ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0967 | GCCGCGAGUCGGCCCGAGGC CGGCGCUCAGCCGGGCUCCG |
78 | 52 | 26 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0968 | GGCCUUCGAGUCCCUCAAGUCC CCGGAAGCUCAGGGAGUUCAGG |
80 | 55 | 25 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0969 | GCCGCGAGUCGGCCCGAGGC CGGCGCUCAGCCGGGCUCCG |
80 | 60 | 20 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0970 | GGCCUUCGAGUCCCUCAAGUCC CCGGAAGCUCAGGGAGUUCAGG |
80 | 48 | 32 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |