ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0530 | AUGGUGUGACAACAGUGGCUG UACCACACUGUUGUCACCGAC |
39 | 20 | 19 | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0532 | AAUGUUGGAGGAGCAGUGGUG UUACAACCUCCUCGUCACCAC |
NA | NA | NA | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0533 | AAGGACCAGUUGGGCAAGAAU UUCCUGGUCAACCCGUUCUUA |
NA | NA | NA | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0534 | AUGGUGUGACAACAGUGGCUG UACCACACUGUUGUCACCGAC |
39 | 25 | 14 | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0535 | CAUGGUGUGACAACAGUGGCU GUACCACACUGUUGUCACCGA |
45 | 70 | -25 | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0536 | GCAUGGUGUGACAACAGUGGC CGUACCACACUGUUGUCACCG |
10 | 50 | -40 | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0537 | AUGGUGUGAGAACAGUGGCUG UACCACACUCUUGUCACCGAC |
75 | 55 | 20 | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0538 | AUGGUGUGACAUCAGUGGCUG UACCACACUGUAGUCACCGAC |
51 | 2 | 49 | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |
|
aspsirna0539 | AUGGUGUGACAACAGUGGCUG UACCACACUGUUGUCACCGAC |
55 | 40 | 15 | SNCA | Parkinsons disease (PD) | c.157G>A,p.Ala53Thr | rs10489387 | ![]() |