| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2170 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
85 | 5 | 80 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | 
|
|
| aspsirna3435 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
85 | 10 | 75 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3445 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
80 | 20 | 60 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3455 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 60 | 38 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3465 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 60 | 38 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3475 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
98 | 28 | 70 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna3485 | GGGACAGUAAUUCAACGCUU CCCUGUCAUUAAGUUGCGAA |
70 | 30 | 40 | HTT | Huntington disease (HD) | NM_002111.7:c.5165C>A | rs363125 |
|
|
| aspsirna0681 | CAGCAGCAGCAGAAGCAGCAGC GUCGUCGUCGUCUUCGUCGUCG |
57 | 40 | 17 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna3034 | CAGCAGCAGAAGCAGCAGC GUCGUCGUCUUCGUCGUCG |
87 | 25 | 62 | ATXN3 | Machado-Joseph Disease (MJD)/Spinocerebellar ataxia type 3 (SCA3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs19392292 |
|
|
| aspsirna0782 | CAGCAGCAGAAGCAGCAGC GUCGUCGUCUUCGUCGUCG |
30 | 35 | -5 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0838 | UGGGGACAGUAAUUCAACGCU ACCCCUGUCAUUAAGUUGCGA |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 |
|
|
| aspsirna0840 | CAGUAAUUCAACGCUAGAAGA GUCAUUAAGUUGCGAUCUUCU |
NA | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs363125 |
|
|
| aspsirna1795 | GACCCUCAAAAACAAGUUU CUGGGAGUUUUUGUUCAAA |
15 | 55 | -40 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna3769 | AAAGUUGCGCGGAGGAGUU UUUCAACGCUCCUCCUCAA |
90 | 58 | 32 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
