VIRsiRNAdb

SpecificityServer - An siRNA design program for determining siRNA specificity
Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

30 hits were found for AUGAUCCUGAUGACUCAUU (21 guide strand hits and 9 sense strand hits.)

Hits to Guide strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_031414

STK31

1985

2003

A

U

G

A

U

C

C

U

G

A

U

G

g

C

U

C

u

c

a

58

4

12

false

<90%

3244

NM_032944

STK31

2367

2385

A

U

G

A

U

C

C

U

G

A

U

G

g

C

U

C

u

c

a

58

4

12

false

<90%

3616

XM_029101

KIAA0947

4241

4259

A

U

G

c

U

C

C

U

G

A

U

G

A

C

U

C

A

c

a

55

3

13

c

false

<90%

8577

XM_940469

KIAA0947

4550

4568

A

U

G

c

U

C

C

U

G

A

U

G

A

C

U

C

A

c

a

55

3

13

c

false

<90%

8886

NM_000509

FGG

422

440

A

U

a

A

U

C

C

U

G

A

U

G

A

a

U

C

A

U

c

55

3

10

c

false

<90%

1665

NM_021870

FGG

422

440

A

U

a

A

U

C

C

U

G

A

U

G

A

a

U

C

A

U

c

55

3

10

c

false

<90%

1763

NM_003913

PRPF4B

2316

2334

c

U

G

A

U

C

C

U

G

A

U

G

A

C

a

a

A

U

U

47

3

13

c

false

<90%

7482

XM_001131281

GRB14

301

319

u

U

G

A

U

C

C

U

G

A

a

G

A

a

U

C

A

U

U

17

3

9

c

false

<90%

2145

XM_001131269

GRB14

420

438

u

U

G

A

U

C

C

U

G

A

a

G

A

a

U

C

A

U

U

17

3

9

c

false

<90%

2264

NM_004490

GRB14

950

968

u

U

G

A

U

C

C

U

G

A

a

G

A

a

U

C

A

U

U

17

3

9

c

false

<90%

2402

NM_173087

CAPN3

1568

1586

A

U

G

A

c

C

C

U

G

A

U

G

A

C

U

C

g

g

a

17

4

11

c

false

<90%

3040

NM_212465

CAPN3

1637

1655

A

U

G

A

c

C

C

U

G

A

U

G

A

C

U

C

g

g

a

17

4

11

c

false

<90%

3223

NM_024344

CAPN3

1712

1730

A

U

G

A

c

C

C

U

G

A

U

G

A

C

U

C

g

g

a

17

4

11

c

false

<90%

3298

NM_000070

CAPN3

1712

1730

A

U

G

A

c

C

C

U

G

A

U

G

A

C

U

C

g

g

a

17

4

11

c

false

<90%

3316

NM_212467

CAPN3

1915

1933

A

U

G

A

c

C

C

U

G

A

U

G

A

C

U

C

g

g

a

17

4

11

c

false

<90%

3501

NM_212464

CAPN3

1637

1655

A

U

G

A

c

C

C

U

G

A

U

G

A

C

U

C

g

g

a

17

4

11

c

false

<90%

3881

NM_006801

KDELR1

1079

1097

u

U

G

A

U

u

C

U

G

A

U

G

A

C

U

C

g

U

U

11

3

10

c

false

<90%

1575

NM_033272

KCNH7

2935

2953

A

U

G

A

U

C

C

U

G

A

a

G

A

C

U

C

u

g

c

7

4

10

c

false

<90%

4225

XR_018374

LOC441818

359

377

A

U

G

A

U

u

C

U

G

A

U

G

A

C

U

C

u

a

a

5

4

10

c

false

<90%

1424

XR_017309

LOC441818

359

377

A

U

G

A

U

u

C

U

G

A

U

G

A

C

U

C

u

a

a

5

4

10

c

false

<90%

1424

NM_016312

WBP11

1237

1255

A

U

G

A

U

u

C

U

G

A

U

G

A

C

U

C

u

g

a

5

4

10

c

false

<90%

2690

Hits to Sense strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_181042

PBRM1

2372

2390

c

A

U

G

A

G

U

C

A

U

C

A

G

G

A

U

g

A

U

74

2

15

ac

false

<90%

7448

NM_018165

PBRM1

2276

2294

c

A

U

G

A

G

U

C

A

U

C

A

G

G

A

U

g

A

U

74

2

15

ac

false

<90%

7508

NM_018313

PBRM1

2469

2487

c

A

U

G

A

G

U

C

A

U

C

A

G

G

A

U

g

A

U

74

2

15

ac

false

<90%

7545

NM_003371

VAV2

4307

4325

A

A

U

a

A

G

U

C

A

U

C

A

u

G

A

U

C

A

c

47

3

8

false

<90%

4707

NM_015226

KIAA0350

1756

1774

A

A

a

G

A

c

U

C

A

U

C

A

G

G

A

U

C

A

U

17

2

13

bc

false

<90%

6786

NM_014341

MTCH1

1088

1106

c

g

g

G

u

G

U

C

A

U

C

A

G

G

A

U

C

A

U

15

4

14

bc

false

<90%

1890

NM_144767

AKAP13

779

797

A

A

U

G

A

G

U

C

A

a

C

A

G

a

A

U

C

A

c

-7

3

9

c

false

<90%

8081

NM_007200

AKAP13

5988

6006

A

A

U

G

A

G

U

C

A

a

C

A

G

a

A

U

C

A

c

-7

3

9

c

false

<90%

13290

NM_006738

AKAP13

6000

6018

A

A

U

G

A

G

U

C

A

a

C

A

G

a

A

U

C

A

c

-7

3

9

c

false

<90%

13302

---

3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1134
View matched accessions

