ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0556 | CAGAGUGGCU---GAGAUGAC GUCUCACCGA---CUCUACUG |
80 | 45 | 35 | TOR1A | DYT1 dystonia | c.907_909delGAG,p.Glu303del | rs72415998 | ||
aspsirna0557 | CU---GAGAUGACAUUUUUCCCC GA---CUCUACUGUAAAAAGGGG |
4 | 15 | -11 | TOR1A | DYT1 dystonia | c.907_909delGAG,p.Glu303del | rs72415998 | ||
aspsirna0558 | GAGUGGCU---GAGAUGACAUUUUUC CUCACCGA---CUCUACUGUAAAAAG |
0 | 27 | -27 | TOR1A | DYT1 dystonia | c.907_909delGAG,p.Glu303del | rs72415998 |