VIRsiRNAdb

SpecificityServer - An siRNA design program for determining siRNA specificity
Automatic recommendation
Warning - siRNA is specific for only the antisense (guide) strand

24 hits were found for GGGUAAUGAAGCAGCAAAA (7 guide strand hits and 17 sense strand hits.)

Hits to Guide strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_197941

ADAMTS6

2083

2101

a

G

G

U

c

A

U

G

A

A

G

C

A

G

C

A

A

A

A

46

2

14

bc

false

<90%

7289

NM_004723

ARHGEF2

723

741

a

G

G

U

g

A

U

G

A

A

G

C

A

G

C

A

A

g

A

43

3

12

c

false

<90%

4093

NM_033028

BBS4

403

421

a

u

a

U

A

A

U

G

A

A

G

C

A

G

C

u

A

A

A

40

4

12

c

false

<90%

2482

NM_001007253

ERV3

2264

2282

G

G

G

g

A

A

U

G

A

A

G

C

A

G

g

A

A

A

u

33

3

10

c

false

<90%

2829

NM_015852

ZNF117

116

134

G

G

G

g

A

A

U

G

A

A

G

C

A

G

g

A

A

A

u

33

3

10

c

false

<90%

6404

XR_018673

LOC645936

403

421

G

a

G

U

A

A

a

G

A

A

G

C

A

G

C

A

A

A

u

17

3

11

bc

false

<90%

2132

XR_017006

LOC645936

403

421

G

a

G

U

A

A

a

G

A

A

G

C

A

G

C

A

A

A

u

17

3

11

bc

false

<90%

2132

Hits to Sense strand

Accession

Gene

Start

End

Details of mismatches

Spec. Score

Mismatches

Contiguous

Jackson style specificity

Hits similar gene

HSP Score

HSP % Identity

HSP length

Gene Length

1

2

3

4

5

6

7

8

9

10

11

12

13

14

15

16

17

18

19

NM_022479

WBSCR17

2938

2956

g

c

U

U

G

C

U

G

C

U

U

C

A

U

U

A

C

u

C

83

3

15

ac

false

<90%

3298

NM_001039613

IAH1

697

715

c

U

U

U

G

C

U

G

C

U

U

C

c

U

U

A

C

u

g

79

4

11

false

<90%

951

NM_002203

ITGA2

5683

5701

a

U

U

U

G

C

U

G

C

U

U

C

A

U

U

c

C

a

a

64

4

14

c

false

<90%

7878

NM_014345

ZNF318

5753

5771

a

g

U

U

G

C

U

G

C

U

U

C

A

U

U

c

C

C

C

60

3

13

c

false

<90%

8021

NM_017554

PARP14

6540

6558

a

g

U

U

G

C

U

G

C

U

U

C

A

U

U

A

a

C

a

58

4

14

ac

false

<90%

6903

NM_004251

RAB9A

904

922

U

g

U

U

G

C

U

G

C

U

U

C

A

U

U

A

g

u

u

57

4

14

ac

false

<90%

1097

NM_017912

HERC6

3838

3856

U

U

U

U

G

C

U

G

C

U

U

C

A

c

U

g

C

C

u

49

3

13

c

false

<90%

3903

XM_001126148

LOC730511

446

464

U

U

U

U

u

C

U

G

C

U

U

C

A

U

U

A

u

u

a

17

4

11

c

false

<90%

1163

XM_001126270

LOC727977

446

464

U

U

U

U

u

C

U

G

C

U

U

C

A

U

U

A

u

u

a

17

4

11

c

false

<90%

1163

XM_001127639

LOC730886

689

707

U

U

U

U

u

C

U

G

C

U

U

C

A

U

U

A

u

u

a

17

4

11

c

false

<90%

1406

NM_201567

CDC25A

2308

2326

U

U

U

U

a

C

U

G

C

U

U

C

A

U

U

A

g

g

u

17

4

11

c

false

<90%

3597

NM_001789

CDC25A

2428

2446

U

U

U

U

a

C

U

G

C

U

U

C

A

U

U

A

g

g

u

17

4

11

c

false

<90%

3717

XM_496814

LOC441155

556

574

U

U

U

U

u

C

U

G

C

U

U

C

A

U

U

A

u

u

a

17

4

11

c

false

<90%

4956

XM_942821

LOC441155

556

574

U

U

U

U

u

C

U

G

C

U

U

C

A

U

U

A

u

u

a

17

4

11

c

false

<90%

4957

XM_931006

LOC441155

797

815

U

U

U

U

u

C

U

G

C

U

U

C

A

U

U

A

u

u

a

17

4

11

c

false

<90%

5197

XM_942815

LOC441155

797

815

U

U

U

U

u

C

U

G

C

U

U

C

A

U

U

A

u

u

a

17

4

11

c

false

<90%

5198

NM_014715

RICS

5677

5695

c

U

U

c

c

C

U

G

C

U

U

C

A

U

U

A

C

C

C

9

3

14

bc

false

<90%

6480

---

3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 898
View matched accessions

