARHGAP11A1
NM_198484ZNF6211
NM_0010984141
NM_020745AARS21
NM_153256C10orf471
NM_198560LHFPL41
NM_003042SLC6A11
NM_018411HR1
NM_005144HR1
NM_001077401ACVRL11
NM_000020ACVRL11
NM_003840TNFRSF10D1
NM_003856IL1RL11
NM_130848C5orf201
NM_0133181
NM_000356TCOF11
NM_001008656TCOF11
NM_006166NFYB1
NM_145055C18orf251
NM_001008239C18orf251
NM_012288TRAM21
NM_001183ATP6AP11
NM_001011547SLC5A91
NM_001032391LCMT11
NM_016309LCMT11
NM_004185WNT2B1
NM_024494WNT2B1
NM_138368DKFZp761E1981
NM_182558C12orf361
NM_004814WDR571
NM_0010996911
NM_003236TGFA1
NM_023079UBE2Z1
NM_018953HOXC51
XM_001125792LOC7278341
XM_926013LOC6423981
NM_001039577CCNL21
NM_005668ST8SIA41
NM_130807MOBKL2A1
NM_022444SLC13A11
NM_013359ZNF2211
NM_003423ZNF431
NM_152909ZNF5481
NM_020834HOMEZ1
NM_133480TADA3L1
NM_001037330TRIM16L1
NM_006470TRIM161
XM_941026ING51
XM_001126273LOC7277731
NM_032329ING51
NM_001080480MBOAT11
XM_001131050MBOAT11
XM_001131044MBOAT11
NM_001017396ZNF21
NM_021088ZNF21
NM_0011004231
NM_0011004221
NM_0011004241
NM_015535LOC260101
NM_207401FLJ457171
NM_004155SERPINB91
NM_198532C19orf351
NM_001037165FOXK11
NM_001042697ZSWIM71
NM_001042698ZSWIM71
NM_181877ZSCAN21
NM_001037582SCD51
NM_213598ZNF5431
NM_012099CD3EAP1
NM_173803MPV17L1
NM_001080125CASP81
NM_001080124CASP81
NM_033355CASP81
NM_001228CASP81
NM_033356CASP81
NM_138287DTX3L1
NM_006085BPNT11
NM_014668GREB11
NM_000651CR11
NM_000573CR11
NM_018477ACTR101
NM_031912SYT151
NM_000990RPL27A1
NM_032782HAVCR21
NM_001816CEACAM81
XM_379636C9orf1221
XM_940165C9orf1221
NM_153371LNX21
NM_003622PPFIBP11
NM_152701ABCA131
NM_020714ZNF4901
NM_022754SFXN11
NM_203307ZNF3211
NM_000254MTR1
NM_006413RPP301
NM_017666SUHW31
NM_004230EDG51
XM_001128169LOC7286871
XM_940089FLJ396391
XM_370932FLJ396391
NM_003190TAPBP1
NM_016037UTP11L1
NM_144974CCDC1221
NM_001089ABCA31
NM_024865NANOG1
NM_007146VEZF11
NM_020673RAB22A1
NM_001690ATP6V1A1
NM_198718PTGER31
NM_182552WDR271
NM_017649CNNM21
NM_199076CNNM21
NM_181876PPP2R2C1
NM_020416PPP2R2C1
XM_941162LOC4009501
XM_376049LOC4009501
NM_016217HECA1
NM_020850RANBP101
NM_013358PADI11
XM_945436LOC4009581
XM_379100LOC4009581
NM_021643TRIB21
NM_002558P2RX11
NM_018176LGI21
NM_021155CD2091
NM_002310LIFR1
NM_018389SLC35C11
NM_018509LRRC591
NM_001003407ABLIM11
NM_001003408ABLIM11
NM_002313ABLIM11
NM_006720ABLIM11
NM_002813PSMD91
NM_016605FAM53C1
NM_175062RASGEF1C1
NM_014448ARHGEF161
NM_001080414KIAA15091
XM_496003KIAA15091
XM_941642KIAA15091
NM_022819PLA2G2F1
NM_030798WBSCR161
NM_018013SOBP1
NM_030651PRRT11
NM_012239SIRT31
