Domain-domain interaction prediction server
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  • Some of the relevant sites and their usage are described below-

    Site NameDescriptionLink
    PFAMDatabase of protein domain familieshttp://pfam.sanger.ac.uk/
    3didDatabase of domain-domain interactionshttp://3did.irbbarcelona.org/cgi-bin/summary_cgi.pl
    Protein Data BankMacromolecular structure databasehttp://www.rcsb.org/pdb/home/home.do
    iPFAMProtein Domain Interactions Databasehttp://ipfam.sanger.ac.uk/
    DomainGraphDomainGraph is a Java plugin for Cytoscape, a software platform for the analysis and visualization of molecular interaction networkshttp://domaingraph.bioinf.mpi-inf.mpg.de/
    DDINetPredicted domain interactions using K-GIDDI's methods
    [Liu, M., X. W. Chen, et al. (2009). "Knowledge-guided inference of domain-domain interactions from incomplete protein-protein interaction networks." Bioinformatics 25(19): 2492-2499.]
    http://www.ittc.ku.edu/~xwchen/domainNetwork/ddinet.html
    DOMINEDOMINE is a database of known and predicted protein domain (domain-domain) interactionshttp://domine.utdallas.edu/cgi-bin/Domine
    Conserved Domains Database (CDD)CDD is a protein annotation resource that consists of a collection of well-annotated multiple sequence alignment models for ancient domains and full-length proteinshttp://www.ncbi.nlm.nih.gov/Structure/cdd/cdd.shtml
    InterDomInterDom is a database of putative interacting protein domains derived from multiple sources, ranging from domain fusions (Rosetta Stone), protein interactions (DIP and BIND), protein complexes (PDB), to scientific literature (MEDLINE). http://interdom.i2r.a-star.edu.sg/
    d-Omixa mixer of generic protein domain analysis toolshttp://www3a.biotec.or.th/Domix/
    InterProInterPro is an integrated database of predictive protein "signatures" used for the classification and automatic annotation of proteins and genomeshttp://www.ebi.ac.uk/interpro/