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Page - 1 of 1 HIVsir ID HIV Strain NCBI Accession Target Gene Position of siRNA target Sense Sequence of siRNA Efficacy (%) Target Conservation * Cell line PubMed 1054 HIV-1 (NL4-3) AF324493 Tat 5863 AAGCAUCCAGGAAGUCAGCCU 34.00 261(17.45%) 293 T 15564478 1095 HIV-1 (NL4-3) AF324493 Tat 5889 CUGCUUGUACCAAAUGCUAUU 85.00 21(1.40%) Hela 16290277 1566 HIV-1 (NL4-3) AF324493 tat 5888 CUGCUUGUACCAAUUGCUAUU 95.00 86(5.75%) H9 15006606 1016 HIV-1 (NL4-3) AF324493 Tat 5968 UAUGGCAGGAAGAAGCGGA 61.00 1287(86.03%) jurkat 12438622 1017 HIV-1 (NL4-3) AF324493 Tat 5851 CUAGAGCCCUGGAAGCAUC 64.00 292(19.52%) jurkat 12438622 1018 HIV-1 (NL4-3) AF324493 Tat 5979 GAAGCGGAGACAGCGACGA 51.00 724(48.40%) jurkat 12438622 1022 HIV-1 (NL4-3) AF324493 Tat 5968 UAUGGCAGGAAGAAGCGGA 94.00 1287(86.03%) Magi 12438622 1023 HIV-1 (NL4-3) AF324493 Tat 5851 CUAGAGCCCUGGAAGCAUC 90.00 292(19.52%) Magi 12438622 1024 HIV-1 (NL4-3) AF324493 Tat 5979 GAAGCGGAGACAGCGACGA 95.00 724(48.40%) Magi 12438622 1030 HIV-1 (NL4-3) AF324493 Tat 5888 CUGCUUGUACCAAUUGCUA 93.00 86(5.75%) 293 T 12930953 1031 HIV-1 (NL4-3) AF324493 Tat 5888 CUGCUUGUACCAAUUGCUA 97.00 86(5.75%) 293 T 14557638 1042 HIV-1 (NL4-3) AF324493 Tat 5993 GACGAAGAGCUCAUCAGAACA 85.00 2(0.13%) 293 T 14966264 1107 HIV-1 (NL4-3) AF324493 Tat 5888 CUGCUUGUACCAAUUGCUA 65.00 86(5.75%) 293 T 16840344 1213 HIV-1 (NL4-3) AF324493 Tat 5997 AAGAGCUCAUCAGAACAGUCA 92.00 1(0.07%) Hela 17360756 1481 HIV-1 (NL4-3) AF324493 Tat 132 CAUCUCCUAUGGCAGGAAGAA 73.80 809(54.08%) HEK 293a 19497094 1482 HIV-1 (NL4-3) AF324493 Tat 140 AUGGCAGGAAGAAGCGGAGAC 94.30 1047(69.99%) HEK 293a 19497094 1483 HIV-1 (NL4-3) AF324493 Tat 143 GCAGGAAGAAGCGGAGACAGC 97.70 802(53.61%) HEK 293a 19497094 1484 HIV-1 (NL4-3) AF324493 Tat 147 GAAGAAGCGGAGACAGCGAC 94.20 784(52.41%) HEK 293a 19497094 1607 HIV-1 (NL4-3) AF324493 tat K*5983 GCGGAGACAGCGACGAAGAGC 92.00 148(9.89%) 293 T 18596982 1589 pNL-ADA M19921 tat 5916 GUGUUGCUUUCAUUGCCAAGUUUGU 0.00 102(6.82%) 293 T 14581533

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