| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2102 | AGUUGGAGCUGUUGGCGUA UCAACCUCGACAACCGCAU |
75 | 70 | 5 | KRAS | Cancer | c.35G>T,p.Gly12Val | rs12191352 | 
|
|
| aspsirna2123 | AGUUGGAGCUGUUGGCGUA UCAACCUCGACAACCGCAU |
75 | 70 | 5 | KRAS | Cancer | c.35G>T,p.Gly12Val | rs12191352 |
|
|
| aspsirna2427 | AACUCCUCCGCUCAACUUU UUGAGGAGGCGAGUUGAAA |
47 | 70 | -23 | KRAS | NA | NA | NA |
|
|
| aspsirna2234 | UUCAGCAGCAGCAUCAGCAGU AAGUCGUCGUCGUAGUCGUCU |
70 | 35 | 35 | ATN-1 | Dentatorubral-pallidoluysian atrophy (DRPLA) | c.1462_1464CAG(90_93) | rs19392293 |
|
|
| aspsirna1890 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
57 | 2 | 55 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1892 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
65 | 15 | 50 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna1894 | CUGGUGAAGCUUGUCGUCC GACCACUUCGAACAGCAGG |
60 | 15 | 45 | COL1A1 | Osteogenesis Imperfecta (OI) | c.3244G>T,p.Gly1082Cys | rs72656303 |
|
|
| aspsirna0359 | AGGUAUCAAAGUUCCAGCU UCCAUAGUUUCAAGGUCGA |
80 | 5 | 75 | COL3A1 | Vascular Ehlers-Danlos Syndrome (vEDs) | c.764G>T,p.Gly255Val | rs58777960 |
|
|
| aspsirna3031 | CAGCAGCAGCAUCAGCAGC GUCGUCGUCGUAGUCGUCG |
70 | 30 | 40 | ATXN3 | Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs19392292 |
|
|
| aspsirna0779 | CAGCAGCAGCAUCAGCAGC GUCGUCGUCGUAGUCGUCG |
66 | 20 | 46 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0074 | CGACAGUGAUCUUCAUCAC GCUGUCACUAGAAGUAGUG |
14 | 60 | -46 | APP | Alzheimers disease | c.2010_2011delGAinsTC (p.Lys670_Met671delinsAsnLeu) | rs28186516 |
|
|
| aspsirna3759 | AAAGUUGCGCGGAGGAGUU UUUCAACGCGCAUCCUCAA |
90 | 25 | 65 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