NM_001017524SIRT31
NM_020338ZMIZ11
NM_024735FBXO311
NM_032683FKSG241
NM_003702RGS201
NM_170587RGS201
NM_001106ACVR2B1
NM_207446LOC4004511
NM_022460HS1BP31
NM_005400PRKCE1
NM_152527SLC16A141
NM_032175UTP151
XM_936831IQSEC31
NM_000554CRX1
NM_031282FCRL41
NM_198465NRK1
NM_152519FLJ238611
NM_001276CHI3L11
NM_0011127171
NM_0011127201
NM_014988DKFZP686A012471
NM_0011127191
NM_0011127181
NM_0178921
NM_001012339DNAJA51
NM_194283DNAJA51
NM_194318B3GALTL1
NM_003486SLC7A51
NM_001655ARCN11
XM_001125708LOC7277801
XM_001133524LOC7316441
NM_183240TMEM371
NM_002299LCT1
NM_183048ZMYND81
NM_183047ZMYND81
NM_012408ZMYND81
NM_174902LDLRAD31
NM_004268CRSP61
NM_015191SNF1LK21
NM_001040000MLLT41
NM_000195HPS11
NM_015471NSL11
NM_001042549NSL11
NM_175854PAN31
NM_014262LEPREL21
NM_000795DRD21
NM_016574DRD21
NM_173812DPY19L21
NM_012400PLA2G2D1
NM_001029955WDR21B1
NM_001040273TYSND11
NM_033549TRIM411
NM_201627TRIM411
NM_178520TMEM1051
NM_014424HSPB71
NM_002930RIT21
NM_198688KRTAP10-61
NM_181688KRTAP10-101
NM_015627LDLRAP11
NM_018241TMEM341
NM_001044387ZNF5571
NM_024341ZNF5571
NM_001044388ZNF5571
NM_0011127361
NM_015224C3orf631
NM_005433YES11
NM_004577PSPH1
NM_016540GPR831
NM_183397PXMP41
NM_007238PXMP41
NM_177999ASB61
NM_017873ASB61
NM_014898ZFP301
NM_014746RNF1441
NM_198468C6orf1671
NM_001040665STEAP21
NM_152999STEAP21
NM_018138TBCCD11
NM_003693SCARF11
NM_145351SCARF11
NM_145350SCARF11
NM_145349SCARF11
NM_145352SCARF11
NM_181846ZSCAN221
NM_000148FUT11
XM_001128450LOC7282291
XM_928466LOC6454261
XM_001131298LOC7309901
XM_001128423LOC7282291
NM_006879MDM21
NM_006881MDM21
NM_002392MDM21
NM_006878MDM21
NM_006882MDM21
NM_017741C4orf301
NM_145343APOL11
NM_003661APOL11
NM_000961PTGIS1
NM_173672PPIL61
NM_0011112981
NM_181489ZNF4451
NM_021916ZNF701
NM_017520HSMPP81
NM_001024596ZNF7721
XM_929835LOC2840231
XM_941810LOC2840231
NM_017420SIX41
NM_145207SPATA51
NM_178172LOC3383281
NM_152608C1orf551
NM_021258IL22RA11
NM_003149STAC1
NM_014982PCNX1
NM_024909C6orf1341
NM_003359UGDH1
NM_005207CRKL1
NM_000806GABRA11
NM_007057ZWINT1
NM_032997ZWINT1
NM_001005413ZWINT1
NM_015492C15orf391
NM_002718PPP2R3A1
NM_181897PPP2R3A1
NM_144567ANGEL21
NM_006389HYOU11
NM_016065MRPS161
XM_209227LOC6534641
NM_145238ZSCAN201
NM_007275TUSC21
NM_014309RBM91
NM_001082576RBM91
NM_001082577RBM91
NM_001031695RBM91
NM_001082578RBM91
NM_001082579RBM91
NM_000192TBX51
NM_080717TBX51
NM_181486TBX51
NM_015904EIF5B1
NM_005500SAE11
NM_000629IFNAR11
NM_005769CHST41
NM_001848COL6A11
NM_001049SSTR11
NM_025135FHOD31
NM_014276RBPJL1