3 prime seed match details

Accession	Gene name	Hits to this gene
NM_019014	POLR1B	2
NM_000024	ADRB2	2
NM_001098813		2
NM_015146		2
NM_001098812		2
XM_944290	KIAA0492	2
XM_378914	KIAA0492	2
NM_014850	SRGAP3	2
NM_001033117	SRGAP3	2
NM_001001668	ZNF470	2
NM_000481	AMT	2
NM_194247	HNRPA3	2
NM_001013659	ZNF793	2
NM_001105543		2
NM_015257	KIAA0286	2
NM_145259	ACVR1C	2
NM_001111031		2
NM_001111033		2
NM_001111032		2
NM_018283	NUDT15	2
NM_171982	TRIM35	2
NM_004873	BAG5	2
NM_001015049	BAG5	2
NM_001015048	BAG5	2
NM_017650	PPP1R9A	2
NM_133334	WHSC1	2
NM_144963	FAM91A1	2
NM_016217	HECA	2
NM_024638	QTRTD1	2
NM_006682	FGL2	2
NM_182907	PRDM1	2
NM_001198	PRDM1	2
NM_017552		2
NM_144607	CYB5D1	2
NM_001024647	RAB3IP	2
NM_022456	RAB3IP	2
NM_175624	RAB3IP	2
NM_175625	RAB3IP	2
NM_175623	RAB3IP	2
NM_002061	GCLM	2
NM_174916	UBR1	2
NM_001077196	PDE11A	2
NM_001077197	PDE11A	2
NM_016953	PDE11A	2
NM_018566	YOD1	2
NM_018159	NUDT11	2
NM_000151	G6PC	2
NM_173463	DKFZp761B107	2
NM_004348	RUNX2	2
NM_001015051	RUNX2	2
NM_001024630	RUNX2	2
NM_014959	CARD8	2
NM_198493	ANKRD45	2
NM_005722	ACTR2	2
NM_001005386	ACTR2	2
NM_001098672		2
NM_001010906		2
NM_002911	UPF1	1
NM_003710	SPINT1	1
NM_001032367	SPINT1	1
NM_181642	SPINT1	1
NM_207352	CYP4V2	1
NM_004703	RABEP1	1
NM_001083585	RABEP1	1
NM_014912	CPEB3	1
NM_001033578	SGK3	1
NM_013257	SGK3	1
NM_170709	SGK3	1
NM_198513	PHF20L1	1
NM_000017	ACADS	1
NM_015367	BCL2L13	1
NM_006848	CCDC85B	1
NM_138761	BAX	1
NM_138765	BAX	1
NM_138763	BAX	1
NM_138764	BAX	1
NM_001412	EIF1AX	1
NM_001012515	FECH	1
NM_000140	FECH	1
XM_944677	LOC338758	1
XM_931359	LOC338758	1
NM_032579	RETNLB	1
NM_003761	VAMP8	1
NM_207660	ZC3H14	1
NM_024824	ZC3H14	1
NM_207661	ZC3H14	1
NM_207662	ZC3H14	1
NM_175907	ZADH2	1
NM_000326	RLBP1	1
NM_006330	LYPLA1	1
NM_080669	SLC46A1	1
NM_203453	PPAPDC2	1
NM_000448	RAG1	1
NM_003104	SORD	1
NM_001079530	LOC653275	1
NM_032545	CFC1	1
NM_178310	SNAI3	1
NM_020123	TM9SF3	1
NM_033549	TRIM41	1
NM_001008401	ZNF761	1
NM_033542	SYS1	1
NM_000849	GSTM3	1
NM_004992	MECP2	1
NM_001018067	SERBP1	1
NM_015640	SERBP1	1
NM_001018069	SERBP1	1
NM_001018068	SERBP1	1
NM_001047	SRD5A1	1
NM_153184	CADM2	1
NM_020766	PCDH19	1
NM_001105243		1
NM_015980	HMP19	1
NM_000569	FCGR3A	1
NM_001001436	LOC388272	1
NM_022443	MLF1	1
NM_016356	DCDC2	1
NM_012398	PIP5K1C	1
NM_198066	GNPNAT1	1
NM_001010888	ZC3H12B	1
NM_153207	AEBP2	1
XM_927767	LOC653505	1
XM_927706	LOC644591	1
NM_020738	KIDINS220	1
NM_003298	NR2C2	1
NM_000538	RFXAP	1
NM_153338	GGT6	1
NM_006588	SULT1C4	1
NM_152729	NT5DC1	1
NM_024906	SCD5	1
NM_006179	NTF5	1
NM_080792	SIRPA	1
NM_001040023	SIRPA	1
