ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0876 | ACAGAUCAAGACCCUCAAA UGUCUAGUUCUGGGAGUUU |
36 | 22 | 14 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0877 | CAGAUCAAGACCCUCAAAA GUCUAGUUCUGGGAGUUUU |
56 | 42 | 14 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0878 | AGAUCAAGACCCUCAAAAA UCUAGUUCUGGGAGUUUUU |
39 | 20 | 19 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0879 | GAUCAAGACCCUCAAAAAC CUAGUUCUGGGAGUUUUUG |
56 | 42 | 14 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0880 | AUCAAGACCCUCAAAAACA UAGUUCUGGGAGUUUUUGU |
67 | 39 | 28 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0881 | UCAAGACCCUCAAAAACAA AGUUCUGGGAGUUUUUGUU |
89 | 10 | 79 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0882 | CAAGACCCUCAAAAACAAG GUUCUGGGAGUUUUUGUUC |
30 | 2 | 28 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0883 | AAGACCCUCAAAAACAAGU UUCUGGGAGUUUUUGUUCA |
33 | 0 | 33 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0884 | AGACCCUCAAAAACAAGUU UCUGGGAGUUUUUGUUCAA |
35 | 10 | 25 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0885 | GACCCUCAAAAACAAGUUU CUGGGAGUUUUUGUUCAAA |
59 | 0 | 59 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0886 | ACCCUCAAAAACAAGUUUG UGGGAGUUUUUGUUCAAAC |
13 | 0 | 13 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0887 | CCCUCAAAAACAAGUUUGC GGGAGUUUUUGUUCAAACG |
35 | 0 | 35 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0888 | CCUCAAAAACAAGUUUGCC GGAGUUUUUGUUCAAACGG |
45 | 9 | 36 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0889 | CUCAAAAACAAGUUUGCCU GAGUUUUUGUUCAAACGGA |
56 | 25 | 31 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0890 | UCAAAAACAAGUUUGCCUC AGUUUUUGUUCAAACGGAG |
45 | 10 | 35 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0891 | CAAAAACAAGUUUGCCUCC GUUUUUGUUCAAACGGAGG |
23 | 20 | 3 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0892 | AAAAACAAGUUUGCCUCCU UUUUUGUUCAAACGGAGGA |
53 | 34 | 19 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0893 | AAAACAAGUUUGCCUCCUU UUUUGUUCAAACGGAGGAA |
47 | 20 | 27 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 | ||
aspsirna0894 | AAACAAGUUUGCCUCCUUC UUUGUUCAAACGGAGGAAG |
34 | 9 | 25 | KRT6a | Pachyonychia congenita (PC) | c.513C>A,p.Asn171Lys | rs59685571 |