Predicted Off-targets for siRNA "gggaccaagaccuaaucagac" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

10 hits were found for GACCAAGACCUAAUCAGAC (8 guide strand hits and 2 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_002168 IDH2 1248 1266 aACCAAGACCUcAUCAGgu56 4 10   false   <90%   1740
NM_001042723 RYR1 10700 10718 GACCAAGACCUcAUCAcgC40 3 11   false   <90%   15376
NM_000540 RYR1 10715 10733 GACCAAGACCUcAUCAcgC40 3 11   false   <90%   15391
NM_014483 RBMS3 450 468 GACCAgGACCUAAUCAagC10 3 10 c false   <90%   1600
NM_001003792 RBMS3 447 465 GACCAgGACCUAAUCAagC10 3 10 c false   <90%   2763
NM_001003793 RBMS3 450 468 GACCAgGACCUAAUCAagC10 3 10 c false   <90%   2817
NM_001042553 TATDN3 458 476 agaCAAGuCCUAAUCAGAC4 4 11 bc false   <90%   2383
NM_001042552 TATDN3 458 476 agaCAAGuCCUAAUCAGAC4 4 11 bc false   <90%   2386


Hits to Sense strand



AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
XR_016650 LOC643102 1624 1642 GUCUGAUgAGGUCUUGcUg9 3 8 c false   <90%   3655
XR_018984 LOC643102 1624 1642 GUCUGAUgAGGUCUUGcUg9 3 8 c false   <90%   3655


3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1619
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
XM_933050LOC3480214
XM_944169LOC3480214
NM_004798KIF3B3
NM_020844KIAA14562
NM_0010996772
NM_198074OR2C32
NM_031445AMMECR1L2
XM_209227LOC6534642
NM_199320PHF172
NM_005158ABL22
NM_007314ABL22
NM_0011001082
NM_031911C1QTNF72
NM_022755IPPK2
NM_020645NRIP32
NM_0010136622
XM_001126290LOC7279082
NM_024817THSD42
NM_080764SUHW22
NM_015299KIAA03232
NM_021977SLC22A32
NM_000168GLI32
NM_015635GAPVD12
NM_004078CSRP12
NM_014630ZNF5922
NM_020336KIAA12192
NM_198196CD962
NM_005816CD962
NM_198836ACACA2
NM_198837ACACA2
NM_198834ACACA2
NM_198838ACACA2
NM_198839ACACA2
NM_181489ZNF4452
NM_144488RGS32
NM_021106RGS32
NM_130795RGS32
NM_144489RGS32
NM_134427RGS32
NM_001080421UNC13A2
NM_005197CHES12
NM_0010854712
NM_013411AK22
NM_004588SCN2B2
NM_003629PIK3R32
NM_015090NFASC2
NM_017580ZRANB12
NM_175852TXLNA2
NM_015073SIPA1L32
NM_145808MTPN2
NM_001077637LOC1507862
NM_032144RAB6C2
NM_001106ACVR2B2
NM_020130C8orf42
NM_005156ROD12
NM_080491GAB22
NM_012296GAB22
NM_178129P2RY82
XM_938194LOC1276022
XM_059166LOC1276022
NM_022147RTP42
NM_001631ALPI2
NM_0209112
NM_080415SEPT42
NM_152757FLJ303132
NM_015042ZNF6092
NM_032682FOXP12
NM_003889NR1I22
NM_022002NR1I22
NM_033013NR1I22
NM_207577MAP62
NM_033448KRT712
NM_138972BACE12
NM_012104BACE12
NM_138973BACE12
NM_138971BACE12
NM_021615CHST62
NM_0133182
NM_013336SEC61A12
NM_015059TLN22
NM_016263FZR12
NM_144682SLFN132
NM_018085IPO92
XM_001128468NSF2
NM_006178NSF2
NM_004393DAG12
NM_006245PPP2R5D2
NM_180976PPP2R5D2
NM_180977PPP2R5D2
NM_153051MTMR32
NM_021090MTMR32
NM_153050MTMR32
NM_032932RAB11FIP42
NM_016124RHD2
NM_133334WHSC12
NM_018941CLN82
NM_015094HIC22
NM_0011004172
NM_175748C14orf1302
NM_0011050782
NM_005241EVI12
NM_0011050772
NM_001009993LOC1300742
NM_005840SPRY32
NM_004434EML12
NM_001008707EML12
XM_001125734LOC7277812
NM_001001669FLJ416032
XM_001125756LOC7277882
NM_001025233CLLU12
NM_173654C3orf641
NM_001048198SNHG3-RCC11
NM_001048197SNHG3-RCC11
NM_001048195RCC11
NM_001269RCC11
NM_001048194RCC11
NM_001048199SNHG3-RCC11
XM_210048H2BFM1
XM_936705H2BFM1
NM_001002916H2BFWT1
XM_001127257LOC7307971
XM_001127694LOC7285371
NM_153675FOXA21
NM_021784FOXA21
XM_001130258FAM69B1
NM_018176LGI21
NM_002078GOLGA41
NM_020144PAPOLB1
NM_004840ARHGEF61
NM_024969FAM130A21
NM_033515ARHGAP181
NM_007203PALM2-AKAP21
NM_147150PALM2-AKAP21
NM_001004065AKAP21
NM_139245PPM1L1
NM_006281STK31
NM_033185KRTAP3-31
NM_006948STCH1
NM_024301FKRP1
NM_001039885FKRP1
NM_152654DAND51
NM_014405CACNG41
NM_181708BCDIN3D1
NM_005376MYCL11