NM_078470COX151
NM_004867ITM2A1
NM_017542POGK1
NM_020240CDC42SE21
NM_001038702CDC42SE21
NM_145013C11orf451
NM_032330CAPNS21
NM_0010994361
NM_172056KCNH21
NM_033274ADAM191
NM_001338CXADR1
XM_933614LOC6464341
XM_929242LOC6463011
NM_015040PIP5K31
NM_004852ONECUT21
NM_012301MAGI21
NM_139283PPTC71
XM_941352LOC2552751
XM_171855LOC2552751
NM_005902SMAD31
NM_000104CYP1B11
NM_1827627A51
NM_003966SEMA5A1
NM_005596NFIB1
NM_001065TNFRSF1A1
NM_020956PRX1
NM_203290POLR1C1
NM_005347HSPA51
XM_933553LOC6463601
XM_944750LOC6515381
NM_004804CIAO11
NM_020348CNNM11
NM_015865SLC14A11
NM_024334TMEM431
NM_019001XRN11
NM_001042604XRN11
XM_001132972LOC7291871
XM_001132549LOC7311801
NM_001932MPP31
NM_005370RAB8A1
NM_133647SLC12A61
NM_001042495SLC12A61
NM_001042494SLC12A61
NM_001042497SLC12A61
NM_005135SLC12A61
NM_001042496SLC12A61
NM_007033RER11
NM_033138CALD11
NM_033139CALD11
NM_004342CALD11
NM_033157CALD11
NM_033140CALD11
NM_052913KIAA19131
NM_015359SLC39A141
NM_005721ACTR31
NM_144498OSBPL21
NM_014835OSBPL21
NM_003651CSDA1
NM_182729TXNRD11
NM_0010937711
NM_182742TXNRD11
NM_003330TXNRD11
NM_182743TXNRD11
XM_001134423C9orf1441
NM_004279PMPCB1
NM_003021SGTA1
NM_198859PRICKLE21
NM_144642SYNPR1
NM_178844NLRC31
NM_000843GRM61
NM_007374SIX61
NM_002181IHH1
NM_002903RCVRN1
NM_025179PLXNA21
NM_019036HMGCLL11
NM_001042406HMGCLL11
NM_014553TFCP2L11
NM_0152971
NM_005461MAFB1
NM_183373C6orf1451
XM_937537C6orf1451
NM_024567HMBOX11
NM_001012981ZKSCAN21
NM_207364GPR1481
NM_012425RSU11
NM_152724RSU11
NM_006591POLD31
NM_005759ABI21
XM_001126750ABI21
NM_000388CASR1
NM_001718BMP61
NM_153747PIGC1
NM_002642PIGC1
NM_001007271DUSP131
NM_152388ALS2CR41
NM_001044385ALS2CR41
NM_001008539SLC7A21
NM_003046SLC7A21
NM_002390ADAM111
NM_001012508SPRN1
NM_014956CEP1641
NM_018934PCDHB141
NM_002928RGS161
NM_021111RECK1
NM_012125CHRM51
NM_020782KLHDC51
XM_166659OTUD11
XM_001134465OTUD11
NM_198461LONRF21
NM_001032392PLGLB11
NM_002665PLGLB21
NM_003675PRPF181
NM_012134LMOD11
NM_201431RASSF61
NM_177532RASSF61
NM_001729BTC1
NM_016018PHF20L11
NM_014838ZBED41
NM_015266SLC9A81
NM_001012511GOSR21
XM_001131480ALOX151
NM_170774RASSF21
NM_014737RASSF21
NM_018121C10orf61
NM_020360PLSCR31
NM_024933ANKRD531
NM_017633FAM46A1
NM_019616F71
NM_000131F71
NM_001077503TAC41
NM_001077505TAC41
NM_170685TAC41
NM_001077506TAC41
NM_001077504TAC41
NM_015084MRPS271
NM_153708RTP11
NM_0010996781
NM_133457EMID21
NM_000447PSEN21
NM_012486PSEN21
NM_006724MAP3K41
NM_005922MAP3K41
NM_001048209HNT1
NM_016522HNT1
NM_017705PAQR51
NM_0011045541
