ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna2995 | CAUAGUCAUUUCUAAAAGU GUAUCAGUAAAGAUUUUCA |
95 | 20 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna2996 | CACUAGUAGAAAGUAUAAU GUGAUCAUCUUUCAUAUUA |
90 | 20 | 70 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna2997 | GUAGAAAGUAUAAUUUCAA CAUCUUUCAUAUUAAAGUU |
93 | 20 | 73 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna2998 | AGUCAUUUCUAAAAGUCAC UCAGUAAAGAUUUUCAGUG |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna2999 | UUCUAAAAGUCACUAGUAG AAGAUUUUCAGUGAUCAUC |
85 | 20 | 65 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3000 | AAAAGUCACUAGUAGAAAG UUUUCAGUGAUCAUCUUUC |
88 | 20 | 68 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3001 | CAUAGUCAUAUCUAAAAGU GUAUCAGUAUAGAUUUUCA |
70 | 20 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3002 | CAUAGUCAUGUCUAAAAGU GUAUCAGUACAGAUUUUCA |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3003 | CACUAGUAGUAAGUAUAAU GUGAUCAUCAUUCAUAUUA |
55 | 20 | 35 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3004 | CACUAGUAGGAAGUAUAAU GUGAUCAUCCUUCAUAUUA |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3005 | CACUAGUAGCAAGUAUAAU GUGAUCAUCGUUCAUAUUA |
70 | 20 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3006 | UUCUAAAAGACACUAGUAG AAGAUUUUCUGUGAUCAUC |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3007 | UUCUAAAAGGCACUAGUAG AAGAUUUUCCGUGAUCAUC |
90 | 20 | 70 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3008 | GGAUUUAUGUGGAUACAAA CCUAAAUACACCUAUGUUU |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3009 | GAUUUAUGUGGAUACAAAU CUAAAUACACCUAUGUUUA |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3010 | GAUACAAAUUCUCCUUUAAA CUAUGUUUAAGAGGAAAUUU |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3011 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
98 | 15 | 83 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3012 | UCCUUUAAAGUGUUUCUUC AGGAAAUUUCACAAAGAAG |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3013 | UUCCCUUAAUAUUUAUCUG AAGGGAAUUAUAAAUAGAC |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3014 | UUUAUGUGGAUACAAAUUC AAAUACACCUAUGUUUAAG |
98 | 15 | 83 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3015 | UUAUGUGGAUACAAAUUCU AAUACACCUAUGUUUAAGA |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3016 | UAUGUGGAUACAAAUUCUC AUACACCUAUGUUUAAGAG |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3017 | AUGUGGAUACAAAUUCUCC UACACCUAUGUUUAAGAGG |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3018 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
88 | 15 | 73 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3019 | GGAUUUAUGAGGAUACAAA CCUAAAUACUCCUAUGUUU |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3020 | AAGGAUUUAUGGGGAUACAAA UUCCUAAAUACCCCUAUGUUU |
96 | 15 | 81 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3021 | CAUAGUCAUAUCAAAAAGU GUAUCAGUAUAGUUUUUCA |
10 | 8 | 2 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3022 | CAUAGUCAUAUCUUAAAGU GUAUCAGUAUAGAAUUUCA |
15 | 8 | 7 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3023 | CAUAGUCAUAUCUAUAAGU GUAUCAGUAUAGAUAUUCA |
10 | 8 | 2 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3024 | CACUAGUAGUAACUAUAAU GUGAUCAUCAUUGAUAUUA |
15 | 8 | 7 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3025 | CACUAGUAGUAAGAAUAAU GUGAUCAUCAUUCUUAUUA |
15 | 8 | 7 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | ||
aspsirna3026 | CACUAGUAGUAAGUUUAAU GUGAUCAUCAUUCAAAUUA |
20 | 8 | 12 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |