VIRsiRNAdb

SpecificityServer - An siRNA design program for determining siRNA specificity
Automatic recommendation
Not OK - siRNA is not specific

28 hits were found for UACACCUCCACCAAAACAU (19 guide strand hits and 9 sense strand hits.)

Hits to Guide strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_199335

FYB

1212

1230

U

c

C

A

C

C

U

C

C

A

C

C

A

A

A

A

C

c

c

80

3

15

ac

false

<90%

4738

NM_001465

FYB

1212

1230

U

c

C

A

C

C

U

C

C

A

C

C

A

A

A

A

C

c

c

80

3

15

ac

false

<90%

4876

NM_015496

KIAA1429

5023

5041

a

A

u

A

C

C

U

C

C

A

C

C

A

A

A

A

C

g

g

70

4

14

c

false

<90%

5786

NM_015655

ZNF337

2774

2792

g

A

C

A

C

C

U

C

C

A

C

C

A

A

A

c

C

u

c

64

4

14

c

false

<90%

3264

NM_001032726

RAB41

591

609

U

u

C

A

C

C

U

C

C

A

C

C

A

A

A

A

g

A

g

60

3

14

ac

false

<90%

1028

XM_001128142

LOC728680

269

287

U

A

C

A

C

C

U

C

C

A

C

a

u

A

A

A

C

A

c

50

3

11

false

<90%

768

XM_001132150

LOC732190

269

287

U

A

C

A

C

C

U

C

C

A

C

a

u

A

A

A

C

A

c

50

3

11

false

<90%

768

XM_001128055

BNC1

2315

2333

U

A

a

A

C

C

U

C

C

A

C

C

A

A

A

A

a

g

c

49

4

13

c

false

<90%

2676

NM_001717

BNC1

2403

2421

U

A

a

A

C

C

U

C

C

A

C

C

A

A

A

A

a

g

c

49

4

13

c

false

<90%

4612

NM_032160

DSEL

1566

1584

c

c

u

A

C

C

U

C

C

A

C

C

A

A

A

g

C

A

U

40

4

12

c

false

<90%

9281

NM_182833

GDPD4

1250

1268

U

c

g

c

C

C

U

C

C

A

C

C

A

A

A

A

C

A

U

32

3

15

bc

false

<90%

2545

XM_944526

LOC441167

211

229

U

g

C

A

C

C

U

C

C

A

a

C

A

A

A

A

C

A

a

22

3

8

c

false

<90%

559

XM_499042

LOC441167

211

229

U

g

C

A

C

C

U

C

C

A

a

C

A

A

A

A

C

A

a

22

3

8

c

false

<90%

559

NM_004071

CLK1

1321

1339

U

g

g

A

C

C

U

C

u

A

C

C

A

A

A

A

C

A

U

8

3

10

bc

false

<90%

1887

XM_495863

GVIN1

6306

6324

g

c

a

A

C

C

U

C

C

A

u

C

A

A

A

A

C

A

U

5

4

8

c

false

<90%

8820

XM_940224

GVIN1

6306

6324

g

c

a

A

C

C

U

C

C

A

u

C

A

A

A

A

C

A

U

5

4

8

c

false

<90%

8820

XR_017719

FLJ43826

1729

1747

U

A

C

A

g

C

U

C

C

u

C

C

A

A

A

A

C

A

c

-39

3

8

bc

false

<90%

2965

XR_017718

FLJ43826

1729

1747

U

A

C

A

g

C

U

C

C

u

C

C

A

A

A

A

C

A

c

-39

3

8

bc

false

<90%

3229

NM_001010913

C1orf140

692

710

c

A

C

A

C

C

a

C

C

c

C

C

A

A

A

A

C

A

U

-51

3

9

bc

false

<90%

4492

Hits to Sense strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_006121

KRT1

441

459

u

g

G

U

U

U

U

G

G

U

G

G

A

G

G

U

G

g

c

78

4

15

ac

false

<90%

2451

NM_031900

AGXT2

1879

1897

A

U

c

U

U

U

U

G

G

U

G

G

A

G

G

U

G

c

c

72

3

14

c

false

<90%

2165

XM_001130369

LOC731656

479

497

u

U

G

U

U

U

U

G

G

U

G

G

A

G

a

U

G

g

A

70

3

13

c

false

<90%

643

NM_014723

SNPH

3811

3829

g

U

G

U

U

U

U

G

G

U

G

G

A

u

G

U

G

a

c

70

4

12

c

false

<90%

5026

NM_000421

KRT10

242

260

A

g

G

U

U

U

U

G

G

U

G

G

A

G

G

U

a

g

c

57

4

14

ac

false

<90%

2145

NM_014982

PCNX

10341

10359

u

c

c

U

U

U

U

G

G

U

G

G

A

G

u

U

G

U

A

42

4

11

c

false

<90%

12936

NR_003233

SNORD113-5

15

33

g

a

G

U

a

U

U

G

G

U

G

G

A

G

G

U

G

U

c

30

4

13

bc

false

<90%

77

NM_152764

C16orf73

1176

1194

u

U

G

U

U

a

U

G

G

U

G

G

A

G

G

U

G

g

u

27

4

11

c

false

<90%

1382

NM_015092

SMG1

12127

12145

A

U

G

U

U

c

U

G

G

U

G

G

A

G

G

U

a

g

A

10

3

10

c

false

<90%

15739

---

3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1149
View matched accessions

