Total number of Results for TTR are 6
ASPsiRNA ID Pairing of target region (top) and ASP-siRNA (bottom) Efficacy (mut)(%) Efficacy (wt) (%) Diff Gene Disease Mutation RefSNP Analysis Pubmed ID
ASPsiRNA ID Mutant allele/ASP-siRNA Efficacy
for mutant(%)
Efficacy
for wild (%)
Relative Difference (%) Gene Disease Mutation RefSNP Analysis Pubmed ID
aspsirna1789 GCCAUGCAUGUGUUCAGAA
CGGUACGUACACAAGUCUU
NA 20 NA TTR Amyloidogenic transthyretin amyloidosis c.148G>A,p.Val50Met rs28933979
16225852
aspsirna1790 GUGGCCAUGCAUGUGUUCA
CACCGGUACGUACACAAGU
NA 5 NA TTR Amyloidogenic transthyretin amyloidosis c.148G>A,p.Val50Met rs28933979
16225852
aspsirna1791 UGUGGCCAUGCAUGUGUUC
ACACCGGUACGUACACAAG
NA 5 NA TTR Amyloidogenic transthyretin amyloidosis c.148G>A,p.Val50Met rs28933979
16225852
aspsirna1792 AAUGUGGCCAUGCAUGUGU
UUACACCGGUACGUACACA
NA 35 NA TTR Amyloidogenic transthyretin amyloidosis c.148G>A,p.Val50Met rs28933979
16225852
aspsirna1793 CAAUGUGGCCAUGCAUGUG
GUUACACCGGUACGUACAC
NA 65 NA TTR Amyloidogenic transthyretin amyloidosis c.148G>A,p.Val50Met rs28933979
16225852
aspsirna1794 UCAAUGUGGCCAUGCAUGU
AGUUACACCGGUACGUACA
NA 15 NA TTR Familial amyloidotic polyneuropathy (FAP) c.148G>A,p.Val50Met rs28933979
16225852