| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| aspsirna2046 | CUCUCCUGUAGCUAAGACC GAGAGGACAUCGAUUCUGG |
77 | 45 | 32 | PPIB/Cyclophilin B | NA | NA | NA | 
|
|
| aspsirna3183 | CCCGCACAGUUUCGACAUG GGGCGUGUCAAAGCUGUAC |
40 | 10 | 30 | TP63 | Ectrodactyly-Ectodermal Dysplasia-Clefting syndrome 3 (EEC3) | p.Arg132His,c.394G>A | rs19392114 |
|
|
| aspsirna3097 | UGACGGAGGUUGUGAGGCACU ACUGCCUCCAACACUCCGUGA |
80 | 15 | 65 | TP53 | Cancer | c.524G>A ,p.Arg175His | rs28934578 |
|
|
| aspsirna3102 | ACGGAGGUUGUGAGGCACU UGCCUCCAACACUCCGUGA |
88 | 28 | 60 | TP53 | Cancer | c.524G>A ,p.Arg175His | rs28934578 |
|
|
| aspsirna3104 | UGACGGAGGUUGUGAGGCACU ACUGCCUCCAACACUCCGUGA |
83 | 15 | 68 | TP53 | Cancer | c.524G>A ,p.Arg175His | rs28934578 |
|
|
| aspsirna3109 | ACGGAGGUUGUGAGGCACU UGCCUCCAACACUCCGUGA |
78 | 28 | 50 | TP53 | Cancer | c.524G>A ,p.Arg175His | rs28934578 |
|
|
| aspsirna1896 | AGGGCCUGUGUCACCCUCAGG UCCCGGACACAGUGGGAGUCC |
Moderate efficacy | Moderate efficacy | Poor discrimination | Myh6 | Human hypertrophic cardiomyopathy (HCM) | c.2384G>A,p.Arg795Gln | rs26760690 |
|
|
| aspsirna0597 | CAGGAACUCAAUUCUCAGC GUCCUUGAGUUAAGAGUCG |
90 | 0 | 90 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.488G>A,p.Arg163Gln | rs57758262 |
|
|
| aspsirna0332 | CCAGGCUCCCAGGCAGGGC GGUCCGAGGGUCCGUCCCG |
50 | 20 | 30 | COL7A1 | Dominant dystrophic epidermolysis bullosa(DDEB) | c.6127G>A,p.Gly2043Arg | rs12191283 |
|
|
| aspsirna0335 | AAAGCCUGGUAUUCCCAGG UUUCGGACCAUAAGGGUCC |
76 | 54 | 22 | COL7A1 | Dominant dystrophic epidermolysis bullosa(DDEB) | c.6127G>A,p.Gly2043Arg | rs12191283 |
|
|
| aspsirna0243 | GAAGAUUGCUGACUACAGC CUUCUAACGACUGAUGUCG |
60 | 24 | 36 | LRRK2 | Parkinsons disease (PD) | c.6055G>A,p.Gly2019Ser | rs34637584 |
|
|
| aspsirna0878 | AGAUCAAGACCCUCAAAAA UCUAGUUCUGGGAGUUUUU |
39 | 20 | 19 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |
|
|
| aspsirna3741 | AAAGUUGCGCGGAGGAGUU UUUCAACGCGCCUCCUUAA |
90 | 45 | 45 | PPIB/Cyclophilin B | PPIB-Related Osteogenesis Imperfecta (Type IX) | NA | NA |
|
