A database of FDA approved therapeutic peptides and proteins
ID | ThPPID | Name | Peptide Sequence | Length | Functional Classification | Disease | Brand | Company | Physical Appearance | Route of Administartion | Category | Target |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1032 | Th1006 | Bivalirudin | FPRPGGGGNGDFEEIPEEYL Full view | 20 | Ia | Hematological,Metabolic | Angiomax | Medicines Co or MDCO | White lyophilized cake in single-use vials | Intravenous infusion | Antithrombins | Prothrombin |
1257 | Th1036 | Aldesleukin | MAPTSSSTKKTQLQLEHLLL Full view | 134 | Ib | Cancer/Infectious | Proleukin | Chiron Corp | Sterile, white to off-white, lyophilized cake | Intravenous administration | Antineoplastic Agents, Anti-HIV agents | Interleukin-2 receptor subunit beta,Interleukin-2 receptor subunit alpha,Cytokine receptor common subunit gamma |
1290 | Th1042 | Collagenase | MKRKCLSKRLMLAITMATIF Full view | 255 | Ic | Hematological | Xiaflex | Auxilium | Sterile lyophilized powder (white cake) | Intralesional Injection | N.A. | Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain |
1409 | Th1067 | Daptomycin | N.A. Full view | 0 | IIa | Infectious | CUBICIN | Cubist Pharmaceuticals, Inc | Sterile, preservative-free, pale yellow to light brown, lyophilized cake containing approx 500 mg of daptomycin | Intravenous(IV) Injection | N.A. | B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c |
1453 | Th1083 | Coagulation Factor Ix | YNSGKLEEFVQGNLERECME Full view | 415 | Ia | Hematological/Metabolic/genetic | Alprolix | Biogen Idec Inc., and Genentech USA, Inc | Sterile, non-pyrogenic, preservative-free, white to off-white, lyophilized powder to cake for reconstitution with the provided diluent | Intravenous infusion | Coagulants and Thrombotic Agents | N.A. |
1455 | Th1085 | Agalsidase Beta | LDNGLARTPTMGWLHWERFM Full view | 398 | Ia | Metabolic | Fabrazyme | Genzyme Corp | Sterile, nonpyrogenic, white to off-white, lyophilized cake or powder for reconstitution with Sterile Water for Injection | N.A. | Enzyme Replacement Agents | N.A. |
1477 | Th1097 | Alglucosidase Alfa | AHPGRPRAVPTQCDVPPNSR Full view | 882 | Ic | Metabolic | LUMIZYME | Genzyme | Sterile, nonpyrogenic, white to off-white, lyophilized cake or powder for reconstitution with 10.3 Ml Sterile Water for Injection, USP | Intravenous infusion | Enzyme Replacement Agents | Cation-dependent mannose-6-phosphate receptor,Glycogen |
1604 | Th1130 | Brentuximab Vedotin | Heavy chain:QIQLQQSG Full view | 664 | IIb | Cancer | Adcetris | Seattle Genetics | Sterile, white to off-white, preservative-free lyophilized cake or powder in single-use vials. | Intravenous infusion | N.A. | Tumor necrosis factor receptor superfamily member 8 |