ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3162 | CAACGACGUUUACGACGACGAC GUUGCUGCAAAUGCUGCUGCUG |
50 | 20 | 30 | HTT | Huntington disease (HD) | (CAG)81 | NA | ||
aspsirna3163 | CAACGACGUCGACGACGACGAC GUUGCUGCAGCUGCUGCUGCUG |
82 | 50 | 32 | HTT | Huntington disease (HD) | (CAG)81 | NA | ||
aspsirna3164 | CAACGACGAUGACGACGACGAC GUUGCUGCUACUGCUGCUGCUG |
95 | 90 | 5 | HTT | Huntington disease (HD) | (CAG)81 | NA | ||
aspsirna3165 | UCCCUCCUGCAGGCUGGCUGUU AGGGAGGACGUCCGACCGACAA |
70 | 20 | 50 | HTT | Huntington disease (HD) | rs362268 | rs362268 | ||
aspsirna3166 | UCCCUCCUGCAGGCUGCGUGUU AGGGAGGACGUCCGACGCACAA |
55 | 25 | 30 | HTT | Huntington disease (HD) | rs362268 | rs362268 | ||
aspsirna3167 | UUGCCAGGUUGCAGCUGCUCUU AACGGUCCAACGUCGACGAGAA |
70 | 20 | 50 | HTT | Huntington disease (HD) | rs362306 | rs362306 | ||
aspsirna3168 | UUUGGAAGUCUGUGCCCUUGUA AAACCUUCAGACACGGGAACAU |
78 | 20 | 58 | HTT | Huntington disease (HD) | rs362306 | rs362307 | ||
aspsirna3169 | UUUGGAAGUCUUCGCCCUUGUA AAACCUUCAGAAGCGGGAACAU |
85 | 33 | 52 | HTT | Huntington disease (HD) | rs362306 | rs362307 | ||
aspsirna3170 | CAACGACGUUUACGACGACGAC GUUGCUGCAAAUGCUGCUGCUG |
45 | 27 | 18 | HTT | Huntington disease (HD) | (CAG)81 | NA | ||
aspsirna3171 | CAACGACGUCGACGACGACGAC GUUGCUGCAGCUGCUGCUGCUG |
77 | 50 | 27 | HTT | Huntington disease (HD) | (CAG)81 | NA | ||
aspsirna3172 | CAACGACGAUGACGACGACGAC GUUGCUGCUACUGCUGCUGCUG |
80 | 90 | -10 | HTT | Huntington disease (HD) | (CAG)81 | NA | ||
aspsirna3173 | UCCCUCCUGCAGGCUGGCUGUU AGGGAGGACGUCCGACCGACAA |
70 | 20 | 50 | HTT | Huntington disease (HD) | rs362268 | rs362268 | ||
aspsirna3174 | UCCCUCCUGCAGGCUGCGUGUU AGGGAGGACGUCCGACGCACAA |
60 | 25 | 35 | HTT | Huntington disease (HD) | rs362268 | rs362268 | ||
aspsirna3175 | UUGCCAGGUUGCAGCUGCUCUU AACGGUCCAACGUCGACGAGAA |
70 | 20 | 50 | HTT | Huntington disease (HD) | rs362306 | rs362306 | ||
aspsirna3176 | UUUGGAAGUCUGUGCCCUUGUA AAACCUUCAGACACGGGAACAU |
80 | 20 | 60 | HTT | Huntington disease (HD) | rs362307 | rs362307 | ||
aspsirna3177 | UUUGGAAGUCUUCGCCCUUGUA AAACCUUCAGAAGCGGGAACAU |
70 | 30 | 40 | HTT | Huntington disease (HD) | rs362307 | rs362307 | ||
aspsirna3178 | UUGCCAGGUUGCAGCUGCUCUU AACGGUCCAACGUCGACGAGAA |
90 | 26 | 64 | HTT | Huntington disease (HD) | rs362306 | rs362306 |