Total number of Results for S2 are 32
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna2995 CAUAGUCAUUUCUAAAAGU
GUAUCAGUAAAGAUUUUCA
95 20 75 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna2996 CACUAGUAGAAAGUAUAAU
GUGAUCAUCUUUCAUAUUA
90 20 70 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna2997 GUAGAAAGUAUAAUUUCAA
CAUCUUUCAUAUUAAAGUU
93 20 73 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna2998 AGUCAUUUCUAAAAGUCAC
UCAGUAAAGAUUUUCAGUG
80 20 60 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna2999 UUCUAAAAGUCACUAGUAG
AAGAUUUUCAGUGAUCAUC
85 20 65 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3000 AAAAGUCACUAGUAGAAAG
UUUUCAGUGAUCAUCUUUC
88 20 68 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3001 CAUAGUCAUAUCUAAAAGU
GUAUCAGUAUAGAUUUUCA
70 20 50 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3002 CAUAGUCAUGUCUAAAAGU
GUAUCAGUACAGAUUUUCA
80 20 60 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3003 CACUAGUAGUAAGUAUAAU
GUGAUCAUCAUUCAUAUUA
55 20 35 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3004 CACUAGUAGGAAGUAUAAU
GUGAUCAUCCUUCAUAUUA
80 20 60 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3005 CACUAGUAGCAAGUAUAAU
GUGAUCAUCGUUCAUAUUA
70 20 50 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3006 UUCUAAAAGACACUAGUAG
AAGAUUUUCUGUGAUCAUC
80 20 60 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3007 UUCUAAAAGGCACUAGUAG
AAGAUUUUCCGUGAUCAUC
90 20 70 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3008 GGAUUUAUGUGGAUACAAA
CCUAAAUACACCUAUGUUU
90 15 75 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3009 GAUUUAUGUGGAUACAAAU
CUAAAUACACCUAUGUUUA
95 15 80 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3010 GAUACAAAUUCUCCUUUAAA
CUAUGUUUAAGAGGAAAUUU
90 15 75 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3011 UGUGGAUACAAAUUCUCCU
ACACCUAUGUUUAAGAGGA
98 15 83 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3012 UCCUUUAAAGUGUUUCUUC
AGGAAAUUUCACAAAGAAG
95 15 80 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3013 UUCCCUUAAUAUUUAUCUG
AAGGGAAUUAUAAAUAGAC
90 15 75 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3014 UUUAUGUGGAUACAAAUUC
AAAUACACCUAUGUUUAAG
98 15 83 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3015 UUAUGUGGAUACAAAUUCU
AAUACACCUAUGUUUAAGA
95 15 80 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3016 UAUGUGGAUACAAAUUCUC
AUACACCUAUGUUUAAGAG
90 15 75 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3017 AUGUGGAUACAAAUUCUCC
UACACCUAUGUUUAAGAGG
90 15 75 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3018 UGUGGAUACAAAUUCUCCU
ACACCUAUGUUUAAGAGGA
88 15 73 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3019 GGAUUUAUGAGGAUACAAA
CCUAAAUACUCCUAUGUUU
90 15 75 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3020 AAGGAUUUAUGGGGAUACAAA
UUCCUAAAUACCCCUAUGUUU
96 15 81 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3021 CAUAGUCAUAUCAAAAAGU
GUAUCAGUAUAGUUUUUCA
10 8 2 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3022 CAUAGUCAUAUCUUAAAGU
GUAUCAGUAUAGAAUUUCA
15 8 7 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3023 CAUAGUCAUAUCUAUAAGU
GUAUCAGUAUAGAUAUUCA
10 8 2 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3024 CACUAGUAGUAACUAUAAU
GUGAUCAUCAUUGAUAUUA
15 8 7 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3025 CACUAGUAGUAAGAAUAAU
GUGAUCAUCAUUCUUAUUA
15 8 7 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551
aspsirna3026 CACUAGUAGUAAGUUUAAU
GUGAUCAUCAUUCAAAUUA
20 8 12 SNCA Parkinsons disease (PD) SNCA locus triplication NA
25965551