NM_001040022	SIRPA	1
NM_001100829		1
NM_178827	IQUB	1
NM_172071	RC3H1	1
NM_130809	PRRC1	1
NM_007157	ZXDB	1
NM_173545	C2orf13	1
NM_003932	ST13	1
NM_001042599	ERBB4	1
NM_005235	ERBB4	1
NM_015327	SMG5	1
NM_001080415	SR140	1
XM_940802	SR140	1
NM_144767	AKAP13	1
NM_006738	AKAP13	1
NM_007200	AKAP13	1
XM_001128799	MAP3K2	1
NM_005759	ABI2	1
XM_001126750	ABI2	1
NM_002396	ME2	1
NM_001046	SLC12A2	1
NM_002427	MMP13	1
NM_182487	OLFML2A	1
NM_138715	MSR1	1
NM_138716	MSR1	1
NM_001085460		1
NM_001085469		1
NM_001085465		1
NM_001085466		1
NM_001085462		1
NM_001085461		1
NM_001085458		1
NM_001085468		1
NM_001085463		1
NM_001085467		1
NM_001331	CTNND1	1
NM_001085459		1
NM_001085464		1
NM_017748	CCDC49	1
NM_004274	AKAP6	1
NM_001012716	C18orf56	1
NM_182757	IBRDC2	1
NM_000216	KAL1	1
NM_013286	RBM15B	1
NM_199050	C21orf25	1
NM_015500	C21orf25	1
XM_032945	C21orf25	1
NM_001009554	MFAP3L	1
NM_021647	MFAP3L	1
NM_003285	TNR	1
XM_166659	OTUD1	1
XM_001134465	OTUD1	1
NM_014553	TFCP2L1	1
NM_015157	PHLDB1	1
NM_006791	MORF4L1	1
NM_206839	MORF4L1	1
NM_018084	KIAA1212	1
NM_005082	TRIM25	1
NM_015020	PHLPPL	1
NM_020717	SHROOM4	1
NM_203500	KEAP1	1
NM_012289	KEAP1	1
NM_030949	PPP1R14C	1
NM_001025266	LOC285382	1
NM_006025	P11	1
NM_018590	GALNACT-2	1
NM_004845	PCYT1B	1
NM_006096	NDRG1	1
NM_006073	TRDN	1
NM_152624	DCP2	1
NM_003934	FUBP3	1
XM_001125825	FUBP3	1
XM_001128545	FUBP3	1
NM_002303	LEPR	1
NM_018638	ETNK1	1
NM_018130	SHQ1	1
NM_133493	CD109	1
NM_152564	VPS13B	1
NM_017890	VPS13B	1
NM_001004313	LOC388335	1
NM_007021	C10orf10	1
NM_020871	LRCH2	1
NM_004329	BMPR1A	1
NM_017911	FAM118A	1
NM_001104595		1
NM_080654	CCDC34	1
NM_013244	MGAT4C	1
NM_022091	ASCC3	1
NM_031271	TEX15	1
XM_209227	LOC653464	1
NM_182830	MDGA2	1
NM_000129	F13A1	1
NM_031474	NRIP2	1
NM_020802	KIAA1377	1
NM_199320	PHF17	1
NM_005797	EVA1	1
NM_000349	STAR	1
NM_001007243	STAR	1
XM_001133877	FLJ41278	1
XM_001129851	FLJ41278	1
NM_012192	FXC1	1
NM_001002915	IGFL2	1
NM_003766	BECN1	1
NM_015092	SMG1	1
NM_152772	TCP11L2	1
NM_153697	ANKRD44	1
NM_001098625		1
NM_016475	C14orf100	1
NM_001018065	NTRK2	1
NM_001018066	NTRK2	1
NM_001080480	MBOAT1	1
XM_001131050	MBOAT1	1
XM_001131044	MBOAT1	1
NM_080593	HIST1H2BK	1
NM_014817	KIAA0644	1
NM_052905	FMNL2	1
NM_018024	C8orf32	1
NM_014395	DAPP1	1
NM_001655	ARCN1	1
NM_001008493	ENAH	1
NM_018212	ENAH	1
NM_033313	CDC14A	1
NM_004594	SLC9A5	1
NM_153354	TMEM161B	1
NM_012129	CLDN12	1
NM_173536	GABRG1	1
NM_000164	GIPR	1
NM_006325	RAN	1
NM_032138	KBTBD7	1
NM_001007233	ERCC8	1
NM_000082	ERCC8	1
NM_002227	JAK1	1
NM_012463	ATP6V0A2	1
NM_031281	FCRL5	1
NM_198578	LRRK2	1
NM_004310	RHOH	1
