ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0775 | CAGCAGCAGCAGCAGUAGC GUCGUCGUCGUCGUCAUCG |
45 | 20 | 25 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0776 | CAGCAGCAGCAGCAUCAGC GUCGUCGUCGUCGUAGUCG |
15 | 10 | 5 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0777 | CAGCAGCAGCAGCUGCAGC GUCGUCGUCGUCGACGUCG |
20 | 90 | -70 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0778 | CAGCAGCAGCAGUAGCAGC GUCGUCGUCGUCAUCGUCG |
30 | 30 | 0 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0779 | CAGCAGCAGCAUCAGCAGC GUCGUCGUCGUAGUCGUCG |
66 | 20 | 46 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0780 | CAGCAGCAGCUGCAGCAGC GUCGUCGUCGACGUCGUCG |
60 | 20 | 40 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0781 | CAGCAGCAGUAGCAGCAGC GUCGUCGUCAUCGUCGUCG |
50 | 40 | 10 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0782 | CAGCAGCAGAAGCAGCAGC GUCGUCGUCUUCGUCGUCG |
30 | 35 | -5 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0783 | CAGCAGCAUCAGCAGCAGC GUCGUCGUAGUCGUCGUCG |
48 | 52 | -4 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0784 | CAGCAGCUGCAGCAGCAGC GUCGUCGACGUCGUCGUCG |
88 | 55 | 33 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0785 | CAGCAGUAGCAGCAGCAGC GUCGUCAUCGUCGUCGUCG |
87 | 80 | 7 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0786 | CAGUAGCAGCAGCAGCAGC GUCAUCGUCGUCGUCGUCG |
93 | 30 | 63 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0787 | CAGCAGCAGUUGCAGCAGC GUCGUCGUCAACGUCGUCG |
60 | 20 | 40 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0788 | CAGCAGCAUUUGCAGCAGC GUCGUCGUAAACGUCGUCG |
80 | 30 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0789 | CAGCAGCAUUUUCAGCAGC GUCGUCGUAAAAGUCGUCG |
78 | 25 | 53 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0790 | CAGUAGCAGUAGCAGUAGC GUCAUCGUCAUCGUCAUCG |
70 | 30 | 40 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0791 | CAACAGUAGCAACAGCUGC GUUGUCAUCGUUGUCGACG |
88 | 25 | 63 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0792 | CAGCAGCAGCUGCAGCAGC GUCGUCGUCGUCGUCGUCG |
85 | 60 | 25 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0793 | CAGCAGCAGUAGCAGCAGC GUCGUCGUCGUCGUCGUCG |
80 | 70 | 10 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0794 | CAGCAGCAGUUGCAGCAGC GUCGUCGUCGUCGUCGUCG |
79 | 26 | 53 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0795 | CAGCAGCAGCAGCAGCAGC GUCGUCGUCGACGUCGUCG |
85 | 22 | 63 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0796 | CAGCAGCAGCAGCAGCAGC GUCGUCGUCAUCGUCGUCG |
62 | 17 | 45 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0797 | CAGCAGCAGCAGCAGCAGC GUCGUCGUCUUCGUCGUCG |
90 | 15 | 75 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0798 | CAGCAGCAGCAGCAGCAGC GUCGUCGUAGUCGUCGUCG |
70 | 40 | 30 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0799 | CAGCAGCAGCAGCAGCAGC GUCGUCGUCAACGUCGUCG |
78 | 20 | 58 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0800 | GCAGCAGCAGCAGCAGCAG CGUCGUCGUAGUCGUCGUC |
84 | 15 | 69 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 | ||
aspsirna0801 | AGCAGCAGCAGCAGCAGCA UCGUCGUCGACGUCGUCGU |
69 | NA | NA | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |