Predicted Off-targets for siRNA "aaggccaucgaugcuggauuu" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

21 hits were found for GGCCAUCGAUGCUGGAUUU (14 guide strand hits and 7 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_007163 SLC14A2 2727 2745 GGCCAUCGcUGCaGGAUUU29 2 8   false   <90%   4166
NM_001034842 PTCHD3 272 290 GGCCgUCGAUGCUGGAcga17 4 11 c false   <90%   2369
NM_005135 SLC12A6 1057 1075 GGCCAUCuAUGCUGGAgcc6 4 8 c false   <90%   7327
NM_001042495 SLC12A6 1093 1111 GGCCAUCuAUGCUGGAgcc6 4 8 c false   <90%   7363
NM_001042497 SLC12A6 1187 1205 GGCCAUCuAUGCUGGAgcc6 4 8 c false   <90%   7457
NM_133647 SLC12A6 1232 1250 GGCCAUCuAUGCUGGAgcc6 4 8 c false   <90%   7502
NM_001042494 SLC12A6 1418 1436 GGCCAUCuAUGCUGGAgcc6 4 8 c false   <90%   7688
NM_001042496 SLC12A6 1484 1502 GGCCAUCuAUGCUGGAgcc6 4 8 c false   <90%   7754
NM_018484 SLC22A11 510 528 GGCCAcCGAUGCUGGAcac5 4 10 c false   <90%   2545
NM_007130 ZNF41 657 675 GGCCAUgGAUGCUGGAggg2 4 9 c false   <90%   3172
NM_153380 ZNF41 891 909 GGCCAUgGAUGCUGGAggg2 4 9 c false   <90%   3406
XM_944389 TMEM131 174 192 aGCCAcCaAUGCUGGAUUU-27 3 11 bc false   <90%   6257
XM_371542 TMEM131 174 192 aGCCAcCaAUGCUGGAUUU-27 3 11 bc false   <90%   6257
XM_939932 TMEM131 571 589 aGCCAcCaAUGCUGGAUUU-27 3 11 bc false   <90%   6654


Hits to Sense strand








AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_000991 RPL28 1565 1583 ggAUCCAGCAUCcAUGGCa71 4 10   false   <90%   4243
NM_016298 FBXO40 1637 1655 gguUCCAGCAUCGAUGcCC43 4 13 c false   <90%   3440
XR_018252 LOC347422 111 129 gAAUCCAGCAgCGAUGGag29 4 9 c false   <90%   1988
XR_016128 LOC347422 111 129 gAAUCCAGCAgCGAUGGag29 4 9 c false   <90%   1988
NM_001565 CXCL10 293 311 gAAUCCAGaAUCGAaGGCC13 3 7 c false   <90%   1172
XM_001127580 LOC728505 618 636 AAAUuCAGCAaCGAUGGCa-17 3 7 c false   <90%   965
XM_001126984 LOC730735 618 636 AAAUuCAGCAaCGAUGGCa-17 3 7 c false   <90%   965


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1403
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_052909KIAA19093
NM_001408CELSR23
NM_016577RAB6B3
XM_001125106LOC7304213
NM_033133CNP3
XM_001133002LOC7288043
NM_199340LRRC37A32
NM_001042466PSAP2
NM_002778PSAP2
NM_001042465PSAP2
NM_152375KLHDC7A2
NM_014744TBC1D52
NM_017540GALNT102
NM_198321GALNT102
NM_015193ARC2
NM_033238PML2
NM_032444BTBD122
NM_004187JARID1C2
NM_001039570KREMEN12
NM_001039571KREMEN12
NM_021203SRPRB2
NM_199205KIAA19672
NM_021174KIAA19672
NM_0011096622
NM_002581PAPPA2
NM_017594DIRAS22
NM_080491GAB22
NM_012296GAB22
NM_052848CCDC972
NM_004845PCYT1B2
NM_001039709CBFA2T22
NM_001032999CBFA2T22
NM_005093CBFA2T22
NM_020777SORCS22
NM_033141MAP3K92
NM_001003940BMF2
NM_001003943BMF2
NM_001003942BMF2
NM_033503BMF2
NM_012218ILF32
NM_033551LARP12
NM_015315LARP12
NM_005730CTDSP22
XM_001131899LOC2839042
NM_018420SLC22A152
NM_144571CNOT6L2
NM_004513IL162
NM_172217IL162
NM_002737PRKCA2
NM_0209112
NM_133374ZNF6182
NM_014826CDC42BPA2
NM_003607CDC42BPA2
NM_004771MMP202
NM_172367TUSC52
NM_005189CBX22
NM_145206VTI1A2
NM_001077484SLC38A12
NM_030674SLC38A12
NM_174953ATP2A32
NM_174956ATP2A32
NM_174954ATP2A32
NM_174957ATP2A32
NM_005173ATP2A32
NM_174955ATP2A32
NM_030928CDT12
NM_014723SNPH2
NM_145351SCARF12
NM_145350SCARF12
NM_145349SCARF12
NM_001004106GRK62
NM_002082GRK62
NM_145252LOC1242202
NM_021574BCR2
NM_004327BCR2
NM_005036PPARA2
NM_001001928PPARA2
NM_0010096102
NM_153229TMEM922
NM_153029N4BP12
NM_001003652SMAD22
NM_005901SMAD22
NM_014337PPIL22
NM_148176PPIL22
NM_148175PPIL22
NM_005935AFF12
NM_152253CHKB2
NM_022153C10orf542
NM_016263FZR12
NM_005197CHES12
NM_0010854712
NM_014850SRGAP32
NM_001033117SRGAP32
NM_178136POLDIP32
NM_032311POLDIP32
NM_001009877BRD92
NM_023924BRD92
NM_014809KIAA03192
NM_198977ARHGEF12
NM_004706ARHGEF12
NM_199002ARHGEF12
XM_933701LOC6441652
NM_014661FAM53B2
NM_181521CMTM42
NM_001720BMP8B1
NM_003898SYNJ21
NM_173195KCNIP21
NM_173194KCNIP21
NM_173191KCNIP21
NM_014591KCNIP21
NM_173192KCNIP21
NM_173193KCNIP21
NM_153365TAPT11
NM_054110GALNTL21
NM_018373SYNJ2BP1
NM_020850RANBP101
NM_002402MEST1
NM_177524MEST1
NM_177525MEST1
NM_001037814GAB41
NM_005578LPP1
XM_001128600LOC7311501
XM_001128744LOC7288961
NM_152673MUC201
NM_0010985161
NM_015471NSL11
NM_001042549NSL11
NM_012455PSD41
NM_032047B3GNT51
NM_017637BNC21
NM_012397SERPINB131
NM_005146SART11
NM_003714STC21
NM_145893A2BP11
NM_145892A2BP11
NM_145891A2BP11
XM_945019LOC6434411
XM_933124LOC6434411
NM_0121941
NM_152291MUC71
NM_021648TSPYL41
NM_000750CHRNB41
XM_001129091LOC7312801
NM_014805EPM2AIP11
NM_001010917C10orf1321
NM_002416CXCL91
NM_004848C1orf381
NM_0011055561
NM_001039477C1orf381
NM_017564STAB21
NM_019021C11orf711
NM_004612TGFBR11
NM_014368LHX61
NM_199160LHX61
NM_001014342FLG21
NM_004148NINJ11
NM_015166MLC11
NM_139202MLC11
NM_001025247TAF5L1
XM_001125929LOC7278081
XM_001127286LOC7305641
NM_133334WHSC11
NM_001024596ZNF7721
NM_002427MMP131
NM_004645COIL1
XM_001132474LOC7290761
XM_001133422LOC7317781
XM_001132378PTP4A21
XM_001132367PTP4A21
XM_001132372PTP4A21
XM_001132369PTP4A21
XM_001132357PTP4A21
NM_138727ST7L1
NM_138728ST7L1
NM_017744ST7L1
NM_203382AMACR1
NM_014324AMACR1
NM_025015HSPA12A1
NM_002711PPP1R3A1
NM_130782RGS181
NM_015132SNX131
NM_015191SNF1LK21
NM_013280FLRT11
NM_020754CDGAP1
NM_206922CRIP31
XM_373690LOC3882821
XM_001133719LOC3882821
NM_152388ALS2CR41
NM_001044385ALS2CR41
NM_033437PDE5A1
NM_001083PDE5A1
NM_033430PDE5A1
NM_020347LZTFL11
NM_004273CHST31
NM_004710SYNGR21
NM_018049PLEKHJ11
NM_019035PCDH181
NM_183413FBXO441
NM_033182FBXO441
NM_001014765FBXO441
NM_183412FBXO441
NM_015187KIAA07461
NM_000322PRPH21
NM_006974ZNF33A1
NM_006954ZNF33A1
NM_001031717CRELD11
NM_001077415CRELD11
NM_015513CRELD11
XM_001127175LOC7283201
NM_004186SEMA3F1
NM_001002762DNAJB121
NM_022489C14orf1731
NM_001031714C14orf1731
NM_001042704CLCNKA1
NM_004070CLCNKA1
NM_000085CLCNKB1
NM_002146HOXB31
NM_016335PRODH1
NM_144775SMCR81
XM_927238LOC6439881
XM_936418LOC6473471
NM_017413APLN1
NM_183397PXMP41
NM_007238PXMP41
NM_031283TCF7L11
NM_018200HMG20A1
NM_015316PPP1R13B1
NM_017919STX171
NM_138736GNAO11
NM_016946F11R1
NM_004356CD811
XM_942869BOAT1
XM_292512BOAT1
NM_006454MXD41
NM_001008404LOC4002581
NM_017853TXNL4B1
NM_024949WWC21
NM_203395IYD1
NM_021173POLD41
NM_173808NEGR11
NM_199351C1orf321
NM_002417MKI671
NM_130809PRRC11
NM_145268C7orf451
NM_007212RNF21
NM_0010129941
XM_001125808LOC7277581
NM_152571C9orf1631
NM_006640SEPT91
NM_173495PTCHD11
NM_144570HN1L1
NM_001380DOCK11
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_207119LRRC201
NM_018239LRRC201
NM_018205LRRC201
NM_005785RNF411
NM_194359RNF411
NM_194358RNF411
NM_001005337PKP11
NM_000299PKP11
NM_032283ZDHHC181
NM_005211CSF1R1
NM_145202PRAP11
NM_174902LDLRAD31
NM_014838ZBED41
NM_005852CHD31
NM_001005271CHD31
NM_001005273CHD31
NM_020713ZNF512B1
NM_015635GAPVD11
NM_203463LASS61
NM_006750SNTB21
XM_496034LOC6537171
NM_198586NHLRC11
XM_925864LOC6423251
XM_001130526LOC7286361
XM_001130555LOC7286361
XM_001130543LOC7286361
XM_001130536LOC7286361
XM_001129399LOC6423461
XM_928707LOC6423461
XM_925879LOC6423461
NM_001005473PLCXD31
NM_014216ITPK11
NM_182548LHFPL51
NM_024908WDR761
NM_001031746C10orf721
NM_003281TNNI11
NM_0011111011
NM_014141CNTNAP21
NM_005647TBL1X1
NM_001010866RP13-15M17.21
NM_178583WDFY31
NM_020297ABCC91
NM_021156TXNDC131
NM_030613ZFP21
NM_130847AMOTL11
NM_130783TSPAN181
NM_000073CD3G1
NM_016621PHF21A1
NM_0011018021
NM_012473TXN21
XM_926815LOC6434951
XM_941175LOC6434951
NM_001001711DDI11
NM_145279MOBKL2C1
NM_201403MOBKL2C1
NM_014316CARHSP11
NM_001042476CARHSP11
NM_080621SAMD101
NM_015291DNAJC161
NM_020894KIAA15301
NM_032208ANTXR11
NM_015644TTLL31
NM_001025930TTLL31
NM_005934MLLT11
NM_207316UNQ8461
NM_144691CAPN121
NM_017803DUS2L1
NM_021962ABR1
NM_001092ABR1
NM_032777GPR1241
NM_178126LOC1624271
XM_932563LOC6430081
XM_942645LOC6430081
XM_928053LOC6430081
XM_946181LOC6430081
NM_005550KIFC31
NM_015318ARHGEF181
NM_001040101D4S234E1
NM_014392D4S234E1
NM_004818DDX231
NM_153246MGC454911
NM_015654NAT91
NM_018154ASF1B1
NM_033060KRTAP4-101
NM_0247761
NM_032778MINA1
NM_153182MINA1
NM_001042533MINA1
NM_138733PGK21
NM_152407GRPEL21
NM_138793CANT11
NM_002859PXN1
NM_000396CTSK1
NM_001081491NXF11
XM_059166LOC1276021
XM_938194LOC1276021
NM_005895GOLGA31
XM_001127199LOC7280071
NM_003307TRPM21
NM_032822FLJ146681
XM_938203C1orf1671
XM_209234C1orf1671
NM_003017SFRS31
NM_031467SLC4A91
NM_002081GPC11
NM_0011098101
NM_001042SLC2A41
NM_015270ADCY61
NM_020983ADCY61
NM_032818C9orf1001
NM_138450ARL111
NM_152630FAM46D1
NM_016255FAM8A11
XM_001129820TTC131
NM_024525TTC131
XM_001132771FAM116A1
NM_152678FAM116A1
NM_001007233ERCC81
NM_000082ERCC81
NM_004309ARHGDIA1
NM_017762MTMR101
NM_133490KCNG41
NM_015246MGRN11
NM_014042C11orf511
NM_145174DNAJB71
NM_022131CLSTN21
NM_001039618CREBZF1
NM_001003788LYK51
NM_001003787LYK51
NM_153335LYK51
NM_001003786LYK51
NM_015229KIAA06641
NM_005828WDR681
XM_001132868LOC7301941
XM_001133971LOC7319961
NM_012164FBXW21
NM_0251851
NM_152533C3orf221
NM_001024457RGPD11
NM_033135PDGFD1
NM_025208PDGFD1
NM_006955ZNF33B1
NM_003887DDEF21
NM_003377VEGFB1
XM_001128909VEGFB1
NM_004681EIF1AY1
NM_0011008781
NM_182746MCM41
NM_005914MCM41
NM_174899FBXO361
NM_0010985101
NM_145065PELI31
NM_178014TUBB1
XM_941352LOC2552751
XM_171855LOC2552751
NM_006698BLCAP1
NM_024947PHC31
NM_139169TRUB11
NM_005151USP141
NM_001037334USP141
NM_032689ZNF6071
NM_012409PRND1
NM_001001936AFAP1L21
NM_032550AFAP1L21
NM_017797BTBD21
NM_022787NMNAT11
NM_001004329DBX21
NM_005177ATP6V0A11
NM_139070MAPK91
NM_139068MAPK91
NM_002752MAPK91
NM_139069MAPK91
NM_148169FBXO171
NM_024907FBXO171
NM_005242F2RL11
NM_152342CDYL21
NM_033389SSH21
NM_004379CREB11
NM_134442CREB11
NM_024670SUV39H21
NM_000060BTD1
NM_005783TXNDC91
NM_001031681CTNS1
NM_004937CTNS1
NM_017902HIF1AN1
NM_021144PSIP11
NM_001467SLC37A41
NM_000868HTR2C1
NM_002547OPHN11
NM_152756RICTOR1
NM_024312GNPTAB1
NM_003143SSBP11
NM_020715PLEKHH11
NM_145284FAM122B1
