ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0041 | GAGAUGGGGACAGUACUUC CUCUACCCCUGUCAUGAAG |
70 | 28 | 42 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ||
aspsirna0042 | GAGAUGGGGACAGUAAUUC CUCUACCCCUGUCAUUAAG |
70 | 22 | 48 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ||
aspsirna0043 | GGACAGUACUUCAACGCUA CCUGUCAUGAAGUUGCGAU |
94 | 50 | 44 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ||
aspsirna0044 | GGACAGUAAUUCAACGCUA CCUGUCAUUAAGUUGCGAU |
50 | 92 | -42 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ||
aspsirna0045 | GGACAGUACAUCAACGCUA CCUGUCAUGUAGUUGCGAU |
90 | 60 | 30 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ||
aspsirna0046 | GGACAGUAAGUCAACGCUA CCUGUCAUUCAGUUGCGAU |
55 | 82 | -27 | HTT | Huntington disease (HD) | c.5165C>A,c.52CAG(36_39) | rs363125 | ||
aspsirna0047 | GCCUGCUCCCUCAUCUACU CGGACGAGGGAGUAGAUGA |
90 | 70 | 20 | HTT | Huntington disease (HD) | c.6931T>C,c.52CAG(36_39) | rs362331 | ||
aspsirna0048 | GCCUGCUCCCUCAUCCACU CGGACGAGGGAGUAGGUGA |
52 | 90 | -38 | HTT | Huntington disease (HD) | c.6931T>C,c.52CAG(36_39) | rs362331 | ||
aspsirna0049 | UCCCUCAUCUACUGUGUGC AGGGAGUAGAUGACACACG |
70 | 0 | 70 | HTT | Huntington disease (HD) | c.6931T>C,c.52CAG(36_39) | rs362331 | ||
aspsirna0050 | UCCCUCAUCCACUGUGUGC AGGGAGUAGGUGACACACG |
22 | 70 | -48 | HTT | Huntington disease (HD) | c.6931T>C,c.52CAG(36_39) | rs362331 | ||
aspsirna0051 | AUCUACUGUGUGCACUUCA UAGAUGACACACGUGAAGU |
78 | 35 | 43 | HTT | Huntington disease (HD) | c.6931T>C,c.52CAG(36_39) | rs362331 | ||
aspsirna0052 | AUCCACUGUGUGCACUUCA UAGGUGACACACGUGAAGU |
60 | 82 | -22 | HTT | Huntington disease (HD) | c.6931T>C,c.52CAG(36_39) | rs362331 | ||
aspsirna0053 | GUUUGAGCUGAUGUAUGUG CAAACUCGACUACAUACAC |
90 | 20 | 70 | HTT | Huntington disease (HD) | c.8163G>A,c.52CAG(36_39) | rs2276881 | ||
aspsirna0054 | GUUUGAGCUAAUGUAUGUG CAAACUCGAUUACAUACAC |
34 | 23 | 11 | HTT | Huntington disease (HD) | c.8163G>A,c.52CAG(36_39) | rs2276881 | ||
aspsirna0055 | GUUUGAGCCGAUGUAUGUG CAAACUCGGCUACAUACAC |
32 | 30 | 2 | HTT | Huntington disease (HD) | c.8163G>A,c.52CAG(36_39) | rs2276881 | ||
aspsirna0056 | GUUUGAGCCAAUGUAUGUG CAAACUCGGUUACAUACAC |
0 | 22 | -22 | HTT | Huntington disease (HD) | c.8163G>A,c.52CAG(36_39) | rs2276881 | ||
aspsirna0057 | GCUGAUGUAUGUGACGCUG CGACUACAUACACUGCGAC |
92 | 58 | 34 | HTT | Huntington disease (HD) | c.8163G>A,c.52CAG(36_39) | rs2276881 | ||
aspsirna0058 | GCUAAUGUAUGUGACGCUG CGAUUACAUACACUGCGAC |
92 | 58 | 34 | HTT | Huntington disease (HD) | c.8163G>A,c.52CAG(36_39) | rs2276881 |