ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
aspsirna2095 | UUGUGGUAGUUGGAGCUGU AACACCAUCAACCUCGACA |
20 | 0 | 20 | KRAS | Cancer | c.35G>T,p.Gly12Val | rs12191352 | ![]() |
|
aspsirna2116 | UUGUGGUAGUUGGAGCUGU AACACCAUCAACCUCGACA |
20 | 0 | 20 | KRAS | Cancer | c.35G>T,p.Gly12Val | rs12191352 | ![]() |
|
aspsirna1951 | GGCCAAAGGGUGAGCGUGU CCGGUUUCCCACUCGCACA |
NA | NA | 51 | COL6A3 | Dominant ullrich muscular dystrophy | (IVS16DS plus 1G-A) in intron 16 | NA | ![]() |
|
aspsirna1962 | GGCCAAAGGGUGAGCGUGU CCGGUUUCCCACUCGCACA |
NA | NA | 56 | COL6A3 | Dominant ullrich muscular dystrophy | (IVS16DS plus 1G-A) in intron 16 | NA | ![]() |
|
aspsirna1973 | GCCAAAGGGUGAGCGUGGG CGGUUUCCCACUCGCACCA |
59 | 30 | 29 | COL6A3 | Congenital muscular dystrophy type Ullrich (UCMD) | (IVS16DS plus 1G-A) in intron 16 | NA | ![]() |
|
aspsirna0366 | GACCUCCAGGUAUCAAAGU CUGGAGGUCCAUAGUUUCA |
86 | 62 | 24 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 | ![]() |
|
aspsirna1747 | UGACUCCUGAGGAGAAGUG ACUGAGGACUCCUCUUCAG |
NA | 12 | NA | HBB | Sickle cell anemia | c.365A>T (p.Glu122Val) | rs33987957 | ![]() |