3 prime seed match details

Accession	Gene name	Hits to this gene
NM_003395	WNT9A	6
NM_001005473	PLCXD3	4
NM_021629	GNB4	3
XM_001126961	LOC730295	2
XM_001129007	LOC731265	2
NM_000321	RB1	2
NM_020673	RAB22A	2
NM_003498	SNN	2
NM_014160	MKRN2	2
NM_004586	RPS6KA3	2
NM_003417	ZNF264	2
NM_002221	ITPKB	2
NM_001024688	NBN	2
NM_002485	NBN	2
NM_001037293	PALM2	2
NM_053016	PALM2	2
NM_052845	MMAB	2
NM_020922	WNK3	2
NM_001002838	WNK3	2
NM_152261	C12orf23	2
NM_018196	TMLHE	2
NM_020721		2
NM_001032394	GPR126	2
NM_020455	GPR126	2
NM_198569	GPR126	2
NM_001032395	GPR126	2
NM_182752	FAM79A	2
NM_198270	NHS	2
XM_001134060	NHS	2
NM_002913	RFC1	2
NM_018027	FRMD4A	2
NM_002404	MFAP4	2
NM_133370	YTHDC1	2
NM_001031732	YTHDC1	2
NM_025040	ZNF614	2
NM_007030	TPPP	2
NM_017650	PPP1R9A	2
NM_006033	LIPG	2
NM_014810	CEP350	2
NM_001050	SSTR2	2
NM_138959	VANGL1	2
NM_018899	PCDHAC2	2
NM_018900	PCDHA1	2
NM_018902	PCDHA11	2
NM_031849	PCDHA6	2
NM_018905	PCDHA2	2
NM_018904	PCDHA13	2
NM_031860	PCDHA10	2
NM_018907	PCDHA4	2
NM_018909	PCDHA6	2
NM_018910	PCDHA7	2
NM_018911	PCDHA8	2
NM_018906	PCDHA3	2
NM_018903	PCDHA12	2
NM_018898	PCDHAC1	2
NM_031857	PCDHA9	2
NM_031411	PCDHA1	2
NM_018908	PCDHA5	2
NM_018901	PCDHA10	2
NM_001101676		2
NM_022459	XPO4	2
NM_001010000	ARHGAP28	2
NM_005665	EVI5	2
NM_001040429	PCDH17	2
NM_018999	KIAA1128	2
NM_015283		2
NM_006775	QKI	1
NM_002736	PRKAR2B	1
NM_152498	WDR65	1
NM_033132	ZIC5	1
NM_001106	ACVR2B	1
NM_144573	NEXN	1
NM_006524	ZNF138	1
NM_002084	GPX3	1
NM_001100421		1
NM_001100420		1
NM_017447	C21orf91	1
XM_001125807	LOC727870	1
NM_001001396	ATP2B4	1
NM_001684	ATP2B4	1
NM_052968	APOA5	1
NM_017912	HERC6	1
NM_002721	PPP6C	1
NM_022096	ANKRD5	1
NM_198798	ANKRD5	1
NM_024596	MCPH1	1
NM_173808	NEGR1	1
NM_198279	CXorf23	1
NM_017420	SIX4	1
NM_001043318	C14orf43	1
NM_194278	C14orf43	1
NM_001042472	ABHD12	1
NM_001025233	CLLU1	1
XM_942780	SYNPO2	1
NM_002444	MSN	1
NM_018355	ZNF415	1
NM_001482	GATM	1
XM_001134139	LOC144481	1
XM_001128090	LOC144481	1
XM_211749	LOC285047	1
XM_945005	LOC285047	1
NM_014293	NPTXR	1
NM_017707	DDEFL1	1
NM_001010891	MTX3	1
NM_024625	ZC3HAV1	1
NM_016052	RRP15	1
NM_002009	FGF7	1
NM_012216	MID2	1
NM_052817	MID2	1
NM_005497	GJA7	1
NM_001080383	GJA7	1
NM_017416	IL1RAPL2	1
NM_016067	MRPS18C	1
NM_001017440	CALN1	1
NM_031468	CALN1	1
NM_021063	HIST1H2BD	1
NM_014207	CD5	1
NM_173552	C3orf58	1
NM_152455	ZSCAN29	1
NM_001077700	MIER1	1
NM_001077701	MIER1	1
NM_020948	MIER1	1
NM_080666	WDR89	1
NM_001008726	WDR89	1
NM_020346	SLC17A6	1
NM_015634	KIAA1279	1
NM_007043	KRR1	1
NM_004866	SCAMP1	1
NM_001109754		1
NM_002837	PTPRB	1
NM_203395	IYD	1
NM_148964	CTSE	1
NM_001910	CTSE	1
NM_173635	FLJ40235	1
NM_003387	WIPF1	1
NM_001077269	WIPF1	1
NM_024416	OGN	1
NM_014057	OGN	1
NM_033014	OGN	1
NM_032901	C12orf62	1
NM_014683	ULK2	1
NM_021935	PROK2	1
NM_206595	ESRRG	1
NM_001438	ESRRG	1
NM_206594	ESRRG	1
NM_006674	HCP5	1
NM_018328	MBD5	1
NM_015087	SPG20	1
NM_052927		1
NM_014770	CENTG1	1
NM_015075	IQSEC2	1
NM_001111125		1
NM_016545	IER5	1
NM_024085	ATG9A	1
NM_001077198	ATG9A	1
NM_000201	ICAM1	1
NM_006038	SPATA2	1
NM_000038	APC	1
NM_000219	KCNE1	1
NM_003846	PEX11B	1
NM_173546	KLHDC8B	1
NM_021079	NMT1	1
NM_024095	ASB8	1
XM_378399	LOC400099	1
XM_944233	LOC400099	1
NM_000108	DLD	1
NM_024836	ZNF672	1
NM_013261	PPARGC1A	1
