Predicted Off-targets for siRNA "ggcccggauggucauuuaa" Using siRNA SpecificityServer

Specificity Server [Result page v1.0]


SpecificityServer - An siRNA design program for determining siRNA specificity

Automatic recommendation
OK - siRNA is specific for both sense and antisense (guide) strands

7 hits were found for GGCCCGGAUGGUCAUUUAA (7 guide strand hits and 0 sense strand hits.)

Hits to Guide strand

AccessionGeneStartEndDetails of mismatchesSpec.
Score
MismatchesContiguousJackson style
specificity
Hits similar
gene
HSP
Score
HSP %
Identity
HSP lengthGene Length
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
NM_006295 VARS 2913 2931 GGCCCGGAUGGUCAUgcug42 4 15 c false   <90%   4308
NM_030668 PTPRO 1688 1706 GGCCCuGAUGGUCAUUUuu29 3 11 c false   <90%   2948
NM_030669 PTPRO 1772 1790 GGCCCuGAUGGUCAUUUuu29 3 11 c false   <90%   3032
NM_030670 PTPRO 2720 2738 GGCCCuGAUGGUCAUUUuu29 3 11 c false   <90%   3980
NM_030671 PTPRO 2804 2822 GGCCCuGAUGGUCAUUUuu29 3 11 c false   <90%   4064
NM_002848 PTPRO 3809 3827 GGCCCuGAUGGUCAUUUuu29 3 11 c false   <90%   5069
NM_030667 PTPRO 3893 3911 GGCCCuGAUGGUCAUUUuu29 3 11 c false   <90%   5153



