ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
aspsirna2028 | UUUCUGAGGAUCUCUCUGA AAAGACUCCUAGAGAGACU |
80 | 30 | 50 | P. luciferase | NA | NA | NA | ![]() |
|
aspsirna2172 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
88 | 15 | 73 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ![]() |
|
aspsirna3437 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
88 | 15 | 73 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ![]() |
|
aspsirna3447 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ![]() |
|
aspsirna3457 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ![]() |
|
aspsirna3467 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ![]() |
|
aspsirna3477 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
78 | 20 | 58 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ![]() |
|
aspsirna3487 | GUACUUCAACGCUAGAAGAU CAUGAAGUUGCGAUCUUCUA |
88 | 20 | 68 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 | ![]() |
|
aspsirna0462 | GCCCCCUUCAUCGACAAGG CGGGGGAAGUAGCUGUUCC |
35 | 12 | 23 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ![]() |
|
aspsirna0500 | GCCCCCUUCAUCGACAAGG CGGGGGAAGUAGCUGUUCC |
35 | 12 | 23 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 | ![]() |