| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna0688 | GCAGCAGCAGCGGGACCUA CGUCGUCGUCGCCCUGGAU |
80 | 40 | 40 | ATXN3 | Spino Cerebellar Ataxia type-3 (SCA-3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs12895357 | 
|
|
| aspsirna0689 | GCAGCAGCAGCGGGACCUC CGUCGUCGUCGCCCUGGAU |
86 | 15 | 71 | ATXN3 | Spino Cerebellar Ataxia type-3 (SCA-3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs12895357 |
|
|
| aspsirna0690 | GCAGCAGCAGCGGGACCUA CGUCGUCGUCGCCCUGGAU |
45 | 85 | -40 | ATXN3 | Spino Cerebellar Ataxia type-3 (SCA-3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs12895357 |
|
|
| aspsirna0691 | GCAGCAGCAGCGGGACCUAUCAGGACA CGUCGUCGUCGCCCUGGAUAGUCCUGU |
70 | 24 | 46 | ATXN3 | Spino Cerebellar Ataxia type-3 (SCA-3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs12895357 |
|
|
| aspsirna0692 | CAGCAGCAGCGGGACCUAG GUCGUCGUCGCCCUGGAUA |
62 | 40 | 22 | ATXN3 | Spino Cerebellar Ataxia type-3 (SCA-3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs12895357 |
|
|
| aspsirna0693 | GCAGCAGCGGGACCUAUCA CGUCGUCGCCCUGGAUAGU |
70 | 50 | 20 | ATXN3 | Spino Cerebellar Ataxia type-3 (SCA-3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs12895357 |
|
|
| aspsirna0694 | CAGCGGGACCUAUCAGGAA GUCGCCCUGGAUAGUCCUG |
70 | 38 | 32 | ATXN3 | Spino Cerebellar Ataxia type-3 (SCA-3) | c.892_894CAG(8_36) (p.Gln298_Gln305=) | rs12895357 |
|
|
| aspsirna0695 | CAGUGGCUCACCAGAUUAC GUCACCGAGUGGUCUAAUG |
72 | 30 | 42 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0696 | CAGUGGCUCCCCUGAUUAC GUCACCGAGGGGACUAAUG |
76 | 20 | 56 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0697 | CAGUGGCUCCCUACAUUAC GUCACCGAGGGAUGUAAUG |
80 | 16 | 64 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0698 | CAGUGGCUCCCCAAUUUAC GUCACCGAGGGGUUAAAUG |
85 | 40 | 45 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0699 | AGAUUUGGACCUGGCAGUC UCUAAACCUGGACCGUCAG |
75 | 25 | 50 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0700 | AGACUUGGACCAGGCAGUC UCUGAACCUGGUCCGUCAG |
10 | 48 | -38 | HTT | Huntington disease (HD) | c.52CAG(36_39) | rs19392295 |
|
|
| aspsirna0701 | CCAAGAAAGCCGAGAGCAU GGUUCUUUCGGCUCUCGUC |
0 | 24 | -24 | ATXN1 | Spino Cerebellar Ataxia type-1 (SCA-1) | c.589_591CAG(36_38),p.Gln208_His209 | rs19392292 |
|
|
| aspsirna0702 | CAAGAAAGCCGAGAGCAGA GUUCUUUCGGCUCUCGUCG |
0 | 20 | -20 | ATXN1 | Spino Cerebellar Ataxia type-1 (SCA-1) | c.589_591CAG(36_38),p.Gln208_His209 | rs19392292 |
|
|
| aspsirna0703 | AAGAAAGCCGAGAGCAGUA UUCUUUCGGCUCUCGUCGG |
58 | 32 | 26 | ATXN1 | Spino Cerebellar Ataxia type-1 (SCA-1) | c.589_591CAG(36_38),p.Gln208_His209 | rs19392292 |
|
|
| aspsirna0704 | AGCCGAGAGCAGCCGGCUU UCGGCUCUCGUCGGCCGAC |
47 | 78 | -31 | ATXN1 | Spino Cerebellar Ataxia type-1 (SCA-1) | c.589_591CAG(36_38),p.Gln208_His209 | rs19392292 |
|