3 prime UTR Seed matches

Hits to same gene : 0
Hits to other genes : 1126
View matched accessions

3 prime seed match details

AccessionGene nameHits to this gene
NM_032515BOK14
NM_000068CACNA1A6
NM_033129SCRT23
NM_014732KIAA05133
NM_002309LIF3
NM_182924MICALL23
NM_023067FOXL23
NM_004051BDH13
NM_203315BDH13
NM_203314BDH13
NM_020956PRX3
NM_000278PAX23
NM_003989PAX23
NM_003990PAX23
NM_003987PAX23
NM_003988PAX23
NM_006160NEUROD23
NM_000744CHRNA43
NM_001042535CENTG33
NM_015417C20orf283
NM_172367TUSC53
XM_932244LOC6531603
XM_945233LOC6531603
NM_145175FAM84A3
NM_173476CCDC783
NM_194457UBE2J22
NM_194315UBE2J22
NM_058167UBE2J22
NM_194458UBE2J22
NM_005312RAPGEF12
NM_198679RAPGEF12
NM_014275MGAT4B2
NM_054013MGAT4B2
NM_020814MARCH42
NM_020713ZNF512B2
NM_153254TTLL102
NM_207348SLC25A342
NM_015042ZNF6092
NM_033446FAM125B2
XM_001125737LOC7302752
NM_000719CACNA1C2
NM_015166MLC12
NM_139202MLC12
XM_001129116MGC396062
XM_001127817MGC396062
NM_006676USP202
NM_001005361DNM22
NM_004945DNM22
NM_001005362DNM22
NM_001005360DNM22
NM_177457LYNX12
NM_177477LYNX12
NM_177476LYNX12
NM_018941CLN82
NM_182923KLC12
NM_015113ZZEF12
NM_058238WNT7B2
NM_004227PSCD32
NM_001024401SBK12
NM_031904FKSG442
NM_024676C1orf1132
NM_001025100MBP2
NM_017649CNNM22
NM_199076CNNM22
NM_080647TBX12
NM_001754RUNX12
NM_001001890RUNX12
NM_020795NLGN22
NM_002737PRKCA2
NM_207419C1QTNF82
XM_001133002LOC7288042
NM_001702BAI12
NM_003029SHC12
NM_052847GNG72
XM_001130546LOC7295422
NM_020477ANK12
NM_020475ANK12
NM_000037ANK12
NM_020476ANK12
NM_020478ANK12
NM_020480ANK12
NM_024329EFHD22
NM_020211RGMA2
NM_033131WNT3A2
NM_0011055792
NM_015104KIAA04042
NM_032843FIBCD12
NM_174892CD300LB2
NM_032569N-PAC2
NM_032242PLXNA12
NM_001001795MGC708572
NM_080605B3GALT62
NM_031918KLF162
NM_001001502SNCB2
NM_003085SNCB2
NM_004822NTN12
NM_001004354MGC615982
NM_014700RAB11FIP32
XM_001130364LOC7284172
XM_001130184LOC7308432
NM_001079843CASZ12
NM_133452RAVER12
NM_175895C12orf612
NM_023931ZNF7472
NM_000376VDR2
NM_001017535VDR2
XM_379029LOC4008792
XM_001130582LOC7283922
XM_001132379LOC7309942
NM_006076HRBL2
XM_001131019LOC7318462
XM_001131201LOC7297512
NM_014370SRPK32
NM_006927ST3GAL22
NM_017450BAIAP22
NM_020429SMURF12
NM_181349SMURF12
NM_153029N4BP12
NM_025251KIAA16882
NM_014898ZFP302
NM_020440PTGFRN2
NM_015557CHD52
NM_001013693LDLRAD22
NM_001008701LPHN12
NM_014921LPHN12
NM_006795EHD12
NM_020764CASKIN12
NM_014228SLC6A72
NM_021025TLX32
NM_001082575HRNBP32
NM_000961PTGIS2
NM_014286FREQ2
NM_001042371LOC2838712
NM_001001791C10orf552
NM_032108SEMA6B2
NM_001810CENPB2
NM_017712PGPEP12
NM_001079877RASA42
NM_006989RASA42
NM_004296RGS62
NM_002149HPCAL12
NM_134421HPCAL12
NM_005730CTDSP21
NM_004230EDG51
NM_001328CTBP11
NM_001012614CTBP11
NM_000439PCSK11
XM_373690LOC3882821
XM_001133719LOC3882821
NM_014646LPIN21
NM_001001557GDF61
NM_004302ACVR1B1
NM_0010992701
NM_001040659TTC231
NM_001040656TTC231
NM_001040658TTC231
NM_022905TTC231
NM_001040657TTC231
NM_001040655TTC231
NM_001040660TTC231
NM_015082FSTL41
NM_005928MFGE81
NM_001083536FGD31
NM_033086FGD31
NM_144767AKAP131
NM_006738AKAP131
NM_007200AKAP131
XM_931016LOC3880761
NM_021991JUP1
NM_002230JUP1
NM_181670ANKS1B1
NM_000021PSEN11
NM_173681ATG9B1
NM_001008723C10orf801
NM_015278SASH11
NM_007033RER11
NM_030818CCDC1301
NM_003120SPI11
NM_001080547SPI11