3 prime seed match details

Accession	Gene name	Hits to this gene
XM_928464	LOC146517	3
NM_001527	HDAC2	3
NM_198887	NUP43	3
NM_003417	ZNF264	3
NM_024408	NOTCH2	2
XM_001133349	NOTCH2	2
NM_016929	CLIC5	2
NM_015210	KIAA0802	2
NM_014157	CCDC113	2
NM_199040	NUDT4	2
NM_019094	NUDT4	2
NM_000254	MTR	2
NM_016422	RNF141	2
NM_080591	PTGS1	2
NM_000962	PTGS1	2
NM_024577	SH3TC2	2
NM_033103	RHPN2	2
NM_005188	CBL	2
NM_022462	HIF3A	2
NM_152794	HIF3A	2
NM_152795	HIF3A	2
NM_001112717		2
NM_001112720		2
NM_014988	DKFZP686A01247	2
NM_001112719		2
NM_001112718		2
NM_182493	MLCK	2
NM_182749	N6AMT1	2
NM_013240	N6AMT1	2
NM_182935	MOBP	2
NM_006815	TMED2	2
NM_199421	SOCS4	2
NM_080867	SOCS4	2
NM_004263	SEMA4F	2
NM_001009909	LUZP2	2
NM_177925	H2AFJ	2
NM_170665	ATP2A2	2
NM_000555	DCX	2
NM_178152	DCX	2
NM_178153	DCX	2
NM_178151	DCX	2
NM_025136	OPA3	2
NM_005803	FLOT1	2
NM_001013717	LOC441108	2
NM_002293	LAMC1	2
NM_198468	C6orf167	2
NM_024318	LILRA6	2
NM_004850	ROCK2	2
NM_018479	ECHDC1	2
NM_001002030		2
NM_001105544		2
NM_001105545		2
NM_007010	DDX52	2
NM_152300	DDX52	2
NM_197970	BOLL	2
NM_033030	BOLL	2
NM_014710	GPRASP1	2
NM_001099410		2
NM_001099411		2
NM_021202	TP53INP2	2
NM_000629	IFNAR1	2
NM_001111283		2
NM_000618	IGF1	2
NM_001111284		2
NM_001032288	UBE2V1	2
NM_001821	CHML	2
NM_001014380	KATNAL1	2
NM_032116	KATNAL1	2
NM_015520	MAGI1	2
NM_001033057	MAGI1	2
NM_016593	CYP39A1	1
NM_153027	FLJ31659	1
NM_022786	ARV1	1
NM_020453	ATP10D	1
NM_014397	NEK6	1
NM_006327	TIMM23	1
NM_153607	LOC153222	1
NM_052932	TMEM123	1
NM_012193	FZD4	1
NM_003034	ST8SIA1	1
XM_001127146	IL7R	1
NM_001105193		1
NM_001105195		1
NM_001105194		1
NM_152698	FLJ38377	1
NM_012232	PTRF	1
NM_002223	ITPR2	1
XM_001128081	LOC440268	1
XM_496063	LOC440268	1
NM_001010984	C1orf124	1
NM_021148	ZNF273	1
NM_001040102	TMEM10	1
NM_033207	TMEM10	1
NM_001040103	TMEM10	1
NM_004525	LRP2	1
NM_003507	FZD7	1
NM_024103	SLC25A23	1
NM_001941	DSC3	1
NM_024423	DSC3	1
NM_152722	HEPACAM	1
XM_001132650	LOC149478	1
XM_001128950	LOC149478	1
NM_018715	RCC2	1
NM_152594	SPRED1	1
NM_001753	CAV1	1
NM_014228	SLC6A7	1
NM_014423	AFF4	1
NM_006196	PCBP1	1
NM_006283	TACC1	1
NM_145913	SLC5A8	1
NM_145259	ACVR1C	1
NM_001111031		1
NM_001111033		1
NM_001111032		1
NM_001040450	FAM63B	1
NM_001040453	FAM63B	1
NM_014345	ZNF318	1
XM_925973	LOC653097	1
NM_005658	TRAF1	1
NM_178033	CYP4X1	1
NM_005497	GJA7	1
NM_001080383	GJA7	1
NM_005168	RND3	1
XM_001131395	LOC729810	1
XM_001126629	LOC730634	1
NM_003743	NCOA1	1
NM_147233	NCOA1	1
NM_147223	NCOA1	1
NM_000818	GAD2	1
NM_006430	CCT4	1
NM_020772	NUFIP2	1
NM_024910	ZNF767	1
NM_005665	EVI5	1
NM_001077523	AP3D1	1
NM_003938	AP3D1	1
NM_025137	SPG11	1
NM_001079539	XBP1	1
NM_005080	XBP1	1
NM_152292	RG9MTD2	1
NM_152556	FLJ31818	1
NM_003856	IL1RL1	1
NM_012309	SHANK2	1
NM_007256	SLCO2B1	1
NM_012333	MYCBP	1
NM_014112	TRPS1	1
NM_002233	KCNA4	1
NM_001005212	OR9Q1	1
NM_012287	CENTB2	1
NM_018440	PAG1	1
NM_001100393		1
NM_001100391		1
NM_173848	LOC138046	1
NM_001100392		1
NM_016125	LOC51136	1
NM_152748	KIAA1324L	1
NM_003441	ZNF141	1
XM_001130020	KIAA1147	1
XM_001130081	KIAA1147	1
NM_001080392	KIAA1147	1
NM_014937	INPP5F	1
NM_024638	QTRTD1	1
NM_004496	FOXA1	1
NM_003463	PTP4A1	1
NM_031302	GLT8D2	1
NM_031469	SH3BGRL2	1
NM_006722	MITF	1
