ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1789 | GCCAUGCAUGUGUUCAGAA CGGUACGUACACAAGUCUU |
NA | 20 | NA | TTR | Amyloidogenic transthyretin amyloidosis | c.148G>A,p.Val50Met | rs28933979 | ||
aspsirna1790 | GUGGCCAUGCAUGUGUUCA CACCGGUACGUACACAAGU |
NA | 5 | NA | TTR | Amyloidogenic transthyretin amyloidosis | c.148G>A,p.Val50Met | rs28933979 | ||
aspsirna1791 | UGUGGCCAUGCAUGUGUUC ACACCGGUACGUACACAAG |
NA | 5 | NA | TTR | Amyloidogenic transthyretin amyloidosis | c.148G>A,p.Val50Met | rs28933979 | ||
aspsirna1792 | AAUGUGGCCAUGCAUGUGU UUACACCGGUACGUACACA |
NA | 35 | NA | TTR | Amyloidogenic transthyretin amyloidosis | c.148G>A,p.Val50Met | rs28933979 | ||
aspsirna1793 | CAAUGUGGCCAUGCAUGUG GUUACACCGGUACGUACAC |
NA | 65 | NA | TTR | Amyloidogenic transthyretin amyloidosis | c.148G>A,p.Val50Met | rs28933979 |