Total number of Results for HaCaT are 77
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)		 Efficacy
for wild (%)		 Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna0485 CUCAACAAUAAGUUUGCCC
GAGUUGUUAUUCAAACGGG		 0 0 0 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0486 UCAACAAUAAGUUUGCCCC
AGUUGUUAUUCAAACGGGG		 0 0 0 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0487 CAACAAUAAGUUUGCCCCC
GUUGUUAUUCAAACGGGGG		 0 0 0 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0488 AACAAUAAGUUUGCCCCCU
UUGUUAUUCAAACGGGGGA		 0 0 0 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0489 ACAAUAAGUUUGCCCCCUU
UGUUAUUCAAACGGGGGAA		 62 15 47 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0490 CAAUAAGUUUGCCCCCUUC
GUUAUUCAAACGGGGGAAG		 70 42 28 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0491 AAUAAGUUUGCCCCCUUCA
UUAUUCAAACGGGGGAAGU		 40 0 40 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0492 AUAAGUUUGCCCCCUUCAU
UAUUCAAACGGGGGAAGUA		 90 18 72 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0493 UAAGUUUGCCCCCUUCAUC
AUUCAAACGGGGGAAGUAG		 20 0 20 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0494 AAGUUUGCCCCCUUCAUCG
UUCAAACGGGGGAAGUAGC		 30 0 30 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0495 AGUUUGCCCCCUUCAUCGA
UCAAACGGGGGAAGUAGCU		 79 30 49 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0496 GUUUGCCCCCUUCAUCGAC
CAAACGGGGGAAGUAGCUG		 90 35 55 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0497 UUUGCCCCCUUCAUCGACA
AAACGGGGGAAGUAGCUGU		 30 0 30 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0498 UUGCCCCCUUCAUCGACAA
AACGGGGGAAGUAGCUGUU		 40 10 30 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0499 UGCCCCCUUCAUCGACAAG
ACGGGGGAAGUAGCUGUUC		 12 0 12 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0500 GCCCCCUUCAUCGACAAGG
CGGGGGAAGUAGCUGUUCC		 35 12 23 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0501 CCCCCUUCAUCGACAAGGU
GGGGGAAGUAGCUGUUCCA		 60 35 25 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0502 CCCCUUCAUCGACAAGGUG
GGGGAAGUAGCUGUUCCAC		 62 35 27 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0503 CCCUUCAUCGACAAGGUGC
GGGAAGUAGCUGUUCCACG		 41 22 19 KRT5 Epidermolysis bullosa simplex (EBS) c.541T>C ,p.Ser181Pro rs60715293
21716320
aspsirna0504 GUUCCUGGAGCAGCAGAAG
CAAGGACCUCGUCGUCUUC		 45 0 45 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0505 UUCCUGGAGCAGCAGAAGA
AAGGACCUCGUCGUCUUCU		 40 0 40 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0506 UCCUGGAGCAGCAGAAGAA
AGGACCUCGUCGUCUUCUU		 40 0 40 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0507 CCUGGAGCAGCAGAAGAAG
GGACCUCGUCGUCUUCUUC		 34 0 34 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0508 CUGGAGCAGCAGAAGAAGG
GACCUCGUCGUCUUCUUCC		 42 0 42 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0509 UGGAGCAGCAGAAGAAGGU
ACCUCGUCGUCUUCUUCCA		 50 0 50 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0510 GGAGCAGCAGAAGAAGGUU
CCUCGUCGUCUUCUUCCAA		 70 0 70 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0511 GAGCAGCAGAAGAAGGUUC
CUCGUCGUCUUCUUCCAAG		 73 0 73 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0512 AGCAGCAGAAGAAGGUUCU
UCGUCGUCUUCUUCCAAGA		 10 0 10 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0513 GCAGCAGAAGAAGGUUCUG
CGUCGUCUUCUUCCAAGAC		 10 0 10 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0514 CAGCAGAAGAAGGUUCUGG
GUCGUCUUCUUCCAAGACC		 0 0 0 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0515 AGCAGAAGAAGGUUCUGGA
UCGUCUUCUUCCAAGACCU		 42 0 42 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0516 GCAGAAGAAGGUUCUGGAC
CGUCUUCUUCCAAGACCUG		 30 0 30 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0517 CAGAAGAAGGUUCUGGACA
GUCUUCUUCCAAGACCUGU		 25 0 25 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0518 AGAAGAAGGUUCUGGACAC
UCUUCUUCCAAGACCUGUG		 0 0 0 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0519 GAAGAAGGUUCUGGACACC
CUUCUUCCAAGACCUGUGG		 8 10 -2 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0520 AAGAAGGUUCUGGACACCA
UUCUUCCAAGACCUGUGGU		 25 0 25 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0521 AGAAGGUUCUGGACACCAA
UCUUCCAAGACCUGUGGUU		 45 0 45 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna0522 GAAGGUUCUGGACACCAAG
