| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna1001 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | 20 | 60 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 | 
|
|
| aspsirna1000 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
95 | 10 | 85 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1002 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
96 | 23 | 73 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1003 | UGGAGACUUGGGCAAUGUG ACCUCUGAACCCGUUACAC |
82 | 5 | 77 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1004 | GGAGACUUGGGCAAUGUGA CCUCUGAACCCGUUACACU |
20 | 46 | -26 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1005 | GAGACUUGGGCAAUGUGAC CUCUGAACCCGUUACACUG |
NA | NA | NA | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1006 | UGGAGACUUGCGCAAUGUG ACCUCUGAACGCGUUACAC |
95 | Lowest effective | High discrimination | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1007 | GGAGACUUGCGCAAUGUGA CCUCUGAACGCGUUACACU |
80 | Lowest effective | High discrimination | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1008 | GAGACUUGCGCAAUGUGAC CUCUGAACGCGUUACACUG |
96 | Poor efficacy | High discrimination | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1009 | UGGAGACUUGGGCAAUGUG ACCUCUGAACCCGUUACAC |
82 | Poor efficacy | High discrimination | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1010 | GGAGACUUGGGCAAUGUGA CCUCUGAACCCGUUACACU |
20 | 46 | -26 | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|
|
| aspsirna1011 | GAGACUUGGGCAAUGUGAC CUCUGAACCCGUUACACUG |
NA | NA | NA | SOD1 | Amyotrophic Lateral Sclerosis (ALS) | c.256G>C,p.Gly86Arg | rs12191243 |
|