Total number of Results for 293 FT are 8
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna1795 GACCCUCAAAAACAAGUUU
CUGGGAGUUUUUGUUCAAA
15 55 -40 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1796 AGAUCAAGACCCUCAAAAA
UCUAGUUCUGGGAGUUUUU
50 85 -35 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1797 CAGAUCAAGACCCUCAAAA
GUCUAGUUCUGGGAGUUUU
44 70 -26 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1798 ACAGAUCAAGACCCUCAAA
UGUCUAGUUCUGGGAGUUU
40 60 -20 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1799 AAAAACAAGUUUGCCUCCUU
UUUUUGUUCAAACGGAGGAA
10 23 -13 KRT6a Pachyonychia congenita (PC) c.513C>A,p.Asn171Lys rs59685571
17145926
aspsirna1800 UCAAGACCCUC---AACAAGUU
AGUUCUGGGAG---UUGUUCAA
75 20 55 KRT6a Pachyonychia congenita (PC) c.514_516delAAC,p.Asn172del rs26760745
17145926
aspsirna1801 CAAGACCCUC---AACAAGUUU
GUUCUGGGAG---UUGUUCAAA
30 20 10 KRT6a Pachyonychia congenita (PC) c.514_516delAAC,p.Asn172del rs26760745
17145926
aspsirna1802 AAGACCCUC---AACAAGUUUG
UUCUGGGAG---UUGUUCAAAC
25 5 20 KRT6a Pachyonychia congenita (PC) c.514_516delAAC,p.Asn172del rs26760745
17145926