| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna0437 | UACAGUGUUGUGGUUGGUA AUGUCACAACACCAACCAU |
65 | 7 | 58 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | 
|
|
| aspsirna0475 | GCAGCAGAAGAAGGUUCUG CGUCGUCUUCUUCCAAGAC |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 |
|
|
| aspsirna0513 | GCAGCAGAAGAAGGUUCUG CGUCGUCUUCUUCCAAGAC |
10 | 0 | 10 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.579C>G, p.Asn193Lys | rs60586163 |
|
|
| aspsirna0766 | ACUUGAGCAGUGUGACUGC UGAACUCGUCACACUGACG |
48 | 32 | 16 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0767 | CUUGAGCAAAGUGACUGCU GAACUCGUUCCACUGACGA |
78 | 23 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0768 | UUGAGCAAUUUGACUGCUG AACUCGUUACACUGACGAC |
98 | 22 | 76 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna2335 | UCACAUUGCGCAAGUCUCC AGUGUAACGCGUUCAGAGG |
45 | 40 | 5 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2337 | AGUGUAACGGGUUCAGAGG UCACAUUGCCCAAGUCUCC |
88 | NA | NA | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna3768 | AAAGUUGCGCGGAGGAGUU UUUCAACGCCCCUCCUCAA |
90 | 38 | 52 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|