NM_080593HIST1H2BK1
NM_005988SPRR2A1
NM_001079669TMTC41
NM_032813TMTC41
NM_001013674C1orf1411
XM_378914KIAA04921
XM_944290KIAA04921
NM_012412H2AFV1
NM_201516H2AFV1
NM_201436H2AFV1
NM_201517H2AFV1
NM_013286RBM15B1
NM_173807C1orf1011
NM_006141DYNC1LI21
NM_032287LDOC1L1
NM_153367C10orf561
NM_004858SLC4A81
NM_006591POLD31
NM_014282HABP41
NM_001008860NIPA21
NM_001008894NIPA21
NM_001008892NIPA21
NM_030922NIPA21
NM_007006NUDT211
NM_152395NUDT161
NM_012319SLC39A61
NM_000721CACNA1E1
NM_015159KIAA02801
NM_014171CRIPT1
NM_012433SF3B11
NM_001974EMR11
NM_003409ZFP1611
NM_052854CREB3L11
NM_004220ZNF2131
NM_020630RET1
NM_138694PKHD11
NM_001001870MGC143761
NM_032895MGC143761
XM_940362LOC6459841
XM_928946LOC6459841
XM_001133973LOC7320521
NM_001002862DERL31
NM_198440DERL31
NM_001023561ZNF7491
NM_012199EIF2C11
NM_007189ABCF21
NM_002228JUN1
NM_014554SENP11
NM_032464LAT21
NM_032463LAT21
NM_014146LAT21
XM_934286LOC6470701
XM_944562LOC6470701
NM_001004329DBX21
NM_203413C17orf811
NM_001080529WIPF31
XM_939315LOC6441501
XM_935705LOC6441501
XM_291020LOC3398091
XM_936940LOC3398091
NM_000185SERPIND11
NM_139014MAPK141
NM_153263ZNF5491
NM_031485GRWD11
NM_033238PML1
NM_0010129671
NM_003966SEMA5A1
NM_002936RNASEH11
NM_032946NXF51
NM_001864COX7A11
NM_001454FOXJ11
NM_012287CENTB21
NM_020781ZNF3981
NM_170686ZNF3981
NM_001079526IKZF21
NM_016260IKZF21
NM_014220TM4SF11
NM_020796SEMA6A1
NM_024789TMEM1801
NM_198526ZNF7101
NM_015124DIP1
NM_058172ANTXR21
NM_0529271
NM_003094SNRPE1
NM_014009FOXP31
NM_017607PPP1R12C1
NM_182904P4HA31
NM_018994FBXO421
NM_0208831
NM_000965RARB1
NM_016152RARB1
NM_203412UBL4B1
XM_932289LOC6446601
XM_943717LOC6446601
NM_182826SCARA31
NM_015153PHF31
NM_001010883FAM102B1
NM_016593CYP39A11
NM_015221DNMBP1
XM_379100LOC4009581
XM_945436LOC4009581
XM_943278LOC6447271
XM_932334LOC6447271
NM_006729DIAPH21
NM_013306SNX151
NM_147777SNX151
NM_003202TCF71
NM_201632TCF71
NM_213648TCF71
NM_201634TCF71
NM_001003674C18orf11
NM_181483C18orf11
NM_181481C18orf11
NM_001003675C18orf11
NM_004338C18orf11
NM_181482C18orf11
NM_0208401
NM_000877IL1R11
NM_003956CH25H1
NM_020374C12orf41
NM_052811TRIM131
NM_213590TRIM131
NM_001007278TRIM131
NM_005798TRIM131
NM_130391PTPRD1
NM_130393PTPRD1
NM_130392PTPRD1
NM_002839PTPRD1
NM_001040712PTPRD1
NM_018976SLC38A21
NM_002040GABPA1
NM_020348CNNM11
NM_024947PHC31
NM_005614RHEB1
NM_001013640LOC3885031
NM_172364CACNA2D41
NM_001244TNFSF81
NM_014335EID11
NM_0010992941
XM_936510KIAA16441
NM_014311SMUG11
NM_001014380KATNAL11
NM_032116KATNAL11
XM_496575FLJ140821
XM_936846FLJ140821
NM_178556TRIML11
NM_005824LRRC171
NM_014614PSME41
NM_175862CD861
NM_006889CD861
NM_005472KCNE31
NM_001040875GDAP11
NM_018972GDAP11
NM_015071ARHGAP261
NM_022480KLHL251
NM_007255B4GALT71
NM_003882WISP11
NM_021954GJA31
NM_005665EVI51
NM_005060RORC1
NM_001001523RORC1
NM_021946BCORL11
NM_198483RUFY41
NM_174892CD300LB1
NM_005270GLI21
NM_001033555SPECC11
NM_001033553SPECC11
NM_173463DKFZp761B1071
NM_006685SMR3B1
NM_006091CORO2B1
NM_006359SLC9A61
NM_001042537SLC9A61
XM_943049LOC6478391
XM_932715LOC6451881
XM_928464LOC1465171
NM_033221TRIM141
NM_014788TRIM141
NM_144775SMCR81
NM_003877SOCS21
NM_001042357PTPN20B1
NM_001042358PTPN20B1
NM_001042365PTPN20B1
NM_001042361PTPN20B1
NM_001042364PTPN20B1
NM_001042360PTPN20B1
NM_001042363PTPN20B1
NM_015605PTPN20B1
NM_001042362PTPN20B1
NM_001042359PTPN20B1
NM_001042393PTPN20A1
NM_001042389PTPN20A1
NM_001042392PTPN20A1
NM_001042394PTPN20A1
NM_001042396PTPN20A1
NM_001042397PTPN20A1
NM_001042395PTPN20A1
NM_001042387PTPN20A1
NM_001042390PTPN20A1
NM_001042391PTPN20A1
NM_020804PACSIN11
NM_004741NOLC11
NM_014615KIAA01821
NM_182551LYCAT1
NM_001002257LYCAT1
NM_001077196PDE11A1
NM_001077197PDE11A1
NM_016953PDE11A1
NM_001409MEGF61
NM_015138RTF11
XM_001131019LOC7318461
XM_001131201LOC7297511
NM_022817PER21
NM_030621DICER11
NM_177438DICER11
NM_003592CUL11
NM_001017995SH3PXD2B1
NM_000450SELE1
NM_0011013681
NM_021994ZNF277P1
NM_006676USP201
NM_0011103031
NM_001008563USP201
NM_005730CTDSP21
XM_001132419SLC35F31
NM_173508SLC35F31
NM_001004304ZNF7401
NM_004167CCL151
NM_032964CCL151
NM_016373WWOX1
NM_005803FLOT11
NM_207373C10orf991
NM_001005337PKP11
NM_000299PKP11
NM_006327TIMM231
NM_016546C1RL1
NM_001001563TIMM501
NM_004251RAB9A1
NM_003391WNT21
NM_000929PLA2G51
NM_138737HEPH1
NM_014799HEPH1
NM_025248SNIP1
NM_005133RCE11
NM_001032279RCE11
NM_000672ADH61
NM_021729VPS111
NM_018431DOK51
NM_015227POFUT21
NM_133634POFUT21
NM_024408NOTCH21
XM_001133349NOTCH21
NM_198681PLEKHG51
NM_020631PLEKHG51
NM_001042664PLEKHG51
NM_001042663PLEKHG51
NM_001042665PLEKHG51
NM_001329CTBP21
NM_0010839141
NM_022802CTBP21
NM_006071PKDREJ1
NM_177963SYT121
NM_001002836ZNF7871
NM_006133DAGLA1
NM_024709C1orf1151
NM_000595LTA1
XM_001130850LOC6458221
XM_001134380LOC4419151
XM_001134064LOC4419151
NM_009589ARSD1
NM_023071SPATS21
NM_147129ALS2CL1
NM_182775ALS2CL1
NM_012315KLK91
NM_002980SCTR1
NM_001006616TSPAN171
NM_012171TSPAN171
NM_130465TSPAN171
NM_021809TGIF21
NM_144641PPM1M1
NM_022977ACSL41
NM_004458ACSL41
NM_003155STC11
NM_003396WNT9B1
NM_007053CD1601
NM_207511C9orf1391
NM_015051TXNDC41
NM_021199SQRDL1
NM_024513FYCO11
NM_022080NAPB1
NM_031886KCNA71
NM_144703LSM14B1
NM_007213PRAF21
NM_020766PCDH191
NM_0011052431
NM_138287DTX3L1
NM_017526LEPROT1
NM_015396ARMC81
NM_001039199C20orf1211
NM_024331C20orf1211
NM_004742MAGI11
NM_005076CNTN21
NM_001033518WIPI21
NM_001033519WIPI21
NM_015610WIPI21
NM_001033520WIPI21
NM_016003WIPI21
NM_012256ZNF2121
NM_138731MIPOL11
NM_194293CMYA11
NM_0010853771
NM_002387MCC1
XM_944654LOC6487161
XM_935966LOC6417981
XM_935369LOC6463291
NM_001040157KIAA17121
NM_017577GRAMD1C1
NM_138400NOM11
NM_003741CHRD1
NM_001761CCNF1
NM_017585SLC2A61
NM_006454MXD41
NM_003632CNTNAP11
NM_016433GLTP1
NM_025221KCNIP41
NM_001035003KCNIP41
NM_001035004KCNIP41
NM_147183KCNIP41
NM_147182KCNIP41
NM_147181KCNIP41
XM_496355LOC4405771
XM_001130897LOC4405771
NM_013269CLEC2D1
NM_001004419CLEC2D1
NM_001054SULT1A21
NM_177528SULT1A21
NM_005717ARPC51
NM_001987ETV61
NM_014718CLSTN31
NM_170740ALDH5A11
NM_001080ALDH5A11
NM_002073GNAZ1
NM_014732KIAA05131
XM_937862LOC6449621
NM_153838GPR1151
NM_006013RPL101
NM_018667SMPD31
NM_0152951
NM_014228SLC6A71
NM_178582HM131
NM_0011001641
NM_0011001661
NM_014721PHACTR21
NM_0011001651
NM_178422PAQR71
NM_182508C13orf301
NM_006895HNMT1
NM_002227JAK11
NM_004035ACOX11
NM_007292ACOX11
NM_002417MKI671
NM_032296FLYWCH11
NM_020718USP311
NM_021905GABBR11
NM_005491CXorf61
NM_018235CNDP21
NM_016138COQ71
NM_147175HS6ST21
NM_001077188HS6ST21
NM_175061JAZF11
NM_001001974PLEKHA11
NM_021622PLEKHA11
NM_000163GHR1
NM_006073TRDN1
NM_207295MBNL11
NM_207293MBNL11
NM_207297MBNL11
NM_207296MBNL11
NM_207294MBNL11
NM_021038MBNL11
NM_207292MBNL11
NM_020809ARHGAP201
NM_024596MCPH11
NM_000510FSHB1
NM_001018080FSHB1
NM_021004DHRS41
NM_198083DHRS4L21
XM_001133080LOC7313561
XM_001133093LOC7313561
XM_001133076LOC7313561
XM_001133109LOC7313561
XM_001133116LOC7313561
NM_001082488LOC7286351
XM_001133105LOC7313561
XM_001133065LOC7313561
XM_001131304LOC7286351
XM_001133102LOC7313561
NM_014586HUNK1
NM_018444PPM2C1
NM_014319LEMD31
NM_153481IL17RE1
NM_153483IL17RE1
NM_153480IL17RE1
NM_025136OPA31
NM_012342BAMBI1
NM_021947SRR1
NM_031479INHBE1
NM_000226KRT91
NM_004321KIF1A1
NM_001031741NEK101
NM_001001938C9orf471
NM_024949WWC21
NM_020431TMEM63C1
NM_001489NR6A11
NM_033334NR6A11
NM_006505PVR1
NM_032294CAMKK11
NM_172206CAMKK11