NM_000248	MITF	1
NM_198158	MITF	1
NM_198177	MITF	1
NM_198178	MITF	1
NM_198159	MITF	1
XM_938440	LOC400682	1
NM_015306		1
NM_015455	CNOT6	1
NM_000522	HOXA13	1
NM_007039	PTPN21	1
NM_032173		1
NM_203395	IYD	1
NM_170604	RASGRP4	1
NM_207491	MGC48628	1
NM_015382	HECTD1	1
NM_032449	CC2D1B	1
NM_032982	CASP2	1
NM_032983	CASP2	1
NM_001076675	ZNF626	1
NM_001010846	SHE	1
NM_017489	TERF1	1
NM_003218	TERF1	1
XM_939377	LOC650291	1
XM_208097	LOC283523	1
NM_001040185	ZNF765	1
NM_182524	ZNF595	1
NM_004308	ARHGAP1	1
NM_138572	TBN	1
NM_007048	BTN3A1	1
NM_017964	SLC30A6	1
NM_183397	PXMP4	1
NM_007238	PXMP4	1
XM_937430	LOC648377	1
XM_929253	LOC646316	1
NM_139277	KLK7	1
NM_005046	KLK7	1
NM_024541	C10orf76	1
NM_020714	ZNF490	1
NM_153451	ORAOV1	1
NM_024947	PHC3	1
NM_152475	ZNF417	1
NM_032828	ZNF587	1
NM_001008801	ZNF468	1
NM_199132	ZNF468	1
NM_004171	SLC1A2	1
XM_940069	PPP1R3E	1
XM_927029	PPP1R3E	1
NM_152565	ATP6V0D2	1
XM_001128865	LOC728407	1
NM_004286	GTPBP1	1
NM_139057	ADAMTS17	1
NM_031296	RAB33B	1
NM_016037	UTP11L	1
NM_144974	CCDC122	1
NM_198460	GBP6	1
NM_005513	GTF2E1	1
NM_014959	CARD8	1
NM_173667	FLJ37543	1
NM_001024660	KALRN	1
NM_007064	KALRN	1
NM_198581	ZC3H6	1
NM_001292	CLK3	1
NM_173496	MPP7	1
NM_022451	NOC3L	1
NM_001034	RRM2	1
NM_001080484	KIAA1751	1
XM_936307	KIAA1751	1
NM_020456	C13orf1	1
NM_014935	PLEKHA6	1
NM_001018115	FANCD2	1
NM_017877	C2orf18	1
NM_173531	ZNF100	1
NM_017706	WDR55	1
NM_017662	TRPM6	1
NM_144718	CCDC52	1
NM_005902	SMAD3	1
NM_207404	ZNF662	1
NM_033062	KRTAP4-2	1
NM_032206	NLRC5	1
NM_173513	C2orf52	1
NM_022818	MAP1LC3B	1
NM_173602	DIP2B	1
NM_006951	TAF5	1
NM_001080412	ZBTB38	1
XM_001133510	ZBTB38	1
NM_019090		1
NM_015460	MYRIP	1
NM_001030060	SAMD5	1
NM_173084	TRIM59	1
NM_020715	PLEKHH1	1
NM_144667	FLJ32894	1
NM_002486	NCBP1	1
NM_006581	FUT9	1
NM_004973	JARID2	1
NM_001254	CDC6	1
NM_001031712	TRMT11	1
NM_173572	C10orf93	1
NM_002103	GYS1	1
NM_052931	SLAMF6	1
NM_001077426	ZNF586	1
NM_017652	ZNF586	1
NM_019903	ADD3	1
NM_016824	ADD3	1
NM_001121	ADD3	1
NM_006991	ZNF197	1
NM_144967	FLJ30058	1
NM_001078173	FAM127C	1
NM_018463	ITFG2	1
NM_001001709	FLJ45537	1
XM_001134250	LOC732053	1
XM_001126849	LOC727900	1
XM_001127087	FLJ43950	1
NM_001024372	BAALC	1
NM_024812	BAALC	1
NM_173851	SLC30A8	1
NM_001098814		1
NM_033449	FCHSD1	1
NM_153620	HOXA1	1
NM_005522	HOXA1	1
NM_207306		1
NM_001007098	SCP2	1
NM_024843	CYBRD1	1
NM_002112	HDC	1
XM_930959	LOC400831	1
XM_943808	LOC400831	1
NM_024721	ZFHX4	1
NM_153347	TMEM86A	1
NM_001010874	SRD5A2L2	1
XM_001125792	LOC727834	1
XM_926013	LOC642398	1
NM_001013655	LOC389834	1
NM_138554	TLR4	1
NM_152305	KTELC1	1
NM_005124	NUP153	1
NM_016221	DCTN4	1
NM_017782		1
NM_017590	ZC3H7B	1
NM_001009922	RCHY1	1
NM_001008925	RCHY1	1
NM_015436	RCHY1	1
NM_006653	FRS3	1
NM_178499	CCDC60	1
NM_014571	HEYL	1
NM_004840	ARHGEF6	1
NM_001008492	SEPT2	1
NM_006155	SEPT2	1
NM_001008491	SEPT2	1
NM_004404	SEPT2	1
NM_014335	EID1	1
NM_004843	IL27RA	1
NM_176816	CCDC125	1
NM_022067	C14orf133	1
NM_020349	ANKRD2	1
NM_052906	LRRC62	1
XM_378661	C17orf51	1
XM_944416	C17orf51	1
NM_015156	RCOR1	1
NM_177972	TUB	1
NM_003320	TUB	1
NM_133459	CCBE1	1
NM_016563	RASL12	1
NM_000342	SLC4A1	1
NM_006566	CD226	1
NM_004911	PDIA4	1
NM_001042498	SLC35A2	1
NM_001032289	SLC35A2	1