NM_178520TMEM1051
NM_004943DMWD1
NM_006764IFRD21
NM_001406EFNB31
NM_198559MGC508111
NM_002209ITGAL1
NM_181458PAX31
NM_181460PAX31
NM_181457PAX31
NM_181459PAX31
NM_024722ACBD41
NM_006593TBR11
NM_080825C20orf1441
NM_020064BARHL11
NM_0011016541
NM_014593CXXC11
NM_145045MGC209831
NM_004189SOX141
NM_004729ZBED11
NM_009588LTB1
NM_002341LTB1
NM_007185TNRC41
NM_022119PRSS221
NM_000683ADRA2C1
NM_025248SNIP1
XM_001128242LOC7287041
XM_001128273LOC7287191
NM_001005920LOC3391231
NM_153229TMEM921
NM_174968ST3GAL31
NM_174971ST3GAL31
NM_174964ST3GAL31
NM_174963ST3GAL31
NM_174969ST3GAL31
NM_174965ST3GAL31
NM_174966ST3GAL31
NM_174970ST3GAL31
NM_006279ST3GAL31
NM_174967ST3GAL31
NM_005461MAFB1
NM_000216KAL11
NM_017828COMMD41
NM_001080825LOC1444041
NM_003486SLC7A51
NM_002390ADAM111
NM_003028SHB1
NM_024100WDR181
NM_005105RBM8A1
NM_198973MKNK11
NM_001024843TNRC6B1
NM_015088TNRC6B1
NM_004907IER21
NM_001924GADD45A1
NM_032251CCDC881
NM_031882PCDHAC11
NM_022153C10orf541
NM_152326ANKRD91
NM_138802ZFAND2B1
NM_001039966GPR301
NM_001505GPR301
NM_0010982011
NM_020145SH3GLB21
XM_001129825LOC7288171
XM_001129242LOC7311711
NM_152237GAS2L11
NM_001782CD721
NM_014460CSDC21
NM_0011110191
NM_145117NAV21
NM_182964NAV21
NM_0011110181
NM_015553PIP3-E1
NM_0011103031
NM_001008563USP201
NM_015720PODXL21
NM_015194MYO1D1
XM_001133756LOC7316011
XM_001133752LOC7294301
NM_007024TMEM1151
NM_003636KCNAB21
NM_172130KCNAB21
NM_005195CEBPD1
NM_016170TLX21
NM_003438ZNF1371
NM_003482MLL21
NM_145805ISL21
NM_000215JAK31
NM_007078LDB31
NM_001080114LDB31
NM_019074DLL41
NM_173477USH1G1
NM_145003TSNARE11
NM_014757MAML11
XM_001126853MAML11
NM_133330WHSC11
NM_001042424WHSC11
NM_133331WHSC11
NM_133335WHSC11
NM_0010096101
NM_001348DAPK31
NM_020708SLC12A51
NM_199141CARM11
XM_928464LOC1465171
NM_018942HMX11
NM_015219EXOC71
NM_001013839EXOC71
NM_019594LRRC8A1
NM_206965FTCD1
NM_001001412FAM26C1
NM_014587SOX81
NM_003223TFAP41
NM_139012MAPK141
NM_139014MAPK141
NM_001315MAPK141
NM_030891LRRC31
NM_024742ARMC51
NM_001040445ASB11
NM_001042574CRTC31
NM_022769CRTC31
NM_199332HOMER21
NM_004839HOMER21
NM_199331HOMER21
NM_199330HOMER21
NM_000148FUT11
NM_032296FLYWCH11
NM_002250KCNN41
NM_003458BSN1
NM_153442GPR261
NM_197941ADAMTS61
NM_004955SLC29A11
NM_001078176SLC29A11
NM_001078175SLC29A11
NM_001078177SLC29A11
NM_001078174SLC29A11
NM_181050AXIN11
NM_003502AXIN11
NM_001275CHGA1
NM_015321CRTC11
NM_0010984821
NM_020385REXO41
NM_002217ITIH31
NM_015393DKFZP564O08231
NM_020896OSBPL51
NM_145638OSBPL51
NM_014506TOR1B1
NM_207327LOC1503831
NM_006668CYP46A11
NM_000918P4HB1
NM_0154731
NM_018059FLJ103241
NM_182688UBE2G21
NM_003343UBE2G21
NM_133467CITED41
NM_014851KLHL211
NM_014867KBTBD111
NM_001038633RSPO11
NM_020382SETD81
NM_014694ADAMTSL21
NM_005076CNTN21
NM_021996GBGT11
NM_004205USP21
NM_002292LAMB21
NM_182925FLT41
NM_015124DIP1
NM_152777C14orf481
NM_024513FYCO11
NM_001007279RASL10A1
NM_003907EIF2B51
NM_172251MRPL541
NM_014470RND11
NM_147196TMIE1
NM_002103GYS11
NM_203327SLC23A21
NM_005116SLC23A21
NM_130848C5orf201
NM_148672CCL281
NM_021181SLAMF71
NM_006671SLC1A71
NM_001561TNFRSF91
NM_006858TMED11
NM_004104FASN1
NM_000156GAMT1
NM_006767LZTR11
NM_033410ZNF7641
NM_020132AGPAT31
NM_001037553AGPAT31
NM_001004353LOC4414761
XM_001134399LOC7302571
NM_002193INHBB1
NM_133465KIAA19581
NM_025236RNF391
NM_170769RNF391