NM_007101SARDH1
NM_153456HS6ST31
NM_022351EFCBP11
NM_004983KCNJ91
NM_194286KIAA18531
NM_207334FAM43B1
NM_016023OTUD6B1
NM_138636TLR81
NM_017790RGS31
NM_0011096891
NM_021061ZNF2501
NM_017693BIVM1
NM_016346NR2E31
NM_144579SFXN51
NM_198896RAB6A1
NM_002869RAB6A1
NM_032683FKSG241
NM_033254BOC1
NM_020347LZTFL11
NM_0010994391
NM_015719COL5A31
NM_006322TUBGCP31
NM_006937SUMO21
NM_001005849SUMO21
XM_001127385LOC7307761
XM_001128769LOC7288251
XM_001131540LOC6524891
XM_941950LOC6524891
XM_001126213LOC6524891
NM_001002255SUMO41
XM_931553LOC6434491
XM_945026LOC6434491
NM_004329BMPR1A1
NM_000813GABRB21
NM_021911GABRB21
NM_013255MKLN11
NM_001001549GRB101
NM_001001555GRB101
NM_001001550GRB101
NM_005311GRB101
NM_000457HNF4A1
NM_178849HNF4A1
NM_198098AQP11
NM_198270NHS1
XM_001134060NHS1
NM_175881ODF3L11
NM_0204591
NM_003129SQLE1
NM_000025ADRB31
NM_173598KSR21
NM_0153021
NM_0011003901
NM_152558IQCE1
XM_001130903LOC7318071
XM_001127077LOC7282871
NM_006407ARL6IP51
NM_001682ATP2B11
NM_001001323ATP2B11
NM_014613UBXD81
NM_032446MEGF101
NM_152673MUC201
NM_0010985161
NM_020715PLEKHH11
NM_032047B3GNT51
NM_003215TEC1
NM_014587SOX81
NM_170774RASSF21
NM_014737RASSF21
NM_178826TMEM16D1
NM_144711KLHL231
NM_020375C12orf51
NM_001039349EFEMP11
NM_004105EFEMP11
NM_001039348EFEMP11
NM_013328PYCR21
NM_017956TRMT121
NM_002254KIF3C1
NM_000228LAMB31
NM_001017402LAMB31
NM_0010129941
NM_001040152PEG101
NM_201525GPR561
NM_201524GPR561
NM_005682GPR561
NM_138477CDAN11
XM_001129302CDAN11
NM_005026PIK3CD1
NM_033410ZNF7641
NM_016513ICK1
NM_014920ICK1
NM_031481SLC25A181
NM_000831GRIK31
NM_004952EFNA31
NM_152517TTC30B1
NM_0151231
NM_017563IL17RD1
NM_001080973IL17RD1
NM_006180NTRK21
NM_001018064NTRK21
NM_138450ARL111
NM_015190DNAJC91
NM_201633TCF71
NM_0011102131
NM_005042PRH21
NM_001804CDX11
NM_006371CRTAP1
XM_379324LOC3401131
XM_943214LOC3401131
NM_001010867C1orf691
NM_014862ARNT21
NM_206925CA121
NM_001218CA121
NM_004863SPTLC21
NM_032429LZTS21
NM_005740DNAL41
NM_201999ELF21
NM_006874ELF21
NM_006905PSG11
NM_032966BLR11
NM_001716BLR11
NM_017415KLHL31
NM_052875VPS26B1
NM_013267GLS21
NM_018287ARHGAP121
NM_002484NUBP11
NM_181774SLC36A31
NM_052965C1orf191
NM_0011050791
NM_170692RASAL21
NM_004841RASAL21
NM_001037954DIXDC11
NM_033425DIXDC11
NM_002997SDC11
NM_001006946SDC11
NM_017655GIPC21
NM_003692TMEFF11
NM_012392PEF11
NM_004809STOML11
NM_016817OAS21
XM_370758LOC3879781
XM_940323LOC3879781
NM_198149TMEM581
NM_0146921
XM_001128664LOC7282031
NM_012333MYCBP1
NM_000424KRT51
NM_005228EGFR1
NM_018194HHAT1
NM_018306TMEM401
XM_929433LOC6440061
XM_939111LOC6500201
NM_002938RNF41
XM_001128799MAP3K21
NM_014873LPGAT11
NM_002640SERPINB81
NM_198833SERPINB81
NM_0209101
NM_001077352RBM231
NM_018107RBM231
NM_001077351RBM231
NM_018393TCP11L11
XM_926336LOC6424511
XM_942222LOC6424511
NM_133261GIPC31
NM_018518MCM101
NM_182751MCM101
NM_1735951
NM_145013C11orf451
NM_153487MDGA11
NM_144779FXYD51
NM_014164FXYD51
NM_007050PTPRT1
NM_133170PTPRT1
NM_000744CHRNA41
NM_0153721
NM_018992KCTD51
NM_014048MKL21
NM_004644AP3B21
NM_001039479KIAA03171
NM_024640YRDC1
NM_178502DTX31
NM_001903CTNNA11
NM_144639UROC11
NM_003885CDK5R11
NM_003216TEF1
NM_005811GDF111
NM_177999ASB61
NM_017873ASB61
NM_020312COQ91
NM_0011056691
XM_371655LOC3891371
NM_031905ARMC101
NM_182500C2orf501
NM_003653COPS31
NM_0011045901
NM_0011045891
NM_0011045871
NM_152270SLFN111
NM_0011045881
NM_024963FBXL181
NM_015557CHD51
NM_002334LRP41
NM_001896CSNK2A21
NM_015720PODXL21
NM_080621SAMD101
NM_014694ADAMTSL21
NM_021168RAB40C1
NM_130469JDP21
NM_001049SSTR11
NM_004339PTTG1IP1
NM_003985TNK11
NM_152375KLHDC7A1
NM_007061CDC42EP11
NM_152243CDC42EP11
NM_198186ASTN21
NM_198187ASTN21
NM_014010ASTN21
NM_198188ASTN21
NM_177536SULT1A11
NM_177534SULT1A11
NM_177530SULT1A11
NM_001055SULT1A11
NM_177529SULT1A11
XM_001128273LOC7287191
NM_012405ICMT1
NM_022840METTL41
NM_018452C6orf351
NM_145685BRF11
NM_001519BRF11
NM_022377ICAM41
NM_001933DLST1
NM_003791MBTPS11
NM_004738VAPB1
XM_943589LOC6479461
NM_001081472SPATA11
NM_032818C9orf1001
NM_133370YTHDC11
NM_001031732YTHDC11
NM_001860SLC31A21
NM_018207TRIM621
NM_001001420SMAD51
NM_001001419SMAD51
NM_005903SMAD51
NM_000369TSHR1
NM_033138CALD11
NM_033139CALD11
NM_004342CALD11
NM_033157CALD11
NM_033140CALD11
NM_001012508SPRN1
NM_033200TMEM112B1
XM_001127604NFATC2IP1
NM_032815NFATC2IP1
XM_926338LOC6429561
XM_938166LOC6429561
XM_001132811LOC7291631
XM_001134012LOC7320311
XM_001127657LOC7310431
XM_001128089LOC7286411
NM_001444FABP51
XM_937508LOC3879341
XM_370729LOC3879341
NM_181521CMTM41
NM_181704BAGE41
NM_032289PSD21
XM_377476MGC573461
NM_033087ALG21
NM_182484BAGE51
NM_001187BAGE1
NM_0011132391
NM_022740HIPK21
XM_379273FLJ141861
XM_001130364LOC7284171
XM_001130184LOC7308431
NM_003173SUV39H11
NM_000217KCNA11
NM_0011112831
NM_000618IGF11
NM_0011112841
NM_001001936AFAP1L21
NM_032550AFAP1L21
XM_934649C1orf341
XM_945958C1orf341
NM_003445ZNF1551
NM_198089ZNF1551
NM_015200SCC-1121
NM_0011003991
NM_001494GDI21
NM_003901SGPL11
NM_003281TNNI11
NM_033419PERLD11
NM_000286PEX121
NM_024627C22orf291
NM_177538CYP20A11
NM_0011055761
NM_153697ANKRD441
XM_378661C17orf511
XM_944416C17orf511
NM_130476MADD1
NM_130472MADD1
NM_130470MADD1
NM_130474MADD1
NM_130471MADD1
NM_003682MADD1
NM_130475MADD1
NM_130473MADD1
NM_197949CLEC7A1
NM_197950CLEC7A1
NM_022570CLEC7A1
NM_197948CLEC7A1
NM_197947CLEC7A1
NM_017706WDR551
NM_182526C14orf831
NM_022719DGCR141
NM_024556FAM118B1
NM_021198CTDSP11
NM_001042475C6orf2041
NM_130762MADCAM11
NM_130760MADCAM11
NM_003023SH3BP21
NM_000674ADORA11
NM_001048230ADORA11
NM_033131WNT3A1
NM_019035PCDH181
NM_016221DCTN41
NM_005041PRF11
NM_001083116PRF11
NM_0011127361
NM_207404ZNF6621
NM_020354ENTPD71
NM_198859PRICKLE21
NM_001018111PODXL1
NM_005397PODXL1
NM_005959MTNR1B1
XM_934270LOC6470651
XM_943487LOC6470651
NM_001080393GLT8D41
XM_001133467PKD1L31
XM_001134223PKD1L31
NM_003317TITF11
NM_001079668TITF11
NM_018977NLGN31
NM_203288RP91
NM_153756FNDC51
NM_032892FRMD51
NM_014953DIS31
NM_006237POU4F11
NM_203284RBPJ1
NM_203283RBPJ1
NM_015874RBPJ1
NM_005349RBPJ1
NM_020960GPR1071
NM_152496MANEAL1
NM_001031740MANEAL1
NM_024492LPAL21
NM_012096APPL11
NM_005312RAPGEF11
NM_198679RAPGEF11
NM_001039615LOC4400531
XM_001130086LOC7289571
NM_001024847TGFBR21
NM_003242TGFBR21
NM_001035521GTF3C21
NM_001521GTF3C21
NM_006670TPBG1
NM_2073061
NM_001082534CA101
NM_020178CA101
NM_001082533CA101
NM_030817APOLD11
NM_171982TRIM351
NM_001039905FLJ385961
NM_001025100MBP1
NM_152547BTNL91
NM_033089ZCCHC31
NM_005852CHD31
NM_001005271CHD31
NM_001005273CHD31
NM_030634ZNF4361
NM_001077195ZNF4361
NM_153214FLJ374401
NM_003099SNX11
NM_152826SNX11
NM_148955SNX11
NM_002507NGFR1
NM_181709FAM101A1
NM_0010997371
NM_032332MORG11
NM_001040445ASB11
NM_152406AFAP1L11
NM_152901PYDC11
NM_016606REEP21
NM_016829OGG11
NM_016827OGG11
NM_016828OGG11
NM_006380APPBP21
NM_020975RET1
NM_015040PIP5K31
NM_0010988161
NM_178857RP1L11
NM_018666SAGE11
XM_942822LOC6466261
XM_933781LOC6466261
NM_017770ELOVL21
NM_012244SLC7A81
NM_182728SLC7A81
NM_152443RDH121
NM_004293GDA1
NM_198392TCF211
XM_941808LOC3998881
XM_374880LOC3998881
NM_001031700C4orf181
NM_016613C4orf181
NM_033025SYDE11
NM_138813ATP8B31
NM_024875SYNPO2L1
NM_152744SDK11
NM_005140CNGA21
NM_001837CCR31
NM_178329CCR31
NM_015481ZNF3851
NM_000797DRD41
NM_015540RPAP11
NM_002398MEIS11
NM_022836DCLRE1B1
NM_024742ARMC51
NM_052898XKR41
NM_001546ID41
NM_001080439HSF51
XM_939614HSF51
NM_024306FA2H1
NM_003006SELPLG1
NM_138415PHF21B1
NM_053046EGLN21
NM_080732EGLN21
NM_001003396TPD52L11
NM_001003397TPD52L11
NM_001017440CALN11
NM_031468CALN11
NM_0209411
NM_033631LUZP11
XM_001128311LOC7314491
XM_001129750LOC7289991
NM_001001389CD441
NM_001001390CD441
NM_001001391CD441
NM_001001392CD441
NM_000610CD441
NM_004807HS6ST11
NM_001014797KCNMA11
XM_001132928LOC7289691
NM_004386NCAN1
NM_001042590C9orf1271
NM_001042589C9orf1271
NM_152308C16orf751
NM_032656DHX371
NM_152550SH3RF21
NM_020404CD2481
XM_001133783LOC7295821
XM_001131644LOC7309491
NM_015247CYLD1
NM_001042412CYLD1
NM_001042355CYLD1
NM_033550TP53RK1
NM_000991RPL281
NM_012288TRAM21
NM_002740PRKCI1
NM_005220DLX31
NM_025074FRAS11
NM_052932TMEM1231
NM_018655LENEP1
NM_001005210LRRC551
NM_201437TCEA11
NM_006756TCEA11
NM_015076CDC2L61
NM_032228MLSTD21
NM_031904FKSG441
NM_033224PURB1
NM_002569FURIN1
NM_003458BSN1
NM_152785GCET21
NM_001008756GCET21
NM_005761PLXNC11
NM_080669SLC46A11
NM_001012755MCART61
NM_021635PBOV11
NM_020778ALPK31
XM_001130955LOC7303471
XM_001127355LOC7283771
NM_033100PCDH211
NM_001080530LOC920171
NM_080836STK351
NM_012193FZD41
NM_003025SH3GL11
NM_001007024GOSR11
NM_001007025GOSR11
NM_004871GOSR11
NM_000322PRPH21
XM_927413LOC6434121
XM_937493LOC6479691
NM_016081PALLD1
NM_021033RAP2A1
NM_0010986721
XM_943029LOC3890431
XM_374012LOC3890431
NM_014910ZNF5071
NM_004594SLC9A51
NM_013364PNMA31
NM_014951ZNF3651
NM_032855HSH2D1
NM_183337RGS111
NM_003834RGS111
XM_001125737LOC7302751
NM_032827ATOH81
NM_001011722ARHGEF10L1
NM_018125ARHGEF10L1
NM_152726EFHA11
NM_000084CLCN51
NM_001031702SEMA5B1
NM_020187C3orf371
NM_001006109C3orf371
XM_945019LOC6434411
XM_933124LOC6434411
NM_053055THEM41
NM_012125CHRM51
NM_152511DUSP181
NM_007351MMRN11
NM_003468FZD51
NM_145867LTC4S1
NM_182832PLAC41
NM_030907C1orf891
NM_020964KIAA16321
NM_006841SLC38A31
NM_001032396PJA11
NM_145119PJA11
NM_022368PJA11
NM_002086GRB21
NM_203506GRB21
NM_152222TNFRSF19L1
NM_032871TNFRSF19L1
NM_033141MAP3K91
NM_198686RAB151
NM_133477SYNPO21
XM_942776SYNPO21
XM_936336SYNPO21
NM_012394PFDN21
NM_145102ZKSCAN51
NM_014569ZKSCAN51
NM_201397GPX11
NM_000581GPX11
NM_006374STK251
NM_006650CPLX21
NM_001008220CPLX21
XM_940667SDC31
NM_000417IL2RA1
XM_927470LOC6442971
XM_001133301LOC7290081
NM_032177RNUXA1
NM_002562P2RX71
NM_021967SERF1A1
XM_001130863LOC7284921
NM_022978SERF1B1
XM_001130858LOC7284921
NM_003831RIOK31
NM_020914RNF2131
NM_001033723ZNF7041
NM_022075LASS21
NM_181746LASS21
NM_002736PRKAR2B1
NM_001001664LOC3397451
NM_018660ZNF3951
NM_022774C1orf1761
NM_017637BNC21
NM_001029885MGC103341
NM_057179TWIST21
NM_006722MITF1
NM_000248MITF1
NM_198158MITF1
NM_198177MITF1
NM_198178MITF1
NM_198159MITF1
NM_005056JARID1A1
NM_001042603JARID1A1
NM_173691C9orf751
XM_925864LOC6423251
XM_929030LOC1615271
XM_933066LOC6436961
XM_001129399LOC6423461
XM_928707LOC6423461
XM_925879LOC6423461
XM_001130526LOC7286361
XM_001130555LOC7286361
XM_001130543LOC7286361
XM_001130536LOC7286361
NM_130443DPP31
NM_005700DPP31
NM_018157RIC8B1
NM_0150161
NM_002214ITGB81
NM_022821ELOVL11
NM_001174ARHGAP61
NM_018984SSH11
NM_006691XLKD11
NM_203472SELS1
NM_017846TRSPAP11
NM_203329CD591
NM_203331CD591
NM_203330CD591
NM_000611CD591
NM_021823PPCDC1
NM_001949E2F31
NM_001007156NTRK31
NM_005933MLL1
NM_018332DDX19A1
NM_018658KCNJ161
NM_170742KCNJ161
NM_170741KCNJ161
NM_001008539SLC7A21
NM_003046SLC7A21
NM_003627SLC43A11
NM_006898HOXD31
NM_171998RAB39B1
NM_006145DNAJB11
NM_145239PRRT21
NM_006349ZNHIT11
NM_021806FAM3A1
NM_152743C7orf271
NM_001008393LOC2017251
NM_032595PPP1R9B1
NM_003214TEAD31
NM_031310PLVAP1
NM_001014989LAT1
NM_001014987LAT1
NM_001014988LAT1
NM_014387LAT1
NM_152462AMAC11
NM_178553C2orf531