NM_018425	PI4KII	1
NM_207309	UAP1L1	1
XM_944835	LOC648691	1
NM_018227	UBE1L2	1
NM_001003652	SMAD2	1
NM_005901	SMAD2	1
NM_033437	PDE5A	1
NM_001083	PDE5A	1
NM_033430	PDE5A	1
NM_174977	SEC14L4	1
NM_138801	GALM	1
NM_001098504		1
NM_030881	DDX17	1
NM_001098505		1
NM_006386	DDX17	1
NM_080607	C20orf102	1
NM_005274	GNG5	1
NM_014762	DHCR24	1
NM_001049	SSTR1	1
NM_145168	HSPC105	1
NM_014953	DIS3	1
NM_014181	HSPC159	1
NM_014911	AAK1	1
NM_014660	PHF14	1
NM_019844	SLCO1B3	1
NM_001731	BTG1	1
NM_018304	PRR11	1
NM_015567	SLITRK5	1
NM_006446	SLCO1B1	1
XM_001126961	LOC730295	1
XM_001129007	LOC731265	1
XM_939208	LOC648149	1
XM_001133680	LOC648149	1
NM_004440	EPHA7	1
NM_000322	PRPH2	1
NM_194247	HNRPA3	1
NM_003487	TAF15	1
NM_139215	TAF15	1
NM_025059	C6orf97	1
NM_019009	TOLLIP	1
NM_001001995	GPM6B	1
NM_182756	SPDYA	1
NM_024761	MOBKL2B	1
NM_001098484		1
NM_003759	SLC4A4	1
NM_022140	EPB41L4A	1
NM_014548	TMOD2	1
NM_207303	ATRNL1	1
NM_006371	CRTAP	1
XM_001131352	CRTAP	1
NM_002709	PPP1CB	1
NM_206876	PPP1CB	1
NM_001098620		1
NM_031989	PCBP2	1
NM_005016	PCBP2	1
NM_033026		1
NM_001100621		1
NM_017941	C17orf80	1
NM_001063	TF	1
XM_927936	LOC644841	1
XM_935685	LOC641933	1
XM_938176	LOC644841	1
NM_003714	STC2	1
NM_032181	TMEM166	1
NM_023002	HAPLN4	1
NM_024594	PANK3	1
NM_004399	DDX11	1
NM_030653	DDX11	1
NM_152438	DDX11	1
NM_001776	ENTPD1	1
NM_001098175		1
NM_153266	TMEM151	1
XM_001133285	TMEM151	1
NM_018121	C10orf6	1
NM_033132	ZIC5	1
NM_144664	FAM76B	1
NM_018048	FLJ10292	1
NM_031936	GPR61	1
NM_000291	PGK1	1
NM_020866	KLHL1	1
NM_012164	FBXW2	1
XM_928660	LOC653653	1
XM_939725	LOC654127	1
NM_014877	HELZ	1
NM_022351	EFCBP1	1
NM_004540	NCAM2	1
NM_000112	SLC26A2	1
NM_181654	CPLX4	1
NM_004557	NOTCH4	1
NM_020297	ABCC9	1
NM_006606	RBBP9	1
NM_152309	PIK3AP1	1
NM_145019	FAM124A	1
NM_020848		1
NM_000745	CHRNA5	1
NM_001082534	CA10	1
NM_020178	CA10	1
NM_001082533	CA10	1
NM_052958	C8orf34	1
NM_021067	GINS1	1
NM_015236	LPHN3	1
NM_080872	UNC5D	1
NM_018250	RC74	1
NM_021269	ZNF708	1
NM_015061	JMJD2C	1
NM_001101396		1
NM_133444	ZNF526	1
NM_194320	ZNF169	1
NM_014186	COMMD9	1
NM_001101653		1
XM_942776	SYNPO2	1
XM_936336	SYNPO2	1
NM_133477	SYNPO2	1
XM_940960	LOC651744	1
XM_928125	LOC645086	1
NM_014267	C11orf58	1
NM_173662	RNF175	1
NM_015879	ST8SIA3	1
NM_001040152	PEG10	1
NM_002915	RFC3	1
NM_014039	C11orf54	1
NM_000529	MC2R	1
NM_031935	HMCN1	1
XM_498479	LOC439962	1
NM_007000	UPK1A	1
NM_032214	SLA2	1
NM_175077	SLA2	1
NM_005491	CXorf6	1
NM_000481	AMT	1
XM_943686	SYT7	1
NM_012199	EIF2C1	1
NM_025225	PNPLA3	1
NM_012072	CD93	1
NM_024642	GALNT12	1
NM_001081573	GAB3	1
NM_080612	GAB3	1
NM_207034	EDN3	1
NM_207032	EDN3	1
NM_207033	EDN3	1
NM_001024465	SOD2	1
NM_001024466	SOD2	1
NM_144973	MGC24039	1
NM_001066	TNFRSF1B	1
NM_025218	ULBP1	1
NM_005756	GPR64	1
NM_001079859	GPR64	1
NM_001079858	GPR64	1
NM_001079860	GPR64	1
XM_001133099	LOC339879	1
XM_291054	LOC339879	1
NM_001077401	ACVRL1	1
NM_000020	ACVRL1	1
NM_015271	TRIM2	1
XM_001134072	PSMD12	1
NM_006866	LILRA2	1
NM_015557	CHD5	1
NM_006393	NEBL	1
NM_052918	SORCS1	1
NM_001013031	SORCS1	1
NM_182848	CLDN10	1
NM_006984	CLDN10	1
NM_000544	TAP2	1
NM_016507	CRKRS	1
NM_015083		1
XM_931376	SETD5	1
XM_944260	SETD5	1
XM_931478	SETD5	1
XM_944280	SETD5	1
XM_931417	SETD5	1
