| ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
|---|---|---|---|---|---|---|---|---|---|---|
| ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
| aspsirna2939 | CAUAGUCAUUUCUAAAAGU GUAUCAGUAAAGAUUUUCA |
90 | 20 | 70 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA | 
|
|
| aspsirna2940 | CACUAGUAGAAAGUAUAAU GUGAUCAUCUUUCAUAUUA |
85 | 20 | 65 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2941 | GUAGAAAGUAUAAUUUCAA CAUCUUUCAUAUUAAAGUU |
10 | 20 | -10 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2942 | AGUCAUUUCUAAAAGUCAC UCAGUAAAGAUUUUCAGUG |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2943 | UUCUAAAAGUCACUAGUAG AAGAUUUUCAGUGAUCAUC |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2944 | AAAAGUCACUAGUAGAAAG UUUUCAGUGAUCAUCUUUC |
78 | 20 | 58 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2945 | CAUAGUCAUAUCUAAAAGU GUAUCAGUAUAGAUUUUCA |
30 | 20 | 10 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2946 | CAUAGUCAUGUCUAAAAGU GUAUCAGUACAGAUUUUCA |
40 | 20 | 20 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2947 | CACUAGUAGUAAGUAUAAU GUGAUCAUCAUUCAUAUUA |
45 | 20 | 25 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2948 | CACUAGUAGGAAGUAUAAU GUGAUCAUCCUUCAUAUUA |
50 | 20 | 30 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2949 | CACUAGUAGCAAGUAUAAU GUGAUCAUCGUUCAUAUUA |
50 | 20 | 30 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2950 | UUCUAAAAGACACUAGUAG AAGAUUUUCUGUGAUCAUC |
33 | 20 | 13 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2951 | UUCUAAAAGGCACUAGUAG AAGAUUUUCCGUGAUCAUC |
30 | 20 | 10 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2952 | GGAUUUAUGUGGAUACAAA CCUAAAUACACCUAUGUUU |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2953 | GAUUUAUGUGGAUACAAAU CUAAAUACACCUAUGUUUA |
96 | 15 | 81 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2954 | GAUACAAAUUCUCCUUUAAA CUAUGUUUAAGAGGAAAUUU |
98 | 15 | 83 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2955 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2956 | UCCUUUAAAGUGUUUCUUC AGGAAAUUUCACAAAGAAG |
20 | 15 | 5 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2957 | UUCCCUUAAUAUUUAUCUG AAGGGAAUUAUAAAUAGAC |
20 | 15 | 5 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2958 | UUUAUGUGGAUACAAAUUC AAAUACACCUAUGUUUAAG |
45 | 15 | 30 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2959 | UUAUGUGGAUACAAAUUCU AAUACACCUAUGUUUAAGA |
80 | 15 | 65 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2960 | UAUGUGGAUACAAAUUCUC AUACACCUAUGUUUAAGAG |
55 | 15 | 40 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2961 | AUGUGGAUACAAAUUCUCC UACACCUAUGUUUAAGAGG |
45 | 15 | 30 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2962 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2963 | GGAUUUAUGAGGAUACAAA CCUAAAUACUCCUAUGUUU |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2964 | GGAUUUAUGGGGAUACAAA CCUAAAUACCCCUAUGUUU |
96 | 15 | 81 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2965 | CAUAGUCAUUUCUAAAAGU GUAUCAGUAAAGAUUUUCA |
70 | 20 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2966 | CACUAGUAGAAAGUAUAAU GUGAUCAUCUUUCAUAUUA |
70 | 20 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2967 | GUAGAAAGUAUAAUUUCAA CAUCUUUCAUAUUAAAGUU |
75 | 20 | 55 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2968 | AGUCAUUUCUAAAAGUCAC UCAGUAAAGAUUUUCAGUG |
40 | 20 | 20 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2969 | UUCUAAAAGUCACUAGUAG AAGAUUUUCAGUGAUCAUC |
55 | 20 | 35 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2970 | AAAAGUCACUAGUAGAAAG UUUUCAGUGAUCAUCUUUC |
45 | 20 | 25 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2971 | CAUAGUCAUAUCUAAAAGU GUAUCAGUAUAGAUUUUCA |
20 | 20 | 0 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2972 | CAUAGUCAUGUCUAAAAGU GUAUCAGUACAGAUUUUCA |
30 | 20 | 10 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2973 | CACUAGUAGUAAGUAUAAU GUGAUCAUCAUUCAUAUUA |
38 | 20 | 18 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2974 | CACUAGUAGGAAGUAUAAU GUGAUCAUCCUUCAUAUUA |
45 | 20 | 25 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2975 | CACUAGUAGCAAGUAUAAU GUGAUCAUCGUUCAUAUUA |
24 | 20 | 4 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2976 | UUCUAAAAGACACUAGUAG AAGAUUUUCUGUGAUCAUC |
20 | 20 | 0 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2977 | UUCUAAAAGGCACUAGUAG AAGAUUUUCCGUGAUCAUC |
25 | 20 | 5 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2978 | GGAUUUAUGUGGAUACAAA CCUAAAUACACCUAUGUUU |
86 | 15 | 71 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2979 | GAUUUAUGUGGAUACAAAU CUAAAUACACCUAUGUUUA |
88 | 15 | 73 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2980 | GAUACAAAUUCUCCUUUAAA CUAUGUUUAAGAGGAAAUUU |
85 | 15 | 70 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2981 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
80 | 15 | 65 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2982 | UCCUUUAAAGUGUUUCUUC AGGAAAUUUCACAAAGAAG |
20 | 15 | 5 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2983 | UUCCCUUAAUAUUUAUCUG AAGGGAAUUAUAAAUAGAC |
15 | 15 | 0 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2984 | UUUAUGUGGAUACAAAUUC AAAUACACCUAUGUUUAAG |
50 | 15 | 35 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2985 | UUAUGUGGAUACAAAUUCU AAUACACCUAUGUUUAAGA |
80 | 15 | 65 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2986 | UAUGUGGAUACAAAUUCUC AUACACCUAUGUUUAAGAG |
65 | 15 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2987 | AUGUGGAUACAAAUUCUCC UACACCUAUGUUUAAGAGG |
20 | 15 | 5 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2988 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
75 | 15 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2989 | GGAUUUAUGAGGAUACAAA CCUAAAUACUCCUAUGUUU |
80 | 15 | 65 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2990 | GGAUUUAUGGGGAUACAAA CCUAAAUACCCCUAUGUUU |
76 | 15 | 61 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2991 | CACUAGUAGUAAGUAUAAU GUGAUCAUCAUUCAUAUUA |
40 | 20 | 20 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2992 | UAUGUGGAUACAAAUUCUC AUACACCUAUGUUUAAGAG |
35 | 15 | 20 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2993 | CACUAGUAGUAAGUAUAAU GUGAUCAUCAUUCAUAUUA |
50 | 15 | 35 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2994 | UAUGUGGAUACAAAUUCUC AUACACCUAUGUUUAAGAG |
30 | 13 | 17 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2995 | CAUAGUCAUUUCUAAAAGU GUAUCAGUAAAGAUUUUCA |
95 | 20 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2996 | CACUAGUAGAAAGUAUAAU GUGAUCAUCUUUCAUAUUA |
90 | 20 | 70 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2997 | GUAGAAAGUAUAAUUUCAA CAUCUUUCAUAUUAAAGUU |
93 | 20 | 73 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2998 | AGUCAUUUCUAAAAGUCAC UCAGUAAAGAUUUUCAGUG |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna2999 | UUCUAAAAGUCACUAGUAG AAGAUUUUCAGUGAUCAUC |
85 | 20 | 65 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3000 | AAAAGUCACUAGUAGAAAG UUUUCAGUGAUCAUCUUUC |
88 | 20 | 68 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3001 | CAUAGUCAUAUCUAAAAGU GUAUCAGUAUAGAUUUUCA |
70 | 20 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3002 | CAUAGUCAUGUCUAAAAGU GUAUCAGUACAGAUUUUCA |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3003 | CACUAGUAGUAAGUAUAAU GUGAUCAUCAUUCAUAUUA |
55 | 20 | 35 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3004 | CACUAGUAGGAAGUAUAAU GUGAUCAUCCUUCAUAUUA |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3005 | CACUAGUAGCAAGUAUAAU GUGAUCAUCGUUCAUAUUA |
70 | 20 | 50 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3006 | UUCUAAAAGACACUAGUAG AAGAUUUUCUGUGAUCAUC |
80 | 20 | 60 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3007 | UUCUAAAAGGCACUAGUAG AAGAUUUUCCGUGAUCAUC |
90 | 20 | 70 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3008 | GGAUUUAUGUGGAUACAAA CCUAAAUACACCUAUGUUU |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3009 | GAUUUAUGUGGAUACAAAU CUAAAUACACCUAUGUUUA |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3010 | GAUACAAAUUCUCCUUUAAA CUAUGUUUAAGAGGAAAUUU |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3011 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
98 | 15 | 83 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3012 | UCCUUUAAAGUGUUUCUUC AGGAAAUUUCACAAAGAAG |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3013 | UUCCCUUAAUAUUUAUCUG AAGGGAAUUAUAAAUAGAC |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3014 | UUUAUGUGGAUACAAAUUC AAAUACACCUAUGUUUAAG |
98 | 15 | 83 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3015 | UUAUGUGGAUACAAAUUCU AAUACACCUAUGUUUAAGA |
95 | 15 | 80 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3016 | UAUGUGGAUACAAAUUCUC AUACACCUAUGUUUAAGAG |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3017 | AUGUGGAUACAAAUUCUCC UACACCUAUGUUUAAGAGG |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3018 | UGUGGAUACAAAUUCUCCU ACACCUAUGUUUAAGAGGA |
88 | 15 | 73 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3019 | GGAUUUAUGAGGAUACAAA CCUAAAUACUCCUAUGUUU |
90 | 15 | 75 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3020 | AAGGAUUUAUGGGGAUACAAA UUCCUAAAUACCCCUAUGUUU |
96 | 15 | 81 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3021 | CAUAGUCAUAUCAAAAAGU GUAUCAGUAUAGUUUUUCA |
10 | 8 | 2 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3022 | CAUAGUCAUAUCUUAAAGU GUAUCAGUAUAGAAUUUCA |
15 | 8 | 7 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3023 | CAUAGUCAUAUCUAUAAGU GUAUCAGUAUAGAUAUUCA |
10 | 8 | 2 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3024 | CACUAGUAGUAACUAUAAU GUGAUCAUCAUUGAUAUUA |
15 | 8 | 7 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3025 | CACUAGUAGUAAGAAUAAU GUGAUCAUCAUUCUUAUUA |
15 | 8 | 7 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|
|
| aspsirna3026 | CACUAGUAGUAAGUUUAAU GUGAUCAUCAUUCAAAUUA |
20 | 8 | 12 | SNCA | Parkinsons disease (PD) | SNCA locus triplication | NA |
|