NM_138413C10orf651
NM_0010986381
XM_944198LOC4002361
XM_378472LOC4002361
NM_178507OAF1
NM_198441FLJ402961
XM_001132957LOC7292401
XM_001132952LOC7292331
XM_001132961LOC7292461
XM_001132965LOC7292501
NM_018704CTTNBP2NL1
NM_173547TRIM651
NM_006553SLMO11
NM_005795CALCRL1
NM_0150361
NM_007368RASA31
NM_139155ADAMTS141
NM_080722ADAMTS141
NM_018110DOK41
NM_001007246BRWD11
NM_138959VANGL11
NM_053056CCND11
NM_032199ARID5B1
NM_134270SMTN1
NM_134269SMTN1
NM_006932SMTN1
NM_030576LIMD21
NM_005748YAF21
NM_006133DAGLA1
NM_182848CLDN101
NM_006984CLDN101
NM_032452JPH41
NM_001029871RSPO41
NM_001040007RSPO41
NM_032512PDZD41
NM_0010994391
NM_018049PLEKHJ11
NM_007118TRIO1
NM_005630SLCO2A11
XM_001130121LOC7293851
NM_198148CPXM21
NM_024033C7orf491
NM_182749N6AMT11
NM_013240N6AMT11
NM_017791C14orf581
NM_005502ABCA11
NM_181777UBE2A1
NM_181762UBE2A1
NM_003336UBE2A1
NM_020776KIAA13281
NM_014048MKL21
NM_007014WWP21
NM_199424WWP21
NM_024607PPP1R3B1
NM_015328KIAA08281
NM_203405KRTAP26-11
NM_001018057DKK31
NM_013253DKK31
NM_015881DKK31
NM_004643PABPN11
NM_013313YPEL11
NM_0153061
XM_001134096LOC7299641
XM_001134032LOC7321421
NM_138292ATM1
NM_000051ATM1
NM_003648DGKD1
NM_152879DGKD1
NM_005856RAMP31
NM_032689ZNF6071
NM_152916EMR21
NM_152918EMR21
NM_152917EMR21
NM_152920EMR21
NM_152921EMR21
NM_013447EMR21
NM_152919EMR21
NM_004293GDA1
NM_006175NRAP1
NM_198060NRAP1
NM_022140EPB41L4A1
NM_015044GGA21
NM_017745BCOR1
NM_015151DIP2A1
NM_0011003981
NM_015085GARNL41
NM_001077263TMPRSS131
NM_013399C16orf51
XM_934619LOC2845771
XM_945015LOC2845771
NM_015125CIC1
XM_001133503LOC6450271
XM_042978FRMPD31
XM_937007FRMPD31
XM_001127087FLJ439501
NM_001080398KIAA03681
XM_001131778KIAA03681
NM_017654SAMD91
NM_006306SMC1A1
NM_013402FADS11
NM_001085SERPINA31
NM_030761WNT41
NM_000742CHRNA21
NM_000430PAFAH1B11
NM_001017395TMCC11
NM_015008TMCC11
NM_006323SEC24B1
NM_001042734SEC24B1
NM_144597C15orf401
NM_012214MGAT4A1
NM_005910MAPT1
NM_016841MAPT1
NM_016834MAPT1
NM_016835MAPT1
NM_020964KIAA16321
NM_033121ANKRD13A1
NM_014460CSDC21
NM_030802FAM117A1
NM_175922MGC353081
NM_145861EDARADD1
NM_080738EDARADD1
NM_144628TBC1D201
NM_033158HYAL21
NM_003773HYAL21
NM_020219CEACAM191
NM_0155661
NM_144767AKAP131
NM_006738AKAP131
NM_007200AKAP131
NM_003347UBE2L31
NM_198157UBE2L31
NM_006943SOX121
NM_183361DTNB1
NM_021907DTNB1
NM_033147DTNB1
NM_033148DTNB1
NM_183360DTNB1
NM_175575WFIKKN21
NM_005904SMAD71
NM_001001549GRB101
NM_001001555GRB101
NM_001001550GRB101
NM_005311GRB101
NM_001083913C10orf261
NM_017787C10orf261
NM_006674HCP51
NM_024086METT10D1
NM_012309SHANK21
NM_001013842C8orf581
NM_017413APLN1
NM_015286DMN1
NM_145728DMN1
NM_0011128081
NM_015978TNNI3K1
NM_020888KIAA15221
NM_014213HOXD91
NM_0010993341
NM_181725METTL2A1
NM_001005372METTL2A1
NM_018396METTL2B1
NM_005239ETS21
NM_001010867C1orf691
NM_006505PVR1
NM_032824TMEM87B1
NM_000616CD41
XM_001132826LOC7301841
XM_001132908LOC7323461
NM_173681ATG9B1
NM_007350PHLDA11
NM_003482MLL21
NM_001003704MTP181
NM_016498MTP181
NM_172241CTAGE11
NM_198526ZNF7101
NM_006829C10orf1161
NM_000437PAFAH21
NM_015264C22orf91
NM_001009880C22orf91
NM_001078171FAM127A1
NM_001078172FAM127B1
NM_0011001211
NM_0011001201
NM_014693ECE21
NM_001037324ECE21
NM_178457C20orf1741
NM_020158EXOSC51
NM_018667SMPD31
NM_147129ALS2CL1
NM_182775ALS2CL1
NM_0010997841
NM_002531NTSR11
NM_005972PPYR11
NM_004728DDX211
NM_032966BLR11
NM_001716BLR11
NM_004420DUSP81
NM_022912REEP11
NM_022965FGFR31
NM_000142FGFR31
NM_015584POLDIP21
NM_015993PLLP1
NM_016547SDF41
NM_0011003901
NM_152558IQCE1
NM_178496C3orf591
NM_032457PCDH71
NM_138782FCHO21
NM_014056HIGD1A1
NM_0010996681
NM_0010996691
NM_020411XAGE11
NM_133430XAGE11
NM_0010975981
NM_0010975971
NM_0010975931
NM_0010976051
NM_0010975921
NM_0010975911
NM_0010975951
NM_0010975961
NM_133431XAGE11
NM_0010976021
NM_0010976031
NM_0010975941
NM_0010976041
NM_015124DIP1
NM_001125ADPRH1
NM_004772C5orf131
NM_019014POLR1B1
NM_144579SFXN51
NM_153714C10orf671
NM_020676ABHD61
NM_004466GPC51
NM_139235NOL61
NM_022917NOL61
NM_173622CDRT41
NM_002526NT5E1
NM_139135ARID1A1
NM_006015ARID1A1
NM_004661CDC231
NM_178539FAM19A21
NM_001003800BICD21
NM_015250BICD21
NM_001032394GPR1261
NM_020455GPR1261
NM_198569GPR1261
NM_001032395GPR1261
NM_001003793RBMS31
NM_001003792RBMS31
NM_018841GNG121
NM_000902MME1
NM_007289MME1
NM_007288MME1
NM_007287MME1
NM_152470RNF1651
NM_000872HTR71
NM_019859HTR71
NM_019860HTR71
NM_153705KDELC21
NM_014631SH3PXD2A1
NM_001042SLC2A41
NM_015464SOSTDC11
NM_014957DENND31
NM_005253FOSL21
NM_000799EPO1
XM_939663KIAA15531
NM_001080450KIAA15531
NM_017790RGS31
NM_017817RAB201
NM_018306TMEM401
NM_153607LOC1532221
NM_139246C9orf971
NM_016426GTSE11
NM_032900ARHGAP191
NM_139284LGI41
NM_152783D2HGDH1
NM_001033659FLJ358481
NM_005160ADRBK21
NM_005446P2RXL11
XM_001127710LOC7286531
NM_001280CIRBP1
NM_000221KHK1
NM_006488KHK1
NM_199206TCL1B1
NM_004918TCL1B1
XM_943028LOC6477951
NM_0010996841
XM_001126068LOC7278661
XM_001126053LOC7278661
XM_001126035LOC7278661
XM_001126077LOC7278661
NM_014138TMEM291
NM_001543NDST11
NM_014850SRGAP31
NM_001033117SRGAP31
NM_017709FAM46C1
NM_016284CNOT11
XM_001132813LOC7287411
XM_934271LOC3882371
XM_001132780LOC7287341
NM_001018122LOC4403501
NM_000555DCX1
NM_178152DCX1
NM_178153DCX1
NM_178151DCX1
NM_020251ARRB11
NM_004041ARRB11
NM_000337SGCD1
NM_019102HOXA51
NM_199004ARRB21
NM_004313ARRB21
NM_024729MYH141
NM_001077186MYH141
NM_003747TNKS1
NM_001682ATP2B11
NM_001001323ATP2B11
NM_182759FAM19A31
NM_001004440FAM19A31
NM_138409C6orf1171
NM_006256PKN21
NM_016275SELT1
NM_015275KIAA10331
NM_152224PPEF11
NM_152226PPEF11
NM_006240PPEF11
NM_001007224GIMAP61
NM_024711GIMAP61
NM_015439CCDC28A1
NM_194312ESPNL1
NM_145294WDR901
NM_000831GRIK31
NM_000066C8B1
NM_001005217FRG21
XM_936539FLJ205181
XM_941245LOC6519591
XM_209554LOC2852991
XM_936463LOC2852991
NM_002243KCNJ151
NM_170736KCNJ151
NM_170737KCNJ151
NM_014360NKX2-81
NM_024887DHDDS1
NM_205861DHDDS1
NM_014520MYBBP1A1
NM_001439EXTL21
NM_001033025EXTL21
XM_943571LOC6469161
NM_078469BCCIP1
XM_942952FLJ462841
XM_499123FLJ462841
NM_153267MAMDC21
NM_015446AHCTF11
XM_001126456AHCTF11
NM_001039395C9orf681
NM_203341SEP151
NM_004261SEP151
NM_014876JOSD11
NM_018085IPO91
NM_005000NDUFA51
NM_022716PRRX11
NM_006902PRRX11
NM_000163GHR1
NM_018048FLJ102921
NM_173582PGM2L11
NM_207005USF11
NM_007122USF11
NM_152588TMTC21
NM_031296RAB33B1
NM_133448TMEM132D1
NM_022845CBFB1
NM_001755CBFB1
NM_031483ITCH1
NM_013252CLEC5A1
NM_152723CCDC891
NM_177454KIAA19461
NM_002272KRT41
NM_005752CLEC3A1
NM_003817ADAM71
NM_021252RAB181
NM_001204BMPR21
NM_006089SCML21
NM_001079846CREBBP1
NM_004380CREBBP1
NM_015678NBEA1
NM_015111N4BP31
NM_001008493ENAH1
NM_018212ENAH1
NM_001024372BAALC1
NM_024812BAALC1
NM_025000C2orf371
NM_015576ERC21
NM_024007EBF11
NM_017933PID11
NM_0011008181
NM_178818CMTM41
NM_181521CMTM41
NM_001040628NCALD1
NM_001040626NCALD1
NM_001040625NCALD1
NM_032041NCALD1
NM_001040629NCALD1
NM_001040624NCALD1
NM_001040627NCALD1
NM_001040630NCALD1
NM_198581ZC3H61
NM_004947DOCK31
NM_016575NT5DC31
NM_020784KIAA13441
NM_138337CLEC12A1
NM_201623CLEC12A1
NM_018454NUSAP11
NM_016359NUSAP11
NM_001033518WIPI21
NM_001033519WIPI21
NM_015610WIPI21
NM_001033520WIPI21
NM_016003WIPI21
NM_013286RBM15B1
NM_199355ADAMTS181
NM_153035C1orf831
NM_007035KERA1
NM_006922SCN3A1
NM_001081677SCN3A1
NM_001081676SCN3A1
NM_152222TNFRSF19L1
NM_032871TNFRSF19L1
NM_020825CRAMP1L1
NM_004914RAB361
NM_000690ALDH21
NM_199050C21orf251
NM_015500C21orf251
XM_032945C21orf251
NM_004273CHST31
XM_001134123LOC7298371
XM_927734LOC6534981
XM_001134117LOC7298371
XM_001134119LOC7298371
XM_001134124LOC7298371
XM_001134125LOC7298371
XM_001134130LOC7298371
XM_001134128LOC7298371
XM_001134118LOC7298371
XM_001134121LOC7298371
XM_001134131LOC7298371
XM_001134120LOC7298371
NM_001001418TBC1D3C1
NM_032258TBC1D31
XM_934329LOC6533801
XM_934349LOC6533801
XM_934334LOC6533801
XM_930096LOC6533801
XM_001133147LOC6533801
XM_001133134LOC6533801
XM_001134178LOC7298731
XM_001134177LOC7298731
XM_001134175LOC7298731
XM_001134180LOC7298731
XM_001134174LOC7298731
XM_001134196LOC7298771
XM_001134197LOC7298771
XM_001134182LOC7298731
XM_001134185LOC7298731
XM_001134181LOC7298731
XM_001134183LOC7298731
XM_001134198LOC7298771
XM_001134192LOC7298771
XM_001134186LOC7298731
XM_001134201LOC7298771
XM_001134199LOC7298771
XM_001134202LOC7298771
XM_001134176LOC7298731
XM_001134193LOC7298771
XM_001134194LOC7298771
XM_001134200LOC7298771
XM_001125979LOC7277351
XM_001125881LOC7277351
XM_001125868LOC7277351
XM_001125963LOC7277351
XM_001125951LOC7277351
XM_001125829LOC7277351
XM_001125995LOC7277351
XM_001125851LOC7277351
XM_001125897LOC7277351
XM_001125914LOC7277351
XM_001125930LOC7277351
NM_001001417TBC1D3B1
XM_934402TBC1D3I1
NM_001040282TBC1D3G1
XM_930107LOC6533821
NM_198404KCTD41
XM_001132645ODZ31
XM_931600ODZ31
NM_001080477ODZ31
XM_940722ODZ31
NM_182579C1orf1571
NM_021156TXNDC131
NM_0208831
NM_0251851
NM_002828PTPN21
NM_001001682FLJ455301
NM_003099SNX11
NM_152826SNX11
NM_148955SNX11
NM_005506SCARB21
NM_0209111
NM_001034841LOC1620731
NM_014106ZNF7701
NM_152441FBXL141
NM_016496MARCH21
NM_001005415MARCH21
NM_001005416MARCH21
NM_005562LAMC21
NM_0011102131
NM_005042PRH21
NM_000948PRL1
NM_006315PCGF31
NM_000314PTEN1
NM_015347RIMBP21
NM_152376UBXD31
NM_017935BANK11
NM_001083907BANK11
NM_006244PPP2R5B1
NM_006291TNFAIP21
NM_001265CDX21
NM_007286SYNPO1
NM_015267CUTL21
XM_001134449KBTBD91
XM_940375KBTBD91
NM_005707PDCD71
NM_003853IL18RAP1
NM_020374C12orf41
NM_002268KPNA41
XM_936538FAT31
NM_0010087811
XM_926199FAT31
NM_033631LUZP11
NM_015210KIAA08021
NM_003999OSMR1
NM_032532FNDC11
NM_001035223RGL31
NM_001007241GP21
NM_001007242GP21
NM_001007240GP21
NM_001502GP21
NM_133334WHSC11
NM_018373SYNJ2BP1
NM_016733LIMK21
NM_005569LIMK21
NM_005995TBX101
NM_004320ATP2A11
NM_173201ATP2A11
NM_017858TIPIN1
XM_938440LOC4006821
NM_024754PTCD21
NM_000579CCR51
NM_0011001681
NM_0011055361
NM_213609FAM19A11
NM_004318ASPH1
NM_020783SYT41
NM_173344ST3GAL11
NM_003033ST3GAL11
NM_006319CDIPT1
NM_172367TUSC51
NM_152341PAQR41
NM_001029839C3orf231
NM_001029840C3orf231
NM_001004342TRIM671
NM_001037339PDE4B1
NM_002600PDE4B1
