| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2257 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
88 | 10 | 78 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | 
|
|
| aspsirna2270 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2286 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 30 | 50 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2324 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
NA | NA | 40 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2334 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
75 | 45 | 30 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2336 | AGUGUAACGCGUUCAGAGG UCACAUUGCGCAAGUCUCC |
82 | NA | NA | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna2434 | AACUCCUCCCCGCAACUUU UUGAGGAGGGGCGUUGAAA |
29 | 70 | -41 | KRAS | NA | NA | NA |
|
|
| aspsirna3559 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
76 | 12 | 64 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna3562 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna3565 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
88 | 18 | 70 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna0957 | UUAAUGAUACAUUAGCUUC AAUUACUAUGUAAUCGAAG |
60 | 20 | 40 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.404G>C,p.Arg135Thr | rs57218384 |
|
|
| aspsirna3518 | UUAAUGAUACAUUAGCUUC AAUUACUAUGUAAUCGAAG |
60 | 20 | 40 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.404G>C,p.Arg135Thr | rs57218384 |
|
|
| aspsirna0213 | GCAGAAGCACCAGGAAAGA CGUCUUCGUGGUCCUUUCU |
3 | 2 | 1 | SNCA | Parkinsons disease (PD) | c.88G>C,p.Ala30Pro | rs10489387 |
|
|
| aspsirna0227 | GCAGAAGCACCAGGAAAGA CGUCUUCGUGGUCCUUUCU |
10 | 2 | 8 | SNCA | Parkinsons disease (PD) | c.88G>C,p.Ala30Pro | rs10489387 |
|
|
| aspsirna0714 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
90 | 32 | 58 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0734 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
90 | 32 | 58 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0763 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
49 | 22 | 27 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0764 | AGACUUGAGUAAUGUGACU CCUCUGAACGCGUUACACU |
55 | 32 | 23 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna0765 | GACUUGAGCAAUGUGACUG CCUCUGAACGCGUUACACU |
68 | 13 | 55 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna1001 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1007 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | Lowest effective | High discrimination | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