NM_014337PPIL21
NM_001044370MPPED11
NM_178003PPP2R41
NM_021131PPP2R41
NM_178000PPP2R41
NM_178001PPP2R41
NM_013443ST6GALNAC61
NM_022463NXN1
NM_030815PDRG11
NM_001409MEGF61
NM_139159DPP91
NM_001760CCND31
NM_207311CCDC641
NM_198582KLHL301
NM_022123NPAS31
NM_004647DPF11
NM_024104C19orf421
NM_001687ATP5D1
XM_001129019SAPS21
NM_181489ZNF4451
NM_001008404LOC4002581
NM_003152STAT5A1
NM_198488FAM83H1
NM_144985CDH241
NM_022478CDH241
NM_194460RNF1261
NM_007327GRIN11
NM_021569GRIN11
NM_002359MAFG1
NM_032711MAFG1
NM_003025SH3GL11
NM_005072SLC12A41
XM_928029RNF1871
XM_001129309RNF1871
NM_024090ELOVL61
NM_022896LPIN31
NM_001445FABP61
NM_001040442FABP61
NM_001006616TSPAN171
NM_000660TGFB11
NM_014360NKX2-81
NM_006005WFS11
NM_001018050POLR3H1
NM_138338POLR3H1
NM_001018052POLR3H1
NM_144645C4orf361
NM_079837BANP1
NM_017869BANP1
NM_001711BGN1
XM_941762SETD1B1
XM_037523SETD1B1
NM_001958EEF1A21
NM_001194HCN21
NM_183413FBXO441
NM_033182FBXO441
NM_001014765FBXO441
NM_183412FBXO441
NM_005515HLXB91
NM_000180GUCY2D1
NM_018389SLC35C11
NM_181079IL21R1
NM_021798IL21R1
NM_181078IL21R1
NM_006640SEPT91
NM_016176SDF41
NM_016547SDF41
NM_012121CDC42EP41
NM_178554KY1
NM_002442MSI11
NM_004884PUNC1
NM_015254KIF13B1
XM_941783JMJD31
NM_001080424JMJD31
NM_018953HOXC51
NM_018198DNAJC111
NM_004981KCNJ41
NM_152868KCNJ41
NM_002856PVRL21
NM_018645HES61
NM_016564CEND11
NM_001039570KREMEN11
NM_001039571KREMEN11
NM_005632SOLH1
NM_001026213CYP11B11
NM_000497CYP11B11
NM_004565PEX141
NM_001003704MTP181
NM_016498MTP181
NM_002653PITX11
NM_001029835CCM21
NM_031443CCM21
XM_001133948LOC7318551
NM_014231VAMP11
NM_199245VAMP11
NM_014577BRD11
XM_001134414C1orf1331
XM_001134416C1orf1331
NM_005618DLL11
NM_021267LASS11
XM_930678LOC6424411
XM_001134398LOC7302561
NM_000455STK111
NM_014994MAPKBP11
NM_152643KNDC11
NM_152299NCAPH21
NM_006099PIAS31
NM_152449LYSMD41
NM_001031738TMEM1501
NM_153342TMEM1501
NM_003635NDST21
NM_198576AGRN1
XM_001126326AGRIN1
NM_138983OLIG11
NM_145260OSR11
NM_014957DENND31
NM_052813CARD91
NM_025204TRABD1
XM_379273FLJ141861
NM_022162NOD21
NM_152988SPPL2B1
NM_001077238SPPL2B1
NM_001079514UBN11
NM_016936UBN11
NM_020895GRAMD1A1
XM_001132233LOC7300531
NM_002900RBP31
NM_144775SMCR81
NM_016111TELO21
NM_001319CSNK1G21
NM_153693HOXC61
NM_004503HOXC61
XM_933796SLC45A41
NM_022720DGCR81
NM_004737LARGE1
NM_133642LARGE1
NM_022834VWA11
NM_199121VWA11
NM_198580SLC27A11
NM_207335KLHDC61
NM_001017916CYB5611
NM_001915CYB5611
NM_001017917CYB5611
NM_018006TRMU1
NM_145245EVI5L1
NM_003072SMARCA41
NM_012453TBL21
NM_005883APC21
NM_021619PRDM121
NM_004455EXTL11
NM_173484KLF171
NM_000684ADRB11
XM_001130790KIAA18811
NM_001080400KIAA18811
NM_017909RMND11
XM_943043LOC6539041
NM_017856GEMIN81
NM_001042479GEMIN81
NM_001042480GEMIN81
XM_001127568LOC7284991
XM_001127665LOC7285261
XM_001130826LOC7284521
XM_001127715LOC7285401
XM_001127825LOC7285751
XM_001130837LOC6433671
NM_207111TRIAD31
NM_207116TRIAD31
XM_001134324LOC7322871
XM_001131719LOC7285851
NM_000875IGF1R1
NM_003313TSTA31
XM_001130627LOC7295591
NM_017899TESC1
NM_014706SART31
NM_145298APOBEC3F1
NM_021817HAPLN21
NM_153265EML31
NM_000017ACADS1
NM_206833CTXN11
NM_015604WDR21A1
NM_181340WDR21A1
NM_181341WDR21A1
NM_015305ANGEL11
NM_014844KIAA03291
NM_032642WNT5B1
NM_030775WNT5B1
NM_002714PPP1R101
NM_021962ABR1
NM_001092ABR1
NM_153675FOXA21
NM_021784FOXA21
NM_152458ZNF7851
NM_021155CD2091
NM_000554CRX1
NM_173214NFAT51
NM_006599NFAT51
NM_138714NFAT51
NM_0011131781
NM_138713NFAT51
NM_004953EIF4G11
NM_198244EIF4G11
NM_198241EIF4G11
NM_198242EIF4G11
NM_182917EIF4G11
NM_002843PTPRJ1
NM_003288TPD52L21
NM_199359TPD52L21
NM_199362TPD52L21
NM_199360TPD52L21
NM_199363TPD52L21
NM_199361TPD52L21
NM_147187TNFRSF10B1
NM_003842TNFRSF10B1
NM_001010855C17orf381
NM_012398PIP5K1C1
NM_014564LHX31
NM_178138LHX31
NM_014240LIMD11
NM_000246CIITA1
NM_013373ZDHHC81
NM_003221TFAP2B1
NM_002883RANGAP11
NM_001040439MAPK8IP31
NM_015133MAPK8IP31
NM_006091CORO2B1
NM_024015HOXB41
NM_001012264RNASE131
NM_198318PRMT11
NM_198319PRMT11
NM_001536PRMT11
NM_020761KIAA13031
NM_002517NPAS11
NM_004339PTTG1IP1
NM_153636CPNE71
NM_014427CPNE71
NM_148571MRPL271
NM_015892GALNAC4S-6ST1
NM_207006FAM83A1
NM_014141CNTNAP21
NM_178557NAT8L1
NM_024016HOXB81
NM_003382VIPR21
XM_001131395LOC7298101
XM_001126629LOC7306341
NM_175747OLIG31
NM_033317DMKN1
NM_001035516DMKN1
NM_001001480KRTAP5-51
NM_016643ZNF7711
NM_001002295GATA31
NM_002051GATA31
NM_032102SFRS2B1
NM_058192RPUSD11
NM_021147CCNU1
NM_000831GRIK31
NM_002531NTSR11
NM_020714ZNF4901
NM_002957RXRA1
NM_007219RNF241
NM_015227POFUT21
NM_133634POFUT21
NM_133635POFUT21
XM_928834LOC6458511
XM_940488LOC6458511
NM_007232HRH31
NM_054016FUSIP11
XM_001126406LOC7279221
XM_001126391LOC7279221
XM_001126417LOC7279221
NM_003255TIMP21
XM_001132362TIMP21
NM_198581ZC3H61
NM_138418C16orf141
NM_002918RFX11
NM_206967C16orf741
NM_033119NKD11
NM_015379BRI31
NM_032309CHCHD51
NM_033260FOXQ11
NM_003018SFTPC1
NM_139058ARX1
NM_178275DKFZp434B12311
NM_017902HIF1AN1
NM_152942TNFRSF81
NM_001243TNFRSF81
NM_002917RFNG1
XM_001132711RFNG1
NM_003839TNFRSF11A1
NM_002284KRT861
NM_181351NCAM11
NM_000615NCAM11
NM_001004358FGFRL11
NM_021923FGFRL11
NM_001004356FGFRL11
NM_015174KIAA10861
NM_144498OSBPL21
NM_014835OSBPL21
NM_013364PNMA31
NM_173728ARHGEF151
NM_015894STMN31
NM_177536SULT1A11
NM_177534SULT1A11
NM_177530SULT1A11
NM_001055SULT1A11
NM_177529SULT1A11
NM_014830ZBTB391
NM_001189BAPX11
NM_170607MLX1
NM_198204MLX1
NM_198205MLX1
NM_001031734MGC196041
NM_017436A4GALT1
NM_023035CACNA1A1
NM_014697NOS1AP1
NM_001004304ZNF7401
NM_002735PRKAR1B1
NM_017521FEV1
XM_373497LOC3877631
XM_941665LOC3877631
NM_017957EPN31
NM_003612SEMA7A1
NM_014246CELSR11
XM_001126125PGAM51
NM_021615CHST61
NM_000738CHRM11
NM_138734NRXN21
NM_015080NRXN21
NM_138732NRXN21
NM_207391RGS9BP1
NM_017596KIF21B1
NM_012306FAIM21
NM_0151751
NM_0179501
NM_032329ING51
XM_941026ING51
XM_001126273LOC7277731
NM_020904PLEKHA41
NM_006351TIMM441
NM_022772EPS8L21
XM_001129221EPS8L21
NM_152371C1orf931
NM_007014WWP21
NM_199424WWP21
NM_198493ANKRD451
NM_020845PITPNM21
NM_013286RBM15B1
NM_001031680RUNX31
NM_004350RUNX31
NM_001040661SLC29A41
NM_153247SLC29A41
XM_379840LOC4025091
XM_935781LOC4025091
NM_152568NKX6-31
NM_032298SYT31
NM_014755SERTAD21
NM_014807TMEM241
NM_016178OAZ31
NM_004132HABP21
NM_144991C21orf291
NM_031954KCTD101
NM_007030TPPP1
NM_000478ALPL1
NM_001037165FOXK11
NM_000629IFNAR11
NM_001031717CRELD11
NM_001077415CRELD11
NM_015513CRELD11
NM_144691CAPN121
NM_001083112GPD21
NM_000408GPD21
NM_177963SYT121
NM_004693KRT751
NM_001033582PRKCZ1
NM_002744PRKCZ1
NM_001033581PRKCZ1
NM_181804PKIG1
NM_181805PKIG1
NM_007066PKIG1