XM_938853	LOC285484	1
XM_376303	LOC285484	1
NM_001518	GTF2I	1
NM_032999	GTF2I	1
NM_033000	GTF2I	1
NM_033001	GTF2I	1
XM_001133646	LOC732437	1
XM_001130623	LOC645733	1
XM_374004	LOC645733	1
NM_018210	FLJ10769	1
NM_005333	HCCS	1
NM_031444	C22orf13	1
NM_052943	FAM46B	1
NM_015359	SLC39A14	1
NM_153710	C9orf96	1
NM_004781	VAMP3	1
NM_000859	HMGCR	1
NM_203446	SYNJ1	1
NM_033106	GALP	1
NM_152570	LINGO2	1
NM_001042492	NF1	1
NM_000267	NF1	1
NM_017784	OSBPL10	1
NM_005253	FOSL2	1
NM_012434	SLC17A5	1
NM_052918	SORCS1	1
NM_001013031	SORCS1	1
NM_032458	PHF6	1
NM_001015877	PHF6	1
NM_016575	NT5DC3	1
NM_025015	HSPA12A	1
NM_001031692	LRRC17	1
NM_005824	LRRC17	1
NM_001259	CDK6	1
NM_207404	ZNF662	1
NM_007054	KIF3A	1
NM_032750	ABHD14B	1
NM_182831	TNT	1
NM_017791	C14orf58	1
NM_030759	NRBF2	1
NM_005898	CAPRIN1	1
NM_005239	ETS2	1
NM_182517	C1orf210	1
NM_004093	EFNB2	1
NM_025235	TNKS2	1
NM_006526	ZNF217	1
XM_378661	C17orf51	1
XM_944416	C17orf51	1
NM_006212	PFKFB2	1
NM_025138	C13orf23	1
NM_170719	C13orf23	1
NM_024743	UGT2A3	1
NM_003617	RGS5	1
NM_032966	BLR1	1
NM_001716	BLR1	1
NM_024642	GALNT12	1
NM_001039547	GK5	1
NM_020466	LYRM2	1
NM_014797	ZBTB24	1
XM_001133827	LOC731816	1
NM_003215	TEC	1
NM_001077484	SLC38A1	1
NM_030674	SLC38A1	1
NM_003222	TFAP2C	1
NM_201999	ELF2	1
NM_006874	ELF2	1
XM_928022	LOC644935	1
XM_001130944	LOC644935	1
NM_002451	MTAP	1
NM_001201	BMP3	1
NM_015385	SORBS1	1
NM_001034954	SORBS1	1
NM_001034957	SORBS1	1
NM_001034955	SORBS1	1
NM_001034956	SORBS1	1
NM_006434	SORBS1	1
NM_024991	SORBS1	1
NM_000396	CTSK	1
NM_022367	SEMA4A	1
NM_006255	PRKCH	1
NM_033224	PURB	1
XM_929331	LOC646405	1
XM_940374	LOC651239	1
NM_020362	C1orf128	1
NM_172060	EYA1	1
NM_000503	EYA1	1
NM_172058	EYA1	1
NM_172059	EYA1	1
NM_018050	MANSC1	1
NM_033121	ANKRD13A	1
NM_006300	ZNF230	1
NM_181789	GLDN	1
NM_172016	TRIM39	1
NM_021253	TRIM39	1
NM_032148	SLC41A2	1
NM_005250	FOXL1	1
NM_001099413		1
NM_001099412		1
NM_006766	MYST3	1
NM_001498	GCLC	1
NM_002711	PPP1R3A	1
NM_003557	PIP5K1A	1
NM_001942	DSG1	1
NM_001693	ATP6V1B2	1
NM_022491	SUDS3	1
NM_006624	ZMYND11	1
XM_001133595	LOC729324	1
XM_001133813	LOC731757	1
NM_000913	OPRL1	1
NM_182647	OPRL1	1
NM_001080435	WHDC1	1
XM_939866	WHDC1	1
NM_020128	MDM1	1
NM_005828	WDR68	1
NM_000163	GHR	1
NM_001105518		1
NM_017673	C1orf26	1
NM_014447	ARFIP1	1
NM_001025595	ARFIP1	1
NM_001025593	ARFIP1	1
NM_018252	C1orf75	1
XM_291095	LOC339970	1
XM_943391	LOC339970	1
NM_001018090	Gcom1	1
NM_001018102	GRINL1A	1
NM_015532	GRINL1A	1
NM_001018091	Gcom1	1
NM_000670	ADH4	1
NM_006252	PRKAA2	1
NM_014947	FOXJ3	1
NM_001018058	TFEC	1
NM_012252	TFEC	1
NM_020778	ALPK3	1
NM_000173	GP1BA	1
NM_019610	RBMXL1	1
NM_002247	KCNMA1	1
NM_182540	DDX26B	1
NM_005378	MYCN	1
NM_016621	PHF21A	1
NM_001101802		1
NM_020910		1
NM_003793	CTSF	1
NM_030643	APOL4	1
NM_145660	APOL4	1
NM_021601	CD79A	1
NM_001783	CD79A	1
NM_020964	KIAA1632	1
XM_001133420	LOC728991	1
NM_032781	PTPN5	1
NM_001039970	PTPN5	1
NM_006906	PTPN5	1
NM_004720	EDG4	1
NM_001085375		1
NM_015393	DKFZP564O0823	1
NM_031949	TTLL2	1
NM_017709	FAM46C	1
NM_001080115	LDB3	1
NM_001080116	LDB3	1
NM_003045	SLC7A1	1
NM_001010971	SAMD13	1
NM_016467	ORMDL1	1
NM_148169	FBXO17	1
NM_024907	FBXO17	1
NM_024674	LIN28	1
NM_001803	CD52	1
NM_002128	HMGB1	1
NM_183240	TMEM37	1
NM_001077654	TNFAIP8	1
NM_014350	TNFAIP8	1
NM_004678	BPY2	1
NM_001002760	BPY2B	1
NM_001002761	BPY2C	1
NM_001007534	C3orf56	1
NM_016131	RAB10	1
NM_001040628	NCALD	1
NM_001040626	NCALD	1
NM_001040625	NCALD	1
NM_032041	NCALD	1
NM_001040629	NCALD	1
NM_001040624	NCALD	1
NM_001040627	NCALD	1
NM_001040630	NCALD	1
NM_015215	CAMTA1	1
NM_003941	WASL	1
NM_022823	FNDC4	1
NM_133371	MYOZ3	1
NM_013365	GGA1	1
NM_001001560	GGA1	1
NM_024541	C10orf76	1
NM_033027	AXUD1	1
NM_018346	RSAD1	1
NM_001004342	TRIM67	1
NM_002820	PTHLH	1
NM_198964	PTHLH	1
NM_020122	KCMF1	1
NM_015270	ADCY6	1
NM_020983	ADCY6	1
NM_032373	PCGF5	1
NM_014659	HISPPD2A	1
NM_001024463	HISPPD2A	1
NM_005670	EPM2A	1
NM_148957	TNFRSF19	1
XM_932244	LOC653160	1
XM_945233	LOC653160	1
NM_015397	WDR40A	1
NM_014911	AAK1	1
NM_182663	RASSF5	1
NM_182664	RASSF5	1
NM_182665	RASSF5	1
NM_001040174	HTR4	1
NM_000943	PPIC	1
NM_005086	SSPN	1
NM_014423	AFF4	1
NM_001195	BFSP1	1
NM_015149	RGL1	1
NM_014141	CNTNAP2	1
NM_001620	AHNAK	1
NM_015555	ZNF451	1
NM_001031623	ZNF451	1
XM_926086	LOC653114	1
NM_001098718		1
XM_930068	LOC653809	1
NM_001219	CALU	1
NM_012249	RHOQ	1
NM_004232	SOCS6	1
NM_001001711	DDI1	1
XM_001133623	PTPLAD1	1
NM_001033564	LOC619208	1
NM_001080460	LOC344657	1
NM_024512	LRRC2	1
NM_001034914	KCNIP3	1
NM_013434	KCNIP3	1
NM_012316	KPNA6	1
XM_001132516	LOC729049	1
NM_198461	LONRF2	1
NM_015053	PPFIA4	1
NM_005819	STX6	1
NM_178126	LOC162427	1
NM_006510	TRIM27	1
XM_001131068	LOC729696	1
XM_001129643	LOC731435	1
NM_033343	LHX4	1
NM_033091	TRIM4	1
NM_033017	TRIM4	1
NM_014803	ZNF518	1
NM_001024858	SPTB	1
NM_001101339		1
NM_144723	ZMAT2	1
NM_021916	ZNF70	1
NM_172208	TAPBP	1
NM_030913	SEMA6C	1
NM_004656	BAP1	1
NM_006782	ZFPL1	1
NM_000843	GRM6	1
NM_174899	FBXO36	1
NM_014007	ZBTB43	1
NM_001013655	LOC389834	1
XM_001125792	LOC727834	1
XM_926013	LOC642398	1
NM_004687	MTMR4	1
NM_006965	ZNF24	1
NM_030623	SKIP	1
NM_021199	SQRDL	1
NM_080829	C20orf175	1
NM_007278	GABARAP	1
NM_025202	EFHD1	1
NM_002747	MAPK4	1
NM_002737	PRKCA	1
NM_153607	LOC153222	1
NM_024770	METTL8	1
NM_006061	CRISP3	1
NM_020732	ARID1B	1
NM_017519	ARID1B	1
NM_175863	ARID1B	1
XM_001133842	LOC729446	1
NM_152440	FLJ32549	1
NM_031455	CCDC3	1
NM_004827	ABCG2	1
NM_015634	KIAA1279	1
NM_014774	KIAA0494	1
NM_018247	TMEM30A	1
NM_001037165	FOXK1	1
NM_197956	C9orf90	1
NM_000259	MYO5A	1
NM_016205	PDGFC	1
NM_015564	LRRTM2	1
NM_001032409	OAS1	1
NM_016816	OAS1	1
NM_004613	TGM2	1
NM_001421	ELF4	1
NM_153619	SEMA6D	1
NM_153618	SEMA6D	1
NM_153616	SEMA6D	1
NM_153617	SEMA6D	1
NM_020858	SEMA6D	1
NM_001002258	ATP5G3	1
NM_001689	ATP5G3	1
NM_203413	C17orf81	1
NM_015362	C17orf81	1
NM_203414	C17orf81	1
NM_203415	C17orf81	1
NM_002566	P2RY11	1
NM_001017924	LRRC22	1
NM_173475	DCUN1D3	1
NM_004034	ANXA7	1
NM_001156	ANXA7	1
NM_207391	RGS9BP	1
NM_001759	CCND2	1
NM_032788	ZNF514	1
XM_941162	LOC400950	1
XM_376049	LOC400950	1
NM_012072	CD93	1
NM_133264	WIPF2	1
NM_014518	ZNF229	1
NM_022778	CCDC21	1
NM_138782	FCHO2	1
NM_194285	SPTY2D1	1
NM_020830	WDFY1	1
NM_177967	UBAC2	1
NM_001918	DBT	1
NM_005596	NFIB	1
NM_002623	PFDN4	1
NM_016376	ANKFY1	1
NM_153255	MCM9	1
NM_213589	RAPH1	1
NM_014945	ABLIM3	1
NM_198506	FLJ44691	1
XM_001128518	LOC731119	1
XM_001128548	LOC728812	1
NM_173829	P18SRP	1
NM_020655	JPH3	1
NM_032861	SERAC1	1
NM_005272	GNAT2	1
NM_000898	MAOB	1
NM_144721	THAP6	1
NM_014616	ATP11B	1
NM_171998	RAB39B	1
NM_015425	POLR1A	1
XM_934649	C1orf34	1
XM_945958	C1orf34	1
NM_005497	GJA7	1
NM_001080383	GJA7	1
NM_177976	ARL6	1
NM_032146	ARL6	1
NM_007050	PTPRT	1
NM_133170	PTPRT	1
NM_032622	LNX1	1
NM_207306		1
NM_016221	DCTN4	1
NM_003291	TPP2	1
NM_021255	PELI2	1
NM_003074	SMARCC1	1
NM_018937	PCDHB3	1
NM_014500	HTATSF1	1
XM_001128367	LOC439949	1
XM_001129241	LOC439949	1
NM_006635	ZNF460	1
NM_001038707	CDC42SE1	1
NM_020239	CDC42SE1	1
NM_004091	E2F2	1
NM_000609	CXCL12	1
NM_014240	LIMD1	1
NM_002015	FOXO1A	1
NM_001029883	FLJ34931	1
NM_000108	DLD	1
NM_014106	ZNF770	1
NM_018425	PI4KII	1
NM_018246	CCDC25	1
NM_006933	SLC5A3	1
NM_015313	ARHGEF12	1
NM_173631	ZNF547	1
NM_025146	NAT13	1
NM_032012	C9orf5	1
NM_001099734		1
NM_016532	SKIP	1
NM_130766	SKIP	1
NM_014953	DIS3	1
NM_004852	ONECUT2	1
NM_002310	LIFR	1
NM_015200	SCC-112	1
NM_001100399		1
NM_175709	CBX7	1
NM_002713	PPP1R8	1
NM_014110	PPP1R8	1
NM_138558	PPP1R8	1
NM_152365	C1orf172	1
NM_130438	DYRK1A	1
NM_101395	DYRK1A	1
NM_130436	DYRK1A	1
NM_001396	DYRK1A	1
NM_130437	DYRK1A	1
NM_015026	MON2	1
NM_020823		1
NM_001100624		1
NM_024900	PHF17	1
NM_001040665	STEAP2	1
NM_152999	STEAP2	1
NM_145655	GCNT2	1
NM_145649	GCNT2	1
NM_001491	GCNT2	1
NM_006361	HOXB13	1
NM_020148	SPIRE1	1
NM_001039618	CREBZF	1
NM_020709		1
NM_001025233	CLLU1	1
NM_201648	GLYAT	1
NM_020429	SMURF1	1
NM_181349	SMURF1	1
NM_004097	EMX1	1
NM_003994	KITLG	1
NM_000899	KITLG	1
NM_214711	LOC401137	1
NM_030625	CXXC6	1
NM_030627	CPEB4	1
NM_018374	TMEM106B	1
NM_018225	SMU1	1
NM_015449	C1orf43	1
NM_001098616		1
NM_138740	C1orf43	1
NM_014807	TMEM24	1
NM_014397	NEK6	1
NM_145056	DACT3	1
NM_014898	ZFP30	1
NM_133458	ZFP90	1
NM_015392	NPDC1	1
NM_138771	CCDC126	1
NM_032717	MAG1	1
NM_004956	ETV1	1
NM_017919	STX17	1
NM_003882	WISP1	1
NM_003804	RIPK1	1
NM_004747	DLG5	1
NM_020774	MIB1	1
NM_021961	TEAD1	1
NM_014867	KBTBD11	1
NM_001025108	AFF3	1
NM_002285	AFF3	1
NM_001006657	WDR35	1
NM_020779	WDR35	1
NM_032105	PPP1R12B	1
NM_002481	PPP1R12B	1
NM_138287	DTX3L	1
NM_017506	OR7A5	1
NM_006546	IGF2BP1	1
NM_022341	PDF	1
NM_032382	COG8	1
NM_138621	BCL2L11	1
NM_006538	BCL2L11	1
XM_944366	LOC375295	1
XM_374020	LOC375295	1
XM_001130884	LOC729639	1
XM_001130664	LOC731756	1
NM_152753	SCUBE3	1
NM_016604	JMJD1B	1
NM_016018	PHF20L1	1
NM_016474	C3orf19	1
NM_014772	KIAA0427	1
NM_004748	CCPG1	1
NM_020739	CCPG1	1
NM_032737	LMNB2	1
NM_001005404	YPEL2	1
NM_181785	SLC46A3	1
NM_023073	FLJ13231	1
XM_001129292	MBOAT2	1
NM_007185	TNRC4	1
NM_006920	SCN1A	1
NM_003391	WNT2	1
NM_001310	CREBL2	1
NM_003909	CPNE3	1
NM_213645	WARS	1
NM_004184	WARS	1
NM_173701	WARS	1
NM_213646	WARS	1
NM_001010000	ARHGAP28	1
NM_005056	JARID1A	1
NM_001042603	JARID1A	1
NM_016121	KCTD3	1
NM_014624	S100A6	1
NM_001039840	CHIC1	1
NM_014160	MKRN2	1
NM_001010887	ASAH3L	1
NM_005837	POP7	1
NM_013255	MKLN1	1
NM_138774	C19orf22	1
NM_025047	ARL14	1
NM_002099	GYPA	1
NM_019593	KIAA1434	1
NM_017877	C2orf18	1
NM_030641	APOL6	1
XM_001127975	FAM66C	1
NM_014220	TM4SF1	1
NM_152407	GRPEL2	1
NM_145006	SUSD3	1
NM_021214		1
NM_207422	FLJ44635	1
NM_001102406		1
NM_025144	ALPK1	1
NM_003189	TAL1	1
NM_021216	ZNF71	1
NM_012334	MYO10	1
NM_004109	FDX1	1
NM_009589	ARSD	1
NM_001017440	CALN1	1
NM_031468	CALN1	1
XM_001128847	LOC728942	1
XM_001131211	LOC731906	1
NM_006298	ZNF192	1
NM_145251	STYX	1
XM_001125680	LOC730432	1
XM_001125705	LOC730432	1
NM_024894	NOL10	1
NM_032822	FLJ14668	1
XM_001129423	LOC729137	1
XM_001126090	LOC728146	1
XM_001129476	LOC286434	1
NM_001102559		1
NM_002830	PTPN4	1
NM_138281	DLX4	1
NM_001934	DLX4	1
NM_015207		1
NM_014849	SV2A	1
NM_031417	MARK4	1
NM_007195	POLI	1
NM_004896	VPS26A	1
NM_001035260	VPS26A	1
NM_152787	MAP3K7IP3	1
NM_080546	SLC44A1	1
NM_145799	SEPT6	1
NM_002661	PLCG2	1
NM_001110781		1
NM_000460	THPO	1
NM_018427	RRN3	1
NM_005915	MCM6	1
NM_015202	KIAA0556	1
NM_001017992	DKFZp686D0972	1
NM_001099287		1
NM_012281	KCND2	1
NM_181356	SUPT3H	1
NM_153183	NUDT10	1
NM_031203	HNRPM	1
NM_005968	HNRPM	1
NM_019558	HOXD8	1
NM_016468	C14orf112	1
NM_004090	DUSP3	1
NM_020962	NOPE	1
NM_001039591	USP9X	1
NM_001039590	USP9X	1
NM_004071	CLK1	1
NM_004936	CDKN2B	1
NM_078487	CDKN2B	1
NM_003288	TPD52L2	1
NM_199359	TPD52L2	1
NM_199362	TPD52L2	1
NM_199360	TPD52L2	1
NM_199363	TPD52L2	1
NM_199361	TPD52L2	1
NM_032626	RBBP6	1
NM_018323	PI4K2B	1
NM_016033	FAM82B	1
NM_007137	ZNF81	1
NM_020918	GPAM	1
NM_178425	HDAC9	1
NM_178423	HDAC9	1
NM_144571	CNOT6L	1
NM_006033	LIPG	1
NM_170692	RASAL2	1
NM_004841	RASAL2	1
NM_004657	SDPR	1
NM_144664	FAM76B	1
NM_017563	IL17RD	1
NM_001080973	IL17RD	1
NM_001085377		1
NM_002387	MCC	1
NM_001098213		1
NM_001098212		1
NM_000861	HRH1	1
NM_001098211		1
NM_024927	PLEKHH3	1
NM_015323	KIAA0776	1
NM_001102608		1
NM_000330	RS1	1
NM_014832	TBC1D4	1
NM_005068	SIM1	1
NM_020459		1
NM_033389	SSH2	1
NM_000912	OPRK1	1
NM_199413	PRC1	1
NM_199414	PRC1	1
NM_003981	PRC1	1
NM_181701	QSOX2	1
NM_004136	IREB2	1
NM_001004441	DP58	1
NM_152519	FLJ23861	1
NM_001482	GATM	1
NM_006420	ARFGEF2	1
NM_007269	STXBP3	1
NM_031284	ADPGK	1
NM_015265	SATB2	1
NM_007236	CHP	1
XM_001134344	FLJ37453	1
NM_001908	CTSB	1
NM_147781	CTSB	1
NM_147783	CTSB	1
NM_147780	CTSB	1
NM_147782	CTSB	1
NM_000318	PXMP3	1
NM_001079867	PXMP3	1
NM_182762	7A5	1
NM_173462	PAPLN	1
NM_014056	HIGD1A	1
NM_001099668		1
NM_001099669		1
XM_496826	NHSL1	1
XM_941807	NHSL1	1
NM_001043352	TPM3	1
NM_001043353	TPM3	1
NM_153649	TPM3	1
NM_001043351	TPM3	1
NM_000953	PTGDR	1
XM_001130518	LOC728485	1
XM_001133894	LOC731964	1
NM_207333	ZNF320	1
NM_001008801	ZNF468	1
NM_199132	ZNF468	1
NM_024947	PHC3	1
NM_017723	C9orf167	1
NM_207171	POGZ	1
NM_015100	POGZ	1
NM_017684	VPS13C	1
NM_020821	VPS13C	1

---

Immunostimulatory motif search results

UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).

---

---

Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

Parameter	Spec. Score cut-off	Colour	Comment
Hit to same gene		Colour	Hits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit	≥80	Colour	Hits are very likely to cause an off-target effect
Medium scoring hit	<80¸≥40	Colour	Hits with a small chance of causing an off target effect.
Low scoring hit		Colour	Hits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-off	Colour
Match	Colour
Wobble base pairs (G-U)	Colour
Critical bases (none)	Colour
0.6 bits	Colour
0.4 bits	Colour
0.2 bits	Colour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer

For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317