| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2313 | GCGCAAUGUGACUGCUGAC CGCGUUACACUGACGACUG |
75 | 60 | 15 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | 
|
|
| aspsirna2033 | UCUAUGAGGAUCUCUCUGA AGAUACUCCUAGAGAGACU |
85 | 30 | 55 | P. luciferase | NA | NA | NA |
|
|
| aspsirna2090 | CCCUCCUGUAGCUAAGGCC GGGAGGACAUCGAUUCCGG |
64 | 45 | 19 | PPIB/Cyclophilin B | NA | NA | NA |
|
|
| aspsirna3263 | ACGCCUGCUCCCUCAUCCACU UGCGGACGAGGGAGUAGGUGA |
60 | 35 | 25 | HTT | Huntington disease (HD) | NM_002111.7:c.6931T>C | rs362331 |
|
|
| aspsirna0650 | ACGCAGGAACUCAAUUCUC UGCGUCCUUGAGUUAAGAG |
35 | 70 | -35 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.470T>C,p.Met157Thr | rs59510579 |
|
|
| aspsirna0188 | CCUAAUGAUAGAUUAGCUU GGAUUACUAUCUAAUCGAA |
80 | 50 | 30 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 |
|
|
| aspsirna0464 | CCCCUUCAUCGACAAGGUG GGGGAAGUAGCUGUUCCAC |
62 | 35 | 27 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0502 | CCCCUUCAUCGACAAGGUG GGGGAAGUAGCUGUUCCAC |
62 | 35 | 27 | KRT5 | Epidermolysis bullosa simplex (EBS) | c.541T>C ,p.Ser181Pro | rs60715293 |
|
|
| aspsirna0761 | GCGCAAUGUGACUGCUGAC CGCGUUACACUGACGACUG |
70 | 77 | -7 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C, p.Gly86Arg | rs12191243 |
|
