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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) GC Content (%) Cell line PubMed 1498 HIV-1 (NL4-3) AF324493 Env 628 CCAAUUCCCAUACAUUAUUG 31.80 28 HEK 293a 19497094 1185 HIV-1 (LAI) K02013 Pol/Vif 4625 GGAAAACAGAUGGCAGGUG 32.00 42 293 T 16959541 1180 HIV-1 (LAI) K02013 Pol 4544 GGUGAAGGGGCAGUAGUAA 32.00 42 293 T 16959541 1177 HIV-1 (LAI) K02013 Pol 4541 AAAGGUGAAGGGGCAGUAG 32.00 42 293 T 16959541 1148 HIV-1 (LAI) K02013 Pol 4360 CAAUUUUAAAAGAAAAGGG 32.00 21 293 T 16959541 1488 HIV-1 (NL4-3) AF324493 Vpu 140 AAAGAGCAGAAGACAGUGGCA 32.60 38 HEK 293a 19497094 1164 HIV-1 (LAI) K02013 Pol 4466 AAAAUUCAAAAUUUUCGGG 33.00 21 293 T 16959541 1145 HIV-1 (LAI) K02013 Pol 4233 UUCCCUACAAUCCCCAAAG 33.00 38 293 T 16959541 1222 HIV-1 (LAI) K02013 Pol 4393 CAGUGCAGGGGAAAGAAUA 33.00 38 293 T 17628029 1103 HIV-1 C K03455 Gag 1033 GUAGCAACUCUCUAUUGUGUA 33.00 31 HEK 293T 16706616 1054 HIV-1 (NL4-3) AF324493 Tat 5863 AAGCAUCCAGGAAGUCAGCCU 34.00 42 293 T 15564478 1044 HIV-1 (NL4-3) AF324493 Env N/A CACAATCACACTCCCATGCAG 35.00 42 293 T 15336659 1175 HIV-1 (LAI) K02013 Pol 4539 GGAAAGGUGAAGGGGCAGU 35.00 46 293 T 16959541 1173 HIV-1 (LAI) K02013 Pol 4537 CUGGAAAGGUGAAGGGGCA 35.00 46 293 T 16959541

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