ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0923 | GAGUGGCUGAG---AUGACAUU CUCACCGACUC---UACUGUAA |
92 | 58 | 34 | TOR1A | Early onset torsion dystonia (DYT1) | c.907_909delGAG,p.Glu303del | rs72415998 | ![]() |
|
aspsirna0924 | GUGGCUGAG---AUGACAUUUU CACCGACUC---UACUGUAAAA |
85 | 19 | 66 | TOR1A | Early onset torsion dystonia (DYT1) | c.907_909delGAG,p.Glu303del | rs72415998 | ![]() |
|
aspsirna0925 | GUGGCUGAG---AUGACAUUUU CACCGACUC---UACUGUAAAA |
90 | 12 | 78 | TOR1A | Early onset torsion dystonia (DYT1) | c.907_909delGAG,p.Glu303del | rs72415998 | ![]() |
|
aspsirna0926 | GUGGCUGAG---AUGACAUUUU CACCGACUC---UACUGUAAAA |
NA | NA | NA | TOR1A | Early onset torsion dystonia (DYT1) | c.907_909delGAG,p.Glu303del | rs72415998 | ![]() |
|
aspsirna0927 | CAGAGUGGCUGAG---AUGACA GUCUCACCGACUC---UACUGU |
95 | 15 | 80 | TOR1A | Early onset torsion dystonia (DYT1) | c.907_909delGAG,p.Glu303del | rs72415998 | ![]() |