ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna1795 | GACCCUCAAAAACAAGUUU CUGGGAGUUUUUGUUCAAA |
15 | 55 | -40 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna1796 | AGAUCAAGACCCUCAAAAA UCUAGUUCUGGGAGUUUUU |
50 | 85 | -35 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna1797 | CAGAUCAAGACCCUCAAAA GUCUAGUUCUGGGAGUUUU |
44 | 70 | -26 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna1798 | ACAGAUCAAGACCCUCAAA UGUCUAGUUCUGGGAGUUU |
40 | 60 | -20 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna1799 | AAAAACAAGUUUGCCUCCUU UUUUUGUUCAAACGGAGGAA |
10 | 23 | -13 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna1800 | UCAAGACCCUC---AACAAGUU AGUUCUGGGAG---UUGUUCAA |
75 | 20 | 55 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 | ||
aspsirna1801 | CAAGACCCUC---AACAAGUUU GUUCUGGGAG---UUGUUCAAA |
30 | 20 | 10 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 | ||
aspsirna1802 | AAGACCCUC---AACAAGUUUG UUCUGGGAG---UUGUUCAAAC |
25 | 5 | 20 | KRT6a | Pachyonychia congenita (PC) | c.514_516delAAC,p.Asn172del | rs26760745 |