CUUCCAAGACCUGUGGUUC		 19 10 9 KRT5 Epidermolysis bullosa simplex (EBS) c.579C>G, p.Asn193Lys rs60586163
21716320
aspsirna1803 GCGCUUCAGGCACUACAAAUA
CGCGAAGUCCGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1804 CCGCUUCAGGCACUACAAAUA
GGCGAAGUCCGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1805 GGGCUUCAGGCACUACAAAUA
CCCGAAGUCCGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1806 GCCCUUCAGGCACUACAAAUA
CGGGAAGUCCGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1807 GCGGUUCAGGCACUACAAAUA
CGCCAAGUCCGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1808 GCGCUUGAGGCACUACAAAUA
CGCGAACUCCGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1809 GCGCUUCAGCCACUACAAAUA
CGCGAAGUCGGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1810 GCGCUUCAGGGACUACAAAUA
CGCGAAGUCCCUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1811 GCGCUUCAGGCAGUACAAAUA
CGCGAAGUCCGUCAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1812 GCGCUUCAGGCACUAGAAAUA
CGCGAAGUCCGUGAUCUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1813 GCGCUUGAGCCACUACAAAUA
CGCGAACUCGGUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1814 GCGCUUCAGCGACUACAAAUA
CGCGAAGUCGCUGAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1815 GCGCUUCAGCCAGUACAAAUA
CGCGAAGUCGGUCAUGUUUAU		 NA NA NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna1816 GCGCUUCAGCCACUAGAAAUA
CGCGAAGUCGGUGAUCUUUAU		 NA Poor efficacy NA F3 /CD142 Malignant melanoma c.489G>A,p.Arg163= rs26759878
12527766
aspsirna3116 GCACAAGUGACUAGUCCUA
CGUGUUCACUGAUCAGGAU		 65 30 35 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3117 CUAGUCCUAUGAUGUACAA
GAUCAGGAUACUACAUGUU		 75 30 45 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3118 UCUUCUCUCUCUCUCUAUA
AGAAGAGAGAGAGAGAUAU		 78 30 48 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3119 UCUGAGGCUGAGCAUUAUA
AGACUCCGACUCGUAAUAU		 79 30 49 KRT6A Pachyonychia congenita (PC) NA NA
17762855
aspsirna3256 GGCCUCUUGGCUCUUGGAU
CCGGAGAACCGAGAACCUA		 80 0 80 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3257 GGCCUCUUGGCUCUUGGAU
CCGGAGAACCGAGAACCUA		 80 2 78 KRT9 Epidermolytic palmoplantar keratoderma (EPPK) c.500delAinsGGCT,p.Tyr167delinsTrpLeu rs59317143
27003758
aspsirna3509 UGCAAAAUCUUAAUGAUAC
ACGUUUUAGAAUUACUAUG		 45 30 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3510 GCAAAAUCUUAAUGAUACA
CGUUUUAGAAUUACUAUGU		 35 20 15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3511 CAAAAUCUUAAUGAUACAU
GUUUUAGAAUUACUAUGUA		 82 33 49 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3512 AAAAUCUUAAUGAUACAUU
UUUUAGAAUUACUAUGUAA		 10 20 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3513 AAAUCUUAAUGAUACAUUA
UUUAGAAUUACUAUGUAAU		 40 40 0 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3514 AAUCUUAAUGAUACAUUAG
UUAGAAUUACUAUGUAAUC		 79 50 29 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3515 AUCUUAAUGAUACAUUAGC
UAGAAUUACUAUGUAAUCG		 83 50 33 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3516 UCUUAAUGAUACAUUAGCU
AGAAUUACUAUGUAAUCGA		 90 45 45 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3517 CUUAAUGAUACAUUAGCUU
GAAUUACUAUGUAAUCGAA		 41 20 21 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3518 UUAAUGAUACAUUAGCUUC
AAUUACUAUGUAAUCGAAG		 60 20 40 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3519 UAAUGAUACAUUAGCUUCC
AUUACUAUGUAAUCGAAGG		 90 0 90 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3520 AAUGAUACAUUAGCUUCCU
UUACUAUGUAAUCGAAGGA		 88 10 78 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3521 AUGAUACAUUAGCUUCCUA
UACUAUGUAAUCGAAGGAU		 92 0 92 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3522 UGAUACAUUAGCUUCCUAC
ACUAUGUAAUCGAAGGAUG		 90 56 34 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3523 GAUACAUUAGCUUCCUACC
CUAUGUAAUCGAAGGAUGG		 30 20 10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3524 AUACAUUAGCUUCCUACCU
UAUGUAAUCGAAGGAUGGA		 10 25 -15 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3525 UACAUUAGCUUCCUACCUG
AUGUAAUCGAAGGAUGGAC		 20 30 -10 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3526 ACAUUAGCUUCCUACCUGG
UGUAAUCGAAGGAUGGACC		 60 30 30 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254
aspsirna3527 CAUUAGCUUCCUACCUGGA
GUAAUCGAAGGAUGGACCU		 36 30 6 KRT12 Meesmann epithelial corneal dystrophy (MECD) c.404G>C,p.Arg135Thr rs57218384
23233254