ASPsiRNA ID | Pairing of target region (top) and ASP-siRNA (bottom) | Efficacy (mut)(%) | Efficacy (wt) (%) | Diff | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
---|---|---|---|---|---|---|---|---|---|---|
ASPsiRNA ID | Mutant allele/ASP-siRNA | Efficacy for mutant(%) |
Efficacy for wild (%) |
Relative Difference (%) | Gene | Disease | Mutation | RefSNP | Analysis | Pubmed ID |
aspsirna3240 | CUCGGCUGGCCUCUUGGCU GAGCCGACCGGAGAACCGA |
10 | 0 | 10 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3241 | UCGGCUGGCCUCUUGGCUC AGCCGACCGGAGAACCGAG |
30 | 10 | 20 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3242 | CGGCUGGCCUCUUGGCUCU GCCGACCGGAGAACCGAGA |
10 | 0 | 10 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3243 | GGCUGGCCUCUUGGCUCUU CCGACCGGAGAACCGAGAA |
20 | 3 | 17 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3244 | GCUGGCCUCUUGGCUCUUG CGACCGGAGAACCGAGAAC |
10 | 0 | 10 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3245 | CUGGCCUCUUGGCUCUUGG GACCGGAGAACCGAGAACC |
2 | 10 | -8 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3246 | UGGCCUCUUGGCUCUUGGA ACCGGAGAACCGAGAACCU |
40 | 20 | 20 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3247 | GGCCUCUUGGCUCUUGGAU CCGGAGAACCGAGAACCUA |
70 | 5 | 65 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3248 | GCCUCUUGGCUCUUGGAUA CGGAGAACCGAGAACCUAU |
30 | 15 | 15 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3249 | CCUCUUGGCUCUUGGAUAA GGAGAACCGAGAACCUAUU |
42 | 30 | 12 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3250 | CUCUUGGCUCUUGGAUAAG GAGAACCGAGAACCUAUUC |
35 | 22 | 13 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3251 | UCUUGGCUCUUGGAUAAGG AGAACCGAGAACCUAUUCC |
20 | 10 | 10 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3252 | CUUGGCUCUUGGAUAAGGU GAACCGAGAACCUAUUCCA |
11 | 10 | 1 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3253 | UUGGCUCUUGGAUAAGGUG AACCGAGAACCUAUUCCAC |
22 | 13 | 9 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3254 | UGGCUCUUGGAUAAGGUGC ACCGAGAACCUAUUCCACG |
0 | 20 | -20 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3255 | GGCUCUUGGAUAAGGUGCA CCGAGAACCUAUUCCACGU |
30 | 24 | 6 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3256 | GGCCUCUUGGCUCUUGGAU CCGGAGAACCGAGAACCUA |
80 | 0 | 80 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3257 | GGCCUCUUGGCUCUUGGAU CCGGAGAACCGAGAACCUA |
80 | 2 | 78 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3258 | GGCCUCUUGGCUCUUGGAU CCGGAGAACCGAGAACCUA |
80 | 2 | 78 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 | ||
aspsirna3259 | GGCCUCUUGGCUCUUGGAU CCGGAGAACCGAGAACCUA |
73 | 10 | 63 | KRT9 | Epidermolytic palmoplantar keratoderma (EPPK) | c.500delAinsGGCT,p.Tyr167delinsTrpLeu | rs59317143 |