ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1746 | UGACUCCUGAGGAGAAGUU ACUGAGGACUCCUCUUCAG |
NA | 65 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ||
aspsirna1747 | UGACUCCUGAGGAGAAGUG ACUGAGGACUCCUCUUCAG |
NA | 12 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ||
aspsirna1748 | UGACUCCUGAGGAGAAGUG ACUGAGGACUCCUCUUCAC |
NA | 25 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ||
aspsirna1749 | UGACUCCUGAGGAGAAGUC ACUGAGGACUCCUCUUCAG |
NA | 10 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ||
aspsirna1750 | UGACUCCUGUGGAGAAGUC ACUGAGGACACCUCUUCAG |
NA | 10 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ||
aspsirna1751 | UGACUCCUGUGGAGAAGUU ACUGAGGACACCUCUUCAG |
NA | 5 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ||
aspsirna1752 | UGACUCCUGUGGAGAAGUG ACUGAGGACACCUCUUCAG |
NA | 10 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ||
aspsirna1753 | UGACUCCUGUGGAGAAGUG ACUGAGGACACCUCUUCAC |
NA | NA | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 |