NM_145259	ACVR1C	1
NM_001111031		1
NM_001111033		1
NM_001111032		1
NM_207111	TRIAD3	1
NM_207116	TRIAD3	1
NM_000633	BCL2	1
NM_031282	FCRL4	1
NM_145698	ACBD5	1
NM_001042473	ACBD5	1
NM_018072	HEATR1	1
NM_003421	ZNF37A	1
NM_001007094	ZNF37A	1
NM_152723	CCDC89	1
NM_001039591	USP9X	1
NM_001039590	USP9X	1
NM_181706	DPH4	1
NM_001085357		1
NM_181780	BTLA	1
NM_001267	CHAD	1
NM_002832	PTPN7	1
NM_080588	PTPN7	1
NM_003576	STK24	1
NM_001032296	STK24	1
NM_002709	PPP1CB	1
NM_206876	PPP1CB	1
NM_138927	SON	1
NM_153713	LIX1L	1
NM_198057	TSC22D3	1
NM_001015881	TSC22D3	1
NM_004089	TSC22D3	1
NM_032822	FLJ14668	1
NM_005266	GJA5	1
NM_181703	GJA5	1
NM_153273	IHPK1	1
NM_001006115	IHPK1	1
NM_054026	CNOT7	1
NM_006330	LYPLA1	1
NM_138813	ATP8B3	1
NM_015631	C10orf61	1
NM_198471	ANKRD47	1
NM_001289	CLIC2	1
XM_001133335	ULK1	1
NM_013381	TRHDE	1
NM_031845	MAP2	1
NM_031847	MAP2	1
NM_001039538	MAP2	1
NM_002374	MAP2	1
NM_007010	DDX52	1
NM_152300	DDX52	1
XM_944031	LOC644248	1
XM_932073	LOC644248	1
NM_177403	RAB7B	1
NM_001079535	CPEB1	1
NM_001079534	CPEB1	1
NM_030594	CPEB1	1
NM_001079533	CPEB1	1
NM_001042683	SHPRH	1
NM_173082	SHPRH	1
NM_016612	SLC25A37	1
NM_207334	FAM43B	1
XM_049078	KIAA1239	1
XM_940885	KIAA1239	1
NM_006933	SLC5A3	1
NM_013348	KCNJ14	1
NM_170720	KCNJ14	1
NM_021100	NFS1	1
XM_001125792	LOC727834	1
XM_926013	LOC642398	1
NM_022787	NMNAT1	1
NM_022474	MPP5	1
NM_020894	KIAA1530	1
NM_014220	TM4SF1	1
NM_052966	FAM129A	1
NM_005822	DSCR1L1	1
NM_015265	SATB2	1
NM_144949	SOCS5	1
NM_014011	SOCS5	1
XM_001129284	LOC729088	1
XM_001133596	LOC732430	1
NM_001033910	TRAF5	1
NM_145759	TRAF5	1
NM_004619	TRAF5	1
NM_145895	KLK12	1
NM_017779	DEPDC1	1
NM_021734	SLC25A19	1
NM_001378	DYNC1I2	1
XM_001132075	C10orf75	1
XM_001132143	C10orf75	1
NM_002161	IARS	1
NM_013417	IARS	1
NM_145171	GPHB5	1
NM_000663	ABAT	1
NM_020686	ABAT	1
NM_144675	GSG1L	1
NM_001109763		1
NM_016123	IRAK4	1
NM_001002006	NT5C1B	1
NM_033253	NT5C1B	1
NM_020940	KIAA1600	1
NM_001018090	Gcom1	1
NM_001018102	GRINL1A	1
NM_015532	GRINL1A	1
NM_001018091	Gcom1	1
NM_020657	ZNF304	1
NM_025134	CHD9	1
NM_004052	BNIP3	1
NM_001001665	FLJ16008	1
NM_017645	FAM29A	1
NM_002302	LECT2	1
NM_014613	UBXD8	1
NM_139008	HFE	1
NM_139003	HFE	1
NM_139010	HFE	1
NM_139011	HFE	1
NM_139009	HFE	1
NM_000410	HFE	1
NM_139004	HFE	1
NM_139007	HFE	1
NM_139006	HFE	1
NM_001040153	SLAIN1	1
NM_144595	SLAIN1	1
NM_018976	SLC38A2	1
NM_007085	FSTL1	1
NM_004494	HDGF	1
NM_152609	C1orf71	1
NM_001093755		1
NM_001093756		1
NM_024941	FLJ13611	1
NM_001008495	TMEM64	1
NM_005853	IRX5	1
NM_014953	DIS3	1
NM_173601		1
NM_001099650		1
NM_006380	APPBP2	1
NM_145005	C9orf72	1
XM_498907	LOC284998	1
XM_944715	LOC284998	1
NM_007350	PHLDA1	1
NM_015446	AHCTF1	1
XM_001126456	AHCTF1	1
NM_003854	IL1RL2	1
NM_006873	STON1	1
NM_001012339	DNAJA5	1
NM_194283	DNAJA5	1
NM_152626	ZNF92	1
NM_007139	ZNF92	1
NM_006113	VAV3	1
NM_001079874	VAV3	1
NM_003483	HMGA2	1
NM_024670	SUV39H2	1
NM_001039841	FAM7A2	1
NM_006614	CHL1	1
NM_007121	NR1H2	1
NM_017693	BIVM	1
NM_001718	BMP6	1
NM_020810	TRMT5	1
NM_178191	ATPIF1	1
NM_001013693	LDLRAD2	1
NM_000676	ADORA2B	1
NM_001098801		1
NM_152352	C18orf19	1
NM_002578	PAK3	1
NM_001101346		1
NM_138638	CFL2	1
NM_021914	CFL2	1
NM_003549	HYAL3	1
NM_001029884	PLEKHG1	1
NM_001082575	HRNBP3	1
NM_032622	LNX1	1
NM_020420	DAZ4	1
NM_001005375	DAZ4	1
NM_004081	DAZ1	1
NM_001005786	DAZ2	1
NM_020364	DAZ3	1
NM_020363	DAZ2	1
NM_001005785	DAZ2	1
NM_001351	DAZL	1
NM_020662	MRS2L	1
NM_001015508	PURG	1
NM_001080529	WIPF3	1
NM_020844	KIAA1456	1
NM_001099677		1
NM_014282	HABP4	1
NM_000995	RPL34	1
NM_033625	RPL34	1
NM_004473	FOXE1	1
NM_016173	HEMK1	1
XM_946019	LOC650901	1
NM_016284	CNOT1	1
NM_015094	HIC2	1
XM_939315	LOC644150	1
XM_935705	LOC644150	1
NM_007007	CPSF6	1
NM_015695	BRPF3	1
NM_032750	ABHD14B	1
NM_001908	CTSB	1
NM_147781	CTSB	1
NM_147783	CTSB	1
NM_147780	CTSB	1
NM_147782	CTSB	1
NM_015032	APRIN	1
NM_014803	ZNF518	1
NM_020147	THAP10	1
XM_942458	LOC283398	1
XM_208658	LOC283398	1
NM_003471	KCNAB1	1
NM_172159	KCNAB1	1
NM_172160	KCNAB1	1
NM_015111	N4BP3	1
NM_032578	MYPN	1
NM_006581	FUT9	1
NM_020755	SERINC1	1
NM_032997	ZWINT	1
NM_031426	C9orf58	1
NM_005259	GDF8	1
NM_001008657	TCOF1	1
NM_022745	ATPAF1	1
NM_001042546	ATPAF1	1
XM_001127963	LOC730982	1
XM_001127725	LOC728544	1
NM_003634	NIPSNAP1	1
NM_000333	ATXN7	1
NM_012157	FBXL2	1
NM_006546	IGF2BP1	1
NM_001364	DLG2	1
NM_002760	PRKY	1
XM_001125918	LOC727872	1
NM_002241	KCNJ10	1
NM_032552	DAB2IP	1
NM_025224	ZBTB46	1
NM_002074	GNB1	1
XM_379100	LOC400958	1
NM_198484	ZNF621	1
NM_001098414		1
NM_006943	SOX12	1
NM_152407	GRPEL2	1
NM_182526	C14orf83	1
NM_003075	SMARCC2	1
NM_139067	SMARCC2	1
NM_001552	IGFBP4	1
NM_181643	C1orf88	1
NM_013952	PAX8	1
NM_013953	PAX8	1
NM_013951	PAX8	1
NM_003466	PAX8	1
NM_013992	PAX8	1
NM_022112	P53AIP1	1
XM_940069	PPP1R3E	1
XM_927029	PPP1R3E	1
NM_014657	KIAA0406	1
XM_945436	LOC400958	1
NM_014889	PITRM1	1
NM_001007097	NTRK2	1
NM_005683	GPR55	1
XM_938090	PEAR1	1
NM_001080471	PEAR1	1
NM_005840	SPRY3	1
NM_020911		1
NM_025194	ITPKC	1
NM_006826	YWHAQ	1
NM_032538	TTBK1	1
NM_001007534	C3orf56	1
NM_006267	RANBP2	1
NM_004464	FGF5	1
NM_033143	FGF5	1
NM_016468	C14orf112	1
NM_001795	CDH5	1
NM_001005404	YPEL2	1
NM_003083	SNAPC2	1
NM_002204	ITGA3	1
NM_005501	ITGA3	1
NM_002350	LYN	1
NM_001111097		1
NM_000533	PLP1	1
NM_199478	PLP1	1
NM_005197	CHES1	1
NM_001085471		1
NM_012262	HS2ST1	1
NM_012192	FXC1	1
NM_199126	ZNF585A	1
NM_152655	ZNF585A	1
NM_001100425		1
NM_015314	KIAA0895	1
NM_001018067	SERBP1	1
NM_015640	SERBP1	1
NM_001018069	SERBP1	1
NM_001018068	SERBP1	1
NM_020526	EPHA8	1
NM_152400	C4orf32	1
NM_004685	MTMR6	1
NM_006361	HOXB13	1
NM_014868	RNF10	1
NM_015225	KIAA0367	1
NM_014718	CLSTN3	1
XM_001132325	LOC730081	1
XM_001127777	LOC730934	1
NM_201628	FLJ43806	1
NM_005763	AASS	1
NM_133493	CD109	1
NM_001792	CDH2	1
XM_294854	LOC339209	1
XM_944009	LOC339209	1
NM_020975	RET	1
XM_001130526	LOC728636	1
XM_001130555	LOC728636	1
XM_001130543	LOC728636	1
XM_001130536	LOC728636	1
XM_001129399	LOC642346	1
XM_928707	LOC642346	1
XM_925879	LOC642346	1
XM_925864	LOC642325	1
NM_014951	ZNF365	1
NM_020914	RNF213	1
NM_203404	AMPD2	1
NM_139156	AMPD2	1
NM_004037	AMPD2	1
NM_000945	PPP3R1	1
NM_020980	AQP9	1
NM_014047	C19orf53	1
NM_001265	CDX2	1
NM_000674	ADORA1	1
NM_001048230	ADORA1	1
NM_014388	C1orf107	1
NM_015528	RNF167	1
NM_001080975	REPS2	1
NM_004726	REPS2	1
NM_014911	AAK1	1
NM_005225	E2F1	1
NM_138727	ST7L	1
NM_138728	ST7L	1
NM_017744	ST7L	1
NM_016079	VPS24	1
NM_001005753	VPS24	1
NM_198269	HIPK1	1
NM_181358	HIPK1	1
NM_198268	HIPK1	1
NM_022757	CCDC14	1
NM_005932	MIPEP	1
NM_016169	SUFU	1
NM_207440	FLJ26443	1
NM_017919	STX17	1
NM_000574	CD55	1
NM_015141	GPD1L	1
XM_939366	LOC283585	1
XM_375099	LOC283585	1
NM_017460	CYP3A4	1
NM_001988	EVPL	1
NM_018833	TAP2	1
NM_014442	SIGLEC8	1
NM_001012413	SGOL1	1
NM_001012409	SGOL1	1
NM_001012411	SGOL1	1
NM_012316	KPNA6	1
NM_002655	PLAG1	1
NM_181774	SLC36A3	1
NM_016154	RAB4B	1
NM_005032	PLS3	1
NM_032427	MAML2	1
NM_001002762	DNAJB12	1
NM_017626	DNAJB12	1
NM_020826	SYT13	1
NM_033034	TRIM5	1
NM_001080398	KIAA0368	1
XM_001131778	KIAA0368	1
NM_005263	GFI1	1
NM_004035	ACOX1	1
NM_007292	ACOX1	1
NM_138940	CD200R1	1
NM_138939	CD200R1	1
NM_001098805		1
NM_001012419	ANKRD20A3	1
NM_001012421	ANKRD20A2	1
NM_032250	ANKRD20A1	1
NM_144973	MGC24039	1
NM_024989	PGAP1	1
NM_138278	BNIPL	1
NM_001079906	ZNF331	1
NM_018555	ZNF331	1
NM_001079907	ZNF331	1
NM_001649	SHROOM2	1
NM_005368	MB	1
NM_203378	MB	1
NM_203377	MB	1
NM_018947	CYCS	1
NM_018998	FBXW5	1
NM_138347	ZNF551	1
NM_001098787		1
NM_016526	BET1L	1
NM_003863	DPM2	1
NM_001037165	FOXK1	1
NM_001040214	TCBA1	1
NM_182898	CREB5	1
NM_004904	CREB5	1
NM_001011666	CREB5	1
NM_182899	CREB5	1
NM_006108	SPON1	1
NM_018222	PARVA	1
NM_030883	OR2H1	1
NM_002435	MPI	1
NM_152906	C22orf25	1
NM_052863	SCGB3A1	1
NM_000877	IL1R1	1
NM_133369	UNC5A	1
NM_080545	AP1G2	1
NM_003917	AP1G2	1
NM_025220	ADAM33	1
NM_153202	ADAM33	1
XM_932328	LOC283104	1
XM_944648	LOC283104	1
NM_017887	C1orf123	1
NM_212558	LOC401498	1
NM_018667	SMPD3	1
NM_139135	ARID1A	1
NM_006015	ARID1A	1
NM_006721	ADK	1
NM_001123	ADK	1
NM_181308	WDR20	1
NM_144574	WDR20	1
NM_181302	WDR20	1
NM_001008539	SLC7A2	1
NM_003046	SLC7A2	1
NM_001099455		1
NM_018340	FLJ11151	1
NM_000332	ATXN1	1
NM_003729	RTCD1	1
NM_021572	ENPP5	1
NM_015967	PTPN22	1
NM_001109977		1
NM_007050	PTPRT	1
NM_133170	PTPRT	1
NM_006087	TUBB4	1
NM_017712	PGPEP1	1
NM_012266	DNAJB5	1
XM_001130466	DNAJB5	1
NM_207119	LRRC20	1
NM_018239	LRRC20	1
NM_018205	LRRC20	1
NM_018445	SELS	1
NM_178554	KY	1
NM_033121	ANKRD13A	1
NM_001112	ADARB1	1
NM_013306	SNX15	1
NM_147777	SNX15	1
NM_130468	CHST14	1
NM_198829	RAC1	1
NM_006908	RAC1	1
NM_018890	RAC1	1
NM_001100873		1
NM_019117	KLHL4	1
NM_004040	RHOB	1
NM_032236	USP48	1
NM_024738	C12orf49	1
NM_016539	SIRT6	1
NM_174902	LDLRAD3	1
XM_001134313	LOC732291	1
NM_032120	DKFZP564O0523	1
NM_031418	TMEM16C	1
NM_001987	ETV6	1
NM_002069	GNAI1	1
NM_139281	WDR36	1
NM_153029	N4BP1	1
NM_021978	ST14	1
NM_174918	C19orf59	1
NM_014423	AFF4	1
NM_017542	POGK	1
NM_001017395	TMCC1	1
NM_015008	TMCC1	1
NM_004873	BAG5	1
NM_001015049	BAG5	1
NM_001015048	BAG5	1
NM_003603	SORBS2	1
NM_021069	SORBS2	1
NM_003963	TM4SF5	1
NM_001077350	C16orf35	1
NM_001039476	C16orf35	1
NM_053277	CLIC6	1
NM_207517	ADAMTSL3	1
XM_943661	LRRC38	1
XM_059074	LRRC38	1
NM_005748	YAF2	1
NM_015204		1
NM_001013635	LOC387856	1
XM_001128921	LOC387856	1
NM_018184	ARL8B	1
NM_032959	POLR2J2	1
NM_001097615		1
NM_000235	LIPA	1
NM_001110781		1
NM_001083621	ZBTB40	1
NM_014870	ZBTB40	1
NM_020792	AADACL1	1
NM_000860	HPGD	1
NM_015508	TIPARP	1
NM_003904	ZNF259	1
NM_014294	TRAM1	1
NM_180991	SLCO4C1	1
NM_031307	PUS3	1
NM_006432	NPC2	1
NM_001005505	CACNA2D2	1
NM_006030	CACNA2D2	1
NM_173463	DKFZp761B107	1
NM_001031834	LOC286526	1
NM_080879	RAB40A	1
NM_003780	B4GALT2	1
NM_001005417	B4GALT2	1
NM_004689	MTA1	1
NM_052995	CLRN1	1
NM_175058	PLEKHA7	1
NM_002086	GRB2	1
NM_203506	GRB2	1