NM_0010992721
NM_152733BTBD91
NM_0528931
NM_018667SMPD31
NM_030971SFXN31
NM_198098AQP11
NM_173492PIP5KL11
NM_001042633SNX211
NM_001042632SNX211
NM_014924KIAA08311
NM_024704C20orf231
NM_001012427FOXP41
NM_138457FOXP41
NM_001012426FOXP41
NM_024653PRKRIP11
XM_372194C1orf1701
XM_936696C1orf1701
NM_030665RAI11
NM_030758OSBP21
NM_001039360ZBTB7C1
NM_018026PACS11
NM_002473MYH91
NM_139161CRB31
NM_004003CRAT1
NM_000755CRAT1
NM_002688SEPT51
XM_940825DLGAP31
NM_001080418DLGAP31
NM_004204PIGQ1
NM_152913TMEM1301
NM_001852COL9A21
NM_015078MCF2L21
NM_017456PSCD11
NM_004762PSCD11
NM_181552CUTL11
NM_003764STX111
NM_023078PYCRL1
NM_002501NFIX1
NM_015381FAM19A51
NM_001082967FAM19A51
NM_014714IFT1401
NM_133371MYOZ31
NM_001042486DLGAP41
NM_014902DLGAP41
NM_183006DLGAP41
NM_001842CNTFR1
NM_147164CNTFR1
NM_004273CHST31
XM_936244LOC6538851
NM_000820GAS61
NM_152384BBS51
XM_001131828BBS51
XM_001131846BBS51
XM_001127981LOC7280141
NM_003959HIP1R1
NM_014850SRGAP31
NM_001033117SRGAP31
NM_181705LYRM71
XM_497110LOC4414951
XM_372214LOC3898571
XM_938184LOC3898571
XM_001126137LOC2849521
XM_001129340LOC2849521
NM_003924PHOX2B1
NM_174953ATP2A31
NM_174956ATP2A31
NM_174954ATP2A31
NM_174957ATP2A31
NM_174958ATP2A31
NM_005173ATP2A31
NM_174955ATP2A31
NM_023008FLJ129491
NM_015722DRD1IP1
NM_017891C1orf1591
NM_199461NANOS11
NM_014723SNPH1
NM_052926PNMA51
NM_0011031511
NM_0011031501
NM_024599RHBDF21
NM_001005498RHBDF21
NM_006464TGOLN21
NM_002360MAFK1
NM_001007139IGF21
NM_000612IGF21
NM_212533ABCA21
NM_001606ABCA21
NM_015178RHOBTB21
NM_030767AKNA1
NM_032127C11orf561
NM_0010987941
NM_020947KIAA16091
NM_205854SFTPG1
NM_002342LTBR1
NM_020822KCNT11
NM_0010988161
NM_032809FAM73B1
NM_183048ZMYND81
NM_183047ZMYND81
NM_012408ZMYND81
NM_015259ICOSLG1
NM_004321KIF1A1
XM_932840FBF11
XM_946193FBF11
XM_371079FBF11
XM_942657FBF11
NM_173465COL23A11
NM_153832GPR1611
NM_001005407CACNA1H1
NM_021098CACNA1H1
NM_020170NCLN1
XM_001131068LOC7296961
XM_001129643LOC7314351
NM_001034914KCNIP31
NM_013434KCNIP31
NM_018028SAMD4B1
NM_005313PDIA31
NM_012458TIMM131
NM_014230SRP681
NM_198560LHFPL41
NM_018998FBXW51
NM_032737LMNB21
NM_080607C20orf1021
NM_015627LDLRAP11
NM_080625C20orf1601
NM_014638PLCH21
NM_020777SORCS21
NM_003021SGTA1
NM_020184CNNM41
NM_002073GNAZ1
NM_000476AK11
NM_024036LRFN41
NM_173527REM21
NM_005458GABBR21
NM_052838SEPT11
XM_001132049SEPT11
NM_0010986321
NM_032375AKT1S11
NM_0010986331
NM_002070GNAI21
NM_002307LGALS71
NM_001042507LOC6534991
XM_001128786LOC7289101
XM_001133982LOC7320321
XM_001132650LOC1494781
XM_001128950LOC1494781
NM_199262SP61
NM_002978SCNN1D1
NM_004474FOXD21
NM_006801KDELR11
NM_020062SLC2A4RG1
NM_005018PDCD11
NM_024652LRRK11
NM_171982TRIM351
NM_017966VPS37C1
NM_001080484KIAA17511
XM_936307KIAA17511
NM_015197PACS21
NM_0011009131
NM_001047SRD5A11
NM_152722HEPACAM1
NM_001014764TMEM931
NM_031298TMEM931
NM_001013706LSDP51
XM_001130043LOC4405031
XM_001130801LOC4405031
NM_014690FAM131B1
NM_001031690FAM131B1
NM_019034RHOF1
NM_187841TRIM541
NM_032546TRIM541
NM_178835LOC1524851
NM_183240TMEM371
NM_033630SCAND11
NM_016558SCAND11
NM_014516CNOT31
NM_032854CORO61
NM_022470ZMAT31
NM_152240ZMAT31
NM_001830CLCN41
NM_033229TRIM151
NM_178122C1orf2011
NM_000527LDLR1
NM_198236ARHGEF111
NM_014784ARHGEF111
NM_147161ACOT111
NM_000721CACNA1E1
NM_002414CD991
NM_001002836ZNF7871
XM_001130325LOC7284691
XM_001132990LOC7314481
NM_080669SLC46A11
NM_007065CDC371
NM_031476CRISPLD21
XM_938287LOC6539301
XM_001129280LOC7290861
NM_030796ECOP1
NM_032656DHX371
XM_001129321LOC4005531
XM_001132183LOC4005531
NM_153021PLB11
NM_020971SPTBN41
NM_0011055651
XM_166203SMTNL11
NM_025216WNT10A1
NM_153498CAMK1D1
NM_017559FNDC81
NM_181709FAM101A1
NM_032137C3orf201
NM_024050C19orf581
NM_014634PPM1F1
NM_021806FAM3A1
NM_002730PRKACA1
NM_207518PRKACA1
NM_004560ROR21
NM_004957FPGS1
NM_001018078FPGS1
NM_198597SEC24C1
NM_004922SEC24C1
NM_002725PRELP1
NM_201348PRELP1
NM_004995MMP141
NM_005557KRT161
NM_004710SYNGR21
NM_001849COL6A21
NM_024029YIPF21
XM_937698LOC6486291
NM_178120DLX11
NM_001038493DLX11
NM_001031617COX191
NM_153048FYN1
NM_002037FYN1
NM_153047FYN1
NM_213605ZNF5171
NM_0010976201
NM_0010994091
NM_031910C1QTNF61
NM_182486C1QTNF61
NM_021116ADCY11
NM_005374MPP21
NM_001003406CACNA1I1
NM_021096CACNA1I1
NM_199454PRDM161
NM_022114PRDM161
XM_001133211LOC7290031
XM_001133556LOC7291351
NM_0207091
NM_031858NBR11
NM_031862NBR11
NM_005899NBR11
XM_001124828LOC7277321
NM_0011003981
NM_015085GARNL41
NM_014567BCAR11
NM_000555DCX1
NM_178152DCX1
NM_178153DCX1
NM_178151DCX1
NM_005672PSCA1
NM_020702KIAA11611
NM_207645LOC3999471
NM_198859PRICKLE21
NM_017851PARP161
NM_033025SYDE11
NM_024681KCTD171
NM_007144PCGF21
NM_138706B3GNT61
NM_031912SYT151
NM_015160PMPCA1
NM_005011NRF11
NM_001040110NRF11
NM_2073061
NM_000294PHKG21
XM_942831LOC4010741
NM_002151HPN1
NM_182983HPN1
XM_001127362KIAA05741
NM_031309SCRT11
NM_021808GALNT91
NM_005984SLC25A11
NM_199459C10orf711
NM_001970EIF5A1
NM_004359CDC341
XM_001133170LOC7288241
XM_001129120LOC7290341
XM_943193LOC4000271
XM_931434LOC4000271
NM_138774C19orf221
NM_130446KLHL61
NM_024674LIN281
NM_147192DMBX11
NM_172225DMBX11
NM_032536NTNG21
NM_001451FOXF11
NM_000196HSD11B21
XM_928905LOC6459371
XM_938329LOC6492671
NM_017949CUEDC11
NM_174940TMEM801
NM_001042463TMEM801
NM_032287LDOC1L1
NM_198388CACNA1G1
NM_198387CACNA1G1
NM_198396CACNA1G1
NM_198378CACNA1G1
NM_198379CACNA1G1
NM_198380CACNA1G1
NM_198382CACNA1G1
NM_198385CACNA1G1
NM_018896CACNA1G1
NM_198377CACNA1G1
NM_198386CACNA1G1
NM_198376CACNA1G1
NM_198384CACNA1G1
NM_198383CACNA1G1
NM_024309TNIP21
NM_178169RASSF31
NM_004584RAD9A1
NM_005491CXorf61
NM_016084RASD11
NM_001083600FLJ141541
NM_001083601FLJ141541
NM_024845FLJ141541
NM_015872ZBTB7B1
NM_001025077CUGBP21
NM_001362DIO31
NM_052906LRRC621
NM_018141MRPS101
NM_001620AHNAK1
XM_937358LOC6423841
XM_926149LOC6423841
NM_032853MUM11
NM_006705GADD45G1
XM_001129261LOC7290821
XM_001129056LOC7312731
NM_138450ARL111
NM_007042RPP141
NM_0010987831
NM_006734HIVEP21
NM_016270KLF21
NM_003897IER31
XM_933701LOC6441651
XM_001129467LOC7284681
NM_021574BCR1
NM_004327BCR1
NM_144671FAM109A1
NM_178129P2RY81
NM_022480KLHL251
NM_018043TMEM16A1
NM_005934MLLT11
XM_001131899LOC2839041
NM_178519C17orf551
NM_021168RAB40C1
NM_018015CXorf571
NM_1992871
NM_003043SLC6A61
NM_004535MYT11
NM_000877IL1R11
NM_001003656PPP2R2D1
NM_018461PPP2R2D1
NM_015898ZBTB7A1
NM_0011003901
NM_152558IQCE1
NM_031459SESN21
NM_016049C14orf1221
NM_014665LRRC141
NM_152281SCYL1BP11
NM_178172LOC3383281
NM_0010992201
NM_022773TMEM1121
NM_002033FUT41
NM_001277CHKA1
NM_212469CHKA1
NM_004522KIF5C1
NM_002547OPHN11
NM_003353UCN1
NM_007084SOX211
NM_001080113PP89611