XM_944276	SETD5	1
XM_939712	SETD5	1
NM_001080517	SETD5	1
XM_944303	SETD5	1
XM_931455	SETD5	1
XM_931447	SETD5	1
XM_944298	SETD5	1
XM_944295	SETD5	1
XM_931444	SETD5	1
NM_015289	VPS39	1
NM_001076682	NCAM1	1
XM_495908	DDX12	1
NM_001098624		1
NM_033290	MID1	1
NM_000381	MID1	1
NM_006504	PTPRE	1
NM_130435	PTPRE	1
NM_007059	KPTN	1
NM_005857	ZMPSTE24	1
NM_021645	UTP14C	1
NM_020825	CRAMP1L	1
NM_023015	INTS3	1
NM_019099	C1orf183	1
NM_198926	C1orf183	1
NM_000574	CD55	1
NM_015259	ICOSLG	1
NM_018326	GIMAP4	1
NM_018234	STEAP3	1
NM_001008410	STEAP3	1
NM_182915	STEAP3	1
NM_001080745	DGKG	1
NM_001346	DGKG	1
NM_001080744	DGKG	1
NM_003786	ABCC3	1
NM_001093772		1
NM_000222	KIT	1
NM_206943	LTBP1	1
NM_000627	LTBP1	1
NM_014021	SSX2IP	1
NM_004776	B4GALT5	1
NM_031407	HUWE1	1
NM_002181	IHH	1
NM_001077497	PRR3	1
NM_025263	PRR3	1
NM_007137	ZNF81	1
NM_152771	C19orf34	1
NM_001923	DDB1	1
XM_001129467	LOC728468	1
NM_181744	OPN5	1
NM_001030051	OPN5	1
NM_001801	CDO1	1
NM_017734	PALMD	1
NM_206926	SEPN1	1
NM_020451	SEPN1	1
NM_003467	CXCR4	1
NM_001008540	CXCR4	1
XM_001130886	FLJ37034	1
XM_001127207	FLJ37034	1
NM_000943	PPIC	1
NM_006933	SLC5A3	1
NM_030813	CLPB	1
NM_018153	ANTXR1	1
NM_030581	WDR59	1
NM_133496	SLC30A7	1
NM_138693	KLF14	1
NM_004956	ETV1	1
NM_001037558	HEPN1	1
NM_006262	PRPH	1
NM_001039396	MPEG1	1
NM_182574	FLJ36070	1
NM_001031727	MGC3207	1
NM_032285	MGC3207	1
NM_144693	ZNF558	1
NM_022772	EPS8L2	1
XM_001129221	EPS8L2	1
NM_001088	AANAT	1
NM_006287	TFPI	1
NM_015073	SIPA1L3	1
NM_024817	THSD4	1
NM_003406	YWHAZ	1
NM_145690	YWHAZ	1
NM_018640	LMO3	1
NM_001001395	LMO3	1
NM_001011720	XKR9	1
NM_018489	ASH1L	1
NM_015052	HECW1	1
XM_940335	PTPRQ	1
XM_001134446	PTPRQ	1
XM_001134045	LOC729903	1
XM_001133484	LOC731498	1
NM_022898	BCL11B	1
NM_138576	BCL11B	1
NM_015303	VPS8	1
NM_001009921	VPS8	1
NM_001098721		1
NM_001098722		1
NM_004485	GNG4	1
NM_021908	ST7	1
NM_001037954	DIXDC1	1
NM_033425	DIXDC1	1
NM_001007156	NTRK3	1
NM_003693	SCARF1	1
NM_145351	SCARF1	1
NM_145350	SCARF1	1
NM_145349	SCARF1	1
NM_145352	SCARF1	1
NM_001105579		1
NM_020725		1
NM_001101676		1
NM_030571	NDFIP1	1
NM_152850	PIGO	1
NM_032634	PIGO	1
NM_005038	PPID	1
NM_002519	NPAT	1
NM_013411	AK2	1
NM_002731	PRKACB	1
NM_182948	PRKACB	1
NM_007283	MGLL	1
NM_001003794	MGLL	1
NM_016513	ICK	1
NM_014920	ICK	1
NM_173822	FAM126B	1
NM_004661	CDC23	1
NM_018235	CNDP2	1
NM_145279	MOBKL2C	1
NM_201403	MOBKL2C	1
NM_013989	DIO2	1
NM_001007023	DIO2	1
NM_000793	DIO2	1
NM_014098	PRDX3	1
NM_006793	PRDX3	1
NM_014747	RIMS3	1
NM_005475	SH2B3	1
NM_152516	COMMD1	1
NM_018984	SSH1	1
NM_001040429	PCDH17	1
NM_152280	SYT11	1
NM_199144	UBE2V1	1
NM_003349	Kua-UEV	1
NM_199203	Kua-UEV	1
NM_021988	UBE2V1	1
NM_022442	UBE2V1	1
NM_021083	XK	1
NM_017420	SIX4	1
NM_031445	AMMECR1L	1
NM_015386	COG4	1
NM_005988	SPRR2A	1
NM_207163		1
NM_004815	ARHGAP29	1
NM_001024209	SPRR2E	1
NM_020911		1
NM_184234	RBM39	1
NM_004902	RBM39	1
NM_021615	CHST6	1
NM_018988	GFOD1	1
NM_004745	DLGAP2	1
NM_001042705	IQCJ	1
NM_181785	SLC46A3	1
NM_014862	ARNT2	1
NM_014293	NPTXR	1
NM_021961	TEAD1	1
NM_007150		1
NM_001508	GPR39	1
XM_001126290	LOC727908	1
NM_001099267		1
NM_012275	IL1F5	1
NM_173170	IL1F5	1
NM_001017970	TMEM30B	1
NM_001012642	GRAMD2	1
NM_017415	KLHL3	1
NM_032996	CASP9	1