NM_006120HLA-DMA1
NM_005933MLL1
NM_003968UBE1C1
NM_198195UBE1C1
NM_005277GPM6A1
NM_201592GPM6A1
NM_201591GPM6A1
NM_002536TBC1D251
NM_003752EIF3S81
NM_001037808EIF3S81
XM_001132506LOC7286891
XM_001132509LOC7286891
XM_001132505LOC7286891
NM_0010996611
NM_0334031
NM_182744NBL11
NM_005380NBL11
NM_012083FRAT21
NM_018393TCP11L11
NM_194318B3GALTL1
NM_004277SLC25A271
NM_033656BRWD11
NM_005511MLANA1
NM_001011703FAM125B1
NM_207497FLJ437521
NM_021905GABBR11
NM_021904GABBR11
NM_021903GABBR11
NM_001470GABBR11
NM_206891DIP2A1
NM_199175C21orf1231
NM_0011051931
NM_0011051951
NM_0011051941
NM_152698FLJ383771
NM_001564ING21
NM_015055SWAP701
NM_022756C1orf1491
NM_032193RNASEH2C1
NM_032819ZNF3411
NM_194298SLC16A91
NM_003486SLC7A51
NM_152694ZCCHC51
NM_014848SV2B1
NM_032899FAM83A1
NM_138413C10orf651
NM_020718USP311
NM_001007271DUSP131
NM_032809FAM73B1
XM_945536LOC4009601
XM_934552LOC4009601
NM_001632ALPP1
XM_941142FTO1
NM_001080432FTO1
NM_198087ZNF2001
NM_198088ZNF2001
NM_003454ZNF2001
NM_152363ANKRD411
NM_018921PCDHGA91
NM_018923PCDHGB21
NM_018929PCDHGC51
NM_002588PCDHGC31
NM_018917PCDHGA41
NM_018918PCDHGA51
NM_032088PCDHGA81
NM_018915PCDHGA21
NM_018922PCDHGB11
NM_003736PCDHGB41
NM_018927PCDHGB71
NM_018924PCDHGB31
NM_018914PCDHGA111
NM_018920PCDHGA71
NM_018913PCDHGA101
NM_018916PCDHGA31
NM_018926PCDHGB61
NM_003735PCDHGA121
NM_032403PCDHGC31
NM_032092PCDHGA111
NM_018912PCDHGA11
NM_018919PCDHGA61
NM_018925PCDHGB51
NM_018928PCDHGC41
NM_001306CLDN31
NM_015329KIAA08921
NM_030793FBXO381
NM_205836FBXO381
NM_003115UAP11
NM_004215EBAG91
NM_198120EBAG91
NM_004285H6PD1
NM_020170NCLN1
NM_012191NAT61
NM_015326SRGAP21
NM_014338PISD1
NM_0010853861
NM_005014OMD1
NM_021116ADCY11
NM_001042574CRTC31
NM_022769CRTC31
NM_024512LRRC21
NM_006690MMP241
NM_198689KRTAP10-71
NM_032961PCDH101
NM_002959SORT11
NM_198392TCF211
NM_025201PLEKHQ11
NM_016453NCKIPSD1
NM_184231NCKIPSD1
NM_023931ZNF7471
NM_144654C9orf1161
NM_032503MCHR21
NM_001040179MCHR21
NM_001010895LOC3757481
NM_024923NUP2101
NM_001031679MSRB31
NM_198080MSRB31
NM_014762DHCR241
NM_024069C19orf501
NM_006762LAPTM51
NM_004579MAP4K21
NM_182767SLC6A151
NM_207442FLJ397791
NM_002359MAFG1
NM_032711MAFG1
NM_015999ADIPOR11
NM_025220ADAM331
NM_153202ADAM331
NM_001048209HNT1
NM_016522HNT1
NM_007042RPP141
NM_0010987831
NM_001018075NR3C11
NM_001018077NR3C11
NM_001018076NR3C11
NM_001018074NR3C11
NM_001024094NR3C11
NM_000176NR3C11
NM_001020825NR3C11
NM_001485GBX21
NM_170731BDNF1
NM_001709BDNF1
NM_170732BDNF1
NM_170733BDNF1
NM_170734BDNF1
NM_170735BDNF1
NM_031958KRTAP3-11
NM_001760CCND31
NM_001003694BRPF11
NM_004634BRPF11
NM_013361ZNF2231
NM_024866ADM21
NM_152916EMR21
NM_152918EMR21
NM_152917EMR21
NM_152920EMR21
NM_152921EMR21
NM_013447EMR21
NM_152919EMR21
NM_000350ABCA41
NM_014698TMEM63A1
NM_020781ZNF3981
NM_170686ZNF3981
NM_019117KLHL41
NM_021922FANCE1
NM_213589RAPH11
NM_0011055791
NM_031478FAM57B1
NM_133373PLCD31
NM_016575NT5DC31
NM_017991FLJ100811
NM_004807HS6ST11
XM_001132928LOC7289691
NM_001031738TMEM1501
NM_153342TMEM1501
NM_016224SNX91
NM_016598ZDHHC31
NM_001013257BCAM1
NM_017410HOXC131
NM_001040716PC1
NM_000920PC1
NM_022172PC1
NM_175911OR2L131
NM_0010985091
NM_014853RUTBC11
NM_021969NR0B21
NM_032296FLYWCH11
NM_173587RCOR21
NM_145160MAP2K51
NM_002757MAP2K51
NM_018113LMBR1L1
NM_000356TCOF11
NM_001008656TCOF11
NM_006076HRBL1
NM_138353LOC903791
NM_012459TIMM8B1
NM_197941ADAMTS61
NM_003598TEAD21
NM_007067MYST21
NM_182553CNIH21
XM_001129488CNIH21
NM_138983OLIG11
NM_012317LDOC11
NM_003724JRK1
NM_031889ENAM1
NM_033331CDC14B1
NM_003671CDC14B1
NM_001077181CDC14B1
NM_013412RABL2A1
NM_007081RABL2B1
NM_001003789RABL2B1
NM_002926RGS121
XM_001129284LOC7290881
XM_001133596LOC7324301
NM_017813IMPAD11
NM_014964EPN21
NM_0011026641
NM_148921EPN21
NM_000835GRIN2C1
NM_023002HAPLN41
NM_001042371LOC2838711
NM_001042782TNNT31
NM_001042780TNNT31
NM_001042781TNNT31
NM_006757TNNT31
NM_172388NFATC11
NM_006162NFATC11
NM_172389NFATC11
NM_172387NFATC11
NM_024819DCAKD1
NM_032797AIFM21
NM_001004304ZNF7401
NM_152511DUSP181
NM_020338ZMIZ11
NM_002702POU6F11
NM_005140CNGA21
NM_012309SHANK21
NM_145798OSBPL71
NM_033129SCRT21
NM_001927DES1
NM_013943CLIC41
NM_0011031471
NM_0011031481
NM_0011031461
NM_015575TNRC151
NM_018699PRDM51
NM_007261CD300A1
NM_006544EXOC51
NM_024565CCNJL1
NM_032843FIBCD11
NM_022827SPATA201
NM_015050KIAA00821
NM_194312ESPNL1
NM_153714C10orf671
NM_001001668ZNF4701
NM_014286FREQ1
NM_182558C12orf361
NM_014935PLEKHA61
NM_024827HDAC111
NM_001014431AKT11
NM_001014432AKT11
NM_005163AKT11
NM_001569IRAK11
NM_001025243IRAK11
NM_001025242IRAK11
NM_031206LAS1L1
NM_198147LOC1162361
NM_139071SMARCD11
NM_003076SMARCD11
NM_001002857ANXA21
NM_001002858ANXA21
NM_004039ANXA21
NM_020947KIAA16091
NM_003319TTN1
NM_133437TTN1
NM_133378TTN1
NM_133432TTN1
NM_003624RANBP31
NM_015305ANGEL11
NM_022062PKNOX21
NM_175747OLIG31
NM_001007139IGF21
NM_000612IGF21
NM_015124DIP1
NM_000990RPL27A1
NM_080829C20orf1751
NM_015144ZCCHC141
NM_145171GPHB51
NM_001004125TUSC11
NM_001001331ATP2B21
NM_001683ATP2B21
NM_000911OPRD11
XM_934649C1orf341
XM_945958C1orf341
NM_177999ASB61
NM_005336HDLBP1
NM_203346HDLBP1
NM_004914RAB361
NM_001033667LY91
XM_944216LOC6504841
XM_374162LOC3893701
XM_001128649LOC7288901
XM_001125920LOC7278561
XM_376814MGC130051
NM_015079TBC1D2B1
NM_022766CERK1
NM_001023571IQCB11
NM_001023570IQCB11
NM_199262SP61
NM_000478ALPL1
NM_203412UBL4B1
NM_001007156NTRK31
NM_005465AKT31
NM_138619GGA31
NM_014001GGA31
NM_021615CHST61
NM_173664ARL101
NM_152913TMEM1301
NM_004621TRPC61
NM_144625WDR641
NM_000219KCNE11
NM_002570PCSK61
NM_138319PCSK61
NM_001080498EMR41
NM_001045477FAM22G1
NM_032561C22orf231
NM_0152411
XM_001128811LOC7312101
NM_021943ZFAND31
NM_020888KIAA15221
NM_014944CLSTN11
NM_001009566CLSTN11
NM_025081KIAA13051
NM_015268DNAJC131
NM_032105PPP1R12B1
NM_002481PPP1R12B1
NM_032294CAMKK11
NM_172206CAMKK11
NM_000757CSF11
NM_172211CSF11
NM_014773KIAA01411
NM_004090DUSP31
NM_001003674C18orf11
NM_181483C18orf11
NM_181481C18orf11
NM_001003675C18orf11
NM_004338C18orf11
NM_181482C18orf11
NM_015141GPD1L1
NM_001003808LOC3394571
NM_003957BRSK21
NM_002651PIK4CB1
NM_022464SIL11
NM_001037633SIL11
NM_020120UGCGL11
NM_001025777UGCGL11
NM_022773TMEM1121
NM_012294RAPGEF51
NM_001030001RPS291
NM_138967SCAMP51
NM_139321ATRN1
NM_012470TNPO31
NM_000195HPS11
NM_145650MUC151
NM_015094HIC21
NM_0011003981
NM_015085GARNL41
NM_025164KIAA09991
XM_946142SHANK31
NM_001080420SHANK31
NM_012305AP2A21
NM_017623CNNM31
NM_199078CNNM31
NM_012231PRDM21
NM_032015RNF261
NM_000608ORM21
NM_000607ORM11
NM_020132AGPAT31
NM_001037553AGPAT31
NM_021813BACH21
NM_182492LRP5L1
NM_015995KLF131
NM_015345DAAM21
NM_004058CAPS1
NM_080590CAPS1
NM_004441EPHB11
NM_014945ABLIM31
NM_020946DENND1A1
NM_153498CAMK1D1
NM_000831GRIK31
NM_014731ProSAPiP11
NM_001039717C4orf291
NM_005707PDCD71
NM_005670EPM2A1
NM_013371IL191
NM_153758IL191
NM_006328RBM141
NM_019079L1TD11
NM_0151771
NM_014767SPOCK21
NM_080821C20orf1081
NM_004097EMX11
NM_012392PEF11
NM_015285WDR71
NM_052834WDR71
NM_002444MSN1
NM_0010992201
NM_013401RAB3IL11
NM_080616C20orf1121
NM_015000STK38L1
NM_001012270BIRC51
NM_001012271BIRC51
NM_001168BIRC51
NM_152880PTK71
NM_002821PTK71
NM_152881PTK71
NM_152882PTK71
NM_003417ZNF2641
NM_000909NPY1R1
XM_942072CPN21
NM_001080513CPN21
NM_022744C16orf581
NM_001776ENTPD11
NM_0010981751
NM_001005505CACNA2D21
NM_006030CACNA2D21
NM_003149STAC1
NM_023072ZSWIM41
NM_207467FLJ355301
NM_002602PDE6G1
NM_020248CTNNBIP11
NM_001012329CTNNBIP11
NM_014431KIAA12741
NM_018234STEAP31
NM_001008410STEAP31
NM_182915STEAP31
XM_001129019SAPS21
NM_003708RDH161
NM_005076CNTN21
NM_023078PYCRL1
NM_002268KPNA41
NM_014977ACIN11
NM_030636KIAA17061
NM_0321101
NM_015393DKFZP564O08231
NM_182520C22orf151
NM_152264SLC39A131
NM_016538SIRT71
NM_001155ANXA61
NM_004033ANXA61
NM_013358PADI11
NM_000093COL5A11
NM_000245MET1
NM_000566FCGR1A1
XM_001133198LOC6444101
NM_001001436LOC3882721
NM_004873BAG51
NM_001015049BAG51
NM_001015048BAG51
NM_001007255KARCA11
NM_013231FLRT21
NM_145039MGC163851
NM_146387MRPL41
NM_015956MRPL41
NM_146388MRPL41
NM_198973MKNK11
NM_058197CDKN2A1
NM_058195CDKN2A1
NM_032039ITFG31
NM_000046ARSB1
NM_198532C19orf351
NM_153219ZNF5241
NM_152450FAM81A1
NM_005044PRKX1
NM_002760PRKY1
NM_006231POLE1
NM_144675GSG1L1
NM_0011097631
NM_152222TNFRSF19L1
NM_032871TNFRSF19L1
NM_023927GRAMD31
NM_148571MRPL271
NM_148570MRPL271
NM_016504MRPL271
XM_001130790KIAA18811
NM_001080400KIAA18811
XM_498704LOC4404981
XM_938817LOC4404981
NM_017438SETD41
NM_003216TEF1
NM_153685C12orf531
NM_024585ARMC71
XM_944029LOC6479791
NM_001759CCND21
NM_002750MAPK81
NM_139047MAPK81
NM_139046MAPK81
NM_139049MAPK81
NM_080797DIDO11
NM_000633BCL21
NM_017766CASZ11
NM_198207LASS11
NM_006487FBLN11
NM_0010982701
NM_002409MGAT31
NM_030762BHLHB31
XM_001130102THRAP51
NM_001040273TYSND11
NM_173555TYSND11
NM_002074GNB11
NM_004259RECQL51
NM_003200TCF31
NM_012429SEC14L21
NM_014732KIAA05131
NM_003985TNK11
NM_024704C20orf231
XM_001128917LOC7312401
XM_001126538LOC7281031
NM_153051MTMR31
NM_021090MTMR31
NM_153050MTMR31
NM_002248KCNN11
NM_012325MAPRE11
NM_000875IGF1R1
NM_024735FBXO311
NM_020783SYT41
NM_014043CHMP2B1
XM_941135LOC6518721
NM_178445CCRL11
NM_016557CCRL11
NM_002420TRPM11
NM_144973MGC240391
NM_016623FAM49B1
NM_032025EIF2A1
NM_022140EPB41L4A1
NM_032456PCDH71
NM_006631ZNF2661
NM_198058ZNF2661
NM_181712ANKRD381
NM_004956ETV11
NM_004541NDUFA11
NM_016101NIP71
NM_000217KCNA11
NM_025136OPA31
NM_018976SLC38A21
NM_006367CAP11
NM_0011055301
NM_020639RIPK41
NM_024602HECTD31
XM_944271USP451
XM_939661USP451
XM_944273USP451
XM_944255USP451
XM_931094USP451
XM_931124USP451
XM_931115USP451
NM_001080481USP451
NM_173536GABRG11
NM_173543DZIP1L1
NM_138786TM4SF181
NM_080605B3GALT61
NM_001009997C10orf621
NM_178003PPP2R41
NM_021131PPP2R41
NM_178000PPP2R41
NM_178001PPP2R41
NM_020954KIAA16181
NM_000202IDS1
NM_000991RPL281
NM_006145DNAJB11
NM_001049SSTR11
NM_016929CLIC51
NM_020663RHOJ1
NM_0010999511
NM_003433ZNF1321
NM_016217HECA1
NM_004863SPTLC21
NM_020680SCYL11
NM_001048218SCYL11
NM_001393ECM21
NM_001012993C9orf1521
NM_030761WNT41
NM_207395ZNF324B1
NM_006995BTN2A21
NM_181531BTN2A21
NM_022169ABCG41
NM_014376CYFIP21
NM_001037332CYFIP21
NM_001037333CYFIP21
NM_000368TSC11
NM_032515BOK1
NM_020778ALPK31
NM_004431EPHA21
NM_170607MLX1
NM_198204MLX1
NM_198205MLX1
NM_213598ZNF5431
NM_006796AFG3L21
NM_0177821
NM_014346TBC1D22A1
NM_017910FLJ206281
NM_005160ADRBK21
NM_018452C6orf351
NM_001771CD221
NM_024847TMC71
NM_018195C11orf571
NM_001082969C11orf571
NM_001082970C11orf571
NM_182970RIMS41
NM_005746PBEF11
NM_017646TRIT11
XM_037557KIAA09841
XM_939476KIAA09841
NM_001949E2F31
NM_004925AQP31
NM_148975MS4A4A1
NM_024021MS4A4A1
NM_014665LRRC141
NM_000602SERPINE11
NM_153271SH3PX31
NM_024653PRKRIP11
NM_015303VPS81
NM_001009921VPS81
NM_000435NOTCH31
NM_022048CSNK1G11
NM_012137DDAH11
NM_000961PTGIS1
NM_016932SIX21
NM_020831MKL11
NM_031890CECR61
NM_139279MCFD21
NM_020443NAV11
NM_001030287ATF31
NM_001674ATF31
NM_004024ATF31
NM_001040619ATF31
NM_001001712LCN101
XM_929034LOC6460741
NM_012288TRAM21
NM_016319COPS7A1
NM_053056CCND11
NM_001433ERN11
NM_005871SMNDC11
NM_022898BCL11B1
NM_138576BCL11B1
NM_018713SLC30A101
NM_145245EVI5L1
NM_012287CENTB21
XM_940609FLJ250761
XM_059689FLJ250761
NM_001082575HRNBP31
NM_032865TNS41
NM_001031680RUNX31
NM_004350RUNX31
NM_0150361
NM_015571SENP61
NM_0011004091
NM_003246THBS11
NM_013399C16orf51
NM_025222TMEM1131
NM_024025DUSP261
NM_007014WWP21
NM_199424WWP21
NM_004475FLOT21
NM_025204TRABD1
NM_013313YPEL11
NM_022459XPO41
XM_929433LOC6440061
XM_939111LOC6500201
NM_002938RNF41
XM_001132373LOC7309941
XM_001130568LOC7283921
XM_001130582LOC7283921
XM_001132379LOC7309941
NM_032495HOP1
NM_139212HOP1
NM_139211HOP1
NM_021020LZTS11
NM_033224PURB1
XM_001131844LOC7320971
XM_001126459LOC7280651
NM_006826YWHAQ1
NM_001014336IL311
NM_153442GPR261
NM_000675ADORA2A1
NM_017708FAM83E1
NM_052907TMEM132B1
NM_005233EPHA31
NM_173359EIF4E31
NM_014868RNF101
NM_152484ZNF5691
NM_003026SH3GL21
NM_030953TIGD61
NM_014388C1orf1071
NM_031954KCTD101
NM_002632PGF1
NM_006999POLS1
NM_016733LIMK21
NM_005569LIMK21
NM_002193INHBB1
NM_018250RC741
NM_015157PHLDB11
NM_020809ARHGAP201
NM_013316CNOT41
NM_015340LARS21
NM_014028OSTM11
NM_138412RDH131
NM_032873STS-11
NM_005491CXorf61
NM_001017980LOC2035471
NM_001969EIF51
NM_183004EIF51
NM_022060ABHD41
NM_198849LOC2835141
NM_015226KIAA03501
NM_0010129671
NM_014634PPM1F1
NM_003681PDXK1
NM_000303PMM21
NM_015063SLC8A21
NM_001080398KIAA03681
XM_001131778KIAA03681
NM_198859PRICKLE21
NM_030767AKNA1
NM_019070DDX491
NM_001042535CENTG31
NM_020405PLXDC11
NM_173691C9orf751
NM_018026PACS11
NM_173832ZFP411
NM_144991C21orf291
NM_0010853631
NM_080668CDCA51
NM_022152TMBIM11
NM_022003FXYD61
NM_005904SMAD71
NM_032493AP1M11
NM_018019MED91
NM_012329MMD1
NM_001080485ZNF2751
NM_015917GSTK11
NM_001008492SEPT21
NM_006155SEPT21
NM_001008491SEPT21
NM_004404SEPT21
NM_000194HPRT11
NM_001039667ANGPTL41
NM_139314ANGPTL41
NM_006598SLC12A71
NM_006052DSCR31
XM_941644LOC3998811
NM_001004023DYRK31
NM_003582DYRK31
NM_016479SCOTIN1
NM_033512TSPYL51
NM_198573C9orf1651
NM_005461MAFB1
NM_000425L1CAM1
NM_024003L1CAM1
NM_031231APBA2BP1
NM_031232APBA2BP1
NM_173627FLJ352201
NM_199320PHF171
NM_002347LY6H1
NM_004442EPHB21
NM_017449EPHB21
NM_130445COL18A11