XM_939770	LOC650683	1
XM_926711	LOC643382	1
NM_017647	FTSJ3	1
NM_000567	CRP	1
NM_004438	EPHA4	1
NM_004913	C16orf7	1
NM_006037	HDAC4	1
NM_017586	C9orf7	1
NM_017451	BAIAP2	1
NM_017837	PIGV	1
NM_033170	B3GALT5	1
NM_033173	B3GALT5	1
NM_033171	B3GALT5	1
NM_006057	B3GALT5	1
NM_033172	B3GALT5	1
NM_144570	HN1L	1
NM_014959	CARD8	1
NM_033448	KRT71	1
NM_172069	PLEKHH2	1
NM_019058	DDIT4	1
NM_133367	PAQR8	1
NM_025090	USP36	1
NM_013943	CLIC4	1
NM_020746	VISA	1
NM_004488	GP5	1
NM_173687	C8orf31	1
NM_152433	KBTBD3	1
NM_198439	KBTBD3	1
NM_001013649	LOC388969	1
NM_003288	TPD52L2	1
NM_199359	TPD52L2	1
NM_199362	TPD52L2	1
NM_199360	TPD52L2	1
NM_199363	TPD52L2	1
NM_199361	TPD52L2	1
NM_080876	DUSP19	1
NM_006854	KDELR2	1
NM_001100603		1
NM_152551	C6orf151	1
NM_198458	ZNF497	1
NM_018439	IMPACT	1
NM_001009899	KIAA2018	1
NM_006915	RP2	1
NM_015506	MMACHC	1
XM_930072	LOC644191	1
XM_932965	LOC645553	1
XM_945010	LOC645553	1
NM_170708	LMNA	1
NM_170707	LMNA	1
NM_020982	CLDN9	1
NM_000459	TEK	1
NM_197941	ADAMTS6	1
NM_032105	PPP1R12B	1
NM_002481	PPP1R12B	1
NM_001098622		1
NM_001003715	RECQL5	1
NM_001003716	RECQL5	1
NM_015299	KIAA0323	1
NM_024807	TREML2	1
NM_001042573	FLJ21865	1
NM_003458	BSN	1
NM_014286	FREQ	1
NM_199287		1
NM_198274	SMYD1	1
NM_016467	ORMDL1	1
XM_001133706	LOC731533	1
NM_003818	CDS2	1
XM_373030	LOC285556	1
XM_939505	LOC285556	1
NM_001001891	TMEM16G	1
NM_022130	GOLPH3	1
NM_030806	C1orf21	1
NM_198868	TBC1D9B	1
NM_015043	TBC1D9B	1
NM_130446	KLHL6	1
NM_020817	KIAA1407	1
NM_016651	DACT1	1
NM_001079520	DACT1	1
NM_015471	NSL1	1
NM_001042549	NSL1	1
NM_000692	ALDH1B1	1
XM_939744	LOC644961	1
XM_930420	LOC644961	1
NM_022103	ZNF667	1
NM_199072	MDFIC	1
NM_199133	LOC134145	1
NM_033505	SELI	1
XM_938365	LOC391169	1
XM_372816	LOC391169	1
NM_001100164		1
NM_001100166		1
NM_014721	PHACTR2	1
NM_001100165		1
NM_182515	ZNF714	1
NM_004707	ATG12	1
NM_001102371		1
NM_024955	FOXRED2	1
NM_001076675	ZNF626	1
NM_001039569	AP1S3	1
NM_015151	DIP2A	1
NM_024771	NAT11	1
NM_001005915	ERBB3	1
XM_001133059	LOC728772	1
XM_001133074	LOC728772	1
XM_001133066	LOC728772	1
NM_145041	TMEM106A	1
NM_001008401	ZNF761	1
NM_001007525	NWD1	1
NM_173078	SLITRK4	1
NM_018200	HMG20A	1
NM_015313	ARHGEF12	1
NM_001002026	CLDN18	1
NM_016369	CLDN18	1
NM_001105207		1
NM_002290	LAMA4	1
NM_001105206		1
NM_020243	TOMM22	1
NM_177452	TRAPPC6B	1
NM_001079537	TRAPPC6B	1
NM_005519	HMX2	1
NM_006572	GNA13	1
NM_002830	PTPN4	1
NM_014397	NEK6	1
XM_930027	LOC151234	1
XM_938725	LOC151234	1
NM_004113	FGF12	1
NM_021032	FGF12	1
NM_021821	MRPS35	1
NM_007038	ADAMTS5	1
NM_004627	WRB	1
NM_024769	ASAM	1
NM_033210	ZNF502	1
NM_032885	ATG4D	1
NM_000778	CYP4A11	1
NM_003094	SNRPE	1
NM_003099	SNX1	1
NM_152826	SNX1	1
NM_148955	SNX1	1
NM_006371	CRTAP	1
XM_001131352	CRTAP	1
XM_291095	LOC339970	1
XM_943391	LOC339970	1
NM_022821	ELOVL1	1
NM_006385	ZNF211	1
NM_198855	ZNF211	1
XM_371176	FLJ41856	1
XM_941062	FLJ41856	1
NM_152682	RWDD4A	1
NM_207395	ZNF324B	1
NM_001079514	UBN1	1
NM_016936	UBN1	1
NM_080659	C11orf52	1
NM_020714	ZNF490	1
NM_001082480	ZNF623	1
NM_014789	ZNF623	1
NM_025000	C2orf37	1
NM_032933	C18orf45	1
XM_376795	FLJ45872	1
XM_940037	FLJ45872	1
NM_017582	UBE2Q1	1
NM_001319	CSNK1G2	1
NM_182907	PRDM1	1
NM_001198	PRDM1	1
NM_005836	HRSP12	1
NM_021205	RHOU	1
NM_017879	ZNF416	1
NM_004344	CETN2	1
NM_000448	RAG1	1
NM_012158	FBXL3	1
NM_000089	COL1A2	1
NM_033512	TSPYL5	1
NM_152613	WBP2NL	1
NM_014867	KBTBD11	1
NM_004077	CS	1
NM_198324	CS	1
NM_005779	LHFPL2	1
NM_004331	BNIP3L	1
NM_198968	DZIP1	1
NM_014934	DZIP1	1
NM_032682	FOXP1	1
NM_005862	STAG1	1
NM_198128	RNF138	1
NM_016271	RNF138	1
NM_000125	ESR1	1
NM_018133	MSL2L1	1
NM_007220	CA5B	1
NM_016281	TAOK3	1
NM_138735	NRXN1	1
NM_004801	NRXN1	1
NM_006754	SYPL1	1
NM_182715	SYPL1	1
NM_176894	P2RY13	1
NM_023914	P2RY13	1
NM_007054	KIF3A	1
NM_003281	TNNI1	1
NM_015555	ZNF451	1
NM_001031623	ZNF451	1
NM_021927	GUF1	1
NM_018100	EFHC1	1
NM_024759	NPAL2	1
NM_001007139	IGF2	1
NM_000612	IGF2	1
NM_170606	MLL3	1
NM_001077349	ZNF682	1
NM_033196	ZNF682	1
NM_138328	RHBDL3	1
NM_000749	CHRNB3	1
NM_006005	WFS1	1
NM_198581	ZC3H6	1
NM_022162	NOD2	1
NM_030640	DUSP16	1
NM_177996	EPB41L1	1
NM_012156	EPB41L1	1
NM_003899	ARHGEF7	1
NM_001100595		1
NM_182620	FAM33A	1
NM_000949	PRLR	1
NM_138290	RPIB9	1
NM_015530	GORASP2	1
NM_145808	MTPN	1
NM_024749	VASH2	1
NM_018319	TDP1	1
NM_001008744	TDP1	1
NM_019857	CTPS2	1
NM_175859	CTPS2	1
NM_020725		1
NM_001546	ID4	1
NM_032486	DCTN5	1
NM_145278	C1orf150	1
NM_145011	ZNF25	1
NM_020179	C11orf75	1
NM_001098272		1
NM_002130	HMGCS1	1
NM_003379	VIL2	1
NM_001111077		1
NM_175910	ZNF493	1
NM_001076678	ZNF493	1
NM_005121	THRAP1	1
XM_001129292	MBOAT2	1
NM_000953	PTGDR	1
NM_018318	CCDC91	1
NM_003326	TNFSF4	1
NM_018484	SLC22A11	1
NM_020337	ANKRD50	1
NM_172128	CAMK2D	1
NM_172127	CAMK2D	1
XM_929032	LOC646071	1
NM_012160	FBXL4	1
NM_001745	CAMLG	1
NM_020394	ZNF695	1
NM_016577	RAB6B	1
NM_018941	CLN8	1
NM_001732	BTN1A1	1
NM_017948	NOL8	1
NM_005493	RANBP9	1
NM_198843	SFTPB	1
NM_000539	RHO	1
NM_145351	SCARF1	1
NM_001001711	DDI1	1
NM_005021	ENPP3	1
NM_007331	WHSC1	1
NM_198887	NUP43	1
NM_006464	TGOLN2	1
NM_052885	SLC2A13	1
NM_014310	RASD2	1
NM_000428	LTBP2	1
NM_004911	PDIA4	1
NM_001039697	SNAPC3	1
NM_001098832		1
NM_032837	FAM104A	1
NM_173605	KCNRG	1
NM_199464	KCNRG	1
XM_945031	LOC643464	1
XM_931563	LOC643464	1
NM_001009993	LOC130074	1
NM_001018116	LOC347273	1
NM_023002	HAPLN4	1
NM_020805	KLHL14	1
NM_013336	SEC61A1	1
NM_206853	QKI	1
NM_206854	QKI	1
NM_206855	QKI	1
NM_138447	ZNF689	1
NM_014191	SCN8A	1
NM_178566	ZDHHC21	1
NM_004948	DSC1	1
NM_024421	DSC1	1
NM_015365	AMMECR1	1
NM_001025580	AMMECR1	1
NM_021233	DNASE2B	1
NM_058248	DNASE2B	1
XM_941554	CCDC85A	1
NM_001080433	CCDC85A	1
NM_053281	DACH2	1
NM_173630	RTTN	1
NM_152429	FGFBP3	1
XM_001128292	LOC728727	1
XM_377073	LOC376475	1
NM_001025109	CD34	1
NM_001773	CD34	1
NM_006451	PAIP1	1
NM_182789	PAIP1	1
NM_183323	PAIP1	1
NM_020796	SEMA6A	1
NM_023929	ZBTB10	1
NM_001105539		1
NM_004687	MTMR4	1
NM_020828	ZFP28	1
NM_001010883	FAM102B	1
NM_148174	AZIN1	1
NM_015878	AZIN1	1
NM_001520	GTF3C1	1
NM_152581	MOSPD2	1
XM_001134426	C12orf37	1
XM_001134418	C12orf37	1
NM_033027	AXUD1	1
NM_153263	ZNF549	1
NM_005376	MYCL1	1
NM_004094	EIF2S1	1
NM_000926	PGR	1
NM_001025108	AFF3	1
NM_002285	AFF3	1
XM_931376	SETD5	1
XM_944260	SETD5	1
XM_931478	SETD5	1
XM_944280	SETD5	1
XM_931417	SETD5	1
XM_944276	SETD5	1
XM_939712	SETD5	1
NM_001080517	SETD5	1
NM_025160	WDR26	1
NM_133464	ZNF483	1
NM_000351	STS	1
NM_001190	BCAT2	1
NM_183245	INVS	1
NM_014425	INVS	1
NM_022454	SOX17	1
NM_032800	C1orf198	1
NM_022719	DGCR14	1
NM_030805	LMAN2L	1
NM_052962	IL22RA2	1
NM_181309	IL22RA2	1
NM_181310	IL22RA2	1
NM_000929	PLA2G5	1
NM_005504	BCAT1	1
NM_024039	MIS12	1
NM_005482	PIGK	1
NM_018557	LRP1B	1
NM_003342	UBE2G1	1
NM_153045	C9orf91	1
NM_152641	ARID2	1
NM_145309	LRRC51	1
NM_015199	ANKRD28	1
NM_176792	MRPL43	1
NM_152381	CMYA3	1
NM_001079810	CMYA3	1
NM_138434	C7orf29	1
NM_001098813		1
NM_015146		1
NM_013286	RBM15B	1
NM_031961	KRTAP9-2	1
NM_031963		1
NM_031962	KRTAP9-3	1
NM_182832	PLAC4	1
NM_020141	C1orf119	1
XM_001125727	LOC727778	1
XM_001125757	LOC727778	1
NM_203284	RBPJ	1
NM_203283	RBPJ	1
NM_015874	RBPJ	1
NM_005349	RBPJ	1
NM_015332	NUDCD3	1
NM_144664	FAM76B	1
NM_001083962		1
NM_003199	TCF4	1
NM_020910		1
NM_080760	DACH1	1
NM_080759	DACH1	1
NM_004392	DACH1	1
NM_014182	ORMDL2	1
NM_007345	ZNF236	1
NM_006948	STCH	1
NM_015285	WDR7	1
NM_052834	WDR7	1
XM_936706	KLHL17	1
NM_198317	KLHL17	1
NM_005575	LNPEP	1
NM_175920	LNPEP	1
NM_213589	RAPH1	1
NM_198904	GABRG2	1
NM_000816	GABRG2	1
NM_198903	GABRG2	1
NM_002019	FLT1	1
NM_002706	PPM1B	1
NM_177969	PPM1B	1
NM_001033557	PPM1B	1
NM_017623	CNNM3	1
NM_199078	CNNM3	1
NM_024949	WWC2	1
NM_181523	PIK3R1	1
NM_181504	PIK3R1	1
NM_181524	PIK3R1	1
NM_005276	GPD1	1
NM_017925	DENND4C	1
NM_001401	EDG2	1
NM_057159	EDG2	1
NM_025222	TMEM113	1
NM_032718	MFSD9	1
NM_004800	TM9SF2	1
NM_002048	GAS1	1
NM_001044	SLC6A3	1
NM_001001557	GDF6	1
XM_209363	SIRPB2	1
XM_939897	SIRPB2	1
NM_001776	ENTPD1	1
NM_001098175		1
NM_173475	DCUN1D3	1
NM_003966	SEMA5A	1
NM_152586	USP54	1
NM_005902	SMAD3	1
NM_012290	TLK1	1
NM_022758	C6orf106	1
NM_024294	C6orf106	1
NM_003406	YWHAZ	1
NM_145690	YWHAZ	1
NM_207645	LOC399947	1
NM_005966	NAB1	1
NM_174962	SSX9	1
NM_173358	SSX7	1
XM_001125936	LOC727837	1
NM_001076682	NCAM1	1
NM_001105079		1
NM_014504	RABGEF1	1
NM_152389	CCDC108	1
NM_014747	RIMS3	1
NM_018370	DRAM	1
NM_152750	FLJ23834	1
NM_020353	PLSCR4	1
NM_020347	LZTFL1	1
NM_030752	TCP1	1
NM_001008897	TCP1	1
NM_015216	HISPPD1	1
XM_939100	MYO5B	1
NM_001080467	MYO5B	1
NM_004593	SFRS10	1
NM_199452	ZNF365	1
NM_199451	ZNF365	1
NM_003185	TAF4	1
NM_003161	RPS6KB1	1
NM_178161	PTF1A	1
NM_001042574	CRTC3	1
NM_022769	CRTC3	1
NM_017798	YTHDF1	1
NM_022461	AZI2	1
NM_019044	CCDC93	1
NM_024503	HIVEP3	1
NM_016486	TMEM69	1
NM_002158	FOXN2	1
NM_006042	HS3ST3A1	1
NM_006661	PDE10A	1
NM_006763	BTG2	1
NM_144996	ARL13B	1
NM_182896	ARL13B	1
NM_018313	PBRM1	1
NM_181042	PBRM1	1
NM_018165	PBRM1	1
NM_003016	SFRS2	1
NM_001530	HIF1A	1
NM_181054	HIF1A	1
NM_030762	BHLHB3	1

---

Immunostimulatory motif search results

UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).

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Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

Parameter	Spec. Score cut-off	Colour	Comment
Hit to same gene		Colour	Hits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit	≥80	Colour	Hits are very likely to cause an off-target effect
Medium scoring hit	<80¸≥40	Colour	Hits with a small chance of causing an off target effect.
Low scoring hit		Colour	Hits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-off	Colour
Match	Colour
Wobble base pairs (G-U)	Colour
Critical bases (none)	Colour
0.6 bits	Colour
0.4 bits	Colour
0.2 bits	Colour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer

For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317