NM_001229	CASP9	1
NM_177424	STX12	1
XM_378914	KIAA0492	1
XM_944290	KIAA0492	1
NM_015097	CLASP2	1
NM_018452	C6orf35	1
NM_014752	SPCS2	1
NM_016653	ZAK	1
NM_145298	APOBEC3F	1
NM_012432	SETDB1	1
NM_000080	CHRNE	1
NM_002688	SEPT5	1
NM_057170	GIT2	1
NM_057169	GIT2	1
NM_014776	GIT2	1
NM_020394	ZNF695	1
NM_018684	KIAA1166	1
NM_001312	CRIP2	1
XM_944531	LOC645949	1
XM_933289	LOC645949	1
NM_001003698	RREB1	1
NM_001003699	RREB1	1
NM_002955	RREB1	1
NM_182531		1
NM_019050	USP53	1
NM_173359	EIF4E3	1
NM_001219	CALU	1
NM_006763	BTG2	1
NM_014803	ZNF518	1
NM_004285	H6PD	1
NM_004863	SPTLC2	1
NM_175078	KRT77	1
NM_030576	LIMD2	1
NM_015946	PELO	1
NM_003924	PHOX2B	1
NM_033033	KRT82	1
NM_000351	STS	1
NM_025185		1
NM_005683	GPR55	1
NM_054035	UNC119	1
NM_007271	STK38	1
NM_001102421		1
NM_001102420		1
NM_006007	ZFAND5	1
NM_181706	DPH4	1
NM_024620	ZNF329	1
NM_145060	C18orf24	1
NM_001039535	C18orf24	1
NM_016946	F11R	1
NM_152914	MGC33894	1
NM_182607	VSIG1	1
NM_032184		1
NM_020834	HOMEZ	1
NM_001039656	MTL5	1
NM_024809	C12orf38	1
NM_004821	HAND1	1
NM_057178	RFFL	1
NM_001017368	RFFL	1
NM_012096	APPL1	1
XM_001126700	LOC728147	1
XM_001126645	LOC730638	1
NM_014828	TOX4	1
NM_004230	EDG5	1
NM_018073	TRIM68	1
XM_940966	LOC647219	1
XM_929835	LOC284023	1
XM_941810	LOC284023	1
NM_015641	TES	1
NM_152829	TES	1
XM_941026	ING5	1
XM_001126273	LOC727773	1
NM_032329	ING5	1
NM_001097638		1
NM_000511	FUT2	1
NM_017680	ASPN	1
NM_016332	SEPX1	1
NM_198968	DZIP1	1
NM_014934	DZIP1	1
NM_003342	UBE2G1	1
NM_199184	C6orf108	1
NM_138575	PGAM5	1
NM_178457	C20orf174	1
NM_139201	GIT2	1
NM_001461	FMO5	1
XM_001130919	LOC729652	1
NM_001029884	PLEKHG1	1
NM_020699	GATAD2B	1
NM_201628	FLJ43806	1
NM_005184	CALM3	1
NM_052886	MAL2	1
NM_000878	IL2RB	1
NM_145206	VTI1A	1
XM_001127362	KIAA0574	1
NM_001003940	BMF	1
NM_001003943	BMF	1
NM_001003942	BMF	1
NM_033503	BMF	1
NM_212558	LOC401498	1
NM_000948	PRL	1
NM_000346	SOX9	1
NM_006644	HSPH1	1
XM_939547	ZNF697	1
NM_001080470	ZNF697	1
NM_022138	SMOC2	1
NM_020846		1
NM_000081	LYST	1
NM_001010853	ACY1L2	1
XM_933646	LOC646484	1
XM_943429	LOC646484	1
NM_000647	CCR2	1
XM_001133430	LOC729230	1
NM_001037317	PAP2D	1
NM_001010861	PAP2D	1
NM_145251	STYX	1
XM_001125680	LOC730432	1
XM_001125705	LOC730432	1
NM_001098816		1
NM_005500	SAE1	1
NM_030664	PTER	1
NM_001001484	PTER	1
NM_030939	C6orf62	1
NM_173598	KSR2	1
XM_941807	NHSL1	1
XM_496826	NHSL1	1
NM_007181	MAP4K1	1
NM_194439	RNF212	1
NM_004411	DYNC1I1	1
NM_005504	BCAT1	1
NM_201548	CERKL	1
NM_181359	IL6R	1
NM_000565	IL6R	1
NM_002390	ADAM11	1
NM_015264	C22orf9	1
NM_001009880	C22orf9	1
NM_212475	FN1	1
NM_212478	FN1	1
NM_212474	FN1	1
NM_212476	FN1	1
NM_002026	FN1	1
NM_212482	FN1	1
NM_024926	TTC26	1
NM_006918	SC5DL	1
NM_001024956	SC5DL	1
NM_138694	PKHD1	1
NM_024948	C10orf97	1
XM_938665	USP6NL	1
NM_001080491	USP6NL	1
XM_927409	USP6NL	1
XM_943800	USP6NL	1
NM_020850	RANBP10	1
NM_018225	SMU1	1
NM_030640	DUSP16	1
NM_003032	ST6GAL1	1
NM_173217	ST6GAL1	1
NM_173216	ST6GAL1	1
NM_001334	CTSO	1
NM_018158	SLC4A1AP	1
NM_014668	GREB1	1
NM_145207	SPATA5	1
NM_001024380	TM2D2	1
NM_078473	TM2D2	1
NM_001024381	TM2D2	1
NM_031940	TM2D2	1
NM_022787	NMNAT1	1
XM_930823	LOC642335	1
XM_943378	LOC642335	1
NM_001855	COL15A1	1
NM_033272	KCNH7	1
NM_005506	SCARB2	1
XM_001130018	LOC731550	1
NM_018390	PLCXD1	1
NM_053064	GNG2	1
NM_015635	GAPVD1	1
NM_138700	TRIM40	1
NM_152716	FLJ36874	1
NM_213589	RAPH1	1
NM_001669	ARSD	1
NM_024818	UBE1DC1	1
NM_198329	UBE1DC1	1
XM_377476	MGC57346	1
NM_006253	PRKAB1	1
NM_016123	IRAK4	1
NM_002147	HOXB5	1
NM_001081552	SPAG11A	1
NM_058200	SPAG11B	1
NM_058202	SPAG11B	1
NM_001011645	AR	1
NM_000044	AR	1
NM_001077203	SENP7	1
NM_020654	SENP7	1
NM_002173	IFNA16	1
NM_014655	SLC25A44	1
NM_000337	SGCD	1
NM_152419		1
NM_001008408	RBM33	1
NM_053043	PRR8	1
NM_014369	PTPN18	1
NM_182485	CPEB2	1
NM_182646	CPEB2	1
NM_133445	GRIN3A	1
NM_005909	MAP1B	1
NM_145025	C6orf199	1
NM_001110781		1
NM_001140	ALOX15	1
XM_001131480	ALOX15	1
NM_080671	KCNE4	1
NM_182500	C2orf50	1
NM_198086	JUB	1
NM_032876	JUB	1
NM_002149	HPCAL1	1
NM_134421	HPCAL1	1
NM_014005	PCDHA9	1
NM_207361	FREM2	1
NM_004857	AKAP5	1
NM_001010935	RAP1A	1
NM_002884	RAP1A	1
NM_001081686	G6PC2	1
NM_021176	G6PC2	1
NM_144586	LYPD1	1
NM_001077427	LYPD1	1
NM_024993	LRRTM4	1
NM_000560	CD53	1
NM_001040033	CD53	1
NM_015234	GPR116	1
NM_001098518		1
NM_019067	GNL3L	1
NM_025107	MYCT1	1
NM_138287	DTX3L	1
NM_004808	NMT2	1
NM_152551	C6orf151	1
NM_001008387	REG3G	1
NM_198448	REG3G	1
NM_012223	MYO1B	1
NM_004514	FOXK2	1
XM_001134363	FOXK2	1
XM_001134364	FOXK2	1
NM_015291	DNAJC16	1
NM_016376	ANKFY1	1
NM_001111040		1
NM_014155	ZBTB44	1
NM_004093	EFNB2	1
NM_017994	C7orf42	1
NM_018150	C1orf164	1
NM_207454	FLJ44815	1
NM_003656	CAMK1	1
NM_018602	DNAJA4	1
NM_032511	C6orf168	1
NM_144982	CCDC131	1
NM_001001420	SMAD5	1
NM_001001419	SMAD5	1
NM_005903	SMAD5	1
NM_053044	HTRA3	1
NM_001991	EZH1	1
NM_020319	ANKMY2	1
NM_004262	TMPRSS11D	1
NM_014405	CACNG4	1
NM_170746	C11orf31	1
NM_006425	SLU7	1
NM_018725	IL17RB	1
NM_207363	NAP5	1
NM_207481	NAP5	1
XM_001134308	LOC732275	1
NM_013238	DNAJC15	1
NM_001083926	ASRGL1	1
NM_025080	ASRGL1	1
NM_016052	RRP15	1
NM_001076552	ACSS2	1
NM_018677	ACSS2	1
NM_032735	BEST3	1
NM_152439	BEST3	1
NM_017645	FAM29A	1
NM_033403		1
NM_001077620	PRCD	1
NM_152388	ALS2CR4	1
NM_001044385	ALS2CR4	1
NM_213606	SLC16A12	1
NM_002123	HLA-DQB1	1
XM_942240	LOC650557	1
NM_015187	KIAA0746	1
NM_021220	OVOL2	1
NM_144682	SLFN13	1
NM_171825	CAMK2A	1
NM_015981	CAMK2A	1
NM_001040214	TCBA1	1
NM_021268	IFNA17	1
NM_021068	IFNA4	1
NM_002171	IFNA10	1
NM_001557	IL8RB	1
NM_207381	TNFAIP8L3	1
NM_020897	HCN3	1
NM_001039844	ACBD7	1
NM_005419	STAT2	1
NM_006620	HBS1L	1
NM_138290	RPIB9	1
NM_002155	HSPA6	1
NM_001010917	C10orf132	1
NM_001012643	LOC339344	1
NM_177999	ASB6	1
NM_017873	ASB6	1
NM_000294	PHKG2	1
XM_929878	LOC646915	1
NM_004727	SLC24A1	1
NM_001099455		1
NM_018340	FLJ11151	1
NM_001233	CAV2	1
NM_198212	CAV2	1
NM_173569		1
NM_022784	IQCH	1
NM_020235	BBX	1
NM_005810	KLRG1	1
NM_004801	NRXN1	1
NM_138735	NRXN1	1
NM_014409	TAF5L	1
NM_004462	FDFT1	1
NM_020918	GPAM	1
NM_024619	FN3KRP	1
NM_015725	RDH8	1
NM_015847	MBD1	1
NM_015845	MBD1	1
NM_015844	MBD1	1
NM_002384	MBD1	1
NM_015846	MBD1	1
XM_943028	LOC647795	1
NM_030806	C1orf21	1
NM_018958	C15orf2	1
NM_001010980	C1orf130	1
NM_020776	KIAA1328	1
NM_032557	USP38	1
NM_003474	ADAM12	1
NM_052831	C6orf192	1
NM_021828	HPSE2	1
NM_001003715	RECQL5	1
NM_001003716	RECQL5	1
NM_005338	HIP1	1
NM_020137	GRIPAP1	1
XM_001130398	LOC731666	1
XM_001131009	LOC729680	1
NM_004106	FCER1G	1
NM_003392	WNT5A	1
NM_006328	RBM14	1
NM_004113	FGF12	1
NM_021032	FGF12	1
NM_181442	ADNP	1
NM_015339	ADNP	1
NM_000382	ALDH3A2	1
NM_001031806	ALDH3A2	1
NM_173854	SLC41A1	1
NM_025104	DBF4B	1
NM_004887	CXCL14	1
NM_001010926	HES5	1
NM_182796	MAT2B	1
NM_013283	MAT2B	1
NM_017704	ANKRD49	1
NM_199072	MDFIC	1
NM_172177	MRPL42	1
NM_172178	MRPL42	1
NM_014050	MRPL42	1
NM_145024	CES7	1
NM_032211	LOXL4	1
XM_001134423	C9orf144	1
NM_173536	GABRG1	1
NM_005819	STX6	1
NM_031418	TMEM16C	1
NM_001098798		1
NM_001098797		1
NM_001098796		1
NM_032883	TOX2	1
NM_000092	COL4A4	1
NM_001098213		1
NM_001098212		1
NM_000861	HRH1	1
NM_001098211		1
NM_207517	ADAMTSL3	1
NM_002025	AFF2	1
NM_015247	CYLD	1
NM_001042412	CYLD	1
NM_001042355	CYLD	1
NM_006054	RTN3	1
NM_201429	RTN3	1
NM_201428	RTN3	1
NM_201430	RTN3	1
NM_015053	PPFIA4	1
NM_198066	GNPNAT1	1
NM_032849	C13orf33	1
NM_014472	C10orf28	1
NM_015349	KIAA0240	1
NM_000396	CTSK	1
NM_001112800		1
NM_021097	SLC8A1	1
NM_001112801		1
NM_001112802		1
NM_022111	CLSPN	1
NM_002119	HLA-DOA	1
NM_014351	SULT4A1	1
NM_001232	CASQ2	1
NM_015316	PPP1R13B	1
NM_015275	KIAA1033	1
NM_015132	SNX13	1
NM_014035	SNX24	1
NM_000191	HMGCL	1
NM_021155	CD209	1
NM_022091	ASCC3	1
NM_000136	FANCC	1
NM_000690	ALDH2	1
NM_005759	ABI2	1
XM_001126750	ABI2	1
NM_005213	CSTA	1
NM_000110	DPYD	1
NM_005544	IRS1	1
NM_001201	BMP3	1
XM_001131068	LOC729696	1
XM_001129643	LOC731435	1
NM_133478	SLC4A5	1
XM_001132214	LOC732208	1
NM_032445	MEGF11	1
NM_017643	MBTD1	1
XM_379228	LOC401093	1
XM_944985	LOC401093	1
NM_018129	PNPO	1
NM_001039840	CHIC1	1
NM_003747	TNKS	1
NM_014757	MAML1	1
XM_001126853	MAML1	1
NM_003798	CTNNAL1	1
NM_006421	ARFGEF1	1
NM_016014	FAM108B1	1
NM_006750	SNTB2	1
NM_001080509	TSPAN11	1
XM_940107	TSPAN11	1
NM_022106	C20orf177	1
NM_000723	CACNB1	1
NM_007042	RPP14	1
NM_001098783		1
NM_001033568	RHOT1	1
NM_001033566	RHOT1	1
NM_018307	RHOT1	1
NM_148957	TNFRSF19	1
NM_005924	MEOX2	1
XM_001133646	LOC732437	1
NM_032999	GTF2I	1
NM_033000	GTF2I	1
NM_033001	GTF2I	1
NM_001518	GTF2I	1
NM_021643	TRIB2	1
NM_024090	ELOVL6	1
NM_001023567	GOLGA8B	1
NM_181077	GOLGA8A	1
NM_003618	MAP4K3	1
NM_145048	C4orf28	1
NM_000087	CNGA1	1
NM_203451	LOC400120	1
NM_144590	ANKRD22	1
NM_032626	RBBP6	1
NM_002405	MFNG	1
NM_173698	RP1-32F7.2	1
NM_001099678		1
NM_005032	PLS3	1
NM_002941	ROBO1	1
NM_133631	ROBO1	1
NM_003948	CDKL2	1
NM_173564	FLJ37538	1
NM_001008727	ZNF121	1

---

Immunostimulatory motif search results

UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).

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Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

Parameter	Spec. Score cut-off	Colour	Comment
Hit to same gene		Colour	Hits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit	≥80	Colour	Hits are very likely to cause an off-target effect
Medium scoring hit	<80¸≥40	Colour	Hits with a small chance of causing an off target effect.
Low scoring hit		Colour	Hits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-off	Colour
Match	Colour
Wobble base pairs (G-U)	Colour
Critical bases (none)	Colour
0.6 bits	Colour
0.4 bits	Colour
0.2 bits	Colour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer

For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317