| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2311 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
78 | 40 | 38 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | 
|
|
| aspsirna2084 | CUCCCCUGUAGCUAAGGCC GAGGGGACAUCGAUUCCGG |
58 | 45 | 13 | PPIB/Cyclophilin B | NA | NA | NA |
|
|
| aspsirna2452 | AACCCCUCCGCGCAACUUU UUGGGGAGGCGCGUUGAAA |
3 | 70 | -67 | KRAS | NA | NA | NA |
|
|
| aspsirna3265 | GCCUGCUCCCUCAUCCACUGU CGGACGAGGGAGUAGGUGACA |
44 | 22 | 22 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 |
|
|
| aspsirna0648 | CCACGCAGGAACUCAAUUC GGUGCGUCCUUGAGUUAAG |
30 | 78 | -48 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.470T>C,p.Met157Thr | rs59510579 |
|
|
| aspsirna0700 | AGACUUGGACCAGGCAGUC UCUGAACCUGGUCCGUCAG |
10 | 48 | -38 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0186 | AUCCUAAUGAUAGAUUAGC UAGGAUUACUAUCUAAUCG |
95 | 72 | 23 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 |
|
|
| aspsirna0052 | AUCCACUGUGUGCACUUCA UAGGUGACACACGUGAAGU |
60 | 82 | -22 | HTT | Huntington disease (HD) | c.6931T>C,c.52CAG(36_39) | rs362331 |
|
|
| aspsirna0550 | UGACGGAAAAGGAGUUGGA ACUGCCUUUUCCUCAACCU |
13 | NA | NA | COL1A2 | Osteogenesis Imperfecta (OI) | c.246T>C,NP_000080.2:p.Asp82= | rs1800222 |
|
|
| aspsirna0759 | UUGCGCAAUGUGACUGCUG AACGCGUUACACUGACGAC |
77 | 53 | 24 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
|
| aspsirna3715 | GGUUGGAGGAGAGAUGAUA CCAGCCUCCUCUCUACUAU |
90 | 88 | 2 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