NM_032765TRIM521
NM_003379VIL21
NM_0011110771
NM_014800ELMO11
NM_001039459ELMO11
NM_130442ELMO11
NM_199181C20orf1171
NM_003489NRIP11
NM_001011547SLC5A91
NM_182557BCL9L1
NM_018385LSG11
NM_003028SHB1
NM_002096GTF2F11
NM_015393DKFZP564O08231
NM_015683ARRDC21
NM_001025604ARRDC21
NM_000683ADRA2C1
NM_007176C14orf11
NM_014337PPIL21
NM_148176PPIL21
NM_148175PPIL21
NM_021167GATAD11
NM_147180PPP3R21
NM_032424KIAA18261
NM_199487C20orf441
NM_018244C20orf441
NM_015425POLR1A1
NM_001034025ERP291
NM_018113LMBR1L1
NM_203327SLC23A21
NM_005116SLC23A21
NM_005781TNK21
NM_001010938TNK21
NM_001039667ANGPTL41
NM_139314ANGPTL41
NM_032373PCGF51
NM_014938MLXIP1
NM_014767SPOCK21
NM_212533ABCA21
NM_001606ABCA21
NM_005729PPIF1
XM_940903ZC3H51
NM_001080419UNK1
NM_006312NCOR21
NM_001077261NCOR21
NM_152341PAQR41
NM_014388C1orf1071
NM_018245OGDHL1
NM_002522NPTX11
NM_015725RDH81
NM_001035507AGBL51
NM_000758CSF21
NM_020954KIAA16181
NM_030927TSPAN141
NM_004444EPHB41
XM_001131911LOC6459041
XM_938424LOC6459041
XM_928876LOC6459041
NM_001759CCND21
NM_022780RMND5A1
NM_024819DCAKD1
NM_207406CCDC41
NM_001009992ZNF6481
NM_007331WHSC11
NM_004612TGFBR11
NM_024016HOXB81
NM_001421ELF41
NM_0010988111
NM_015569DNM31
NM_032458PHF61
NM_001015877PHF61
NM_000785CYP27B11
NM_024577SH3TC21
NM_020313CIAPIN11
NM_021204ENOPH11
XM_001126326AGRIN1
NM_198576AGRN1
NM_006643SDCCAG31
NM_001039708SDCCAG31
NM_001039707SDCCAG31
NM_004758BZRAP11
NM_003742ABCB111
NM_020764CASKIN11
NM_199183TESSP51
NM_020184CNNM41
NM_144969ZDHHC151
NM_021137TNFAIP11
NM_207170SYF21
NM_015484SYF21
NM_002479MYOG1
NM_020870SH3RF11
NM_016577RAB6B1
NM_000136FANCC1
NM_016605FAM53C1
NM_017656ZNF5621
NM_003503CDC71
NM_002033FUT41
NM_015328KIAA08281
XM_001133548LOC7315801
XM_001133560LOC7294261
NM_0207251
NM_001013622FAM53A1
NM_014047C19orf531
NM_001831CLU1
NM_203339CLU1
NM_000832GRIN11
NM_007327GRIN11
NM_021569GRIN11
NM_006690MMP241
NM_138493C6orf1291
NM_003483HMGA21
NM_015170SULF11
NM_005663WHSC21
NM_033348KCNK71
NM_033455KCNK71
NM_005714KCNK71
NM_015270ADCY61
NM_020983ADCY61
NM_152349KRT222P1
NM_019089HES21
NM_001024680LOC5542511
NM_030961TRIM561
NM_139321ATRN1
NM_016206VGLL31
NM_207348SLC25A341
NM_016599MYOZ21
NM_080872UNC5D1
NM_002221ITPKB1
NM_002729HHEX1
NM_152765C8orf461
NM_0011016761
NM_002737PRKCA1
NM_000623BDKRB21
NM_024516C16orf531
NM_004985KRAS1
NM_033360KRAS1
XM_001128450LOC7282291
XM_001131298LOC7309901
XM_001128423LOC7282291
XM_928466LOC6454261
XM_001128399LOC7282291
XM_001131270LOC7309901
NM_006628ARPP-191
NM_022720DGCR81
NM_006995BTN2A21
NM_181531BTN2A21
NM_007049BTN2A11
NM_078476BTN2A11
NM_006750SNTB21
NM_016530RAB8B1
NM_002990CCL221
NM_015002FBXO211
NM_033624FBXO211
NM_017933PID11
NM_0011008181
NM_005721ACTR31
NM_023930KCTD141
NM_054022GOSR21
NM_004287GOSR21
NM_182916TRNT11
NM_007007CPSF61
NM_001030060SAMD51
NM_004598SPOCK11
NM_001012418LOC3401561
NM_020792AADACL11
NM_017510TMED91
NM_006920SCN1A1
NM_021822APOBEC3G1
NM_001029859KCTD211
NM_007137ZNF811
XM_928022LOC6449351
XM_001130944LOC6449351
NM_016479SCOTIN1
NM_030622CYP2S11
NM_014901RNF441
NM_006203PDE4D1
NM_0011046311
NM_001025079CD471
NM_001777CD471
NM_198793CD471
NM_016083CNR11
NM_033181CNR11
NM_181655C17orf581
NM_181656C17orf581
NM_024749VASH21
NM_003714STC21
NM_144781PDCD21
NM_003873NRP11
NM_014851KLHL211
NM_014634PPM1F1
NM_006624ZMYND111
NM_0010992891
NM_207445FLJ395311
NM_025164KIAA09991
NM_020139BDH21
NM_001012427FOXP41
NM_138457FOXP41
NM_001012426FOXP41
NM_006951TAF51
NM_153262SYT141
NM_052909KIAA19091
NM_198719PTGER31
NM_001020821MYADM1
NM_001020818MYADM1
NM_001020819MYADM1
NM_138373MYADM1
NM_001020820MYADM1
NM_005169PHOX2A1
NM_022469GREM21
NM_002725PRELP1
NM_201348PRELP1
NM_001004313LOC3883351
NM_005772RCL11
NM_004302ACVR1B1
NM_052884SIGLEC111
NM_020853KIAA14671
NM_006187OAS31
NM_002346LY6E1
NM_017712PGPEP11
NM_003043SLC6A61
NM_014734KIAA02471
NM_182511CBLN21
NM_003636KCNAB21
NM_172130KCNAB21
NM_013402FADS11
NM_002419MAP3K111
NM_001908CTSB1
NM_147781CTSB1
NM_147783CTSB1
NM_147780CTSB1
NM_147782CTSB1
NM_0010988131
NM_0151461
NM_0010988121
NM_002523NPTX21
XM_944838LOC2857331
XM_379432LOC2857331
NM_173551ANKS61
XM_001130956ANKS61
NM_017709FAM46C1
XM_941162LOC4009501
XM_376049LOC4009501
NM_024918DSN11
NM_153708RTP11
NM_003417ZNF2641
NM_014864FAM20B1
NM_145256LRRC251
NM_003042SLC6A11
NM_172037RDH101
XM_295865C10orf1121
XM_939359LOC6502691
NM_175733SYT91
NM_001039960SLC4A81
NM_001040613TMEM701
NM_017866TMEM701
NM_001527HDAC21
NM_015394ZNF101
NM_001003656PPP2R2D1
NM_018461PPP2R2D1
NM_018702ADARB21
NM_002881RALB1
NM_022458LMBR11
NM_198562C3orf621
NM_014035SNX241
NM_175921LOC2856361
NM_023002HAPLN41
NM_015316PPP1R13B1
NM_000748CHRNB21
NM_033044MACF11
NM_012090MACF11
NM_153645NUP501
NM_007172NUP501
NM_001043SLC6A21
NM_020782KLHDC51
NM_198471ANKRD471
NM_014155ZBTB441
NM_005168RND31
NM_033394TANC11
NM_002460IRF41
NM_032510PARD6G1
XM_001129334PARD6G1
NM_032638GATA21
NM_012120CD2AP1
NM_004309ARHGDIA1
NM_015341NCAPH1
NM_031910C1QTNF61
NM_182486C1QTNF61
NM_014956CEP1641
NM_000259MYO5A1
NM_005338HIP11
XM_001131308LOC7309611
NM_006785MALT11
NM_173844MALT11
NM_016173HEMK11
XM_931612LOC6435291
XM_943256LOC6435291
XM_001130189LOC7315981
XM_001129850LOC7292911
NM_001080428ODZ21
XM_945786ODZ21
XM_945788ODZ21
XM_942208ODZ21
XM_931456ODZ21
NM_004055CAPN51
NM_001013625C1orf1921
NM_004618TOP3A1
NM_001040146CTF81
NM_001039690CTF81
NM_001040144CTF81
NM_020120UGCGL11
NM_001025777UGCGL11
NM_016734PAX51
NM_003137SRPK11
NM_000742CHRNA21
NM_003863DPM21
NM_001039570KREMEN11
NM_001039571KREMEN11
NM_138717PPT21
NM_005155PPT21
NM_001040020FAM3C1
NM_014888FAM3C1
XM_001131779LOC7309191
NM_017772TBC1D22B1
NM_001039580MAP91
NM_006139CD281
NM_153365TAPT11
NM_015986CRLF31
NM_013375ABT11
NM_002581PAPPA1
NM_019058DDIT41
NM_017785CCDC991
NM_001001524TM6SF21
NM_001042493C6orf1621
NM_020425C6orf1621
NM_016441CRIM11
NM_014772KIAA04271
NM_021629GNB41
NM_001042467MLPH1
NM_024101MLPH1
NM_002833PTPN91
XM_001128975PTPN91
XM_941994TMEM132C1
XM_044062TMEM132C1
NM_033210ZNF5021
XM_001126151LOC7278581
XM_001130844LOC7287641
NM_018279TMEM191
NM_003234TFRC1
NM_006460HEXIM11
NM_006408AGR21
XM_944366LOC3752951
XM_374020LOC3752951
NM_005934MLLT11
NM_0195891
NM_144652LETM21
NM_178010SOX51
NM_006940SOX51
NM_152989SOX51
NM_001077490GNAS1
NM_016592GNAS1
NM_018121C10orf61
NM_005507CFL11
NM_006529GLRA31
NM_001042543GLRA31
NM_1449931
NM_003162STRN1
NM_0152761
NM_177925H2AFJ1
NM_0146871
NM_1735691
NM_173683XKR61
XM_001130815LOC6478591
XM_001127102LOC6478591
XM_936921LOC6478591
NM_001042492NF11
NM_000267NF11
NM_198563TMEM1101
NM_015116LRCH11
NM_052905FMNL21
NM_152699SENP51
NM_018059FLJ103241
NM_0190041
NM_001083924C1orf1161
NM_023938C1orf1161
NM_021794ADAM301
XM_042978FRMPD31
XM_937007FRMPD31
NM_002401MAP3K31
NM_203351MAP3K31
NM_173570ZDHHC231
NM_006502POLH1
NM_015161ARL6IP11
NM_025015HSPA12A1
NM_144997FLCN1
NM_006912RIT11
NM_001364DLG21
NM_018293ZNF6541
XM_001126706ZNF6541
NM_181844BCL6B1
NM_024665TBL1XR11
NM_031476CRISPLD21
XM_928199LOC4005811
XM_001131007LOC7296781
XM_001127177LOC7307801
NM_000104CYP1B11
NM_203447DOCK81
NM_003485GPR681
NM_016033FAM82B1
NM_001011708GTPBP91
NM_013341GTPBP91
NM_206853QKI1
NM_206854QKI1
NM_206855QKI1
NM_005819STX61
NM_0216231
XM_942692MGC51391
NM_001080533MGC51391
NM_020845PITPNM21
NM_138618RHCE1
NM_138617RHCE1
NM_138368DKFZp761E1981

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317