Immunostimulatory motif search results


UGUGU - Judge et al. Sequence-dependent stimulation of the mammalian innate immune response by synthetic siRNA. Nat Biotechnol. 2005 Apr;23(4):457-62. (PMID: 15778705)
No Immunostimulatory motif found (UGUGU).

GUCCUUCAA - Hornung et al. Sequence-specific potent induction of IFN-alpha by short interfering RNA in plasmacytoid dendritic cells through TLR7. Nat Med. 2005 Mar;11(3):263-70. Epub 2005 Feb 20. (PMID: 15723075)
No Immunostimulatory motif found (GUCCUUCAA).



Settings used for search

Scores were calculated using scoring scheme SS1
Using AVG scoring mode.

Hit scores

ParameterSpec. Score cut-offColourComment
Hit to same geneColourHits to the same accession or genes with 100 percent identity (i.e. likely transcript variants). It is advisable to always check the genes hit.
High scoring hit≥80ColourHits are very likely to cause an off-target effect
Medium scoring hit<80¸≥40ColourHits with a small chance of causing an off target effect.
Low scoring hitColourHits very unlikely to cause an off-target effect

The mismatches are colour coded based on the weighting of that position.

Cut-offColour
MatchColour
Wobble base pairs (G-U)Colour
Critical bases (none)Colour
0.6 bitsColour
0.4 bitsColour
0.2 bitsColour

About SpecificityServer

SpecificityServer is designed to help you identify potential non-specific matches to your siRNA. It incorporates the latest information about non-specific matches (sequence-specific only).

Designed by: Alistair Chalk, Quan Du, Zicai Liang and Erik L.L. Sonnhammer


For more details about the algorithm "siRNA specificity searching incorporating mismatch tolerance data" Bioinformatics (2008) 24 (10): 1316-1317