ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna0171 | AAGAAACUAUGCAAAAUCC UUCUUUGAUACGUUUUAGG |
74 | 67 | 7 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0172 | AGAAACUAUGCAAAAUCCU UCUUUGAUACGUUUUAGGA |
82 | 60 | 22 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0173 | GAAACUAUGCAAAAUCCUA CUUUGAUACGUUUUAGGAU |
88 | 65 | 23 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0174 | AAACUAUGCAAAAUCCUAA UUUGAUACGUUUUAGGAUU |
70 | 70 | 0 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0175 | AACUAUGCAAAAUCCUAAU UUGAUACGUUUUAGGAUUA |
65 | 30 | 35 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0176 | ACUAUGCAAAAUCCUAAUG UGAUACGUUUUAGGAUUAC |
75 | 56 | 19 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0177 | CUAUGCAAAAUCCUAAUGA GAUACGUUUUAGGAUUACU |
82 | 10 | 72 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0178 | UAUGCAAAAUCCUAAUGAU AUACGUUUUAGGAUUACUA |
96 | 82 | 14 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0179 | AUGCAAAAUCCUAAUGAUA UACGUUUUAGGAUUACUAU |
85 | 58 | 27 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0180 | UGCAAAAUCCUAAUGAUAG ACGUUUUAGGAUUACUAUC |
86 | 10 | 76 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0181 | GCAAAAUCCUAAUGAUAGA CGUUUUAGGAUUACUAUCU |
92 | 60 | 32 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0182 | CAAAAUCCUAAUGAUAGAU GUUUUAGGAUUACUAUCUA |
96 | 25 | 71 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0183 | AAAAUCCUAAUGAUAGAUU UUUUAGGAUUACUAUCUAA |
96 | 70 | 26 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0184 | AAAUCCUAAUGAUAGAUUA UUUAGGAUUACUAUCUAAU |
97 | 28 | 69 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0185 | AAUCCUAAUGAUAGAUUAG UUAGGAUUACUAUCUAAUC |
87 | 11 | 76 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0186 | AUCCUAAUGAUAGAUUAGC UAGGAUUACUAUCUAAUCG |
95 | 72 | 23 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0187 | UCCUAAUGAUAGAUUAGCU AGGAUUACUAUCUAAUCGA |
87 | 40 | 47 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0188 | CCUAAUGAUAGAUUAGCUU GGAUUACUAUCUAAUCGAA |
80 | 50 | 30 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 | ||
aspsirna0189 | CUAAUGAUAGAUUAGCUUC GAUUACUAUCUAAUCGAAG |
88 | 60 | 28 | KRT12 | Meesmann epithelial corneal dystrophy (MECD) | c.409G>C,p.Ala137Pro | rs58038639 |