NM_001037340PDE4B1
NM_001037341PDE4B1
NM_015621CCDC691
NM_0011016761
NM_005076CNTN21
NM_015172BAT2D11
NM_021815SLC5A71
NM_153456HS6ST31
NM_002731PRKACB1
NM_182948PRKACB1
NM_012465TLL21
NM_016341PLCE11
NM_181351NCAM11
NM_000615NCAM11
NM_198279CXorf231
NM_0011050781
NM_005241EVI11
NM_0011050771
NM_001419ELAVL11
NM_014872ZBTB51
NM_014190ADD11
NM_001119ADD11
NM_014189ADD11
NM_176801ADD11
NM_001013620ALG10B1
NM_001457FLNB1
XM_001129595LOC7291841
XM_001128760LOC7311861
XM_001128652FLJ345151
NM_0059211
NM_014507MCAT1
NM_000745CHRNA51
NM_001042383CEP631
NM_001042400CEP631
NM_025180CEP631
XM_001130722LOC7317691
XM_001127289LOC7283531
NM_175056ZPLD11
NM_153365TAPT11
NM_006920SCN1A1
NM_201544LGALS81
NM_006499LGALS81
NM_201545LGALS81
NM_201543LGALS81
NM_144973MGC240391
NM_001039780FLJ167931
NM_006547IGF2BP31
NM_032167RUNDC2A1
NM_152423MUM1L11
NM_001080975REPS21
NM_004726REPS21
NM_057089AP1S11
NM_001283AP1S11
NM_002977SCN9A1
XM_499042LOC4411671
XM_944526LOC4411671
NM_001018067SERBP11
NM_015640SERBP11
NM_001018069SERBP11
NM_001018068SERBP11
NM_001013626LOC2861871
NM_014616ATP11B1
NM_001005473PLCXD31
XM_001127950LOC7305661
XM_001133333LOC7291721
XM_001125737LOC7302751
NM_0010986721
XM_049078KIAA12391
XM_940885KIAA12391
XM_001134020LOC7318651
NM_013261PPARGC1A1
NM_0011046471
NM_018155SLC25A361
NM_014809KIAA03191
NM_152660FAM76A1
NM_000461THRB1
NM_024896KIAA18151
NM_006203PDE4D1
NM_0011046311
NM_015329KIAA08921
NM_130847AMOTL11
NM_000864HTR1D1
NM_012234RYBP1
NM_0155511
NM_032814TMEM1181
NM_0011099031
NM_016485VTA11
NM_012199EIF2C11
NM_017577GRAMD1C1
NM_147202C9orf251
NM_003780B4GALT21
NM_001005417B4GALT21
NM_001144AMFR1
NM_002711PPP1R3A1
NM_176824BBS71
NM_001006600ERBB2IP1
NM_018695ERBB2IP1
NM_004783TAOK21
NM_004992MECP21
NM_152734C6orf891
NM_001039570KREMEN11
NM_001039571KREMEN11
NM_032105PPP1R12B1
NM_002481PPP1R12B1
NM_181342FKBP71
NM_181798KCNQ11
NM_000218KCNQ11
NM_003298NR2C21
NM_004788UBE4A1
NM_030949PPP1R14C1
NM_003800RNGTT1
NM_0010854601
NM_0010854691
NM_0010854651
NM_0010854661
NM_0010854621
NM_0010854611
NM_0010854581
NM_0010854681
NM_0010854631
NM_0010854671
NM_001331CTNND11
NM_0010854591
NM_0010854641
NM_003108SOX111
NM_020804PACSIN11
NM_175895C12orf611
NM_032866CGNL11
NM_199324OTUD41
NM_0011026531
NM_002356MARCKS1
NM_001620AHNAK1
NM_020718USP311
NM_148894FAM44A1
NM_016009SH3GLB11
NM_178509STXBP41
NM_0011018011
NM_0011018001
NM_016603C5orf51
NM_016032ZDHHC91
NM_001008222ZDHHC91
NM_002199IRF21

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317