NM_030582COL18A11
NM_001629ALOX5AP1
NM_006336ZER11
NM_005938MLLT71
NM_003889NR1I21
NM_022002NR1I21
NM_033013NR1I21
NM_031313ALPPL21
NM_019096GTPBP21
NM_152546SRFBP11
NM_024666FLJ115061
NM_005658TRAF11
NM_001018056VLDLR1
NM_003383VLDLR1
NM_017622C17orf591
NM_003408ZFP371
NM_006774INMT1
NM_012334MYO101
NM_004878PTGES1
NM_014600EHD31
NM_002028FNTB1
NM_199242UNC13D1
NM_003369UVRAG1
NM_006800MSL3L11
NM_078630MSL3L11
NM_078629MSL3L11
XM_087225LOC1515071
XM_939716LOC1515071
NM_015059TLN21
NM_001271CHD21
NM_017431PRKAG31
NM_018280C22orf261
NM_013336SEC61A11
NM_001033551TOM1L21
NM_001082968TOM1L21
NM_173542LOC1964631
NM_152557ZNF7461
NM_144638TMEM421
NM_014741KIAA06521
NM_018157RIC8B1
NM_002490NDUFA61
NM_006306SMC1A1
NM_032131ARMC21
NM_006187OAS31
NM_005347HSPA51
NM_005188CBL1
NM_001020821MYADM1
NM_001020818MYADM1
NM_001020819MYADM1
NM_138373MYADM1
NM_001020820MYADM1
NM_181443BTBD31
NM_014962BTBD31
NM_015264C22orf91
NM_001009880C22orf91
NM_016107ZFR1
NM_022145CENPK1
NM_004888ATP6V1G11
NM_020125SLAMF81
NM_004155SERPINB91
NM_001025356TMEM16F1
NM_024805C18orf221
NM_016484PDZD111
NM_0245621
NM_005603ATP8B11
NM_181809BMP8A1
NM_015219EXOC71
NM_001013839EXOC71
NM_014299BRD41
NM_020745AARS21
NM_0011004231
NM_0011004221
NM_0011004241
NM_015535LOC260101
XM_001127262LOC7306671
XM_001133979LOC7297401
NM_145762GFRA41
NM_022139GFRA41
NM_014117C16orf721
NM_002357MXD11
NM_144611CYB5D21
NM_004741NOLC11
NM_030643APOL41
NM_145660APOL41
NM_003942RPS6KA41
NM_001006944RPS6KA41
XM_001130258FAM69B1
NM_134325SLC26A91
NM_052934SLC26A91
NM_014397NEK61
NM_015140TTLL121
NM_003908EIF2S21
NM_173598KSR21
NM_017593BMP2K1
NM_007176C14orf11
NM_199452ZNF3651
NM_199451ZNF3651
NM_020964KIAA16321
NM_001005609EDA1
NM_001399EDA1
NM_173513C2orf521
NM_0324531
NM_001177ARL11
NM_0155621
NM_006281STK31
NM_002264KPNA11
NM_005495SLC17A41
NM_001407CELSR31
NM_014262LEPREL21
NM_173496MPP71
NM_003884PCAF1
NM_001038633RSPO11
NM_020896OSBPL51
NM_145638OSBPL51
NM_0010992891
NM_002265KPNB11
NM_213568SLC39A31
NM_006465ARID3B1
NM_007219RNF241
XM_001128037LOC7286541
XM_001129553LOC7314131
NM_002064GLRX1
NM_001003715RECQL51
NM_001003716RECQL51
NM_022725FANCF1
NM_001852COL9A21
NM_206909PSD31
NM_015310PSD31
NM_152553IBRDC11
NM_001987ETV61
NM_021961TEAD11
NM_001077199SFRS121
NM_139168SFRS121
NM_001005354PRR131
NM_018457PRR131
NM_018427RRN31
NM_014432IL20RA1
XM_930823LOC6423351
XM_943378LOC6423351
NM_003584DUSP111
NM_006675TSPAN91
NM_015833ADARB11
NM_015834ADARB11
NM_001112ADARB11
NM_001033049ADARB11
NM_002857PEX191
NM_172071RC3H11
NM_002390ADAM111
NM_052845MMAB1
NM_001204BMPR21
NM_004028AQP41
NM_001650AQP41
NM_0011128001
NM_021097SLC8A11
NM_0011128011
NM_0011128021
NM_001286CLCN61
NM_001040001MLLT41
NM_031486ZNF4841
NM_001007101ZNF4841
NM_020702KIAA11611
NM_005940MMP111
NM_001039919ZNF3841
NM_001039917ZNF3841
NM_001039916ZNF3841
NM_001039920ZNF3841
NM_133476ZNF3841
NM_001039918ZNF3841
NM_013255MKLN11
NM_199000LHFPL31
NM_006578GNB51
NM_016194GNB51
NM_152244SNX111
NM_013323SNX111
NM_012091ADAT11
NM_001003806TARP1
NM_001003799TARP1
NM_017774CDKAL11
NM_002610PDK11
NM_198389PDPN1
NM_006474PDPN1
NM_001006624PDPN1
NM_001006625PDPN1
NM_001083617RB1CC11
NM_014781RB1CC11
NM_014760TATDN21
NM_145234CHRDL11
NM_012192FXC11
NM_014667VGLL41

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317