ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0428 | GUGGUUGGUAAAGCCUCAG CACCAACCAUUUCGGAGUC |
63 | 93 | -30 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0429 | UGUGGUUGGUAAAGCCUCA ACACCAACCAUUUCGGAGU |
53 | 8 | 45 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0430 | UUGUGGUUGGUAAAGCCUC AACACCAACCAUUUCGGAG |
54 | 28 | 26 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0431 | GUUGUGGUUGGUAAAGCCU CAACACCAACCAUUUCGGA |
72 | 28 | 44 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0432 | UGUUGUGGUUGGUAAAGCC ACAACACCAACCAUUUCGG |
38 | 14 | 24 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0433 | GUGUUGUGGUUGGUAAAGC CACAACACCAACCAUUUCG |
90 | 15 | 75 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0434 | AGUGUUGUGGUUGGUAAAG UCACAACACCAACCAUUUC |
73 | 40 | 33 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0435 | CAGUGUUGUGGUUGGUAAA GUCACAACACCAACCAUUU |
69 | 29 | 40 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0436 | ACAGUGUUGUGGUUGGUAA UGUCACAACACCAACCAUU |
63 | 17 | 46 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0437 | UACAGUGUUGUGGUUGGUA AUGUCACAACACCAACCAU |
65 | 7 | 58 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0438 | CUACAGUGUUGUGGUUGGU GAUGUCACAACACCAACCA |
0 | 0 | 0 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0439 | UCUACAGUGUUGUGGUUGG AGAUGUCACAACACCAACC |
0 | 0 | 0 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0440 | UUCUACAGUGUUGUGGUUG AAGAUGUCACAACACCAAC |
37 | 0 | 37 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0441 | UUUCUACAGUGUUGUGGUU AAAGAUGUCACAACACCAA |
15 | 0 | 15 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0442 | UUUUCUACAGUGUUGUGGU AAAAGAUGUCACAACACCA |
83 | 0 | 83 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0443 | AUUUUCUACAGUGUUGUGG UAAAAGAUGUCACAACACC |
6 | 0 | 6 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0444 | CAUUUUCUACAGUGUUGUG GUAAAAGAUGUCACAACAC |
82 | 0 | 82 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0445 | UCAUUUUCUACAGUGUUGU AGUAAAAGAUGUCACAACA |
80 | 22 | 58 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 | ||
aspsirna0446 | UUCAUUUUCUACAGUGUUG AAGUAAAAGAUGUCACAAC |
70 | 0 | 70 | PSEN1 | Alzheimers disease | c.811C>G, p.Leu271Val | rs63750886 |