VIRsiRNAdb

SpecificityServer - An siRNA design program for determining siRNA specificity
Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

26 hits were found for GGCUCUAGGAUCAGAAAGA (13 guide strand hits and 13 sense strand hits.)

Hits to Guide strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_007347

AP4E1

2346

2364

u

G

g

U

C

U

A

G

G

A

U

C

A

G

A

A

A

G

u

73

3

15

bc

false

<90%

6682

NM_005839

SRRM1

3499

3517

a

G

C

U

C

U

A

G

G

A

U

g

A

G

A

c

A

G

A

38

3

10

false

<90%

3952

XM_001125704

LOC727778

553

571

u

G

C

U

u

U

A

G

G

A

U

C

u

G

A

A

A

G

A

36

3

7

false

<90%

2506

XM_001125757

LOC727778

553

571

u

G

C

U

u

U

A

G

G

A

U

C

u

G

A

A

A

G

A

36

3

7

false

<90%

4271

XM_001125727

LOC727778

553

571

u

G

C

U

u

U

A

G

G

A

U

C

u

G

A

A

A

G

A

36

3

7

false

<90%

4332

NM_016426

GTSE1

2078

2096

G

G

C

U

g

U

A

G

G

A

U

C

u

G

A

A

A

G

c

33

3

7

false

<90%

4493

NM_001017370

LOC387921

1268

1286

a

G

a

U

C

U

A

G

u

A

U

C

A

G

A

A

A

G

A

18

3

10

bc

false

<90%

3371

NM_001012754

LOC387921

1469

1487

a

G

a

U

C

U

A

G

u

A

U

C

A

G

A

A

A

G

A

18

3

10

bc

false

<90%

3572

NM_018166

C1orf78

130

148

G

G

C

U

u

U

A

G

G

A

U

C

A

G

A

g

A

G

c

17

3

10

c

false

<90%

1054

XM_932285

LOC644652

85

103

G

G

C

U

C

U

A

G

G

A

a

C

A

G

A

g

A

G

c

7

3

10

c

false

<90%

1494

NM_014010

ASTN2

2737

2755

G

G

C

U

C

c

A

G

u

A

U

C

A

G

A

A

A

G

A

-23

2

10

bc

false

<90%

4606

NM_198186

ASTN2

2878

2896

G

G

C

U

C

c

A

G

u

A

U

C

A

G

A

A

A

G

A

-23

2

10

bc

false

<90%

4756

NM_198187

ASTN2

2890

2908

G

G

C

U

C

c

A

G

u

A

U

C

A

G

A

A

A

G

A

-23

2

10

bc

false

<90%

4768

Hits to Sense strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_173059

ZAN

11

29

g

a

U

U

U

C

U

G

A

U

C

C

U

u

G

A

G

C

u

62

4

11

c

false

<90%

8416

NM_003386

ZAN

11

29

g

a

U

U

U

C

U

G

A

U

C

C

U

u

G

A

G

C

u

62

4

11

c

false

<90%

8689

NM_022783

DEPDC6

2038

2056

U

C

U

U

U

C

U

G

A

U

C

C

U

A

a

A

u

C

a

46

3

14

c

false

<90%

2187

NM_001017440

CALN1

1615

1633

g

C

U

U

U

C

U

G

u

U

C

C

U

A

G

A

G

C

C

37

2

10

bc

false

<90%

5802

NM_031468

CALN1

1796

1814

g

C

U

U

U

C

U

G

u

U

C

C

U

A

G

A

G

C

C

37

2

10

bc

false

<90%

5983

NM_024676

C1orf113

2305

2323

g

C

U

c

U

C

U

G

A

U

C

C

U

A

a

A

G

C

C

36

3

10

c

false

<90%

3182

NM_016081

PALLD

3113

3131

a

C

U

c

U

C

U

G

A

U

C

a

U

A

G

A

G

C

C

27

3

7

false

<90%

5809

NM_031453

FAM107B

3135

3153

c

a

U

U

U

C

U

G

u

U

C

C

U

A

G

A

G

C

u

21

4

9

bc

false

<90%

3785

NM_178031

TMEM132A

434

452

c

C

U

U

U

C

U

G

c

U

C

C

U

A

c

A

G

C

C

13

3

7

c

false

<90%

3517

NM_017870

TMEM132A

434

452

c

C

U

U

U

C

U

G

c

U

C

C

U

A

c

A

G

C

C

13

3

7

c

false

<90%

3520

NM_015690

STK36

477

495

U

C

U

U

U

C

a

G

A

U

C

C

U

A

G

A

a

g

a

2

4

9

c

false

<90%

4887

NM_014384

ACAD8

1693

1711

U

C

U

U

c

C

U

G

A

U

u

C

U

A

G

A

G

C

a

-17

3

7

c

false

<90%

2216

NM_018370

DRAM

2321

2339

U

C

U

U

U

C

a

a

A

U

C

C

U

A

G

A

G

C

a

-33

3

10

bc

false

<90%

3553

---

3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1079
View matched accessions

3 prime seed match details

Accession	Gene name	Hits to this gene
XM_001132119	LOC257407	3
XM_001129456	LOC257407	3
NM_006047	RBM12	3
NM_152838	RBM12	3
NM_033100	PCDH21	3
NM_175736	FMNL3	3
NM_198900	FMNL3	3
XM_375929	LOC400856	2
NM_015074	KIF1B	2
NM_014731	ProSAPiP1	2
NM_000533	PLP1	2
NM_199478	PLP1	2
NM_001083913	C10orf26	2
NM_017787	C10orf26	2
NM_001040272	C9orf94	2
NM_015038		2
NM_013318		2
NM_022167	XYLT2	2
NM_015297		2
NM_005158	ABL2	2
NM_007314	ABL2	2
NM_001100108		2
NM_014734	KIAA0247	2
NM_000297	PKD2	2
NM_144682	SLFN13	2
NM_001918	DBT	2
NM_000911	OPRD1	2
NM_021808	GALNT9	2
NM_020717	SHROOM4	2
NM_138967	SCAMP5	2
NM_014045	LRP10	2
NM_001077268	ZFYVE19	2
NM_000990	RPL27A	2
NM_017994	C7orf42	2
NM_006546	IGF2BP1	2
NM_032268	ZNRF1	2
NM_022462	HIF3A	2
NM_152794	HIF3A	2
NM_152795	HIF3A	2
NM_001097611		2
NM_021913	AXL	2
NM_001699	AXL	2
NM_001080410	FBXO41	2
XM_001133261	FBXO41	2
NM_176871	PDLIM2	2
XM_926954	LOC642969	2
XM_931734	LOC642969	2
NM_002629	PGAM1	2
XM_001126103	LOC728188	2
NM_001029891	PGAM4	2
NM_015046	SETX	2
NM_004257	TGFBRAP1	2
NM_152407	GRPEL2	2
NM_005865	PRSS16	2
NM_006074	TRIM22	1
NM_000633	BCL2	1
NM_012334	MYO10	1
XM_001127950	LOC730566	1
XM_001133333	LOC729172	1
NM_014294	TRAM1	1
NM_130466	UBE3B	1
NM_183415	UBE3B	1
NM_001877	CR2	1
NM_001006658	CR2	1
NM_002898	RBMS2	1
NM_006413	RPP30	1
NM_000523	HOXD13	1
NM_020704	FAM40B	1
XM_037557	KIAA0984	1
XM_939476	KIAA0984	1
NM_020125	SLAMF8	1
NM_014211	GABRP	1
NM_030918	SNX27	1
NM_003722	TP73L	1
NM_018017	C10orf118	1
NM_025074	FRAS1	1
XM_940433	LOC651302	1
NM_153708	RTP1	1
NM_173475	DCUN1D3	1
NM_000586	IL2	1
NM_194279	ISCA2	1
NM_000023	SGCA	1
NM_014388	C1orf107	1
NM_001002860	BTBD7	1
NM_000322	PRPH2	1
NM_052885	SLC2A13	1
NM_015044	GGA2	1
NM_139071	SMARCD1	1
NM_003076	SMARCD1	1
NM_020367	PARP11	1
NM_152739	HOXA9	1
NM_005668	ST8SIA4	1
NM_006845	KIF2C	1
NM_015174	KIAA1086	1
XM_378517	MGC15885	1
XM_944564	MGC15885	1
NM_006282	STK4	1
NM_020375	C12orf5	1
NM_001204	BMPR2	1
NM_006106	YAP1	1
NM_152734	C6orf89	1
NM_020884	MYH7B	1
NM_198527	HDDC3	1
NM_005602	CLDN11	1
NM_004737	LARGE	1
NM_133642	LARGE	1
NM_006194	PAX9	1
NM_017902	HIF1AN	1
NM_015207		1
NM_003458	BSN	1
NM_004745	DLGAP2	1
NM_000437	PAFAH2	1
NM_133445	GRIN3A	1
NM_170776	GPR97	1
NM_031448	C19orf12	1
NM_001031726	C19orf12	1
NM_024348	DCTN3	1
NM_007234	DCTN3	1
NM_001880	ATF2	1
NM_022444	SLC13A1	1
XM_930823	LOC642335	1
XM_943378	LOC642335	1
NM_002424	MMP8	1
NM_019004		1
XM_209227	LOC653464	1
NM_001040084	ANXA8L1	1
NM_001630	ANXA8	1
NM_001098845		1
NM_016052	RRP15	1
NM_017580	ZRANB1	1
NM_080625	C20orf160	1
NM_006011	ST8SIA2	1
NM_138703	MAGEE2	1
NM_023923	PHACTR4	1
NM_001048183	PHACTR4	1
NM_000428	LTBP2	1
NM_001100421		1
NM_001100420		1
NM_017447	C21orf91	1
NM_001042574	CRTC3	1
NM_022769	CRTC3	1
NM_032453		1
NM_024558	C14orf138	1
NM_001040662	C14orf138	1
NM_017460	CYP3A4	1
NM_015446	AHCTF1	1
XM_001126456	AHCTF1	1
NM_001099691		1
NM_003236	TGFA	1
NM_001079863	DBI	1
NM_020548	DBI	1
NM_001079862	DBI	1
NM_001097579		1
NM_005300	GPR34	1
NM_000765	CYP3A7	1
NM_173163	NFATC3	1
NM_004555	NFATC3	1
NM_005188	CBL	1
NM_182764	ELMO2	1
NM_133171	ELMO2	1
NM_138972	BACE1	1
NM_012104	BACE1	1
NM_138973	BACE1	1
NM_138971	BACE1	1
NM_024541	C10orf76	1
XM_936101	LOC642031	1
NM_020939	CPNE5	1
NM_014751	MTSS1	1
NM_015178	RHOBTB2	1
NM_021570	BARX1	1
NM_019044	CCDC93	1
NM_020190	OLFML3	1
NM_018036	C14orf103	1
NM_000545	TCF1	1
NM_130811	SNAP25	1
NM_003081	SNAP25	1
NM_182854	SLIC1	1
NM_005225	E2F1	1
NM_016096	ZNF706	1
NM_001042511	ZNF706	1
NM_001042510	ZNF706	1
NM_206914	FAM119B	1
NM_015433	FAM119B	1
NM_002687	PNN	1
NM_138348	FAM105B	1
NM_003804	RIPK1	1
NM_000125	ESR1	1
NM_020699	GATAD2B	1
NM_153825	SLA/LP	1
NM_006555	YKT6	1
NM_000287	PEX6	1
NM_000382	ALDH3A2	1
NM_001031806	ALDH3A2	1
XM_293918	LOC345643	1
XM_938591	LOC345643	1
NM_014763	MRPL19	1
NM_016257	HPCAL4	1
NM_002855	PVRL1	1
NM_001017395	TMCC1	1
NM_015008	TMCC1	1
NM_207111	TRIAD3	1
NM_207116	TRIAD3	1
NM_002353	TACSTD2	1
NM_012062	DNM1L	1
NM_015421	TMEM186	1
NM_145918	CTSL1	1
NM_001912	CTSL1	1
NM_178837	C19orf51	1
NM_024616	C3orf52	1
NM_194286	KIAA1853	1
NM_005658	TRAF1	1
NM_023002	HAPLN4	1
NM_032900	ARHGAP19	1
NM_001031711	ERGIC1	1
NM_004809	STOML1	1
NM_005730	CTDSP2	1
NM_001039888	ANKRD34	1
NM_017506	OR7A5	1
NM_153764	KCNJ1	1
NM_153766	KCNJ1	1
NM_000220	KCNJ1	1
NM_153765	KCNJ1	1
NM_153767	KCNJ1	1
NM_024639	ZNF322A	1
NM_006275	SFRS6	1
NM_032834	ALG10	1
NM_001013620	ALG10B	1
NM_001081573	GAB3	1
NM_080612	GAB3	1
NM_152673	MUC20	1
NM_001098516		1
NM_033120	NKD2	1
NM_005626	SFRS4	1
NM_080737	SYTL4	1
NM_004505	USP6	1
XM_939750	USP32	1
NM_032582	USP32	1
XM_001126087	LOC730459	1
XM_001129466	LOC728473	1
NM_020733		1
NM_005981	TSPAN31	1
NM_014657	KIAA0406	1
NM_014621	HOXD4	1
NM_001031694	SCMH1	1
NM_012236	SCMH1	1
XM_001127710	LOC728653	1
NM_175862	CD86	1
NM_006889	CD86	1
NM_014646	LPIN2	1
NM_007078	LDB3	1
NM_001080114	LDB3	1
NM_032486	DCTN5	1
XM_001132564	LOC728882	1
XM_001133521	MGC51338	1
NM_023927	GRAMD3	1
NM_012320	LYPLA3	1
NM_004491	GRLF1	1
NM_007364	TMED3	1
NM_018203	KLHDC8A	1
NM_207044	ENSA	1
NM_207043	ENSA	1
NM_207047	ENSA	1
NM_030761	WNT4	1
NM_004798	KIF3B	1
NM_016065	MRPS16	1
NM_002350	LYN	1
NM_001111097		1
NM_182498	ZNF428	1
NM_001102421		1
NM_001102420		1
NM_006007	ZFAND5	1
NM_017676	ZH2C2	1
NM_014877	HELZ	1
NM_024909	C6orf134	1
NM_178034	PLA2G4D	1
NM_001024843	TNRC6B	1
NM_015088	TNRC6B	1
NM_013433	TNPO2	1
NM_005746	PBEF1	1
NM_001025390	AMPD3	1
NM_001025389	AMPD3	1
NM_000480	AMPD3	1
NM_198141	GANC	1
NM_016018	PHF20L1	1
XM_932285	LOC644652	1
XM_930805	LOC642426	1
NM_001008393	LOC201725	1
NM_001029858	SLC35F1	1
NM_001012264	RNASE13	1
NM_138395	MARS2	1
NM_005813	PRKD3	1
NM_016210	C3orf18	1
NM_002264	KPNA1	1
NM_001004349	FLJ45422	1
NM_018100	EFHC1	1
NM_006134	TMEM50B	1
NM_001025161	CYP2D6	1
NM_000106	CYP2D6	1
NM_014258	SYCP2	1
NM_001012981	ZKSCAN2	1
NM_001011713	NAT12	1
NM_017694	FLJ20160	1
NM_018452	C6orf35	1
NM_001664	RHOA	1
NM_002242	KCNJ13	1
NM_019601	SUSD2	1
NM_000914	OPRM1	1
NM_173601		1
NM_001099650		1
NM_176877	INADL	1
NM_004808	NMT2	1
NM_000240	MAOA	1
XM_001130189	LOC731598	1
XM_001129850	LOC729291	1
NM_020345	NKIRAS1	1
NM_020975	RET	1
NM_000806	GABRA1	1
NM_198573	C9orf165	1
NM_004332	BPHL	1
XM_001130722	LOC731769	1
XM_001127289	LOC728353	1
NM_004271	LY86	1
NM_000276	OCRL	1
NM_001587	OCRL	1
NM_015393	DKFZP564O0823	1
NM_057170	GIT2	1
NM_057169	GIT2	1
NM_014776	GIT2	1
NM_012096	APPL1	1
NM_001010888	ZC3H12B	1
NM_004100	EYA4	1
NM_172105	EYA4	1
NM_172103	EYA4	1
NM_004272	HOMER1	1
NM_002074	GNB1	1
NM_183075	CYP2U1	1
NM_032449	CC2D1B	1
NM_173598	KSR2	1
NM_005161	AGTRL1	1
NM_001033081	MYCL1	1
NM_001033082	MYCL1	1
NM_021814	ELOVL5	1
NM_174899	FBXO36	1
NM_174902	LDLRAD3	1
NM_014141	CNTNAP2	1
NM_001077619	LOC137886	1
NM_019089	HES2	1
NM_001100829		1
NM_006661	PDE10A	1
NM_015879	ST8SIA3	1
NM_021823	PPCDC	1
NM_022822	KLC2	1
NM_019613	WDR45L	1
NM_015162	ACSBG1	1
NM_016248	AKAP11	1
NM_138981	MAPK10	1
NM_138982	MAPK10	1
NM_138980	MAPK10	1
NM_002753	MAPK10	1
XM_001126701	LOC728148	1
XM_001126714	LOC730662	1
NM_014239	EIF2B2	1
XM_001133149	LOC731486	1
NM_033238	PML	1
NM_018437	HEMGN	1
NM_197978	HEMGN	1
NM_007150		1
XM_931774	LOC643749	1
XM_944444	LOC643749	1
NM_178122	C1orf201	1
NM_001101801		1
NM_001101800		1
NM_016603	C5orf5	1
NM_001821	CHML	1
NM_000168	GLI3	1
NM_018027	FRMD4A	1
NM_207344	SPRYD4	1
NM_014742	TM9SF4	1
NM_018728	MYO5C	1
NM_152222	TNFRSF19L	1
NM_032871	TNFRSF19L	1
NM_052831	C6orf192	1
NM_032873	STS-1	1
NM_019067	GNL3L	1
NM_182833	GDPD4	1
NM_145659	IL27	1
NM_020770	CGN	1
NM_024419	PGS1	1
NM_003371	VAV2	1
NM_138769	RHOT2	1
NM_001042	SLC2A4	1
NM_020772	NUFIP2	1
NM_176677	FLJ36208	1
NM_003747	TNKS	1
NM_024313	NOL12	1
NM_212503	PCTK3	1
NM_002596	PCTK3	1
NM_212502	PCTK3	1
NM_000212	ITGB3	1
NM_138462	ZMYND19	1
NM_001040439	MAPK8IP3	1
NM_015133	MAPK8IP3	1
NM_005063	SCD	1
NM_007055	POLR3A	1
NM_006785	MALT1	1
NM_173844	MALT1	1
NM_175866	UHMK1	1
NM_152874	FAS	1
NM_152876	FAS	1
NM_152877	FAS	1
NM_152872	FAS	1
NM_152871	FAS	1
NM_152873	FAS	1
NM_000043	FAS	1
NM_152875	FAS	1
XM_001132813	LOC728741	1
XM_001132780	LOC728734	1
NM_006051	APBB3	1
NM_133173	APBB3	1
NM_133174	APBB3	1
NM_133172	APBB3	1
NM_178844	NLRC3	1
NM_025081	KIAA1305	1
NM_138296	PTCRA	1
NM_033450	ABCC10	1
NM_006148	LASP1	1
NM_145351	SCARF1	1
NM_001010903	DKFZp779B1540	1
NM_177977	HAP1	1
NM_003949	HAP1	1
NM_001079870	HAP1	1
NM_001079871	HAP1	1
NM_001010922	C1orf178	1
NM_177999	ASB6	1
NM_152914	MGC33894	1
NM_021020	LZTS1	1
NM_198681	PLEKHG5	1
NM_020631	PLEKHG5	1
NM_001042664	PLEKHG5	1
NM_001042663	PLEKHG5	1
NM_001042665	PLEKHG5	1
NM_024887	DHDDS	1
NM_205861	DHDDS	1
NM_031309	SCRT1	1
NM_002655	PLAG1	1
NM_017736	THUMPD1	1
NM_053064	GNG2	1
NM_003362	UNG	1
NM_080911	UNG	1
NM_017617	NOTCH1	1
NM_017747	ANKHD1	1
NM_198253	TERT	1
NM_198255	TERT	1
NM_006532	ELL	1
NM_020456	C13orf1	1
NM_024034	GDAP1L1	1
NM_018490	LGR4	1
NM_153712	TTL	1
NM_080872	UNC5D	1
NM_005934	MLLT1	1
NM_198274	SMYD1	1
NM_174890	ANUBL1	1
NM_153006	NAGS	1
NM_138473	SP1	1
NM_006749	SLC20A2	1
NM_012166	FBXO10	1
NM_018218	USP40	1
XM_001128664	LOC728203	1
NM_152440	FLJ32549	1
NM_022497	MRPS25	1
NM_015326	SRGAP2	1
NM_002092	GRSF1	1
NM_001098477		1
NM_138788	TMEM45B	1
NM_005829	AP3S2	1
NM_022480	KLHL25	1
XM_001127199	LOC728007	1
NM_014771	RNF40	1
NM_033313	CDC14A	1
NM_001100164		1
NM_001100166		1
NM_014721	PHACTR2	1
NM_001100165		1
NM_138385	TMEM129	1
NM_017548	CDV3	1
NM_020638	FGF23	1
NM_002428	MMP15	1
XM_209252	C1orf185	1
XM_942420	C1orf185	1
NM_017628	KIAA1546	1
NM_004279	PMPCB	1
NM_144688	FLJ32658	1
NM_198889	ANKRD17	1
NM_032217	ANKRD17	1
NM_015275	KIAA1033	1
NM_000647	CCR2	1
XM_001133430	LOC729230	1
NM_018252	C1orf75	1
NM_006827	TMED10	1
NM_005324	H3F3B	1
NM_032778	MINA	1
NM_153182	MINA	1
NM_001042533	MINA	1
NM_153607	LOC153222	1
XM_943355	LOC388923	1
XM_373973	LOC388923	1
NM_001636	SLC25A6	1
NM_001099267		1
NM_001032392	PLGLB1	1
NM_002665	PLGLB2	1
NM_006593	TBR1	1
NM_032512	PDZD4	1
NM_018669	WDR4	1
NM_000192	TBX5	1
NM_080717	TBX5	1
NM_181486	TBX5	1
NM_001017995	SH3PXD2B	1
NM_001495	GFRA2	1
NM_024345	WDR32	1
NM_001038707	CDC42SE1	1
NM_020239	CDC42SE1	1
NM_014862	ARNT2	1
NM_024666	FLJ11506	1
XM_001127275	LOC730803	1
XM_001133269	LOC730249	1
NM_000074	CD40LG	1
NM_005864	EFS	1
NM_032459	EFS	1
NM_022912	REEP1	1
NM_000129	F13A1	1
XM_945008	LOC651908	1
XM_932981	LOC645581	1
NM_144994	ANKRD23	1
NM_015995	KLF13	1
NM_005683	GPR55	1
NM_004468	FHL3	1
NM_016028	SUV420H1	1
NM_031444	C22orf13	1
NM_001039577	CCNL2	1
NM_080604	TJAP1	1
NM_004295	TRAF4	1
NM_001077401	ACVRL1	1
NM_000020	ACVRL1	1
NM_007359	CASC3	1
NM_014448	ARHGEF16	1
NM_004277	SLC25A27	1
NM_001013662		1
NM_052978	TRIM9	1
NM_018644	B3GAT1	1
NM_054025	B3GAT1	1
NM_001002034	FAM109B	1
NM_178830	C19orf47	1
NM_182935	MOBP	1
NM_001040665	STEAP2	1
NM_152999	STEAP2	1
NM_147192	DMBX1	1
NM_172225	DMBX1	1
NM_006306	SMC1A	1
NM_001018112	FANCA	1
NM_152375	KLHDC7A	1
NM_017656	ZNF562	1
NM_006729	DIAPH2	1
NM_014423	AFF4	1
NM_021785	RAI2	1
NM_015833	ADARB1	1
NM_001033049	ADARB1	1
NM_001112	ADARB1	1
NM_182562	FLJ39743	1
NM_018048	FLJ10292	1
NM_014337	PPIL2	1
NM_148176	PPIL2	1
NM_148175	PPIL2	1
NM_024755	SLTM	1
NM_001013843	SLTM	1
NM_018294	CWF19L1	1
NM_014485	PGDS	1
NM_013358	PADI1	1
NM_017956	TRMT12	1
NM_005449	FAIM3	1
NM_015534	ZZZ3	1
NM_005826	HNRPR	1
NM_001102398		1
NM_001102397		1
NM_001102399		1
NM_006328	RBM14	1
NM_013255	MKLN1	1
NM_003476	CSRP3	1
XM_001133045	LOC149773	1
XM_001133447	LOC149773	1
NM_001004317	LIN28B	1
NM_052918	SORCS1	1
NM_001013031	SORCS1	1
NM_005955	MTF1	1
NM_006365	C1orf61	1
NM_001001709	FLJ45537	1
NM_147189	FAM110B	1
XM_498841	LOC440748	1
NM_004311	ARL3	1
NM_003480	MFAP5	1
NM_016076	C1orf121	1
NM_001003407	ABLIM1	1
NM_001003408	ABLIM1	1
NM_002313	ABLIM1	1
NM_006720	ABLIM1	1
NM_005268	GJB5	1
NM_138694	PKHD1	1
NM_052909	KIAA1909	1
NM_001017915	INPP5D	1
NM_005541	INPP5D	1
NM_001273	CHD4	1
NM_020908		1
NM_005078	TLE3	1
NM_001105192		1
NM_001025231	KPRP	1
NM_016733	LIMK2	1
NM_005569	LIMK2	1
NM_000823	GHRHR	1
XM_001132080	LOC731007	1
XM_928632	LOC645619	1
NM_203464	AK3L1	1
NM_013410	AK3L1	1
NM_001005353	AK3L1	1
NM_001001412	FAM26C	1
NM_024017	HOXB9	1
NM_152721	DOK6	1
NM_004463	FGD1	1
NM_015051	TXNDC4	1
NM_001037293	PALM2	1
NM_053016	PALM2	1
NM_032242	PLXNA1	1
NM_001099780		1
NM_016170	TLX2	1
NM_001031672	LOC606495	1
NM_001010862	SPIN3	1
NM_015375	RIPK5	1
NM_199462	RIPK5	1
NM_004507	HUS1	1
NM_016173	HEMK1	1
NM_021004	DHRS4	1
NM_198083	DHRS4L2	1
XM_001133080	LOC731356	1
XM_001133093	LOC731356	1
XM_001133076	LOC731356	1
XM_001133109	LOC731356	1
XM_001133116	LOC731356	1
NM_001082488	LOC728635	1
XM_001133105	LOC731356	1
XM_001133065	LOC731356	1
XM_001131304	LOC728635	1
XM_001133102	LOC731356	1
NM_001916	CYC1	1
NM_006212	PFKFB2	1
NM_207127	PAOX	1
NM_147198	WFDC9	1
NM_000525	KCNJ11	1
NM_013442	STOML2	1
NM_005475	SH2B3	1
NM_014936	ENPP4	1
NM_002577	PAK2	1
NM_000278	PAX2	1
NM_003989	PAX2	1
NM_003990	PAX2	1
NM_003987	PAX2	1
NM_003988	PAX2	1
NM_198968	DZIP1	1
NM_014934	DZIP1	1
NM_001008701	LPHN1	1
NM_014921	LPHN1	1
NM_005876		1
NM_012091	ADAT1	1
NM_004418	DUSP2	1
NM_182970	RIMS4	1
NM_001749	CAPNS1	1
NM_001003962	CAPNS1	1
NM_003387	WIPF1	1
NM_001077269	WIPF1	1
NM_001031680	RUNX3	1
NM_004350	RUNX3	1
NM_018977	NLGN3	1
NM_138328	RHBDL3	1
NM_004118	FKHL18	1
NM_025216	WNT10A	1
NM_021267	LASS1	1
NM_017712	PGPEP1	1
NM_033387	FAM78A	1
NM_015555	ZNF451	1
NM_001031623	ZNF451	1
NM_014662	DEPDC5	1
NM_152346	SLC43A2	1
NM_002657	PLAGL2	1
NM_033131	WNT3A	1
NM_015242	CENTD2	1
NM_139181	CENTD2	1
NM_001040118	CENTD2	1
NM_020764	CASKIN1	1
NM_001080530	LOC92017	1
NM_016577	RAB6B	1
NM_032421	CLIP2	1
NM_003388	CLIP2	1
NM_152785	GCET2	1
NM_001008756	GCET2	1
NM_032374	C14orf153	1
NM_033446	FAM125B	1
NM_015431	TRIM58	1
NM_017650	PPP1R9A	1
NM_001097620		1
XM_001134363	FOXK2	1
XM_001134364	FOXK2	1
NM_004514	FOXK2	1
NM_014665	LRRC14	1
NM_004709	CXorf1	1
NM_199135	FOXD4L2	1
NM_001099279		1
NM_199244	FOXD4L4	1
NM_001085476		1
NM_199358	FOXD4L3	1
NM_004263	SEMA4F	1
XM_377073	LOC376475	1
NM_016431	MAPK8IP2	1
NM_012324	MAPK8IP2	1
NM_003118	SPARC	1
NM_022842	CDCP1	1
NM_024028	PCYOX1L	1
NM_207380	FLJ43339	1
NM_015111	N4BP3	1
NM_014586	HUNK	1
NM_022748	TNS3	1
NM_004308	ARHGAP1	1
NM_080861	SPSB3	1
NM_005631	SMO	1
NM_013435	RAX	1
NM_001001685	FLJ45079	1
NM_002999	SDC4	1
NM_024785	FAM124B	1
NM_017728	TMEM104	1
NM_006122	MAN2A2	1
NM_006291	TNFAIP2	1
NM_032679	ZNF577	1
NM_198472	C10orf125	1
NM_001098415		1
NM_016596	HDAC7A	1
NM_001098416		1
NM_015401	HDAC7A	1
NM_015553	PIP3-E	1
NM_032389	ZNF289	1
NM_000795	DRD2	1
NM_016574	DRD2	1
NM_014892	RBM16	1
NM_004981	KCNJ4	1
NM_152868	KCNJ4	1
NM_016263	FZR1	1
NM_004656	BAP1	1
NM_007372	DDX42	1
NM_203499	DDX42	1
NM_001029871	RSPO4	1
NM_001040007	RSPO4	1
NM_004795	KL	1
NM_002737	PRKCA	1
NM_025201	PLEKHQ1	1
NM_001169	AQP8	1
NM_030639	BHLHB9	1
NM_001259	CDK6	1
NM_006482	DYRK2	1
NM_003583	DYRK2	1
NM_133474	ZNF721	1
NM_001718	BMP6	1
NM_024087	ASB9	1
NM_002069	GNAI1	1
NM_001018116	LOC347273	1
NM_001099666		1
XM_928167	LOC645137	1
NM_001023567	GOLGA8B	1
NM_181077	GOLGA8A	1
NM_001012420	GOLGA8G	1
NM_001012423	GOLGA8E	1
XM_001126877	LOC728047	1
XM_001126928	LOC728047	1
XM_001126912	LOC728047	1
XM_926998	LOC643699	1
XM_001126904	LOC728047	1
XM_001126392	LOC727909	1
XM_001126407	LOC727909	1
XM_001126378	LOC727909	1
XM_001127034	LOC728080	1
XM_001127051	LOC728080	1
XM_001127002	LOC728080	1
XM_001127022	LOC728080	1
NM_198181	LOC440295	1
XM_001130526	LOC728636	1
XM_001130555	LOC728636	1
XM_001130543	LOC728636	1
XM_001130536	LOC728636	1
XM_001129399	LOC642346	1
XM_928707	LOC642346	1
XM_925879	LOC642346	1
XM_933066	LOC643696	1
XM_929030	LOC161527	1
XM_925864	LOC642325	1
XM_370876	LOC653643	1
XM_496076	LOC653641	1
NM_014826	CDC42BPA	1
NM_003607	CDC42BPA	1
NM_002745	MAPK1	1
NM_052968	APOA5	1
NM_001098832		1
NM_032837	FAM104A	1
NM_004323	BAG1	1
NM_021637	TMEM35	1
NM_130446	KLHL6	1
NM_152753	SCUBE3	1
NM_000748	CHRNB2	1
NM_018718	TSGA14	1
NM_173622	CDRT4	1
NM_178013	PRIMA1	1
NM_006581	FUT9	1
NM_144586	LYPD1	1
NM_001077427	LYPD1	1
NM_024871	MAP6D1	1
XM_001129814	LOC729272	1
XM_496041	LOC440243	1
XM_208835	LOC440320	1
XM_001128563	FLJ36131	1
XM_001134268	LOC730027	1
XM_928237	LOC645202	1
XM_001125730	LOC727832	1
NM_199511	CCDC80	1
NM_199512	CCDC80	1
NM_001024858	SPTB	1
NM_032287	LDOC1L	1
NM_024092	TMEM109	1
NM_005553	KRTAP5-9	1
NM_019069	WDR5B	1
NM_000725	CACNB3	1
XM_001134369	LOC730107	1
NM_004483	GCSH	1
XM_945736	LOC654085	1
NM_001099733		1
NM_001117	ADCYAP1	1
NM_024551	ADIPOR2	1
NM_180989	GPR180	1
XM_370636	LOC387787	1
XM_945912	LOC650826	1
NM_006180	NTRK2	1
NM_001018064	NTRK2	1
NM_005068	SIM1	1
NM_018371	ChGn	1
NM_144571	CNOT6L	1
NM_007013	WWP1	1
NM_021181	SLAMF7	1
NM_014945	ABLIM3	1
NM_178042	ACTL6A	1
NM_177989	ACTL6A	1
NM_004301	ACTL6A	1
NM_014797	ZBTB24	1
NM_198924	TRIM73	1
XM_351723	LOC375593	1
XM_353628	LOC378125	1
NM_198853	TRIM74	1
NM_001790	CDC25C	1
NM_022809	CDC25C	1
NM_138959	VANGL1	1
NM_013423	ARHGAP6	1
NM_001174	ARHGAP6	1
NM_013427	ARHGAP6	1
NM_021083	XK	1
NM_015163	TRIM9	1
NM_031476	CRISPLD2	1
NM_177405	CECR1	1
NM_017424	CECR1	1
NM_022150	NPVF	1
NM_025160	WDR26	1
NM_173499	SPATA8	1
NM_001939	DRP2	1
NM_006371	CRTAP	1
NM_152857	WTAP	1
NM_152858	WTAP	1
NM_001018070	CORO1B	1
NM_020441	CORO1B	1
NM_002201	ISG20	1
NM_003916	AP1S2	1
NM_001031716	OBFC2A	1
NM_001879	MASP1	1
NM_197949	CLEC7A	1
NM_197950	CLEC7A	1
NM_022570	CLEC7A	1
NM_197948	CLEC7A	1
NM_197947	CLEC7A	1
NM_002401	MAP3K3	1
NM_203351	MAP3K3	1
NM_005472	KCNE3	1
NM_022121	PERP	1
XM_001127362	KIAA0574	1
NM_017763	RNF43	1
NM_014910	ZNF507	1
NM_001004313	LOC388335	1
NM_032865	TNS4	1
NM_033409	C20orf54	1
NM_018207	TRIM62	1
NM_178448	C9orf140	1
NM_000219	KCNE1	1
NM_024963	FBXL18	1
XM_379517	LOC401399	1
XM_380142	LOC401399	1
XM_938040	LOC401399	1
NM_018988	GFOD1	1
NM_004474	FOXD2	1
NM_024301	FKRP	1
NM_001039885	FKRP	1
NM_001111019		1
NM_145117	NAV2	1
NM_182964	NAV2	1
NM_001111018		1
NM_198715	PTGER3	1
NM_001421	ELF4	1
NM_005907	MAN1A1	1
NM_017754	C6orf107	1
NM_198124	CSMD3	1
NM_198123	CSMD3	1
NM_052900	CSMD3	1
NM_016605	FAM53C	1
XM_001128291	PARP8	1
NM_002076	GNS	1
NM_003724	JRK	1
NM_198511	LANCL3	1
NM_003841	TNFRSF10C	1
NM_033656	BRWD1	1
NM_012400	PLA2G2D	1
NM_002858	ABCD3	1
NM_000337	SGCD	1
NM_001011516	PDLIM5	1
NM_001011515	PDLIM5	1
NM_172069	PLEKHH2	1
NM_014924	KIAA0831	1
NM_152253	CHKB	1
NM_018096	NLE1	1
NM_001014445	NLE1	1
NM_014911	AAK1	1
NM_144718	CCDC52	1
NM_024638	QTRTD1	1
NM_015354	NUP188	1
NM_016538	SIRT7	1
NM_024565	CCNJL	1
NM_002634	PHB	1
NM_015140	TTLL12	1
NM_005526	HSF1	1
NM_017790	RGS3	1
NM_015352	POFUT1	1
XM_001127807	LOC642255	1
XM_001126718	LOC642255	1
NM_205845	AKR1C2	1
NM_001354	AKR1C2	1
NM_001353	AKR1C1	1
NM_014372	RNF11	1
NM_014964	EPN2	1
NM_001102664		1
NM_148921	EPN2	1
NM_024773	JMJD5	1
NM_005596	NFIB	1
NM_023034	WHSC1L1	1
XM_001131300	LOC149157	1
XM_001132625	LOC149157	1
NM_147202	C9orf25	1
NM_007354	C3orf27	1
NM_006941	SOX10	1
NM_013389	NPC1L1	1
NM_001101648		1
NM_021153	CDH19	1
NM_014830	ZBTB39	1
NM_002579	PALM	1
NM_001040134	PALM	1
NM_138991	BACE2	1
NM_138992	BACE2	1
NM_012105	BACE2	1
NM_178457	C20orf174	1
NM_001099408		1
NM_001042601	TTC14	1
NM_001010883	FAM102B	1
NM_000153	GALC	1
XM_001132383	LOC732253	1
NM_001101676		1
NM_032214	SLA2	1
NM_175077	SLA2	1
NM_020127	TUFT1	1
NM_001039396	MPEG1	1
NM_152754	SEMA3D	1
NM_030793	FBXO38	1
NM_205836	FBXO38	1
NM_000354	SERPINA7	1
NM_004863	SPTLC2	1
NM_005840	SPRY3	1
NM_016593	CYP39A1	1
NM_002070	GNAI2	1
NM_203355	CTAGE5	1
NM_203354	CTAGE5	1
NM_203356	CTAGE5	1
NM_005930	CTAGE5	1
XM_001131309	LOC731099	1
XM_001127462	LOC728089	1
NM_007054	KIF3A	1
NM_015344	LEPROTL1	1
NM_133646	ZAK	1
NM_201544	LGALS8	1
NM_006499	LGALS8	1
NM_201545	LGALS8	1
NM_201543	LGALS8	1
NM_138572	TBN	1
NM_173829	P18SRP	1
NM_001008225	CNOT4	1
NM_138464		1
NM_182898	CREB5	1
NM_004904	CREB5	1
NM_001011666	CREB5	1
NM_182899	CREB5	1
NM_152902	TIPRL	1
NM_022716	PRRX1	1
NM_006902	PRRX1	1
NM_000958	PTGER4	1
XM_001126290	LOC727908	1
NM_015383	NBPF14	1
NM_173638	NBPF15	1
NM_001102663		1
NM_032264	NBPF3	1
XM_001128986	LOC728980	1
NM_183372	NBPF11	1
NM_001101663		1
NM_007350	PHLDA1	1
NM_002524	NRAS	1
NM_021648	TSPYL4	1
NM_005672	PSCA	1
NM_013402	FADS1	1
NM_014607	UBXD2	1
NM_015458	MTMR9	1
NM_022766	CERK	1
NM_058166	TRIM6	1
NM_001003818	TRIM6	1
NM_002553	ORC5L	1
NM_001010898	SLC6A17	1
NM_173505	ANKRD29	1
NM_030883	OR2H1	1
NM_194247	HNRPA3	1
NM_017738	C9orf39	1
NM_004985	KRAS	1
NM_033360	KRAS	1
NM_016087	WNT16	1
NM_057168	WNT16	1
NM_001039618	CREBZF	1
NM_033127	LZTR2	1
NM_182762	7A5	1
NM_001189	BAPX1	1
NM_004738	VAPB	1
NM_000697	ALOX12	1
NM_004172	SLC1A3	1
NM_006099	PIAS3	1
NM_138731	MIPOL1	1
NM_016540	GPR83	1
NM_024776		1
NM_013989	DIO2	1
NM_001007023	DIO2	1
NM_000793	DIO2	1
NM_018195	C11orf57	1
NM_001082969	C11orf57	1
NM_001082970	C11orf57	1
NM_017686	GDAP2	1
NM_000158	GBE1	1
NM_000393	COL5A2	1
XM_208043	LOC283116	1
NM_182635	C9orf164	1
NM_178043	LARP2	1
NM_020358	TRIM49	1
XM_926073	LOC653111	1
NM_007036	ESM1	1
NM_014965	TRAK1	1
NM_020815	PCDH10	1
NM_007106	UBL3	1
NM_198595	AFAP1	1
NM_021638	AFAP1	1
NM_003178	SYN2	1
NM_015316	PPP1R13B	1
NM_005500	SAE1	1

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Immunostimulatory motif search results

UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).

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Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

Parameter	Spec. Score cut-off	Colour	Comment
Hit to same gene		Colour	Hits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit	≥80	Colour	Hits are very likely to cause an off-target effect
Medium scoring hit	<80¸≥40	Colour	Hits with a small chance of causing an off target effect.
Low scoring hit		Colour	Hits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-off	Colour
Match	Colour
Wobble base pairs (G-U)	Colour
Critical bases (none)	Colour
0.6 bits	Colour
0.4 bits	Colour
0.2 bits	Colour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer

For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317